In this presentation viewers will able to learn about liquids for external use such as liniments and lotions, liquids for oral cavity such as mouthwash, throat paints and gargles.
A suppository is a drug delivery system that is inserted into the rectum (rectal suppository), vagina (vaginal suppository) or urethra (urethral suppository), where it dissolves or melts and is absorbed into the blood stream. They are used to deliver both systemically and locally acting medications.
Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms
A suppository is a drug delivery system that is inserted into the rectum (rectal suppository), vagina (vaginal suppository) or urethra (urethral suppository), where it dissolves or melts and is absorbed into the blood stream. They are used to deliver both systemically and locally acting medications.
Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms
Semisolid dosage forms are neither solid nor liquid, however, they are a combination or mixture of both, and they used for both local and systemic effects. Pharmaceutical semisolid dosage forms such as creams, ointments, gels, suppositories, and paste are used for topical application. Semisolid dosage forms are intended used as drug carriers that are transported topically through the skin, buckle tissue, rectal tissue, outer ear lining nasal mucosa, urethral membrane, vagina, and cornea. The semisolid may adhere adequately before washing on the surface of the application; this helps to extend the supply of drugs on the application site.
Liquid preparations having two phases are termed as
biphasic liquids.
DEFINITION, ADVANTAGES AND
DISADVANTAGES, CLASSIFICATIONS,
PREPARATION OF SUSPENSIONS;
FLOCCULATED AND
DEFLOCCULATED SUSPENSION &
STABILITY PROBLEMS AND METHODS
TO OVERCOME
Emulsion
Definition, classification, emulsifying
agent, test for the identification of
type of Emulsion, Methods of
preparation & stability problems and
methods to overcome.
Hi! I made these labels for study purpose. These are not for marketing or something else. i will upload more labels in future.
if you have any trouble downloading these labels. contact me on my email address. Thankyou.
Semisolid dosage forms are neither solid nor liquid, however, they are a combination or mixture of both, and they used for both local and systemic effects. Pharmaceutical semisolid dosage forms such as creams, ointments, gels, suppositories, and paste are used for topical application. Semisolid dosage forms are intended used as drug carriers that are transported topically through the skin, buckle tissue, rectal tissue, outer ear lining nasal mucosa, urethral membrane, vagina, and cornea. The semisolid may adhere adequately before washing on the surface of the application; this helps to extend the supply of drugs on the application site.
Liquid preparations having two phases are termed as
biphasic liquids.
DEFINITION, ADVANTAGES AND
DISADVANTAGES, CLASSIFICATIONS,
PREPARATION OF SUSPENSIONS;
FLOCCULATED AND
DEFLOCCULATED SUSPENSION &
STABILITY PROBLEMS AND METHODS
TO OVERCOME
Emulsion
Definition, classification, emulsifying
agent, test for the identification of
type of Emulsion, Methods of
preparation & stability problems and
methods to overcome.
Hi! I made these labels for study purpose. These are not for marketing or something else. i will upload more labels in future.
if you have any trouble downloading these labels. contact me on my email address. Thankyou.
Pharmaceutical liquid dosage forms - Classification, Types are described- Syrup, elixirs, liniments, lotions, gargles, mouthwash and throat paints. These dosage forms are describes with its preparation method.
This ppt goes out to all the pharmacy students and lecturers. Check my other ppt slides too and do not forget to like and share! :) Thank you for the visit :D
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L-1 Social Pharmacy D.Pharm 1st Year based on the new syllabus of d Pharma as per PCI ER 2020.
Definition of social pharmacy
Social pharmacy as a discipline
Objectives of social pharmacy
Social pharmacy research
Social pharmacy education
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Through this presentation viewers will be able to define Cosmetics, Classify cosmetics on different basis, Explain about various Facial Cosmetics, Such As Face powder, Cold Cream, Vanishing Cream, Cleansing Cream, Lipstick, Various Eye make-up preparations.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
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Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
1. MONOPHASIC LIQUID DOSAGE FORM
Part-4
Mrs. Sandhya R. Lanke (M . Pharm.)
SJVPM’S Rasiklal. M. Dhariwal
College of Pharmacy,
Chinchwad, Pune
2. Learning Outcomes
After watching this presentation, you will be able to;
1. Define Mouthwash, Gargles
2. Compare Liniments and Lotions
3. Discuss Ear Drops, Nasal Drops
3. Liquids To Be Used In Oral
Cavity
Gargles Mouthwash Throat Paint
4. Gargles
Gargles are clear aqueous solutions used to prevent or
treat throat infections.
They are brought into intimate contact with the mucous
membrane of the throat and are allowed to remain in
contact with it for few seconds, before they are thrown
out of the mouth.
5. Gargles
• Gargles may contain antiseptics, analgesics or weak
astringents. The liquid is usually not intended for
swallowing.
• Reason: Gargles are dispensed in concentrated form.
The quantity of solution require for doing one time gargle
is around 20 ml.
Therefore if it is dispensed in dilute form it requires the
large quantity which is practically impossible to dispense.
Therefore they are dispensed in concentrated form.
6. • Potassium chlorate & Phenol Gargle B.P.C.
Rx
Potassium chlorate .........30 g
Patent Blue V .................0.009 g
liquefied phenol .............15 ml
Water up to ....................1000 ml
Gargles
7. • Containers: White fluted glass bottle with plastic screw
cap. Coloured bottle used for preparation which need
protection
• Storage: Store at room temperature, Keep out of the
reach of children. Store away from direct sunlight , heat
and moisture.
• Labelling : “Use only as directed”.
“For external use only”
“Diluted with warm water before use”.
“Not To Be Swallowed”.
Gargles
8. Mouthwash
Mouth wash are aqueous solutions with a pleasant taste
and odour used to clean and deodorize the buccal cavity.
They contains;
• Antibacterial agent,
• Flavouring agents,
• Sweetening agent and
• Colouring agent
9. • Compound sodium chloride mouthwash B.P.C.
Rx
Sodium Bicarbonate..........10g
Sodium Chloride……........15g
Chloroform………..............500ml
Peppermint oil………............25ml
Water…….qty to prepare 1000ml
• Method:
1. Dissolve Sodium bicarbonate with Sodium Chloride in 10 ml
2. Add chloroform & peppermint oil
3. Makeup the volume & Dispense the solution.
Mouthwash
10. Mouthwash and Gargles
Mouthwash
• Mouthwashes are aqueous
solutions with a pleasant taste
and smell for refreshing
effect.
• used to make clean and
deodorise the buccal cavity.
• These are used to rinse buccal
cavity
• More used for cosmetic
purpose
• Ex. Compound Sodium
Chloride Mouthwash
Gargles
• Gargles are aqueous
solutions used to prevent
or treat throat infections.
• Used to relieve soreness in
mild throat infections.
• These are gargled to bring
in intimate contact with
mucus membrane of throat
• used for medicated
purpose.
• Ex. Potassium Chlorate
Gargle
11. Throat Paints
Throat paints are viscous liquid preparations used for
mouth and throat infections.
Commonly used throat paints are boroglycerin, phenol
glycerin, tannic acid glycerin, compound iodine paint.
• Reason: Glycerine is used as base in throat paint.
Glycerin is viscous in nature and adheres to the throat
Increases contact time and prolong the action
It is also act as soothing agent.
12. • Ex. Iodine paint compound( Mandl’s paint ) B.P.C.
Rx
Potassium iodide …………………25.0 g
Iodine ………………….................12.5 g
Alcohol 90% …………………........40.0 ml
Water ….……………...................25.0 ml
Peppermint oil ……….……….....4.0 ml
Glycerine to produce ……..……1000 ml
Throat Paints
13. • Method of Preparation:
(i) Potassium iodide is dissolved in water.
(ii) Iodine is added in the concentrated potassium iodide solutions
to form KI3(or higher iodides).
(iii) Peppermint oil is dissolved in alcohol 90%v/v and the alcoholic
solution is added to the iodine solution.
(iv) Volume is made up with glycerin.
(v) Transfer the preparation into a well closed container, label and
dispense
Throat Paints
14. • Containers: It should be dispensed in airtight, coloured
fluted bottle .Glass stoppers are generally used in such
bottles.
• Labelling: "For External use only"
“Shake the bottle before use”
“Not to be swallowed in large amount”
Throat Paints
15. • Storage:
It should be stored in airtight containers in cool place.
• Directions:
1. Apply with the help of soft brush or a cotton swab.
2. Food and water before and after application of throat
paint, should be avoided for 1 hour
Throat Paints
16. LIQUIDS TO BE INSTILLED INTO BODY CAVITIES
Ear Drop Nasal Drop Douche
17. Ear Drop
Ear drops are solutions of one or more active ingredient
which exert a local effect in the ear, that are instilled into
the ear with dropper.
They may also be referred to as otic or aural preparations.
• Uses:
Treatinfection Tosoftenearwax
Producelocalanaesthesia Reduceearpain
Killinsectlodgedinauditorycanal
18. • Formulation of Ear drop:
The main solvent used in ear drop includes glycerine
propylene glycol and water.
The viscous glycerine solution permits the drug to remain in
ear for longer time.
The viscous liquids such as glycerine or propylene glycol are
used either alone or in combination with surfactant to aid
in the removal of ear wax.
Ear Drop
19. • Ex. Soda glycerine ear drop:
Rx
Sodium carbonate.........5.0gms
Glycerine…………………….. 30.0ml
Purified water q.s ………..100.0ml
• Container:
Ear drop should be packed in colour, fluted glass bottle and
supplied with dropper.
• Labelling: “For external use only” “Not for injection”
“Discontinue the use if irritation persist”
Ear Drop
20. These are aqueous solutions that are instilled into the
nose with dropper to relieve congestion ,inflammation &
to combat infection.
Isotonic saline nasal sprays are commonly used in infants
and children to wash out the thick mucus from the nose in
case of allergic rhinitis.
Nasal Drop
21. • Formulation of nasal drops:
Isotonicity contributor: 0.9% sodium chloride.
Buffer: It should have neutral pH, phosphate buffer, etc
Viscosity Builder/Thickening agents: use of 0.5% methyl
cellulose
Vehicle: Use phosphate buffer of pH 6.5 as vehicle.
Nasal Drop
22. • Reason: Nasal drops made isotonic?
If nasal drops are isotonic it will prevent irritation to
epithelial cilia of nasal mucosa.
• Oily vehicles are not used in the preparation of nasal drop.
Because oily drop inhibits the movement of cilia in the
nasal mucosa and if used for longer periods, may reach to
lung and cause lipoid pneumonia.
Nasal Drop
23. • Ephedrine Nasal Drop B.P.C.
Rx
Ephedrine…………. 0.5 g
Chlorobutal………… 0.5 g
Sodium Chloride…. 0.5 g
Water up to …………1000 ml
Prepare nasal drop, send 30 ml
Direction: Place 2-3 drop in each nostril as directed.
Nasal Drop
24. • Container:
Nasal drop should be packed in colour, fluted glass bottle and
supplied with dropper.
• Labelling:
“For external use only”
• Storage:
These are supplied in well closed glass container in cool place.
Nasal Drop
25. Douches are medicated solutions for rinsing body cavity
mostly for bladder, vagina, rectum, nasal cavity.
Ex. Potassium permanganate douche solution, Isotonic sodium
chloride solution etc.
Douches are available as;
• Eye douche
• Nasal douche
• Pharyngeal douche
• Vaginal Douche
Douche
29. These are alcoholic or oleaginous solution or emulsion of
various medicinal substances intended for external
application to the skin, with friction and rubbing.
• Types of liniments
1. Alcoholic Liniments Used for its rubefacient property.
Ex. Chloroform liniment
2. Oily Liniments Useful when massage is required
Ex. Camphor Liniment BP
3. Emulsion Liniment: Ex. Camphor & Soap Liniment BP
Liniments
30. • Container:
Liniments are dispensed in colored fluted bottles.
• Labeling:
“ For external Use only”
“Apply with Friction”
“ Do not apply on broken Skin”
Liniments
31. Lotions are liquid or semi liquid preparations applied to the
skin or mucus membrane for their cooling, moisturizing
effect.
Lotions are directly applied to the skin or applied with the
help suitable absorbent material like cotton wool
Formulation Additives:
• Antiseptics(zinc oxide, sulphur)
• Astringents( calamine , zinc oxide)
• Anaesthetics (Benzocain )
• Alcohol (Provides the cooling sensation)
• Glycerin (acts as humectant )
Lotions
32. • Calamine Lotion I.P
Rx
Calamine…………….15 g
Zinc oxide ………...5 g
Bentonite …………..3 g
Sodium citrate ……0.5 g
Liquid phenol …….1.5 ml
Glycerin ……………..5 ml
rose water…………. 100 ml
Water …………………q.s.
Lotions
33. • Method Of Preparation:
1. Prepare the sodium citrate solution by dissolving sodium
citrate in one-fourth of total volume of purified water.
2. Triturate the calamine, zinc oxide and Bentonite with
sodium citrate solution, until a smooth cream is obtained.
3. Dilute the cream with the water, to make it pourable
transfer this mixture to a measure
4. Add liquid phenol and glycerin, mix well and adjust the
final volume with the purified water.
Lotions
34. • Container:
• Lotions are dispense in a well closed, narrow mouthed,
amber coloured, fluted plastic bottle, closed with
coloured plastic screw cap .
• The containers which are used for dispensing lotions must
have adequate air space above the lotion .
• Labeling: “ For external Use only”
“Apply without Friction or rubbing”
“ Shake well before use”
Liniments