This document describes research using an artificial neural network (ANN) to model the behavior of a single chamber solid oxide fuel cell (SOFC) without relying on physical equations. Experimental data from a previous study was used to train and validate the ANN model. The ANN was able to adequately predict the cell voltage based on inputs of current density and temperature. Genetic algorithms were then used to optimize the ANN model and determine the operating conditions that achieve maximum power density of 381.54 A/m2 at 687°C and 0.44V cell voltage. The results demonstrate the capabilities of ANNs and genetic algorithms for modeling and optimizing SOFC performance without detailed physical knowledge.