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MILESTONES IN MEDICINE
       WALID MAANI
 THE UNIVERSITY OF JORDAN
Milestones In Medicine?

    Difficult to choose.

   Advances in 20th. Century
    equal all what happened
              since
      the creation of man
You may wonder what had WW 1 to do with
            Neurosurgery?
Or what’s its connection with the
Paris Peace Conference 0n 27.5.1919?
Egas Moniz
                                  (1874 – 1955)
                               Prof. Of Neurology
                                     , Lisbon
                               Foreign Minister of
                                    Portugal
                               Nobel Prize Winner
                                       1949




He was the one who invented cerebral angiography and
 performed the first lobotomy on psychiatric patients
ANGIOGRAPHY remained the mainstay of diagnostic tools for
most neurosurgical problems until CT was invented, and is only
reserved for vascular problems now
Angiography
 is used in
 addition in
 Cardiology
  Vascular
  Surgery
  Kidney
  Surgery
   Tumor
  Surgery
A simple procedure which may save lives


A catheter to inject the dye          A digital X-ray machine




                          SELDINGER
Without angiography

 Many would have           Many would have
  died following cardiac     died following clotting
  angina                     of their veins
 Many would have           Many would have
  died following             died following kidney
  cerebral bleeding          artery disease
 Many would have
  suffered limb
  amputation
You wonder what had The Beatles to do with
            Neurosurgery?
Or what’s their connection to this
            Hospital?
Electric and Musical Industries (EMI) Ltd
           Company, Hayes, UK
                             Atkinson Morley’s
  The Beatles                      Hospital
 The money                Served as the site
  earned by the             were G. Hounsfield
  company from              and J. Ambrose
 proceedings of             worked to invent the
 the sale of the            first Computerized
 Beatles’ records           Axial Tomography
 under the music            machine called EMI to
 label EMI, were            take images of the
                            br ai n
 collected
I nvent or s of t he C scan i n 1973
                        T
       (Fi r st cal l ed EM scan)
                           I
    James Ambrose        Godfrey Hounsfield
C put er i zed t om aphy (C
 om                ogr     T)

    Allowed doctors to:              Helped doctors to:
 See inside the body for the    Do minimally invasive
  first time                      procedures by guiding
 Follow the progress of          needles inside body organs
  tumors inside the body         Direct radiotherapy at
 Screen people for disease       small targets in body
                                  organs
I bet when you visited the Egyptian
Museum, you did not think it had any
    connection to Neurosurgery
The Edwin Smith Papyrus

      Old Egyptians                Old Egyptians
 Evacuated the brain         Did simple surgeries on
  substance from the dead      the skull like treatment of
  people in the process of     wounds and fractures
  mummification through a      and did trepanation
  hole in the base of the      (making holes) in the
  skull                        skull to remove blood
And you still do not know what had the old Egyptians
               to do with Neurosurgery?
In 1906 Harvey Cushing performed the 1st.
trans sphenoidal surgery for pituitary tumors
   The Pituitary Gland        The instrument
Trans sphenoidal surgery

Using the
same old
route.
Quick surgery
Short stay in
hospital
Very few
complications
You never thought that there could be any
relation between a sheep and an egg
Louise Brown The 1st test tube baby (born 25
July 1978)
                         Born in Oldham, UK
                         Not a test tube baby
                         But a Petri dish baby
                         Patrick Steptoe and
                          Robert Edwards were
                          the doctors to do this.
                          Now IVF is practiced
                          daily.
Dolly the sheep (5 July 1996 – 14 February 2003)


  Ian Wilmut, Keith
   Campbell and
   colleagues at
   the Roslin Institute
   in
   Edinburgh, Scotland
  A cell taken from a
   specific part of the
   body could recreate
   a whole individual.
But then artificial fertilization of eggs (ova) and
manipulating cell from animals lead to

            IVF                          CLONING
 Fertilizing human ova in       Reproducing tissues and
  the lab and then                animals lead to the
  implanting them in the          improvement of breeds
  womb solved the                 and preservation of
  problems of childless           endangered species
  couples
 1% of all pregnancies in
  the USA use IVF
Who was from South Africa and was more
famous than Mandela then?
  In Cape        Dead and Al i ve
Town, SOUTH
  AFRICA


Denise Darvell
   died on
  3.12.1967


   Louis
Washkansky
was dying on
 3.12.1967
On that same night of (3.12.1967) Christian Bernard
became the most famous surgeon in the world

      The Surgeon                    What for?

                              He took the heart of the
                               dead Denise and
                               transplanted it into the
                               dying Louis.
                              Louis lived 18 days and
                               cardiac transplantation
                               was born
Oh..what a feeling…

IN 1985, THIS SURGEON   JORDAN BECAME


                        THE 6TH COUNTRY
                         IN THE WORLD
                          TO PERFORM
                             HEART
                           TRANSPLANT
Since then..man invented artificial hearts


    In 1982 the Jarvik 7 artificial heart was made
and implanted them inside patients

Dr. William DeVries in 1982   Implanted the Jarvik 7 heart
Better health..more people..less resources


    BETTER HEALTH              BETTER HEALTH
 Better maternal health    Better supply of clean
 Safer deliveries           water
 Immunization              Better sewage disposal
 Better child health       Better education
Regulating population growth

   Margaret Sanger       1952-1960
                      Financed research
                       by 150.000 $ from
                        her own money
                         resulting in the
                        manufacturing of
                            the Oral
                       Contraceptive Pill
                             (OCP)
Regulating population growth

   Howard Tatum             1968
                      Worked on earlier
                      designs of the intra
                      uterine device (IUD)
                       to manufacture the
                      Copper-T (Tatum-T)
                         device which is
                      being used till today
WE COULD GO ON FOR HOURS……




       THANK YOU

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Milestones in Medicine

  • 1. MILESTONES IN MEDICINE WALID MAANI THE UNIVERSITY OF JORDAN
  • 2. Milestones In Medicine? Difficult to choose. Advances in 20th. Century equal all what happened since the creation of man
  • 3. You may wonder what had WW 1 to do with Neurosurgery?
  • 4. Or what’s its connection with the Paris Peace Conference 0n 27.5.1919?
  • 5. Egas Moniz (1874 – 1955) Prof. Of Neurology , Lisbon Foreign Minister of Portugal Nobel Prize Winner 1949 He was the one who invented cerebral angiography and performed the first lobotomy on psychiatric patients
  • 6. ANGIOGRAPHY remained the mainstay of diagnostic tools for most neurosurgical problems until CT was invented, and is only reserved for vascular problems now Angiography is used in addition in Cardiology Vascular Surgery Kidney Surgery Tumor Surgery
  • 7. A simple procedure which may save lives A catheter to inject the dye A digital X-ray machine SELDINGER
  • 8. Without angiography  Many would have  Many would have died following cardiac died following clotting angina of their veins  Many would have  Many would have died following died following kidney cerebral bleeding artery disease  Many would have suffered limb amputation
  • 9. You wonder what had The Beatles to do with Neurosurgery?
  • 10. Or what’s their connection to this Hospital?
  • 11. Electric and Musical Industries (EMI) Ltd Company, Hayes, UK Atkinson Morley’s The Beatles Hospital  The money  Served as the site earned by the were G. Hounsfield company from and J. Ambrose proceedings of worked to invent the the sale of the first Computerized Beatles’ records Axial Tomography under the music machine called EMI to label EMI, were take images of the br ai n collected
  • 12. I nvent or s of t he C scan i n 1973 T (Fi r st cal l ed EM scan) I James Ambrose Godfrey Hounsfield
  • 13. C put er i zed t om aphy (C om ogr T) Allowed doctors to: Helped doctors to:  See inside the body for the  Do minimally invasive first time procedures by guiding  Follow the progress of needles inside body organs tumors inside the body  Direct radiotherapy at  Screen people for disease small targets in body organs
  • 14. I bet when you visited the Egyptian Museum, you did not think it had any connection to Neurosurgery
  • 15. The Edwin Smith Papyrus Old Egyptians Old Egyptians  Evacuated the brain  Did simple surgeries on substance from the dead the skull like treatment of people in the process of wounds and fractures mummification through a and did trepanation hole in the base of the (making holes) in the skull skull to remove blood
  • 16. And you still do not know what had the old Egyptians to do with Neurosurgery?
  • 17. In 1906 Harvey Cushing performed the 1st. trans sphenoidal surgery for pituitary tumors The Pituitary Gland The instrument
  • 18. Trans sphenoidal surgery Using the same old route. Quick surgery Short stay in hospital Very few complications
  • 19. You never thought that there could be any relation between a sheep and an egg
  • 20. Louise Brown The 1st test tube baby (born 25 July 1978)  Born in Oldham, UK  Not a test tube baby  But a Petri dish baby  Patrick Steptoe and Robert Edwards were the doctors to do this. Now IVF is practiced daily.
  • 21. Dolly the sheep (5 July 1996 – 14 February 2003)  Ian Wilmut, Keith Campbell and colleagues at the Roslin Institute in Edinburgh, Scotland  A cell taken from a specific part of the body could recreate a whole individual.
  • 22. But then artificial fertilization of eggs (ova) and manipulating cell from animals lead to IVF CLONING  Fertilizing human ova in  Reproducing tissues and the lab and then animals lead to the implanting them in the improvement of breeds womb solved the and preservation of problems of childless endangered species couples  1% of all pregnancies in the USA use IVF
  • 23. Who was from South Africa and was more famous than Mandela then? In Cape Dead and Al i ve Town, SOUTH AFRICA Denise Darvell died on 3.12.1967 Louis Washkansky was dying on 3.12.1967
  • 24. On that same night of (3.12.1967) Christian Bernard became the most famous surgeon in the world The Surgeon What for?  He took the heart of the dead Denise and transplanted it into the dying Louis.  Louis lived 18 days and cardiac transplantation was born
  • 25. Oh..what a feeling… IN 1985, THIS SURGEON JORDAN BECAME THE 6TH COUNTRY IN THE WORLD TO PERFORM HEART TRANSPLANT
  • 26. Since then..man invented artificial hearts In 1982 the Jarvik 7 artificial heart was made
  • 27. and implanted them inside patients Dr. William DeVries in 1982 Implanted the Jarvik 7 heart
  • 28. Better health..more people..less resources BETTER HEALTH BETTER HEALTH  Better maternal health  Better supply of clean  Safer deliveries water  Immunization  Better sewage disposal  Better child health  Better education
  • 29. Regulating population growth Margaret Sanger 1952-1960  Financed research by 150.000 $ from her own money resulting in the manufacturing of the Oral Contraceptive Pill (OCP)
  • 30. Regulating population growth Howard Tatum 1968  Worked on earlier designs of the intra uterine device (IUD) to manufacture the Copper-T (Tatum-T) device which is being used till today
  • 31. WE COULD GO ON FOR HOURS…… THANK YOU