Dr. Gayathiri Ganesan Ram provides an overview of surrogacy in 3 sentences or less:
Surrogacy involves a woman carrying and delivering a child for another couple, and can be done through natural or IVF means using the genetic parents' gametes. It is an option for women unable to carry a pregnancy themselves due to medical reasons. The document outlines the counseling, treatment, and legal considerations involved in surrogacy arrangements in India.
Surrogacy Regulation Act 2021 has been notified in the Gazette on 25th December 2021 and there are important implications for all who practice surrogacy in India both for patients and clinics and ART Banks.
In this ppt, surrogacy is defiend and its types on the basis of method and another types on the basis of money and their differences as well. Regulation bill 2016 and its features has been also discussed.
Uterus Transplantation Utx (obstetric and gynecology) D.A.B.M
Is the surgical procedure whereby a healthy uterus is transplanted into an organism of which the uterus is absent or diseased.
As part of normal mammalian sexual reproduction, a diseased or absent uterus does not allow normal embryonic implantation, effectively rendering the female infertile.
This phenomenon is known as Absolute Uterine Factor Infertility (AUFI).
Uterine transplant is a potential treatment for this form of infertility.
Uterus is a dynamic, complex organ. It is hugely blood-flow dependent.
More than 116,000 Number of men, women and children on the national transplant waiting list as of August 2017.
33,611 transplants were performed in 2016.
20 people die each day waiting for a transplant.
every 10 minutes another person is added to the waiting list.
A Surrogate is a process of arrangement for women to carry and give birth to a child who will be raised by others. For more info visit http://www.growinggenerations.com
Surrogacy Regulation Act 2021 has been notified in the Gazette on 25th December 2021 and there are important implications for all who practice surrogacy in India both for patients and clinics and ART Banks.
In this ppt, surrogacy is defiend and its types on the basis of method and another types on the basis of money and their differences as well. Regulation bill 2016 and its features has been also discussed.
Uterus Transplantation Utx (obstetric and gynecology) D.A.B.M
Is the surgical procedure whereby a healthy uterus is transplanted into an organism of which the uterus is absent or diseased.
As part of normal mammalian sexual reproduction, a diseased or absent uterus does not allow normal embryonic implantation, effectively rendering the female infertile.
This phenomenon is known as Absolute Uterine Factor Infertility (AUFI).
Uterine transplant is a potential treatment for this form of infertility.
Uterus is a dynamic, complex organ. It is hugely blood-flow dependent.
More than 116,000 Number of men, women and children on the national transplant waiting list as of August 2017.
33,611 transplants were performed in 2016.
20 people die each day waiting for a transplant.
every 10 minutes another person is added to the waiting list.
A Surrogate is a process of arrangement for women to carry and give birth to a child who will be raised by others. For more info visit http://www.growinggenerations.com
interest in stem cells is raising in different field of medicine. The question is : is it successful in Gynecology or it is still too early to say that. The present talk may help to explore this .
MEDICO LEGAL ISSUES In Infertility & IVF DR. SHARDA JAIN Dr. Jyoti Agarwal ...Lifecare Centre
MEDICO LEGAL ISSUES In Infertility & IVF DR. SHARDA JAIN Dr. Jyoti Agarwal Dr. Jyoti Bhaskar
HISTORY of IVF
THE WORLD FIRST IVF BABY..LOUISE BROWN 25/7/1978
WORLD 2nd but INDIA,s first undocumented IVF BABY..KANUPRIYA [DURGA]…was born
67 days later on 3/10/1978 through effort of
DR SUBHAS MUKHERJEE****Mainly went unnoticed
BABY HARSHA 6/8/1986 …
BOMBAY KEM HOSPITAL + ICMR Effort.
Invited Lecture delivered by Dr Sujoy Dasgupta in the Annual Conference of ISAR (Indian Society of Assisted Reproduction) held at Kolkata in November, 2019
Role of Stem Cells in Obstetrics and Gynecology PracticeAsha Jain
Role of Stem Cells in Obstetrics and Gynecology Practice
Talk delivered at 4th Biennial International ISCSGCON 2021
on Febuary 13,2021 by Dr. Asha Jain
The Assisted Reproductive Techniques - ART (IVF, IUI, ZIFT, GIFT, ICSI etc.)Muhammad Anas Shamsi
Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg and a man's sperm. It works by removing eggs from a woman's body. The eggs are then mixed with sperm to make embryos. The embryos are then put back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ART.
The HFEA is the independent regulator for IVF treatment and human embryo research and came into effect on 1 August 1991. The 1990 Act ensured the regulation, through licensing, of:
the creation of human embryos outside the body and their use in treatment and research
the use of donated gametes and embryos
the storage of gametes and embryos.
PGD is a state-of-the-art procedure used in conjunction with In Vitro Fertilization (IVF) in which the embryo is tested for certain conditions prior to being placed in the womb of the woman.
Selection of an embryo from a large number of embryos and then placing it to the uterus is known as selective embryo transfer. This fertility preservation process is usually done after the process of IVF cycle and cancels the risks of spontaneous transfer of multiple embryos. Have a look at the detailed description of elective single embryo transfer in the following ppt.
Surrogacy in India is an attractive option for couples who wish to have their names on the birth certificate; want to have a professional or limited relationship with their surrogate, but have the benefit of excellent healthcare. Surrogates in India have no parental rights and cannot change their mind about handing over a child to the intended parents.
interest in stem cells is raising in different field of medicine. The question is : is it successful in Gynecology or it is still too early to say that. The present talk may help to explore this .
MEDICO LEGAL ISSUES In Infertility & IVF DR. SHARDA JAIN Dr. Jyoti Agarwal ...Lifecare Centre
MEDICO LEGAL ISSUES In Infertility & IVF DR. SHARDA JAIN Dr. Jyoti Agarwal Dr. Jyoti Bhaskar
HISTORY of IVF
THE WORLD FIRST IVF BABY..LOUISE BROWN 25/7/1978
WORLD 2nd but INDIA,s first undocumented IVF BABY..KANUPRIYA [DURGA]…was born
67 days later on 3/10/1978 through effort of
DR SUBHAS MUKHERJEE****Mainly went unnoticed
BABY HARSHA 6/8/1986 …
BOMBAY KEM HOSPITAL + ICMR Effort.
Invited Lecture delivered by Dr Sujoy Dasgupta in the Annual Conference of ISAR (Indian Society of Assisted Reproduction) held at Kolkata in November, 2019
Role of Stem Cells in Obstetrics and Gynecology PracticeAsha Jain
Role of Stem Cells in Obstetrics and Gynecology Practice
Talk delivered at 4th Biennial International ISCSGCON 2021
on Febuary 13,2021 by Dr. Asha Jain
The Assisted Reproductive Techniques - ART (IVF, IUI, ZIFT, GIFT, ICSI etc.)Muhammad Anas Shamsi
Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg and a man's sperm. It works by removing eggs from a woman's body. The eggs are then mixed with sperm to make embryos. The embryos are then put back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ART.
The HFEA is the independent regulator for IVF treatment and human embryo research and came into effect on 1 August 1991. The 1990 Act ensured the regulation, through licensing, of:
the creation of human embryos outside the body and their use in treatment and research
the use of donated gametes and embryos
the storage of gametes and embryos.
PGD is a state-of-the-art procedure used in conjunction with In Vitro Fertilization (IVF) in which the embryo is tested for certain conditions prior to being placed in the womb of the woman.
Selection of an embryo from a large number of embryos and then placing it to the uterus is known as selective embryo transfer. This fertility preservation process is usually done after the process of IVF cycle and cancels the risks of spontaneous transfer of multiple embryos. Have a look at the detailed description of elective single embryo transfer in the following ppt.
Surrogacy in India is an attractive option for couples who wish to have their names on the birth certificate; want to have a professional or limited relationship with their surrogate, but have the benefit of excellent healthcare. Surrogates in India have no parental rights and cannot change their mind about handing over a child to the intended parents.
2.1 DEFINITION OF INFERTILITY :
Infertility is defined as a failure to conceive within one or more year of regular unprotected coitus.
2.2 TYPES OF INFETILITY:
1. PRIMARY INFERTILITY:
SECONDARY INFERTILITY
2.3 CAUSES OF INFERTILITY :
• MALE FACTORS :
DEFECTIVE SPERMATOGENESIS
SECONDARY INFERTILITY
2.3 CAUSES OF INFERTILITY :
• MALE FACTORS :
DEFECTIVE SPERMATOGENESIS
Infection
Gonadotropin suppression
Endocrine factors
Immunological factors
Tubal and peritoneal factors
UTERINE FACTORS CERVICAL FACTORS
VAGINAL FACTORS
COMBINED FACTORS
DIAGNOSTIC PROCEDURES
FOR FEMALE
HISTORY
EXAMINATIONS
DIAGNOSTIC EVALUATION:
1. CERVICAL MUCUS STUDY
2. HORMONAL ESTIMATION
3. ENDOMETRIAL BIOPSY
4. SONOGRAPHY
5. LAPROSCOPY
6. INSUFFLATION TEST (Rubin’s test)
2.5 RECENT ADVANCEMENT IN INFERTILITY MANAGEMENT :
ASSISTED REPRODUCTIVE TECHNIQUES (ART)
“ASSISTED REPRODUCTIVE TECHNIQUES INVOLVING DIRECT RETRIEVAL OF OOCYTE FROM OVARY, MANIPULATION OF GAMETS AND EMBROYOS OUTSIDE BODY FOR PURPOSE OF ESTABLISHING PREGNANCY”.
TYPES OF ART :
1. IUI (Intrauterine insemination)
2. IVF-ET(In vitro fertilization & embryo transfer)
3. ZIFT(Zygote intra fallopian transfer)
4. ICSI (Intra cytoplasmic sperm injection) (TESA, PESA, MESA)
5. EMBRYO OR OOCYTE DONATION
6. GESTATIONAL CARRIER
7. SURROGACY
2.6 ROLE OF NURSE IN MANAGEMENT OF
INFERTILITY :
] ASSESSMENT :
- Assessment of the infertile couple is the initial stage of infertility management. The nurse is often the first contact the infertile couple make during their visit for treatment. The nurses role during this stage is to educate the couple about each test or investigation. The nurse plays a vital role in alleviating the fear and anxiety about the various diagnostic procedure.
2] TREATMENT :
- The nurse plays the link between the doctor and the couple and should always be available to the couple for their assistance, guidance and support before, during and after the infertility treatment.
- Numerous ethical issues are associated with infertility treatments and the couple undergoing treatment need appropriate counselling and discussion.
-The goal of the nurse helping the infertile couple is to assist them through the treatment cycle as smoothly as possible.
3] EDUCATION :
- The role of a nurse in educating the patients includes education about the basic male and female anatomy and physiology and how the drugs act on their body, including possible side effects. This may be offered under various setting such as
• Face to face on an individual basis.
• In a group situation,
• Fertility nurses should also educate the couple about the self-administer medications.
• Proper knowledge of administration of these medicines and storage conditions for medications, as well as the possible side affects, should be imparted to the couple undergoing treatment.
4] PSYCHOLOGICAL SUPPORT :
-A couple undergoing infertility treatments are usually under stress due to variety of reasons.
Dr Sujoy Dasgupta moderated a panel in “Milan”, the conference of all of the Obstetric and Gynaecological Societies of West Bengal, held in Kolkata in February, 2022
Raipur IVF Centre offer all range of surrogacy treatment, surrogate mother in India, Raipur because of our high success rates,Become a Surrogate in India
Growing Families is a non-profit organization that provides support to people who are struggling with infertility. We provide egg donation, embryo shipping, and surrogacy to Australian families. If you're an intended parent who wants to have a child and you're unable to conceive, our Growing Families Organization in Australia can help you.
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
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India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
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One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...
Surrogacy by Dr. Gayathiri
1. SURROGACY
Dr. Gayathiri Ganesan Ram
MS(O.G), Fellow in Reproductive Medicine and
Andrology.
Consultant Reproductive Medicine Specialist
ARC Fertility Hospitals
2. INTRODUCTION
• The earliest mention of the term `surrogacy' is
in the Old Testament of the Holy Bible
• The story is told that, because Sarai had been
unable to bear Abraham a child, she
suggested to him that he `go unto my maid
Hagar; it may be that I may obtain by her'.
Abraham did as he was told and, at the age of
90 years, he was able to father a child by
Hagar, and Ishmael was born.
3. • Until the introduction of modern assisted
reproductive techniques, `traditional or partial
surrogacy' was the only means of helping
women who had no uterus or major
abnormalities of the uterus to have children.
4. • The term `surrogate mother' or `surrogate' is
usually applied to the woman who carries and
delivers a child on behalf of another couple.
• Rent – a – womb.
5. • Genetic couple, commissioning couple, intended
parents – the couple who provide the sets of
gametes.
• Surrogate host – The woman receiving the
embryos created from the gametes of the genetic
couple.
• Natural surrogacy, traditional surrogacy,partial
surrogacy – eggs belong to female carrying the
baby, the intended host is inseminated wuth the
semen of the husband of the genetic couple.
6. • Gestational surrogacy, IVF surrogacy – a
treatment by which gametes of the genetic
couple or intended couple in a surrogacy
arrangement are used to produce embryos
and these embryos are transferred to a
woman who agrees to act as a host for these
embryos.
7. • Commercial surrogacy – surrogate is paid over
and above the necessary medical expenses.
• Altruistic surrogacy – surrogate is paid only
the necessary pregnancy related expenses and
at times nothing at all.
8. INDICATIONS
• Women without a uterus but with one or both
ovaries functioning. Women with congenital
absence of uterus, hysterectomy for cancer or
fibroid.
• Women who suffered repeated miscarriage,
failed ivf cycles.
• Severe heart disease where pregnancy is CI
9. COUNSELLING
• The aim is to prepare both couples contemplating
this treatment to consider all the facts and to
look carefully at the implications for them, both
short-term and long-term.
• For the proposed host and her partner, careful
consideration must also be given to the
implications of their proposed action on their
existing children.
10. TREATMENT OF GENETIC MOTHER
• Stimulation with gonadotrophins.
• Oocyte retrieval.
• Embryos are frozen for minimum of 3 months.
• During the last month, host mother is further
counselled, genetic parents have to undergo
HIV test,if negative then go for HRT.
12. QUARANTINE OF HIV STATUS
• Regulations in the UK require that the sperm
of the commissioning or genetic
husband/partner must be `quarantined' for 6
months before being used, or the embryos
created with his sperm must be frozen and
quarantined for 6 months (Human Fertilisation
and Embryology Authority, 2001).
13. • . The genetic husband/partner then has a further
test of his HIV status and the embryos may be
transferred or the sperm thawed and used to
create `fresh' embryos for transfer to the
surrogate host.
• This policy is governed by the rule which states
that sperm used in surrogacy arrangements must
be treated in the same way as donor sperm,
which, by law in the UK, must be frozen and
quarantined for 6 months before it can be used.
14. GENERAL CONSIDERATION
• A child born through surrogacy must be
adopted by the genetic (biological) parents
unless they can establish through genetic
(DNA) fingerprinting (of which the records will
be maintained in the clinic) that the child is
theirs.
15. • Surrogacy by assisted conception should normally
be considered only for patients for whom it
would be physically or medically impossible/
undesirable to carry a baby to term.
• Payments to surrogate mothers should cover all
genuine expenses associated with the pregnancy.
Documentary evidence of the financial
arrangement for surrogacy must be available. The
ART centre should not be involved in this
monetary aspect.
16. • Advertisements regarding surrogacy should not
be made by the ART clinic. The responsibility of
finding a surrogate mother, through
advertisement or otherwise, should rest with the
couple, or a semen bank
• A surrogate mother should not be over 45 years
of age. Before accepting a woman as a possible
surrogate for a particular couple’s child, the ART
clinic must ensure (and put on record) that the
woman satisfies all the testable criteria to go
through a successful full-term pregnancy.
17. • A relative, a known person, as well as a person
unknown to the couple may act as a surrogate
mother for the couple. In the case of a relative
acting as a surrogate, the relative should
belong to the same generation as the women
desiring the surrogate.
• She should not act as surrogate for more than
3 times in her life.
18. • A prospective surrogate mother must be tested for HIV
and shown to be seronegative for this virus just before
embryo transfer.
• She must also provide a written certificate that (a) she
has not had a drug intravenously administered into her
through a shared syringe, (b) she has not undergone
blood transfusion; and (c) she and her husband (to the
best of her/his knowledge) has had no extramarital
relationship in the last six months. (This is to ensure
that the person would not come up with symptoms of
HIV infection during the period of surrogacy.) The
prospective surrogate mother must also declare that
she will not use drugs intravenously, and not undergo
blood transfusion excepting of blood obtained through
a certified blood bank.
19. HIGHLIGHTS OF ICMR GUIDELINES
• The ART clinic shall not play a role in
commercial surrogacy arrangements.
• It entitles the surrogate to receive financial
compensation.
• Close members of the infertile couple can act
as surrogate.
• The birth certificate shall have the name of
the genetic parents.
20. • The surrogate must surrender all parental
rights as regard the child in writing.
• It specifies that surrogacy arrangements are a
viable option only for infertile couples or for
those whose pregnancy can prove to be
hazardous.
• ART clinics has to get approval from
appropriate accreditation authorities. Legally
justified.
21. NOT OPPOSED TO PUBLIC POLICY
• Agreement to give or take child
22. GENETIC LINKAGE
• Mere adoptation does not give a genetic
linkage to child.
• Birth Certificate – name of genetic parents.
23. INDIA ADVANTAGE
• Surrogate has no legal rights over the child.
• Cost factor is much less.
• Financial compensation is allowed to the
surrogate.
• No long waiting lists.
• Birth certificate in the name of the genetic
parents.
• Good results and very efficient IVF treatment.
24. BABY MANJI CASE
• Last summer, a baby girl named Manji was born to an Indian surrogate. These
days, there's nothing too unusual about that: According to The Economist, the
Indian surrogacy market is now worth about half a billion dollars. Surrogates are
typically poor uneducated women from rural villages. Fertility clinics pay them
between $4,500 and $5,000 for carrying a pregnancy, and charge their clients -
many of whom come from outside the country - about twice that.
In this case, the arrangement got sticky not because the surrogate wanted to keep
the baby (a common concern for those hiring a surrogate) but because the
Japanese couple who were the "intended parents" had divorced. The husband still
wanted to raise Manji, but his ex-wife did not.
The father found himself in a catch-22. India requires that a child be legally
adopted before leaving the country, but bars single men from adopting. Manji's
father was denied travel documents for the baby. The situation was widely covered
in Indian and global media, and grew into a legal and diplomatic crisis.
Manji was eventually permitted to leave for Japan, but the debate within India
about surrogacy has continued.