This document provides an overview of cerebellopontine angle tumors. It begins with an introduction and outlines the types, etiology, clinical features, diagnosis, and management of cerebellopontine angle tumors. The most common type is vestibular schwannoma, which accounts for 80-85% of cases. Management options include conservative monitoring, surgery via the translabyrinthine, middle fossa, or retrosigmoid approaches, and radiotherapy using stereotactic radiosurgery. The goals of management are complete tumor removal while preserving cranial nerve function.
Cerebellopontine Angle Tumor can arise from various structures in the CPA. Vestibular schwannoma, also known as acoustic neuroma, is the most common type and arises from the vestibulocochlear nerve. Patients present with hearing loss, tinnitus, and imbalance. MRI is the preferred imaging method and shows a well-defined enhancing mass. Treatment options include observation, surgery to remove the tumor, and stereotactic radiosurgery.
This document discusses different types of intradural spinal tumors, including their presentation, diagnosis, and management. The main types discussed are:
- Intradural extramedullary tumors (40%) like meningiomas, schwannomas, and neurofibromas.
- Intramedullary spinal cord tumors (5%) such as astrocytomas and ependymomas.
- Meningiomas are the most common, often occurring in middle-aged women. Diagnosis is typically made using MRI and surgical excision is the main treatment. Prognosis depends on tumor type, with complete resection generally resulting in low recurrence rates.
The document discusses the systematic approach to characterizing brain tumors on MRI. It describes three main steps: detection, localization, and characterization. Localization involves determining if a tumor is intra-axial or extra-axial based on signs like a CSF cleft between the brain and lesion. Characterization includes assessing features like enhancement pattern, border definition, and presence of necrosis to differentiate tumor types such as meningioma, schwannoma, glioma, and metastasis. The references provided give further information on diagnostic criteria.
General features & management of Common neck lumps are described in this presentation. which are important for Medical students and ENT doctors.
Topics discussed in this presentation are
Cystic hygroma
Hemangioma
Branchial cyst
Thyroglossal cyst
Lipoma
Sebaceous cyst
Cervical lymphadenopathy
Tuberculosis
Carotid body tumor
Preauricular Cyst/Sinus
Lymphoma
Intraventricular mass (Radiology) of a child {A CASE}Dr.Santosh Atreya
An intraventricular mass was found in a 5-year-old child. The main differential diagnoses included choroid plexus carcinoma, central neurocytoma, primitive neuroectodermal tumor, and atypical teratoid rhabdoid tumor. Imaging findings like location in the ventricle, enhancement pattern, and presence of calcification or cysts can help narrow the diagnosis, as the masses have overlapping characteristics. An accurate diagnosis is important to guide surgical planning and determine appropriate post-operative treatment.
This document provides an overview of common pediatric brain tumors located in the posterior fossa (infratentorial region). It discusses the most frequently used MRI sequences for evaluating these tumors and provides clinical and imaging features of the most common tumor types, including medulloblastoma, ependymoma, pilocytic astrocytoma, and brainstem glioma. Differential diagnoses are also reviewed. Key sequences discussed are T1WI, T2WI, FLAIR, DWI, and post-contrast T1WI. Common features and imaging findings are highlighted for each tumor type in 1-3 sentences.
A 40-year-old female presented with progressive vision impairment and headaches. MRI showed a well-defined suprasellar mass compressing surrounding structures and enhancing with a dural tail. Radiological findings were consistent with a suprasellar meningioma extending along the planum sphenoidale and dorsum sellae. Meningiomas typically originate from arachnoid cells, are most common in the supratentorial compartment, and demonstrate avid enhancement with a dural tail on MRI. Surgical resection aims to remove the tumor and involved dura.
This document provides an overview of cerebellopontine angle tumors. It begins with an introduction and outlines the types, etiology, clinical features, diagnosis, and management of cerebellopontine angle tumors. The most common type is vestibular schwannoma, which accounts for 80-85% of cases. Management options include conservative monitoring, surgery via the translabyrinthine, middle fossa, or retrosigmoid approaches, and radiotherapy using stereotactic radiosurgery. The goals of management are complete tumor removal while preserving cranial nerve function.
Cerebellopontine Angle Tumor can arise from various structures in the CPA. Vestibular schwannoma, also known as acoustic neuroma, is the most common type and arises from the vestibulocochlear nerve. Patients present with hearing loss, tinnitus, and imbalance. MRI is the preferred imaging method and shows a well-defined enhancing mass. Treatment options include observation, surgery to remove the tumor, and stereotactic radiosurgery.
This document discusses different types of intradural spinal tumors, including their presentation, diagnosis, and management. The main types discussed are:
- Intradural extramedullary tumors (40%) like meningiomas, schwannomas, and neurofibromas.
- Intramedullary spinal cord tumors (5%) such as astrocytomas and ependymomas.
- Meningiomas are the most common, often occurring in middle-aged women. Diagnosis is typically made using MRI and surgical excision is the main treatment. Prognosis depends on tumor type, with complete resection generally resulting in low recurrence rates.
The document discusses the systematic approach to characterizing brain tumors on MRI. It describes three main steps: detection, localization, and characterization. Localization involves determining if a tumor is intra-axial or extra-axial based on signs like a CSF cleft between the brain and lesion. Characterization includes assessing features like enhancement pattern, border definition, and presence of necrosis to differentiate tumor types such as meningioma, schwannoma, glioma, and metastasis. The references provided give further information on diagnostic criteria.
General features & management of Common neck lumps are described in this presentation. which are important for Medical students and ENT doctors.
Topics discussed in this presentation are
Cystic hygroma
Hemangioma
Branchial cyst
Thyroglossal cyst
Lipoma
Sebaceous cyst
Cervical lymphadenopathy
Tuberculosis
Carotid body tumor
Preauricular Cyst/Sinus
Lymphoma
Intraventricular mass (Radiology) of a child {A CASE}Dr.Santosh Atreya
An intraventricular mass was found in a 5-year-old child. The main differential diagnoses included choroid plexus carcinoma, central neurocytoma, primitive neuroectodermal tumor, and atypical teratoid rhabdoid tumor. Imaging findings like location in the ventricle, enhancement pattern, and presence of calcification or cysts can help narrow the diagnosis, as the masses have overlapping characteristics. An accurate diagnosis is important to guide surgical planning and determine appropriate post-operative treatment.
This document provides an overview of common pediatric brain tumors located in the posterior fossa (infratentorial region). It discusses the most frequently used MRI sequences for evaluating these tumors and provides clinical and imaging features of the most common tumor types, including medulloblastoma, ependymoma, pilocytic astrocytoma, and brainstem glioma. Differential diagnoses are also reviewed. Key sequences discussed are T1WI, T2WI, FLAIR, DWI, and post-contrast T1WI. Common features and imaging findings are highlighted for each tumor type in 1-3 sentences.
A 40-year-old female presented with progressive vision impairment and headaches. MRI showed a well-defined suprasellar mass compressing surrounding structures and enhancing with a dural tail. Radiological findings were consistent with a suprasellar meningioma extending along the planum sphenoidale and dorsum sellae. Meningiomas typically originate from arachnoid cells, are most common in the supratentorial compartment, and demonstrate avid enhancement with a dural tail on MRI. Surgical resection aims to remove the tumor and involved dura.
Meningiomas are tumors that arise from meningothelial cells of the arachnoid mater. They constitute 20% of all primary intracranial tumors with an incidence of 2.3 per 100,000 people. On pathology, meningiomas are graded based on their malignant potential from Grade I to Grade III. Grade I meningiomas include meningothelial, fibrous, transitional and psammomatous subtypes. Grade II are atypical meningiomas and Grade III include anaplastic, papillary and rhabdoid subtypes. Diagnosis is typically made based on imaging features seen on CT and MRI scans. Treatment involves surgical resection although radiation and medical management may
This document provides an outline on sinonasal tumours. It discusses the relevant anatomy, epidemiology, classification, clinical features, investigations, staging, treatment and complications of sinonasal tumours. It notes that sinonasal tumours comprise a diverse group of benign and malignant neoplasms that often present non-specifically, leading to delays in diagnosis and management. The document outlines the different tumour types, their characteristics, staging systems used and multidisciplinary treatment approaches involving surgery, radiotherapy and chemotherapy. Early detection and management is emphasized for improving patient outcomes.
CNS RADIOLOGY FOR RADIATION ONCOLOGISTSKanhu Charan
This document provides an overview of radiology for brain and spine imaging for radiation oncologists. It discusses various imaging modalities including CT, MRI, nuclear imaging and angiography. It describes key anatomical structures of the brain such as the meninges, ventricles, sulci and gyri, lobes, basal ganglia and cerebellum. Different MRI sequences are outlined including T1, T2, FLAIR, DWI and perfusion. Spine imaging including sequences for T1, T2, STIR and post-contrast are also reviewed. Important considerations for planning MRI such as field of view and disease-specific sequences are highlighted.
This document discusses the management of meningiomas. It covers the classification, diagnosis and treatment of grades I, II and III meningiomas. For grade I meningiomas, observation or surgery is typically recommended. Adjuvant radiation may be used after subtotal resection. For grade II meningiomas, maximal safe resection followed by radiation is usually recommended. For grade III meningiomas, maximal resection combined with high-dose radiation or chemoradiation is the standard approach due to their aggressive nature.
This document discusses head and neck paragangliomas (HNPs), which are rare neoplasms arising from paraganglionic tissue located in the head and neck region. It defines paragangliomas and paraganglia, and describes the most common locations and characteristics of HNPs. The document also covers the histopathology, evaluation, and management of HNPs, noting that the majority are benign but locally invasive tumors that can be treated with surgery or radiotherapy depending on their size and location.
This presenation includes anatomy and pathology of intraconal conal and extraconal orbital pathology. this presenation dealsimaging feature of different pathology. Thanks.
In this presentation, i have explained different modalities available for radiological evaluation of cns tumors. How to approach to a radiographic image and how to approach to a patient of cns tumors radiologically.
The document provides an overview of MRI principles for intracranial lesions. It discusses the basic components and physics of MRI, important sequences like T1WI, T2WI, FLAIR and DWI/ADC for evaluating lesions. It covers indications for brain MRI and principles of imaging and reporting findings. Examples of various congenital and acquired intracranial lesions are presented with MRI images and findings, including tumors, infections, and vascular abnormalities.
This document discusses mediastinal tumors, including:
1. It provides an overview of the anatomy of the mediastinum and introduces the wide variety of mediastinal masses that can be benign or malignant, primary or secondary.
2. The clinical presentation of mediastinal masses is discussed, noting that most are asymptomatic but can cause symptoms depending on location, nature, and associated conditions.
3. Diagnostic workups including imaging modalities like CT, MRI, and ultrasound are outlined to characterize masses based on features. Biopsy approaches are also covered.
This document provides information on intracranial tumours, including:
1. Gliomas are the most common primary brain tumour, with astrocytomas being the most common type. They are graded based on malignancy from Grade I to IV.
2. Meningiomas arise from the arachnoids and attach to the dura, comprising 18% of primary brain tumours. They are usually benign but can invade bone.
3. Clinical features of brain tumours include headaches, seizures, neurological deficits depending on the tumour location. Investigations include imaging scans and biopsies while treatments involve surgery, radiation, chemotherapy.
This document discusses intracranial space occupying lesions, including their definition, types, clinical presentations, diagnosis, and treatment. It defines these lesions as those that expand in volume to displace normal neural structures and may increase intracranial pressure. It then describes the main types of lesions such as primary and metastatic brain tumors, traumatic injuries like hematomas, and infectious or inflammatory causes. The clinical presentations, diagnosis using imaging and other tests, and treatment approaches are outlined for each of the major lesion types. Surgical resection and other procedures are discussed as primary treatment methods depending on the specific lesion.
Thyroid malignancies are the most common endocrine malignancies. The annual incidence is 3.7 per 100,000 people with a 3:1 female to male ratio. The main types are papillary carcinoma (60% of cases), follicular carcinoma (17%), anaplastic carcinoma (13%), and medullary carcinoma (6%). Risk factors include a history of radiation exposure, family history, and certain genetic syndromes. Presentation varies from asymptomatic thyroid nodules to symptoms of compression. Treatment depends on the type and stage of cancer, and may include surgery, radioactive iodine therapy, chemotherapy, and external beam radiation. Prognosis ranges from generally good for differentiated cancers to very poor for anap
Meningioma is a type of tumor that arises from the meninges, the membranes surrounding the brain and spinal cord. It is the most common non-cancerous brain tumor, accounting for 20% of all primary brain tumors. The standard treatment is surgical resection if the tumor is symptomatic or growing in size. For inoperable or recurrent tumors, radiation therapy and medical therapies may be options, though medical therapies have limited effectiveness. The prognosis depends on the tumor grade, with lower grade tumors having better outcomes.
This document provides information about acoustic neuromas (vestibular schwannomas). It defines acoustic neuromas as benign tumors of vestibular nerve schwann cells that arise from the schwann cells within the internal auditory canal. The document discusses the pathogenesis, clinical presentation in different stages, diagnostic evaluations including audiological and radiological tests, differential diagnosis, and treatment options including surgery, observation, and radiotherapy.
This document provides a summary of imaging features of lesions in the anterior skull base region, including sinonasal neoplasms such as squamous cell carcinoma, adenocarcinoma, esthesioneuroblastoma, malignant melanoma, and lymphoma. Key imaging findings discussed include tumor appearance on CT and MRI, characteristics of bone and soft tissue involvement, and distinguishing features between lesion types. Imaging plays an important role in diagnosis and surgical planning for anterior skull base pathology.
General Basic knowledge of Brain tumour explained in brief of classification, pathogenesis, clinical features, CT, MRI, management, Radiotherapy. Best for MBBS and PG preparation student.
This document provides an overview of parapharyngeal space tumors including:
- Anatomy and divisions of the parapharyngeal space
- Common tumor types including salivary gland tumors, neurogenic tumors, and others
- Evaluation with imaging such as CT and MRI
- Surgical approaches including transoral, cervical, and infratemporal fossa approaches
- Specific details on paragangliomas, including carotid body and jugulotympanic tumors
This document discusses brain tumors, including their classification, pathophysiology, clinical manifestations, diagnosis, and treatment. Brain tumors are classified based on their location and cell type, with the most common being gliomas that infiltrate brain tissue. Symptoms vary depending on the tumor location but can include headaches, vomiting, visual issues, seizures, and neurological deficits. Diagnosis involves imaging tests like CT and MRI scans along with possible biopsy. Treatment involves surgical resection when possible along with chemotherapy, radiation therapy, and corticosteroids. Nursing focuses on managing symptoms and self-care deficits caused by neurological impairment or treatment side effects like nutritional issues.
Meningiomas are tumors that arise from meningothelial cells of the arachnoid mater. They constitute 20% of all primary intracranial tumors with an incidence of 2.3 per 100,000 people. On pathology, meningiomas are graded based on their malignant potential from Grade I to Grade III. Grade I meningiomas include meningothelial, fibrous, transitional and psammomatous subtypes. Grade II are atypical meningiomas and Grade III include anaplastic, papillary and rhabdoid subtypes. Diagnosis is typically made based on imaging features seen on CT and MRI scans. Treatment involves surgical resection although radiation and medical management may
This document provides an outline on sinonasal tumours. It discusses the relevant anatomy, epidemiology, classification, clinical features, investigations, staging, treatment and complications of sinonasal tumours. It notes that sinonasal tumours comprise a diverse group of benign and malignant neoplasms that often present non-specifically, leading to delays in diagnosis and management. The document outlines the different tumour types, their characteristics, staging systems used and multidisciplinary treatment approaches involving surgery, radiotherapy and chemotherapy. Early detection and management is emphasized for improving patient outcomes.
CNS RADIOLOGY FOR RADIATION ONCOLOGISTSKanhu Charan
This document provides an overview of radiology for brain and spine imaging for radiation oncologists. It discusses various imaging modalities including CT, MRI, nuclear imaging and angiography. It describes key anatomical structures of the brain such as the meninges, ventricles, sulci and gyri, lobes, basal ganglia and cerebellum. Different MRI sequences are outlined including T1, T2, FLAIR, DWI and perfusion. Spine imaging including sequences for T1, T2, STIR and post-contrast are also reviewed. Important considerations for planning MRI such as field of view and disease-specific sequences are highlighted.
This document discusses the management of meningiomas. It covers the classification, diagnosis and treatment of grades I, II and III meningiomas. For grade I meningiomas, observation or surgery is typically recommended. Adjuvant radiation may be used after subtotal resection. For grade II meningiomas, maximal safe resection followed by radiation is usually recommended. For grade III meningiomas, maximal resection combined with high-dose radiation or chemoradiation is the standard approach due to their aggressive nature.
This document discusses head and neck paragangliomas (HNPs), which are rare neoplasms arising from paraganglionic tissue located in the head and neck region. It defines paragangliomas and paraganglia, and describes the most common locations and characteristics of HNPs. The document also covers the histopathology, evaluation, and management of HNPs, noting that the majority are benign but locally invasive tumors that can be treated with surgery or radiotherapy depending on their size and location.
This presenation includes anatomy and pathology of intraconal conal and extraconal orbital pathology. this presenation dealsimaging feature of different pathology. Thanks.
In this presentation, i have explained different modalities available for radiological evaluation of cns tumors. How to approach to a radiographic image and how to approach to a patient of cns tumors radiologically.
The document provides an overview of MRI principles for intracranial lesions. It discusses the basic components and physics of MRI, important sequences like T1WI, T2WI, FLAIR and DWI/ADC for evaluating lesions. It covers indications for brain MRI and principles of imaging and reporting findings. Examples of various congenital and acquired intracranial lesions are presented with MRI images and findings, including tumors, infections, and vascular abnormalities.
This document discusses mediastinal tumors, including:
1. It provides an overview of the anatomy of the mediastinum and introduces the wide variety of mediastinal masses that can be benign or malignant, primary or secondary.
2. The clinical presentation of mediastinal masses is discussed, noting that most are asymptomatic but can cause symptoms depending on location, nature, and associated conditions.
3. Diagnostic workups including imaging modalities like CT, MRI, and ultrasound are outlined to characterize masses based on features. Biopsy approaches are also covered.
This document provides information on intracranial tumours, including:
1. Gliomas are the most common primary brain tumour, with astrocytomas being the most common type. They are graded based on malignancy from Grade I to IV.
2. Meningiomas arise from the arachnoids and attach to the dura, comprising 18% of primary brain tumours. They are usually benign but can invade bone.
3. Clinical features of brain tumours include headaches, seizures, neurological deficits depending on the tumour location. Investigations include imaging scans and biopsies while treatments involve surgery, radiation, chemotherapy.
This document discusses intracranial space occupying lesions, including their definition, types, clinical presentations, diagnosis, and treatment. It defines these lesions as those that expand in volume to displace normal neural structures and may increase intracranial pressure. It then describes the main types of lesions such as primary and metastatic brain tumors, traumatic injuries like hematomas, and infectious or inflammatory causes. The clinical presentations, diagnosis using imaging and other tests, and treatment approaches are outlined for each of the major lesion types. Surgical resection and other procedures are discussed as primary treatment methods depending on the specific lesion.
Thyroid malignancies are the most common endocrine malignancies. The annual incidence is 3.7 per 100,000 people with a 3:1 female to male ratio. The main types are papillary carcinoma (60% of cases), follicular carcinoma (17%), anaplastic carcinoma (13%), and medullary carcinoma (6%). Risk factors include a history of radiation exposure, family history, and certain genetic syndromes. Presentation varies from asymptomatic thyroid nodules to symptoms of compression. Treatment depends on the type and stage of cancer, and may include surgery, radioactive iodine therapy, chemotherapy, and external beam radiation. Prognosis ranges from generally good for differentiated cancers to very poor for anap
Meningioma is a type of tumor that arises from the meninges, the membranes surrounding the brain and spinal cord. It is the most common non-cancerous brain tumor, accounting for 20% of all primary brain tumors. The standard treatment is surgical resection if the tumor is symptomatic or growing in size. For inoperable or recurrent tumors, radiation therapy and medical therapies may be options, though medical therapies have limited effectiveness. The prognosis depends on the tumor grade, with lower grade tumors having better outcomes.
This document provides information about acoustic neuromas (vestibular schwannomas). It defines acoustic neuromas as benign tumors of vestibular nerve schwann cells that arise from the schwann cells within the internal auditory canal. The document discusses the pathogenesis, clinical presentation in different stages, diagnostic evaluations including audiological and radiological tests, differential diagnosis, and treatment options including surgery, observation, and radiotherapy.
This document provides a summary of imaging features of lesions in the anterior skull base region, including sinonasal neoplasms such as squamous cell carcinoma, adenocarcinoma, esthesioneuroblastoma, malignant melanoma, and lymphoma. Key imaging findings discussed include tumor appearance on CT and MRI, characteristics of bone and soft tissue involvement, and distinguishing features between lesion types. Imaging plays an important role in diagnosis and surgical planning for anterior skull base pathology.
General Basic knowledge of Brain tumour explained in brief of classification, pathogenesis, clinical features, CT, MRI, management, Radiotherapy. Best for MBBS and PG preparation student.
This document provides an overview of parapharyngeal space tumors including:
- Anatomy and divisions of the parapharyngeal space
- Common tumor types including salivary gland tumors, neurogenic tumors, and others
- Evaluation with imaging such as CT and MRI
- Surgical approaches including transoral, cervical, and infratemporal fossa approaches
- Specific details on paragangliomas, including carotid body and jugulotympanic tumors
This document discusses brain tumors, including their classification, pathophysiology, clinical manifestations, diagnosis, and treatment. Brain tumors are classified based on their location and cell type, with the most common being gliomas that infiltrate brain tissue. Symptoms vary depending on the tumor location but can include headaches, vomiting, visual issues, seizures, and neurological deficits. Diagnosis involves imaging tests like CT and MRI scans along with possible biopsy. Treatment involves surgical resection when possible along with chemotherapy, radiation therapy, and corticosteroids. Nursing focuses on managing symptoms and self-care deficits caused by neurological impairment or treatment side effects like nutritional issues.
Similar to Meningioma presentation by dr,Mumtaz Ali narejo (20)
This document outlines the key aspects of head injury including:
- Head injuries are the most common cause of prehospital deaths and range from mild to severe.
- The primary survey focuses on airway, breathing, circulation, disability, and exposure to stabilize the patient. The secondary survey involves a full neurological exam and diagnostic testing.
- Treatment depends on the severity and includes intravenous fluids, oxygen therapy, hyperventilation, mannitol, hypertonic saline, barbiturates, and surgery for mass lesions or fractures. Brain death is defined by specific clinical criteria including absent brainstem reflexes and no brain activity on tests.
This document outlines types of spine injuries, their effects, documentation requirements, and general management. It discusses that 25% of major trauma injuries involve the spine, with the cervical spine making up 55% of cases. Spine injuries can cause respiratory failure if they involve certain levels of the cervical or thoracic spine due to effects on intercostal muscles and the diaphragm. Documentation of spine injuries should include level, bony or neurological involvement, and whether it is complete or incomplete. General management includes spinal motion restriction, careful patient transfer techniques, administration of fluids and steroids, and DVT prophylaxis.
This document provides an overview of statistical software packages including their common features, advantages, types, and most common packages used in social science. It discusses features of Microsoft Excel, SPSS, SAS, Stata, R, Minitab, and GraphPad Prism. These software packages vary in their ease of use, available statistical analyses, programming capabilities, and cost. Excel is best for basic statistics while SAS and Stata provide more advanced analyses but are harder to use. SPSS and Minitab offer a good balance of capabilities and usability.
This document presents a case report of a 25-year-old man who presented with progressive hearing loss over 15 years, right-sided facial weakness for 6 months, and difficulty walking for 5 years. On examination, he had positive whisper and Rhinne's tests bilaterally, as well as right-sided cerebellar signs and facial weakness. An MRI of the brain and inner ear function tests were ordered. The document lists the patient's history and examination findings but does not provide the results of the ordered tests or a diagnosis. The differential diagnoses being considered are not specified.
Protein microarrays are a high-throughput method to study protein interactions and function on a large scale. The microarray consists of capture proteins bound to a solid surface, such as a glass slide. Probe molecules, typically labeled with a fluorescent dye, are added and any reactions emit signals detected by a laser scanner. A variety of methods can be used to prepare the microarray by immobilizing proteins to the solid surface while maintaining their structure and binding abilities. Protein microarrays have applications in diagnostics, proteomics, and antibody characterization. However, working with proteins presents challenges including maintaining their stability on the surface and reducing non-specific binding.
This document outlines traumatic brain injury, including its incidence, mechanisms, symptoms, neurological examination findings, and various types of injuries seen on imaging like contusions, hematomas, and skull fractures. It discusses the Monro-Kellie doctrine and treatments for traumatic brain injury, including both medical management with medications, fluids and monitoring, as well as various surgical procedures to evacuate hematomas.
This document outlines a plan to reduce traumatic brain injuries from road traffic accidents. It discusses that road traffic accidents are the leading cause of death for people aged 15-29 worldwide, killing nearly 1.3 million people and injuring 20-50 million more each year. The plan proposes focusing on improving road safety management, safer road infrastructure, safer vehicles, safer road user behavior, and enhancing post-crash response through strategies like implementing graduated driver licensing programs, setting and enforcing speed limits, increasing seatbelt and helmet use, reducing drunk driving, and strengthening emergency response systems. The goal is to cut deaths and injuries from traffic accidents through low-cost road improvements and promoting protective equipment.
This document outlines different types of spinal injuries and provides key details about each. It begins with an overview of spinal cord tracts and classifications of complete versus incomplete cord injuries. Various syndromes of incomplete cord injuries are described. Distinctions between conus medullaris and cauda equina injuries are noted. Spinal shock is defined as a transient loss of neurologic function below the level of injury. Specific injury types are outlined for different spinal regions from C1 to the coccyx, including things like odontoid fractures, hangman's fractures, and burst fractures. Graphs are referenced to depict spinal tracts.
This document provides an outline for a lecture on spine pathology for final year medical students. It covers spinal anatomy, trauma, degenerative diseases, tumors, infections, congenital abnormalities, deformities, and metabolic bone diseases. For each topic, key points are outlined such as epidemiology, clinical presentation, diagnostic imaging, and management principles. Spinal anatomy includes the vertebrae, spinal cord, and blood supply. Trauma management focuses on spinal alignment and stabilization. Degenerative diseases discussed are disc herniation and spinal stenosis. Infections can be pyogenic or tuberculosis. Congenital conditions include spina bifida and syringomyelia. Metabolic bone disease highlights osteoporosis. The document concludes with an
This document discusses neuromuscular transmission and excitation-contraction coupling at the neuromuscular junction (NMJ). It describes the secretion of acetylcholine (Ach) from nerve terminals, how Ach opens ion channels on the postsynaptic membrane, and how this leads to end plate potentials and excitation of skeletal muscle fibers. The document also discusses Ach formation and release, safety factors at the NMJ, fatigue of the NMJ, and the molecular mechanisms of excitation-contraction coupling in skeletal muscle.
This document summarizes the anatomy and physiology of skeletal muscle contraction. It describes the gross and molecular structures of muscle fibers, including the sarcomere unit composed of actin and myosin filaments. The sliding filament model of contraction is explained, where crossbridges on the myosin head bind to actin and hydrolyze ATP for movement. Calcium released from the sarcoplasmic reticulum initiates the crossbridge cycling. Fast and slow muscle fiber types are compared. The energetics and mechanisms of isotonic and isometric contractions are also summarized.
This document describes the medical history, examination, diagnosis, and treatment for a 38-year-old male patient presenting with decreased hearing in his left ear over 7 months and falling to his left side over 5 months. MRI and CT scans revealed a left cerebellopontine angle schwannoma with hydrocephalus. The patient underwent VP shunt placement followed by a left retrosigmoid approach for tumor resection. Post-operatively, the patient was monitored for complications which can include cranial nerve injuries, CSF leakage, meningitis, and recurrence of the tumor. The outcomes for this type of surgery generally have high rates of gross total resection, hearing preservation, and facial nerve function preservation depending on the size and classification of the
A 15-year-old female presented with neck pain radiating to the scapular blade for 4 months and progressive weakness starting in the left side 4 months ago and right side 3 months ago. On examination, she had weakness, increased tone and reflexes more on the left side. Imaging showed an extramedullary tumor at the upper cervical spine. She underwent a posterior midline laminectomy with microscopic dissection and excision of the tumor. Post-operatively, she was monitored for complications like nerve root injury, spinal cord injury, CSF leak, or tumor recurrence.
A 22-year-old male presented with a 1-year history of back pain and 8 months of lower limb weakness and difficulty walking. MRI revealed a tumor in the lower dorsal spine. The patient underwent a posterior midline approach and excision of the tumor. Possible diagnoses included ependymoma, astrocytoma, or tuberculosis of the spine. The surgery aimed to prevent further neurological dysfunction and cure the condition through complete tumor resection.
A 25-year-old female presented with a one-year history of lower back pain radiating to both legs. Examination revealed decreased pinprick sensation in the left leg. MRI showed a tumor at L5. The diagnosis was cauda equina syndrome secondary to a spinal meningioma at L5. The patient underwent posterior laminectomy and excision of the tumor. Post-operatively, the patient's pain improved.
A 28-year-old female presented with a 1-year history of headaches and 1-month history of double vision. Examination found double vision in the right upper and lower visual fields. Imaging revealed a right frontotemporal mass, and the patient underwent a right pterional craniotomy for total excision of a sphenoid wing meningioma. Post-operatively, the patient received follow-up care and rehabilitation with the goal of reducing risk of recurrence.
This document describes the medical history and examination of a 28-year-old female patient presenting with proptosis of the right eye and decreased vision in that eye for 3 years. On examination, protrusion of the right eyeball was noted. Vision was reduced to finger counting in the right eye compared to 6/6 in the left eye. Neurological examination was normal except for slight restriction of abduction of the right eyeball. The patient was admitted for further investigation and management of a suspected orbital tumor.
A 45-year-old female presented with a 1-year history of headaches and recent onset of vision loss, smell loss, and urinary incontinence. Examination found visual impairment, anosmia, and papilledema in one eye with optic atrophy in the other. Imaging revealed a likely anterior skull base tumor involving the frontal lobe, with differential diagnoses including meningioma, pituitary adenoma, or fungal infection. The patient underwent a bifrontal craniotomy for tumor excision. Postoperative complications can include issues like CSF leak, hemorrhage, or deficits in motor function or vision. Long-term outcomes depend on factors like the tumor grade, extent of resection, and use of radiation therapy
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
2. OUTLINES
• Main features
• Common location
• Investigations
• Types
• Sindou et All
• Surgical principles
• Simpson grading
• Histopathological grading
• Recurrence rate
• Radiotherapy
3. Main Features
• Most common primary intracranial tumors
• Extra-axial
• F:M = 1.8:1
• Mean age : 45 years
• usually slow growing
• circumscribed (non-infiltrating)
• benign lesions
• arachnoid cap cells (meningothelial cells)
• Ectopic meningiomas
• Psammoma bodies
17. SURGERY : PRINCIPLE
• Preoperative embolization
• Autologous blood donation
• Early interruption of the blood supply
• Internal decompression
• Dissection of the tumor capsule
• Removal of attached bone & dura