A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle.
More than half of all proteins interact with membranes.
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle.
More than half of all proteins interact with membranes.
This presentation contains the introduction to the structure of plasma membrane. This gives an insight into the biochemistry of the plasma membrane and the singer and nicholsan model.
Describes the plasma membrane in detail, explains the each major component with its functions.
Transport mechanism across the cell is covered with detailed explanation with examples.
by Dr. N.Sivaranjani, MD
Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins
Membrane proteins are proteins that interact with, or are part of, biological membranes. They include integral membrane proteins that are permanently anchored to the membrane and peripheral membrane proteins which are only temporarily attached to the lipid bilayer or to integral proteins.
This presentation contains the introduction to the structure of plasma membrane. This gives an insight into the biochemistry of the plasma membrane and the singer and nicholsan model.
Describes the plasma membrane in detail, explains the each major component with its functions.
Transport mechanism across the cell is covered with detailed explanation with examples.
by Dr. N.Sivaranjani, MD
Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins
Membrane proteins are proteins that interact with, or are part of, biological membranes. They include integral membrane proteins that are permanently anchored to the membrane and peripheral membrane proteins which are only temporarily attached to the lipid bilayer or to integral proteins.
The plasma membrane, which is also called the cell membrane, has many functions, but the most basic one is to define the borders of the cell and keep the cell functional.
. Introduction
2. Cell / Plasma membrane
3. Transport across membrane
Passive transport
a.Osmosis
b. Simple diffusion
c. Facilitated diffusion
Active transport
a. Primary active transport
b. Secondary active transport
Example-
1. Na+/K+ ATPase
2. Ca+ ATPase
3. Proton pump
4. Transport of large molecule by plasma membrane
Endocytosis
Exocytosis
5. Transport of nutrients by membraneprotiens
Channel protein
Carrier proteins
6. Role of membrane Transport
7. Conclusion
8. Reference
18. Osmolarity and Tonicity Comparison Compare to Fig 5-35 A is isosmotic to B A is hypotonic to B
19.
20. the end Electrical Disequilibrium and Resting Membrane Potential (pp.156-163) will be covered at the beginning of Ch 8
21.
22.
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25.
26.
Editor's Notes
Familial Hypercholesterolemia is an autosomal dominate disease which occurs about 1 in every 500 people . The homozygous FH is more rare, occuring with the frequency of about 1 in a million. The statistics for the homozygous FH is not surprising though, since patients suffering from two alleles of this gene usually do not survive pass their teens. The condition of hypercholesterolemia in FH patients are detectable at birth or shortly thereafter. The cholesterol levels in heterozygous patients are between350 to 500 mg/dL, and in homozygous, the levels are between 700 to 1,200 mg/dL (see NCEP table for comparison).
large lipophobic molecule secretion: mucus and protein hormones
Ouabain = Na + /K + -ATPase inhibitor – cannot penetrate through cell membrane.
Is osmosis the same as the diffusion of water? Almost but not exactly. -volume change Force (such as pressure) can oppose osmosis not diffusion
NaCl is considered to be functionally nonpenetrating, as it gets pumped out of cell as soon as it enters.
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