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CELL TRANSPORT
TASK 3
BODY WATER
• Water provides a fluid environment for communication and
molecular transport throughout the body.
• Person’s hydration: water conducts electricity;
↓ hydration lvl. = ↑ resistance to electrical flow through the body
• Total body water (of 70 kg) is approx. 40 L (obese – as low as 45%).
• Distributed among fluid compartments
3.1. CHEMICAL COMPOSITION OF
INTRACELLULAR AND EXTRACELLULAR FLUID
• Extra (Table)
• Intra
INTRACELLULAR FLUID EXTRACELLULAR FLUID
• liquid found inside cells –
cytosol
• cytosol - complex mixture of
substances: proteins, ions, and
organelles dissolved in water
• or EXTRACELLULAR FLUID
VOLUME (ECFV)
• body fluid outside of cells
• consists: plasma, interstitial,
and transcellular fluid
INTRACELLULAR FLUID EXTRACELLULAR FLUID
CHEMICAL COMPOSITIONS
• Cytosol – 70% water
• pH 7.4
• ↑ amount of charged
macromolecules such as proteins
and nucleic acids than outside
• Plasma – 95% water
• ↑concentration Potassium ion
• ↓ concentration Sodium ion
• Cations: Sodium, Potassium,
Calcium
• Anions: Chlorine, Hydrogen
Carbonate
• Contains: proteins, glucose,
clotting factors, minerals,
hormones, CO2
3.2 DIFFERENTIATE BETWEEN
DIFFUSION AND ACTIVE
TRANSPORT
DIFFUSION ACTIVE TRANSPORT
DEFINITION
passive movement of molecules along a
concentration gradient of higher
concentration to a lower concentration.
movement of particles across a cellular
membrane from a lower to a higher
concentration by the use of metabolic
energy.
METABOLIC ENERGY (main difference)
which does not require metabolic energy
in order to transport molecules across
the cell membrane.
requires metabolic energy in the form of
ATP for the transportation of molecules
across the cell membrane.
FUNCTIONS
maintains a dynamic equilibrium of
water, gases, nutrients, and wastes in
and out of the cell.
allows the transportation of molecules
like nutrients and wastes against the
concentration gradient.
DIFFUSION ACTIVE TRANSPORT
EQUILIBRIUM
No net movement of molecules is
observed after the establishment of
equilibrium on either side of the
membrane.
No equilibrium of molecules is
established in active transport.
TYPES OF PARTICLES
Water, oxygen, carbon dioxide, small
monosaccharides, sex hormones and
other small, hydrophobic molecules
Proteins, ions, complex sugars, and large
cells
EXAMPLE
Oxygen moving from the airways and
diffusion of molecules from the blood to
the cells through the interstitial fluid
Taking up nutrients, endocytosis,
exocytosis, sodium/potassium pump,
and secretion of a substance into the
blood stream

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Medicine Level 1 Physiology: Cell Transport

  • 2. BODY WATER • Water provides a fluid environment for communication and molecular transport throughout the body. • Person’s hydration: water conducts electricity; ↓ hydration lvl. = ↑ resistance to electrical flow through the body • Total body water (of 70 kg) is approx. 40 L (obese – as low as 45%). • Distributed among fluid compartments
  • 3. 3.1. CHEMICAL COMPOSITION OF INTRACELLULAR AND EXTRACELLULAR FLUID • Extra (Table) • Intra
  • 4. INTRACELLULAR FLUID EXTRACELLULAR FLUID • liquid found inside cells – cytosol • cytosol - complex mixture of substances: proteins, ions, and organelles dissolved in water • or EXTRACELLULAR FLUID VOLUME (ECFV) • body fluid outside of cells • consists: plasma, interstitial, and transcellular fluid
  • 5. INTRACELLULAR FLUID EXTRACELLULAR FLUID CHEMICAL COMPOSITIONS • Cytosol – 70% water • pH 7.4 • ↑ amount of charged macromolecules such as proteins and nucleic acids than outside • Plasma – 95% water • ↑concentration Potassium ion • ↓ concentration Sodium ion • Cations: Sodium, Potassium, Calcium • Anions: Chlorine, Hydrogen Carbonate • Contains: proteins, glucose, clotting factors, minerals, hormones, CO2
  • 6. 3.2 DIFFERENTIATE BETWEEN DIFFUSION AND ACTIVE TRANSPORT
  • 7. DIFFUSION ACTIVE TRANSPORT DEFINITION passive movement of molecules along a concentration gradient of higher concentration to a lower concentration. movement of particles across a cellular membrane from a lower to a higher concentration by the use of metabolic energy. METABOLIC ENERGY (main difference) which does not require metabolic energy in order to transport molecules across the cell membrane. requires metabolic energy in the form of ATP for the transportation of molecules across the cell membrane. FUNCTIONS maintains a dynamic equilibrium of water, gases, nutrients, and wastes in and out of the cell. allows the transportation of molecules like nutrients and wastes against the concentration gradient.
  • 8. DIFFUSION ACTIVE TRANSPORT EQUILIBRIUM No net movement of molecules is observed after the establishment of equilibrium on either side of the membrane. No equilibrium of molecules is established in active transport. TYPES OF PARTICLES Water, oxygen, carbon dioxide, small monosaccharides, sex hormones and other small, hydrophobic molecules Proteins, ions, complex sugars, and large cells EXAMPLE Oxygen moving from the airways and diffusion of molecules from the blood to the cells through the interstitial fluid Taking up nutrients, endocytosis, exocytosis, sodium/potassium pump, and secretion of a substance into the blood stream