This document discusses ptosis (drooping of the upper eyelid) including its definition, evaluation, classification, and treatment options. Ptosis is evaluated based on 5 clinical measurements including margin-reflex distance, vertical palpebral fissure height, upper eyelid crease position, levator function, and presence of lagophthalmos. The most common form is aponeurotic ptosis which is caused by stretching or dehiscence of the levator aponeurosis. Treatment depends on the degree of ptosis and levator function, and may include levator resection, Muller's muscle shortening, or brow suspension. Levator resection is suitable for mild ptosis with good levator function,
slide presentation about ptosis in ophthalmology department
including mechanical,myogenic,aponeurotic,traumatic,neurogenic cause
plus dermatochalasis
in general appraoch and surgery choice
Ptosis evaluation is very important in making decision which type of management is suitable to your patients.
This presentation summaries an important test which are required to do when you face a patient with ptosis
slide presentation about ptosis in ophthalmology department
including mechanical,myogenic,aponeurotic,traumatic,neurogenic cause
plus dermatochalasis
in general appraoch and surgery choice
Ptosis evaluation is very important in making decision which type of management is suitable to your patients.
This presentation summaries an important test which are required to do when you face a patient with ptosis
An important instrument in every day job of critical ill patients . This work shop has been performed to help clinicians to understand how to deal with direct ophthalmoscope and organize diagnostic and life saving fundoscopy findings .
you will get knowledge about the ptosis, its different types, its examination, its measurement, its treatment in detail.
different eyelid muscles such as LPS, Orbicularis oculi and frontalis are also explained.
Principles and technique of pneumatic retinopexy (Dr. Avuru C.J).pptxAVURUCHUKWUNALUJAMES1
Retinal detachment surgeries, principles and technique of pneumatic retinopexy, current trend in retinal detachment surgeries, development of skills in binocular indirect ophthalmoscopic examination, residency traning presentation, University college hospital Ibadan, Oyo state Nigeria, Vitreo-retinal subspecialty training, West african college of surgeons, federal teaching hospital, Lokoja, Kogi state, Nigeria.
An important instrument in every day job of critical ill patients . This work shop has been performed to help clinicians to understand how to deal with direct ophthalmoscope and organize diagnostic and life saving fundoscopy findings .
you will get knowledge about the ptosis, its different types, its examination, its measurement, its treatment in detail.
different eyelid muscles such as LPS, Orbicularis oculi and frontalis are also explained.
Principles and technique of pneumatic retinopexy (Dr. Avuru C.J).pptxAVURUCHUKWUNALUJAMES1
Retinal detachment surgeries, principles and technique of pneumatic retinopexy, current trend in retinal detachment surgeries, development of skills in binocular indirect ophthalmoscopic examination, residency traning presentation, University college hospital Ibadan, Oyo state Nigeria, Vitreo-retinal subspecialty training, West african college of surgeons, federal teaching hospital, Lokoja, Kogi state, Nigeria.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
3. Definition
Ptosis ( in greek means to fall) is the
abnormal drooping of the upper
eyelid. Normally upper lid covers
about upper one sixth of the cornea
i.e about 2mm. Therefore in ptosis it
covers more than 2 mm.
10. 5 clinical measurement
• Margin-reflex distance
• Vertical palpebral fissure height
• Upper eyelid crease position
• Levator Funtion (upper lid excursion)
• Presence of lagophthalmos
11.
12. Margin-reflex
distance
• MRD1 : distance from the upper eyelid
margin to the corneal light reflex in
primary position
• MRD2 : distance from the lower eyelid
margin to the corneal light reflex in
primary position
• MRD1=Single most important
measurement
• MRD1+MRD2=Palpebral fissure
14. Upper
Eyelid
Crease
Position
• Distance from the upper eyelid crease to
eyelid margin is measured
• Insertion of fibers from the levator
muscle into the skinupper eyelid crease
• 8-9 mm in males and 9-11 mm in females
• Upper eyelid crease is typically lower or
obscured in the Asian eyelid, with or
without ptosis
15.
16. Levator Function
• Upper eyelid excursion
from downgaze to
upgaze with frontalis
muscle function
negated
17. Lagophthalmos • Note the gap between the eyelids in mm
• Record the tear film quantity and quality
18. Ancillary Test
• Visual field testing with the eyelids untaped vs
taped improvement indicates better vision
with eyelid surgery
• Pharmacologic testing, pupillary evaluation in
light and dark, reverse ptosis of the lower
eyelid
21. Aponeurotic ptosis
• Acquired aponeurotic ptosis is the most common
form of ptosis
• Stretching or dehiscence of the levator
aponeurosis or disinsertion from its normal
position
• Common causes are involutional attenuation or
repetitive traction on the eyelid
• Frequent eye rubbing or prolonged use of rigid
contact lenses
• Exacerbated by intraocular surgery or eyelid
surgery
22.
23. characteristic • High or absent upper eyelid crease
secondary to upward displacement or
loss of the insertion of the levator
fibers into the skin
• Thinning of the eyelid superior to the
upper tarsal plate is often an
association finding
• Levator function is normal (12-15mm)
• Worsen in downgaze
• Limit the superior visual field
24.
25. MECHANICAL PTOSIS
• Refers to the condition in which an eyelid or
orbital mass weighs or pulls down the upper
eyelid, resulting in inferior displacement
• Plexiform neurofibroma
• Hemangioma
• Acquired neoplasm
• Large chalazion
• Postsurgical, posttraumatic edema
• Etc…….
28. Key factor
• The amount of ptosis and the function of the levator
muscle are the key factors
• Levator resection is suitable for any amount of ptosis
with a levator function better than 4 mm
• Muller’s muscle shortening:The Fasanella-Servat
operation was the first operation of this type. These
operations are appropriate only if the levator function is
at least 10 mm and there is a maximum of 2 mm of
ptosis. The instillation of phenylephrine 10% (or 2.5%)
will restore the affected lid to its normal position in
suitable patients.
• Brow suspension is the only procedure which will give a
lasting correction if the levator function is 4 mm or less.
29. Consideration Procedure of choice
LF>4mm Levator resection
LF>10mm, ptosis<2mm, response to
phrenylnephrine stimulation
Muller’s muscle shortening
LF<4mm Brow suspension
30. Levator Aponeurosis repair
• Choice of approach to the levator The anterior (skin) approach
is familiar, it allows skin to be excised and it leaves the
conjunctiva intact. The posterior (conjunctival) approach,
although less familiar at first, allows more postoperative
control of the lid height.
• Anterior vs Posterior levator aponeurosis repair
36. Levator resection
• Remember that levator resection can lead to change in height of eyelid
within first 6 weeks
• Rule of thumb lid may rise 1-2 mm if LF > 7 mm and may drop 1-2 mm if
LF<7mm
• Beard’s recommended figures for congenital ptosis give some guidance to
predict final result of surgery
37.
38.
39.
40.
41.
42.
43. Muller’s muscle shortening
• If phenylnephrine test is strongly positive ( restoring the
affected lid to its normal position) Mullerectomy is highly
recommended
• 1.Measure MRD1
• 2.Instill phenylnephrine 10% into superior fornix of the eye
with ptosis (If cardiac condition is presented
phenylnephrine 2.5% may be used instead)
• 3.Wait for 5 minutes
• 4.measure MRD1
• If MRD1 improves after phenylnephrines test then this is
positive result
• And an improved MRD1 can indicate the length of muller’s
muscle and conjunctiva to be resected
44. Type of response suggestion
Normal level Resect 8 mm
Higher than desired level Resect 6.5-8 mm
Lower than desired level Resect 8-9.5 mm
Little response or none Do something else
45.
46. Muller’s muscle and conjunctiva shortening
without tarsal plate excision (Open Technique)
47.
48. Frontalis/Brow suspension
• Children<4yrs FOX procedure (for later surgery if
ptosis recur)
• Older children and adults Crawford method
• If unilateral ptosis bilateral brow suspension is still
recommended to maintain indifferent movement
• If one eye is good and one eye is not good weaken
the one with good LF is suggested
• Material= autogenous fascia lata is the best material
when available
• If not available silicone is prefered,Alloderm and
Frozen dura matter may be used
55. Medical therapy
Patients with myasthenia gravis may improve with medical
treatment. Sympathomimetic topical eye drops such as
apraclonidine and phenylephrine provide short temporary
lift of the upper eyelid in some patients. Use of topical
oxymetazoline hydrochloride (0.1%) for blepharoptosis
received FDA approval in July 2020