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Ptosis & It’s Management
Dr.Md.Ashfakur Rahaman(Rayhan)
DO Student
Dept.of Ophthalmology
Rangpur Medical College
OBJECTIVES
DEFINITION
TYPES
EXAMINATION
TREATMENT
Normal lid Position
• Upper lid covers 2 mm of cornea
.
• Lower lid touches the limbus
DEFINITION
Abnormally low position of upper eyelids is called ptosis which may be
Congenital or Acquired.
Classification Of Ptosis
CONGENITAL PTOSIS
• Simple congenital ptosis
Congenital ptosis associated with
• Blepharophimosis syndrome
• Marcus gunn jaw winking
phenomenon
• 5.
ACQUIRED PTOSIS
• Neurogenic ptosis
-Third nerve palsy
-Third nerve misdirection
-Horner syndrome
• Myogenic ptosis
-Myasthenia gravis
-Myotonic dystrophy
-Progressive external Ophthalmoplegia
• Aponeurotic ptosis
• Mechanical ptosis
Simple Congenital Ptosis
• Developmental dystrophy of levator muscle
• Occasionally associated with weakness of superior rectus
• Unilateral or bilateral ptosis of varying severity
• In downgaze ptotic eyelid is slightly higher
• Frequent absence of upper lid crease
• Usually poor levator function
Blepharophimosis syndrome
• Moderate to severe symmetrical ptosis
• Short horizontal palpebral aperture
• Telecanthus (lateral displacement of medial canthus)
• Epicanthus inversus (lower lid fold larger than upper)
• Lateral inferior ectropion
• Poorly developed nasal bridge and hypoplasia of superior orbital rims
Marcus Gunn jaw-winking Phenomenon
• Accounts for about 5% of all cases of congenital ptosis
• Retraction or ‘wink’ of ptotic lid in conjunction with stimulation of
ipsilateral pterygoid muscles
Grading of Marcus Gunn jaw-winking Phenomenon
• Mild- maximum elevation of ptotic eyelid non- ptotic position
• Moderate- maximum elevation goes upto superior limbus
• Severe- maximum elevation beyond the superior limbus with scleral
show
Retraction of lid on Opening of mouth
NEUROGENIC PTOSIS
THIRD NERVE PALSY
Congenital or acquired .
- Eyeball is turned down, out slightly intorted due to actions of lateral
rectus and superior oblique muscles.
- Ocular movements restricted in all directions except outward.
- Pupil is fixed and dilated due to paralysis of spinchter pupillae
muscle.
- Accommodation is completely lost due to paralysis of ciliary muscle
THIRD NERVE MISDIRECTION
Rare, unilateral
- Pupil is occasionally
involved
-Bizarre movements of upper
lid accompany eye movements
HORNER SYNDROME:
Characterized by classic triad of:
• Mild ptosis
• Miosis
• Reduced ipsilateral sweating
Other features include
• mild enophthalmos
• loss of cilio- spinal reflex
• heterochromia
• pupil is slow to dilate
• slight elevation of the lower
eyelid
Bell’s phenomenon
• Upward rotation of globe on lid closure
GRADING
good= >2/3 of cornea disappears
fair= 1/3 – 2/3 of cornea disappears
poor= <1/3 of cornea disappears
VARIANT
- Inverse- upward & inward
- Reverse- downward & outward
- Preverse- different directions
Cont...
• Corneal sensation- always check before planning the surgery.
• Schirmers test – to rule out dry eye disease
• Pupillary abnormalities
- miosis in horner’s syndrome
-mydriasis in 3rd nerve palsy
Phenylephrine test
The function of muller’s is tested by applying drops of 10%
phenylephrine to the eye on the side of blepharoptosis.
Myasthenia Gravis
Clinical features
• Uncommon, typically affects young women
• Weakness and fatiguability of voluntary musculature
• Three types - ocular, bulbar and generalized
Cogan‘s Lid Twitch Sign
Characteristic of myasthenia
• consists of a brief overshoot twitch of lid retraction following sudden
return of the eyes to primary position after a period of downgaze
Investigations
• Ice pack test
• Edrophonium test
• Antibodies to acetylcholine
receptors
• CT or MRI for presence of
thymoma
• Electromyography to confirm
fatigue
Other Test for Myasthenia
• Generalized fatigue
• Lid fatigue
• Sleep test
ICE TEST
• An ice pack is applied to the affected upper eyelid for 5 minutes.
• A positive test is the improvement of ptosis by > 2mm or more.
Edrophonium (Tensilon)test
• Measure amount of ptosis or diplopia
before injection
• Inject i.v. atropine 0.3 mg
• Inject i.v. test dose
of edrophonium (0.2 ml-2 mg)
• Inject remaining (0.8 ml-8 mg)
if no hypersensitivity
Treatment options
Medical –
anticholinesterases
steroids and azathioprine
Thymectomy
Ocular myasthenia
• Insidious, bilateral but asymmetrical
• Worse with fatigue and in upgaze Ptosis
• Ptotic lid may show ‘twitch’ and ‘hop’ signs
• Intermittent and usually vertical Diplopia
Myotonic dystrophy
• Facial weakness and ptosis
• Involvement of tongue and
pharyngeal muscles
• Ophthalmoplegia - uncommon
• Muscle wasting
• Hypogonadism
• Intellectual deterioration
• Presenile cataracts
• Release of grip difficult
Aponeurotic ptosis
• Age related
• Caused by dehiscence,disinsertion or stretching of levetor aponeurosis
• Worsens towards the end of the day
Mechanical ptosis
Large tumours
• Caused by gravitational effect of mass
Or by scarring.
Anterior orbital lesions
Severe lid oedema
Causes of pseudoptosis
• Lack of lid support
• Contralateral lid retraction
• Ipsilateral hypotropia
• Brow ptosis
• Dermatochalasis
Clinical Evaluation Of Ptosis
When patient enters examination room, observation of the head posture
with chin elevation and frontalis overaction indicate severe ptosis.
Hand shake for exclude Myotonia
Clinical Cont..
HISTORY
• Age of onset
• Duration
• Unilateral/bilateral
• Weather ptosis worsen through
the day
• Diplopia
• Muscle weakness
• trauma/ surgery
• lid edema
• previous ptosis surgery
Cont..
• Presence of any aberrant lid movements
• Weather eye movements are impaired
• Past medical history
• Current medications
• Family history
• Old photographs
EXAMINATION
• Head posture
• Vision
• Periocular fullness
• Frontalis overaction
• Scar mark
• Lid skin laxity
• Telecanthus, epicanthus inversus
Ocular Motility:
• Importance in myogenic ptosis,
• To R 3rd nerve palsy
• presence of strabismus, especially vertical strabismus entails that it be
corrected prior to the correction of the ptosis.
Visual acuity
• Best-corrected visual acuity should be assessed to record any
amblyopia if present, especially in cases of congenital ptosis
MEASUREMENTS
Margin reflex distance
• Margin reflex distance 1(MRD 1)- After shining the torchlight in the
patient eye, the distance between the corneal light reflex to the centre
of the upper lid margin is measured.
• Normal value is 4- 4.5mm.
Margin reflex distance 2 (MRD 2)- the distance of corneal light reflex to
the centre of the lower eyelid margin in primary gaze.
Normal value is 5- 5.5mm
PALPABLE FISSURE HEIGHT
• Distance between yhe upper
lid margin and lower lid
margin.
Male 7-10mm
Female 8-12mm
Levator function test
• Levator function test- Excursion of upper eyelid from extreme
downgaze to extreme upgaze is a measure of LPS function, negating
the action of frontalis muscle (Berke’s method).
Cont...
• Levator function is graded as follows:
• Normal: 15mm or more
• Good : 12-14mm
• Fair : 5-11mm
• Poor : 4mm or less
Upper lid crease
• Vertical distance between lid margin and lid crease in downgaze
• Male 8mm & Female 10mm
• Absence of crease in Congenital ptosis
• High crease in Aponeurotic ptosis
Pretarsal show
Distance between lid margin and the skin fold in Primary position.
Associated signs
• The Pupil
• Increased Innervation
• Fatigability
• Ocular motility defects
• Jaw winking
• Bell phenomenon
• The tear film
Flow chart of Examination
Treatment
A. Non surgical- Rehabilitative crutch glasses
B. Surgical :Definitive treatment
1. Conjunctiva-Mullar resection ( Fasanella- Servat operation)
2. Levator advancement (resection)
3. Brow(frontalis) suspension
Conjunctiva-Mullar resection
• Best results upto 2mm congenital ptosis with minimum 10mm levator
action
• 2mm tarsectomy performed for every 1mm ptosis
• Used for mild neurogenic or myogenic ptosis
Fasanella- Servat operation
LEVATOR RESECTION
• Skin Approach(Everbusch operation)
• Conjunctival Approach
• Indication:-
Ptosis of any cause provided residual levetor function is at least 5mm.
Levator Resection
Brow (Frontalis) suspension
• Bilateral moderate to severe ptosis with poor levator action.
• Indication:-
Ptosis associated with third nerve palsy
Blepharosphimosis Syndrome etc.
Brow (Frontalis) suspension
Complication
• Undercorrection
• Overcorrections
• Eyelid crease abnormalities:-
-Absence,Improper position
• Logopthalmos
• Exposure keratitis
• Recurrence following surgery
Photographic documentation- it is the most important aspect of ptosis
evaluation. Review of old photographs gives clue to the duration and
nature of ptosis.
So we should examine case of ptosis carefully before proceeding for
surgical management, to avoid any post operative surprise
Thank You

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Ptosis.dr Ashfak.pptx

  • 1. Ptosis & It’s Management Dr.Md.Ashfakur Rahaman(Rayhan) DO Student Dept.of Ophthalmology Rangpur Medical College
  • 3. Normal lid Position • Upper lid covers 2 mm of cornea . • Lower lid touches the limbus
  • 4. DEFINITION Abnormally low position of upper eyelids is called ptosis which may be Congenital or Acquired.
  • 5. Classification Of Ptosis CONGENITAL PTOSIS • Simple congenital ptosis Congenital ptosis associated with • Blepharophimosis syndrome • Marcus gunn jaw winking phenomenon • 5. ACQUIRED PTOSIS • Neurogenic ptosis -Third nerve palsy -Third nerve misdirection -Horner syndrome • Myogenic ptosis -Myasthenia gravis -Myotonic dystrophy -Progressive external Ophthalmoplegia • Aponeurotic ptosis • Mechanical ptosis
  • 6. Simple Congenital Ptosis • Developmental dystrophy of levator muscle • Occasionally associated with weakness of superior rectus • Unilateral or bilateral ptosis of varying severity • In downgaze ptotic eyelid is slightly higher • Frequent absence of upper lid crease • Usually poor levator function
  • 7.
  • 8. Blepharophimosis syndrome • Moderate to severe symmetrical ptosis • Short horizontal palpebral aperture • Telecanthus (lateral displacement of medial canthus) • Epicanthus inversus (lower lid fold larger than upper) • Lateral inferior ectropion • Poorly developed nasal bridge and hypoplasia of superior orbital rims
  • 9.
  • 10.
  • 11. Marcus Gunn jaw-winking Phenomenon • Accounts for about 5% of all cases of congenital ptosis • Retraction or ‘wink’ of ptotic lid in conjunction with stimulation of ipsilateral pterygoid muscles
  • 12. Grading of Marcus Gunn jaw-winking Phenomenon • Mild- maximum elevation of ptotic eyelid non- ptotic position • Moderate- maximum elevation goes upto superior limbus • Severe- maximum elevation beyond the superior limbus with scleral show
  • 13. Retraction of lid on Opening of mouth
  • 14. NEUROGENIC PTOSIS THIRD NERVE PALSY Congenital or acquired . - Eyeball is turned down, out slightly intorted due to actions of lateral rectus and superior oblique muscles. - Ocular movements restricted in all directions except outward. - Pupil is fixed and dilated due to paralysis of spinchter pupillae muscle. - Accommodation is completely lost due to paralysis of ciliary muscle
  • 15.
  • 16. THIRD NERVE MISDIRECTION Rare, unilateral - Pupil is occasionally involved -Bizarre movements of upper lid accompany eye movements
  • 17. HORNER SYNDROME: Characterized by classic triad of: • Mild ptosis • Miosis • Reduced ipsilateral sweating Other features include • mild enophthalmos • loss of cilio- spinal reflex • heterochromia • pupil is slow to dilate • slight elevation of the lower eyelid
  • 18.
  • 19. Bell’s phenomenon • Upward rotation of globe on lid closure GRADING good= >2/3 of cornea disappears fair= 1/3 – 2/3 of cornea disappears poor= <1/3 of cornea disappears VARIANT - Inverse- upward & inward - Reverse- downward & outward - Preverse- different directions
  • 20. Cont... • Corneal sensation- always check before planning the surgery. • Schirmers test – to rule out dry eye disease • Pupillary abnormalities - miosis in horner’s syndrome -mydriasis in 3rd nerve palsy
  • 21. Phenylephrine test The function of muller’s is tested by applying drops of 10% phenylephrine to the eye on the side of blepharoptosis.
  • 22. Myasthenia Gravis Clinical features • Uncommon, typically affects young women • Weakness and fatiguability of voluntary musculature • Three types - ocular, bulbar and generalized
  • 23. Cogan‘s Lid Twitch Sign Characteristic of myasthenia • consists of a brief overshoot twitch of lid retraction following sudden return of the eyes to primary position after a period of downgaze
  • 24. Investigations • Ice pack test • Edrophonium test • Antibodies to acetylcholine receptors • CT or MRI for presence of thymoma • Electromyography to confirm fatigue Other Test for Myasthenia • Generalized fatigue • Lid fatigue • Sleep test
  • 25. ICE TEST • An ice pack is applied to the affected upper eyelid for 5 minutes. • A positive test is the improvement of ptosis by > 2mm or more.
  • 26. Edrophonium (Tensilon)test • Measure amount of ptosis or diplopia before injection • Inject i.v. atropine 0.3 mg • Inject i.v. test dose of edrophonium (0.2 ml-2 mg) • Inject remaining (0.8 ml-8 mg) if no hypersensitivity
  • 28. Ocular myasthenia • Insidious, bilateral but asymmetrical • Worse with fatigue and in upgaze Ptosis • Ptotic lid may show ‘twitch’ and ‘hop’ signs • Intermittent and usually vertical Diplopia
  • 29.
  • 30. Myotonic dystrophy • Facial weakness and ptosis • Involvement of tongue and pharyngeal muscles • Ophthalmoplegia - uncommon • Muscle wasting • Hypogonadism • Intellectual deterioration • Presenile cataracts • Release of grip difficult
  • 31. Aponeurotic ptosis • Age related • Caused by dehiscence,disinsertion or stretching of levetor aponeurosis • Worsens towards the end of the day
  • 32.
  • 33. Mechanical ptosis Large tumours • Caused by gravitational effect of mass Or by scarring.
  • 35. Causes of pseudoptosis • Lack of lid support • Contralateral lid retraction • Ipsilateral hypotropia • Brow ptosis • Dermatochalasis
  • 36. Clinical Evaluation Of Ptosis When patient enters examination room, observation of the head posture with chin elevation and frontalis overaction indicate severe ptosis. Hand shake for exclude Myotonia
  • 37. Clinical Cont.. HISTORY • Age of onset • Duration • Unilateral/bilateral • Weather ptosis worsen through the day • Diplopia • Muscle weakness • trauma/ surgery • lid edema • previous ptosis surgery
  • 38. Cont.. • Presence of any aberrant lid movements • Weather eye movements are impaired • Past medical history • Current medications • Family history • Old photographs
  • 39. EXAMINATION • Head posture • Vision • Periocular fullness • Frontalis overaction • Scar mark • Lid skin laxity • Telecanthus, epicanthus inversus
  • 40. Ocular Motility: • Importance in myogenic ptosis, • To R 3rd nerve palsy • presence of strabismus, especially vertical strabismus entails that it be corrected prior to the correction of the ptosis. Visual acuity • Best-corrected visual acuity should be assessed to record any amblyopia if present, especially in cases of congenital ptosis
  • 41. MEASUREMENTS Margin reflex distance • Margin reflex distance 1(MRD 1)- After shining the torchlight in the patient eye, the distance between the corneal light reflex to the centre of the upper lid margin is measured. • Normal value is 4- 4.5mm.
  • 42. Margin reflex distance 2 (MRD 2)- the distance of corneal light reflex to the centre of the lower eyelid margin in primary gaze. Normal value is 5- 5.5mm
  • 43.
  • 44. PALPABLE FISSURE HEIGHT • Distance between yhe upper lid margin and lower lid margin. Male 7-10mm Female 8-12mm
  • 45. Levator function test • Levator function test- Excursion of upper eyelid from extreme downgaze to extreme upgaze is a measure of LPS function, negating the action of frontalis muscle (Berke’s method).
  • 46. Cont... • Levator function is graded as follows: • Normal: 15mm or more • Good : 12-14mm • Fair : 5-11mm • Poor : 4mm or less
  • 47. Upper lid crease • Vertical distance between lid margin and lid crease in downgaze • Male 8mm & Female 10mm • Absence of crease in Congenital ptosis • High crease in Aponeurotic ptosis Pretarsal show Distance between lid margin and the skin fold in Primary position.
  • 48. Associated signs • The Pupil • Increased Innervation • Fatigability • Ocular motility defects • Jaw winking • Bell phenomenon • The tear film
  • 49. Flow chart of Examination
  • 50. Treatment A. Non surgical- Rehabilitative crutch glasses B. Surgical :Definitive treatment 1. Conjunctiva-Mullar resection ( Fasanella- Servat operation) 2. Levator advancement (resection) 3. Brow(frontalis) suspension
  • 51. Conjunctiva-Mullar resection • Best results upto 2mm congenital ptosis with minimum 10mm levator action • 2mm tarsectomy performed for every 1mm ptosis • Used for mild neurogenic or myogenic ptosis
  • 53. LEVATOR RESECTION • Skin Approach(Everbusch operation) • Conjunctival Approach • Indication:- Ptosis of any cause provided residual levetor function is at least 5mm.
  • 55. Brow (Frontalis) suspension • Bilateral moderate to severe ptosis with poor levator action. • Indication:- Ptosis associated with third nerve palsy Blepharosphimosis Syndrome etc.
  • 57. Complication • Undercorrection • Overcorrections • Eyelid crease abnormalities:- -Absence,Improper position • Logopthalmos • Exposure keratitis • Recurrence following surgery
  • 58. Photographic documentation- it is the most important aspect of ptosis evaluation. Review of old photographs gives clue to the duration and nature of ptosis.
  • 59. So we should examine case of ptosis carefully before proceeding for surgical management, to avoid any post operative surprise