This study examined the effect of incorporating environmental distractors into a continuous performance test (CPT) on its ability to distinguish adolescents with ADHD from controls. The study found that ADHD adolescents made significantly more omission errors on a CPT when it included visual distractors or a combination of visual and auditory distractors compared to when there were no distractors. Distracting stimuli did not affect CPT performance in non-ADHD adolescents. The results suggest that including environmental distractors improves a CPT's ability to diagnose ADHD in adolescents by making the task more challenging for those with attentional difficulties.
The use of cardiac orienting responses as an early and scalable biomarker of ...BARRY STANLEY 2 fasd
Abstract
Background
Considered the leading cause of developmental disabilities worldwide, fetal alcohol spectrum disorders
(FASD) are a global health problem. To take advantage of neural plasticity, early identification of affected
infants is critical. The cardiac orienting response (COR) has been shown to be sensitive to the effects of
prenatal alcohol exposure and is an inexpensive, easy to administer assessment tool. The purpose of this
study was to evaluate the COR effectiveness in assessing individual risk of developmental delay.
The use of cardiac orienting responses as an early and scalable biomarker of ...BARRY STANLEY 2 fasd
Abstract
Background
Considered the leading cause of developmental disabilities worldwide, fetal alcohol spectrum disorders
(FASD) are a global health problem. To take advantage of neural plasticity, early identification of affected
infants is critical. The cardiac orienting response (COR) has been shown to be sensitive to the effects of
prenatal alcohol exposure and is an inexpensive, easy to administer assessment tool. The purpose of this
study was to evaluate the COR effectiveness in assessing individual risk of developmental delay.
School Entry Age: The younger group has more behavior and academic problemsYanki Yazgan
Sule Yazgan, M.D. and I represented our group of child psychiatry, pediatrics and psychology at the AAP 2015 meeting in Wash DC.
Sule presented data from a community based study that was conducted during the 2012-2013 academic year when the compulsory school age entry in Turkey was redefined as 60/66 months.
The study was led by Sebla Gokce, M.D. and I was the senior investigator.
Our findings showed that the 1st grade children who were under 72 months had more behavioral symptoms and functional impairment. There were more diagnosable cases of ADHD in the under 72 months group than the "older" children who became 1st graders after 72 months. The changes in school entry age appears to be associated with more children with ADHD symptoms and impairment in that urban sample.
We need to further elaborate the discussion and do quite a few analyses before we proceed with the write up. The findings are parallel to earlier findings of younger age in the classroom to be associated with more diagnoses of ADHD. Here we have an even younger than usual group whose symptom/impairment level and caseness escalated. Whether these changes in behavior led to an increase in the referrals and treatment for ADHD, and whether this findings is generalizable to more disadvantaged, semiurban and rural areas of Turkey await further research.
Your feedback will be welcome.
International Journal of Humanities and Social Science Invention (IJHSSI) is an international journal intended for professionals and researchers in all fields of Humanities and Social Science. IJHSSI publishes research articles and reviews within the whole field Humanities and Social Science, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Depression in Mothers of Children with Cerebral Palsy and Its Relation with C...ijtsrd
Introduction Cerebral palsy is a condition caused by an abnormality in the brain causing difficulties in movement and coordination, with an onset in the developmental period of childhood. Cerebral palsy can include cerebral malformation arising in the gestational period, a destructive process in the antenatal, prenatal or early postnatal periods, or by various processes acting together. Objective To evaluate the depression level in mothers of children with cerebral palsy and its relation with the current functional status of the children and establish To determine the correlation of functional ability of children with cerebral palsy and depression levels in their mother.Hypothesis There is inversely proportional relationship of depression of mother of children with cerebral palsy with current functional status of their children. There is directly proportional relationship of depression of mother of children with cerebral palsy with current functional status of their children.Design Pre test and post test experimental correlation study. Participants Mother of both male and female children with a documented diagnosis of Cerebral palsy in the age group of 6 months to 3 years. The children in group a received one hour of occupational therapy based on neurodevelopment therapy. Therapy was individualized for each child’s condition and was dictated by the child’s unique clinical needs. The goal of therapy was to improve postural and functional abilities in different developmental position.Each activity was given for 10 15 minutes depending on child’s interest, attention and interaction with the environment. Each session started from the weight bearing activity and gradually followed by performance of the movement within the developmental context.Main Outcome Measures Beck depression inventory Gross motor functional measure Results Table 6 shows that there is a significant difference p 0.05 e in both GMFM AND BDI scores since the p value are 0.000, which is less than the acceptable level of significance of 0.05. Table 7 shows that there is a negative relationship p 0.05 between children current functional level and mother’s depression level.Conclusions From this study it is concluded that there is p 0.05 negative relationship between BDI score and GMFM score. Hence these findings should be used in caution when treating the patients with cerebral palsy. Balvant Kumar Meena | Mr. Subrata Kumar Halder | Ms Smita Jayavant "Depression in Mothers of Children with Cerebral Palsy and Its Relation with Current Functional Status of The Children" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-1 , December 2020, URL: https://www.ijtsrd.com/papers/ijtsrd37912.pdf Paper URL : https://www.ijtsrd.com/medicine/other/37912/depression-in-mothers-of-children-with-cerebral-palsy-and-its-relation-with-current-functional-status-of-the-children/balvant-kumar-meena
President of MSSA Prof. Dr. Vladimir Trajkovski prsented the his topic: "Association between cerebral palsy and autism spectrum disorders" at 8th interdisciplinary congress: "Cerebral palsy and other movement disorders" on 1-2 of November 2018 in Moscow, Russia.
There is Time to Adjust. Aging as a Protective Factor for Autism-Crimson Publ...CrimsonPublishersGGS
There is Time to Adjust. Aging as a Protective Factor for Autism by Diego Iacono in Gerontology & Geriatrics studies
Autism spectrum disorder (ASD) is formally diagnosed before the age of 3 that is, when the central nervous system (CNS) is not yet completely formed, but it is mature enough to generate behavioural abnormalities in some individuals when compared to an age- matched group of typically developed children [1,2]. However, ASD is not a life-threating disease and children diagnosed with ASD age at the same rate as their peers. The possible detrimental or beneficial factors associated with aging in children affected by ASD are not fully known. Surprisingly, the amount of peer-reviewed medical and scientific international literature published on the topic of aging with autism is quite modest and sporadic [3]. The scarcity of aging-ASD investigations derives from the lower level of attention, and related funding opportunities, from the major public and private funding agencies for research across the globe
"Can Treating Visual Problems Improve Attention?" by Dr. Eric Borsting crealcsuf
Presentation for C-REAL's Round Table Hot Topic Series March 2015 Event " Can Treating Visual Problems Improve Attention?" presented by Dr. Eric Borsting.
060915 current research that you should incorporate into yourDominick Maino
Current Research that You Should Incorporate into Your Mode of Practice Now!
Dominick Maino, OD, MEd, FAAO, FCOVD‐A
Moderator
Featuring the Best of AOA's 2015 Poster Presentations
Jun‐27‐2015 8:00AM ‐ 10:00AM
Optic Nerve Head Drusen: A Myriad of Presentations
Jennifer L. Jones, Sylvia E. Sparrow, Christina Grosshans
Validation Study of New LCD‐Based Contrast Sensitivity Testing Method
Sarah Henderson, Jeung H Kim, Paul Harris
Bilateral Cystoid Macular Edema in Retinitis Pigmentosa and its Management
Lindsay T. Gibney
An ODE to Optic Disc Edema
Kelli Theisen
Is Binocular Balancing with Subjective Refraction a thing of the Past?
David Geffen
Optometry's Meeting 2015
Seattle, Washington
During this presentation, Dr. Charlene Sanders and Angi Robinson reviewed topics including the evaluation of study design considerations such as duration of treatment, required assessments, use of placebo, and inclusion of specific age groups; selection of appropriate sites for pediatric trials and the unique needs of these sites; identification of pediatric recruitment/retention hurdles and site specific strategies to overcome these as well as a reflection on ethical concerns related to pediatric research.
School Entry Age: The younger group has more behavior and academic problemsYanki Yazgan
Sule Yazgan, M.D. and I represented our group of child psychiatry, pediatrics and psychology at the AAP 2015 meeting in Wash DC.
Sule presented data from a community based study that was conducted during the 2012-2013 academic year when the compulsory school age entry in Turkey was redefined as 60/66 months.
The study was led by Sebla Gokce, M.D. and I was the senior investigator.
Our findings showed that the 1st grade children who were under 72 months had more behavioral symptoms and functional impairment. There were more diagnosable cases of ADHD in the under 72 months group than the "older" children who became 1st graders after 72 months. The changes in school entry age appears to be associated with more children with ADHD symptoms and impairment in that urban sample.
We need to further elaborate the discussion and do quite a few analyses before we proceed with the write up. The findings are parallel to earlier findings of younger age in the classroom to be associated with more diagnoses of ADHD. Here we have an even younger than usual group whose symptom/impairment level and caseness escalated. Whether these changes in behavior led to an increase in the referrals and treatment for ADHD, and whether this findings is generalizable to more disadvantaged, semiurban and rural areas of Turkey await further research.
Your feedback will be welcome.
International Journal of Humanities and Social Science Invention (IJHSSI) is an international journal intended for professionals and researchers in all fields of Humanities and Social Science. IJHSSI publishes research articles and reviews within the whole field Humanities and Social Science, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Depression in Mothers of Children with Cerebral Palsy and Its Relation with C...ijtsrd
Introduction Cerebral palsy is a condition caused by an abnormality in the brain causing difficulties in movement and coordination, with an onset in the developmental period of childhood. Cerebral palsy can include cerebral malformation arising in the gestational period, a destructive process in the antenatal, prenatal or early postnatal periods, or by various processes acting together. Objective To evaluate the depression level in mothers of children with cerebral palsy and its relation with the current functional status of the children and establish To determine the correlation of functional ability of children with cerebral palsy and depression levels in their mother.Hypothesis There is inversely proportional relationship of depression of mother of children with cerebral palsy with current functional status of their children. There is directly proportional relationship of depression of mother of children with cerebral palsy with current functional status of their children.Design Pre test and post test experimental correlation study. Participants Mother of both male and female children with a documented diagnosis of Cerebral palsy in the age group of 6 months to 3 years. The children in group a received one hour of occupational therapy based on neurodevelopment therapy. Therapy was individualized for each child’s condition and was dictated by the child’s unique clinical needs. The goal of therapy was to improve postural and functional abilities in different developmental position.Each activity was given for 10 15 minutes depending on child’s interest, attention and interaction with the environment. Each session started from the weight bearing activity and gradually followed by performance of the movement within the developmental context.Main Outcome Measures Beck depression inventory Gross motor functional measure Results Table 6 shows that there is a significant difference p 0.05 e in both GMFM AND BDI scores since the p value are 0.000, which is less than the acceptable level of significance of 0.05. Table 7 shows that there is a negative relationship p 0.05 between children current functional level and mother’s depression level.Conclusions From this study it is concluded that there is p 0.05 negative relationship between BDI score and GMFM score. Hence these findings should be used in caution when treating the patients with cerebral palsy. Balvant Kumar Meena | Mr. Subrata Kumar Halder | Ms Smita Jayavant "Depression in Mothers of Children with Cerebral Palsy and Its Relation with Current Functional Status of The Children" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-1 , December 2020, URL: https://www.ijtsrd.com/papers/ijtsrd37912.pdf Paper URL : https://www.ijtsrd.com/medicine/other/37912/depression-in-mothers-of-children-with-cerebral-palsy-and-its-relation-with-current-functional-status-of-the-children/balvant-kumar-meena
President of MSSA Prof. Dr. Vladimir Trajkovski prsented the his topic: "Association between cerebral palsy and autism spectrum disorders" at 8th interdisciplinary congress: "Cerebral palsy and other movement disorders" on 1-2 of November 2018 in Moscow, Russia.
There is Time to Adjust. Aging as a Protective Factor for Autism-Crimson Publ...CrimsonPublishersGGS
There is Time to Adjust. Aging as a Protective Factor for Autism by Diego Iacono in Gerontology & Geriatrics studies
Autism spectrum disorder (ASD) is formally diagnosed before the age of 3 that is, when the central nervous system (CNS) is not yet completely formed, but it is mature enough to generate behavioural abnormalities in some individuals when compared to an age- matched group of typically developed children [1,2]. However, ASD is not a life-threating disease and children diagnosed with ASD age at the same rate as their peers. The possible detrimental or beneficial factors associated with aging in children affected by ASD are not fully known. Surprisingly, the amount of peer-reviewed medical and scientific international literature published on the topic of aging with autism is quite modest and sporadic [3]. The scarcity of aging-ASD investigations derives from the lower level of attention, and related funding opportunities, from the major public and private funding agencies for research across the globe
"Can Treating Visual Problems Improve Attention?" by Dr. Eric Borsting crealcsuf
Presentation for C-REAL's Round Table Hot Topic Series March 2015 Event " Can Treating Visual Problems Improve Attention?" presented by Dr. Eric Borsting.
060915 current research that you should incorporate into yourDominick Maino
Current Research that You Should Incorporate into Your Mode of Practice Now!
Dominick Maino, OD, MEd, FAAO, FCOVD‐A
Moderator
Featuring the Best of AOA's 2015 Poster Presentations
Jun‐27‐2015 8:00AM ‐ 10:00AM
Optic Nerve Head Drusen: A Myriad of Presentations
Jennifer L. Jones, Sylvia E. Sparrow, Christina Grosshans
Validation Study of New LCD‐Based Contrast Sensitivity Testing Method
Sarah Henderson, Jeung H Kim, Paul Harris
Bilateral Cystoid Macular Edema in Retinitis Pigmentosa and its Management
Lindsay T. Gibney
An ODE to Optic Disc Edema
Kelli Theisen
Is Binocular Balancing with Subjective Refraction a thing of the Past?
David Geffen
Optometry's Meeting 2015
Seattle, Washington
During this presentation, Dr. Charlene Sanders and Angi Robinson reviewed topics including the evaluation of study design considerations such as duration of treatment, required assessments, use of placebo, and inclusion of specific age groups; selection of appropriate sites for pediatric trials and the unique needs of these sites; identification of pediatric recruitment/retention hurdles and site specific strategies to overcome these as well as a reflection on ethical concerns related to pediatric research.
Genetics of attention deficit hyperactivity disorder (adhd)Joy Maria Mitchell
Attention deficit hyperactivity disorder (ADHD) is a developmental disorder. ADHD is the commonly studied and
diagnosed as psychiatric disorder. Here we shall see the relation between extraversion and ADHD, neuroticism,
biological relation, Environmental factors and with diagnosis of ADHD. It is known that Genetics is one of the factors
that may contribute to, or exacerbate ADHD. Recent research probing towards the environmental and Genetic factors
causing ADHD differences is the main source for investigation
REVIEWpublished 24 June 2015doi 10.3389fnhum.2015.003.docxmalbert5
REVIEW
published: 24 June 2015
doi: 10.3389/fnhum.2015.00359
Pathophysiology of ADHD and
associated problems—starting points
for NF interventions?
Björn Albrecht*, Henrik Uebel-von Sandersleben, Holger Gevensleben and
Aribert Rothenberger
Department of Child and Adolescent Psychiatry, University Medical Center Göttingen, Göttingen, Germany
Edited by:
Martijn Arns,
Research Institute Brainclinics,
Netherlands
Reviewed by:
Roumen Kirov,
Institute of Neurobiology, Bulgarian
Academy of Sciences, Bulgaria
Leon Kenemans,
Utrecht University, Netherlands
*Correspondence:
Björn Albrecht,
Department of Child and Adolescent
Psychiatry, University Medical Center
Göttingen, von Siebold Straße 5,
37075 Göttingen, Germany
[email protected]
Received: 06 October 2014
Accepted: 02 June 2015
Published: 24 June 2015
Citation:
Albrecht B, Uebel-von Sandersleben
H, Gevensleben H and Rothenberger
A (2015) Pathophysiology of ADHD
and associated problems—starting
points for NF interventions?
Front. Hum. Neurosci. 9:359.
doi: 10.3389/fnhum.2015.00359
Attention deficit hyperactivity disorder (ADHD) is characterized by severe and
age-inappropriate levels of hyperactivity, impulsivity and inattention. ADHD is a
heterogeneous disorder, and the majority of patients show comorbid or associated
problems from other psychiatric disorders. Also, ADHD is associated with cognitive and
motivational problems as well as resting-state abnormalities, associated with impaired
brain activity in distinct neuronal networks. This needs to be considered in a multimodal
treatment, of which neurofeedback (NF) may be a promising component. During NF,
specific brain activity is fed-back using visual or auditory signals, allowing the participants
to gain control over these otherwise unaware neuronal processes. NF may be used
to directly improve underlying neuronal deficits, and/or to establish more general self-
regulatory skills that may be used to compensate behavioral difficulties. The current
manuscript describes pathophysiological characteristics of ADHD, heterogeneity of
ADHD subtypes and gender differences, as well as frequently associated behavioral
problems such as oppositional defiant/conduct or tic disorder. It is discussed how NF
may be helpful as a treatment approach within these contexts.
Keywords: Neurofeedback (NF), ADHD, ODD/CD, tic disorder, comorbidity, children, neurobiology
Introduction
Difficulties with Inattention or Hyperactivity and Impulsivity as the core symptoms of Attention
deficit Hyperactivity disorder (ADHD) are a frequent psychosocial burden. With an early onset
during childhood, ADHD is often persisting throughout life. It is a heterogeneous disorder, and a
challenge to treat. In light of this heterogeneity, the most promising treatment approach should
be multimodal in nature (Taylor et al., 2004; Swanson et al., 2008). Pharmacological interventions
particularly with stimulants such as methylphenidate and amphetamine sulfate, as well as non-
s.
This slide is part of a collection of exam revision slides from Atypical Child Development. The slides have been created by me, and based on several different research papers. The slides were created for essay exam.
Returning genetic research results in neurodevelopmental disorders: report an...KBHN KT
This report originated from discussions at the Annual Brain Development Conference in
late 2013 between researchers in the Neuroethics Core and Autism Spectrum Disorders
Project of NeuroDevNet. Discussants felt that return of research results is a pertinent
issue but that researchers are missing a comprehensive picture of the recommendations,
approaches and empirical data related to the return of research results in genetics studies
in children, in neurodevelopmental disorders, and specifically in autism.
This report provides an overview of recent genetic studies of autism spectrum disorder
(ASD), and reviews the ethical guidance (policies and peer-reviewed literature) and
best practices on the return of individual research results in adult and pediatric genetic
research. We focus on this case because of the wealth of genetic research being
carried out in families and cohorts to explain the etiology of ASD and because there is a
burgeoning literature on parental perspectives on the return of results in this case. The
empirical perspectives are collected and summarized and provide context with regard to
researcher and parent perspectives on the return of genetic results in ASD studies.
We conclude by making recommendations about the return of both incidental and
ASD-related findings and highlight issues that merit further discussion, including the
role of the child or adolescent with developmental disability in decision-making, and
the importance of risk communication. We believe that the report will be of use not only
for those working in the area of ASD but more broadly in the field of pediatric genetic
research and neurodevelopmental disorder research. For example, the publication of new
evidence showing that genetic alterations play an important role in the etiology of cerebral
palsy in some children means that genetic research may becoming increasingly common
in other areas of the study of neurodevelopmental disorders.
An evaluation of the Dore programme. Remarkable success is claimed for this exercise-based treatment that is designed to accelerate cerebellar development. Unfortunately, the published studies are seriously flawed. On measures where control data are available, there is no credible evidence of significant gains in literacy associated with this intervention. There are no published studies on efficacy with the clinical groups for whom the programme is advocated. It is important that family practitioners and paediatricians are aware that the claims made for this expensive treatment are misleading.
A Comparison of Social Cognitive Profiles in children with Aut.docxsleeperharwell
A Comparison of Social Cognitive Profiles in children with Autism
Spectrum Disorders and Attention-Deficit/Hyperactivity
Disorder: A Matter of Quantitative but not Qualitative
Difference?
Carly Demopoulos • Joyce Hopkins •
Amy Davis
Published online: 27 September 2012
� Springer Science+Business Media, LLC 2012
Abstract The aim of this study was to compare social
cognitive profiles of children and adolescents with Autism
Spectrum Disorders (ASD) and ADHD. Participants diag-
nosed with an ASD (n = 137) were compared to partici-
pants with ADHD (n = 436) on tests of facial and vocal
affect recognition, social judgment and problem-solving,
and parent- and teacher-report of social functioning. Both
groups performed significantly worse than the normative
sample on all measures. Although the ASD group had more
severe deficits, the pattern of deficits was surprisingly
similar between groups, suggesting that social cognitive
deficit patterns may be more similar in ASD and ADHD
than previously thought. Thus, like those with ASDs,
individuals with ADHD may also need to be routinely
considered for treatments targeting social skills.
Keywords Autism � ADHD � Social skills � Facial and
vocal affect recognition � Pragmatic judgment � Parent and
teacher report
Introduction
A deficit in social interaction is a defining feature of Aut-
ism Spectrum Disorder (ASD; DSM-IV-TR 2000); how-
ever, social deficits are also a well-documented
phenomenon in children with ADHD (Clark et al. 1999;
Corbett and Constantine 2006; Hattori et al. 2006; Leyfer
et al. 2006; Stormont 2001; Whalen et al. 1990). Indeed,
there is a considerable body of research that has identified
symptom overlap between ADHD and ASD (Corbett and
Constantine 2006; Goldstein and Schwebach 2004; Holt-
mann et al. 2007; Leyfer et al. 2006; Sturm et al. 2004;
Yerys et al. 2009; Yoshida and Uchiyama 2004). It is not
clear, however, if the social deficits in each diagnostic
group differ in quality or degree.
Models of social information processing propose that
receptive social skills (attending to, perceiving, and accu-
rately interpreting relevant social information) are neces-
sary to inform and execute an appropriate social response
(Crick and Dodge 1994; Shapiro et al. 1993). Thus, diffi-
culties at the level of either receptive social skills or
behavioral response could adversely impact a social out-
come. The hierarchical nature of these models implies that
deficits in receptive social skills lead to a suboptimal
behavioral response based upon misunderstanding of the
social context. Alternatively, accurate social perception in
the context of a limited repertoire of appropriate social
problem-solving or response options may result in socially
detrimental behavior as well. Thus, the specific skill defi-
cits (i.e., social comprehension vs. social response) that
lead to inappropriate social behaviors are distinct from
each other and require different i.
Intervento di Peter Sturmey - The Graduate Center and Queens College, City University of New York - "Il trattamento dei disturbi del comportamento e autolesionismo nelle persone con spettro autistico" al preconvegno del "5 Convegno Autismi" organizzato dal Centro Studi Erickson il 14 e 15 ottobre a Rimini.
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
2. I. Berger, H. Cassuto / Journal of Neuroscience Methods 222 (2014) 62–68 63
is commonly nestled with other psychiatric comorbidities, such
as substance abuse, antisocial behaviour, learning disabilities, con-
duct disorders, mood and anxiety disorders (Brown, 2000). Another
common problem of evaluating ADHD in adolescence stems from
typical biases of adolescents in self-reports scales. Adolescents are
considered poor self-observers and often tend to underestimate
their problems (Barkley et al., 1991; Wasserstein, 2005). The agree-
ment between adolescents and their parents regarding the type of
symptoms was found to be low (Rasmussen et al., 2002).
Due to the subjective nature of these instruments, computer-
ized continuous performance tests (CPT) are frequently employed
in clinical and diagnostic settings (Edwards et al., 2007). Typical CPT
task requires the participant to sustain attention over a continuous
stream of stimuli (single letters, shapes or digits which are pre-
sented serially) and to respond to a pre-specified target (Kelip et al.,
1997; Shalev et al., 2011). Traditionally, inattention is assessed in
CPT by the number of omission errors, indicating the number of
times the target was presented, but the participant did not respond,
or by its “inverse” measure calculating relative accuracy (the num-
ber of correct hits out of the total targets presented). Contextual
factors, such as distracting stimuli in the environment, can con-
tribute to increased inattention (Adams et al., 2011; Blakeman,
2000; López-Martín et al., 2013). Therefore, sustained attention can
be broadly characterized as the ability to concentrate on a specific
stimulus over a period of time while excluding distracting stimuli
(Shalev et al., 2011).
Despite the popularity of the CPT in clinical contexts, many
authors have identified concerns about its reliability and validity
in the diagnosis of ADHD.
Test–retest reliability of the CPT varied considerably across
studies. Several CPT’s, such as the Test of Variables of Attention
(T.O.V.A.) (Greenberg and Kindschi, 1998) and the Conners CPT-II
(Conners, 2000) do not report test–retest reliability. In others, such
as the AX’ CPT test, test–retest reliability ranged between 0.14 and
0.94, dependent on CPT indices. Omission errors tend to have the
lower reliability measures while commission errors and response
times have moderate or high measures (Ogundele et al., 2011).
CPT’s are often criticized for their low sensitivity and specificity
rates (less than 70%) (Edwards et al., 2007; McGee et al., 2000; Riccio
et al., 2001; Skounti et al., 2007). Many authors have questioned
its ability to consistently discriminate ADHD children from normal
controls, psychiatric controls or learning disabilities (DeShazo et al.,
2001; Dickerson Mayes et al., 2001; Ogundele et al., 2011; Schachar
et al., 1998; Skounti et al., 2007). Others reported a weak associa-
tion between CPT performance and behavioural indices of ADHD
(Christensen and Joschko, 2001; Epstein et al., 2009; McGee et al.,
2000).
The validity of the CPT in the diagnosis of ADHD is even
more controversial among teenagers (Robin, 1998). The Degraded
Stimulus Continuous Performance Test (DS-CPT) was found to be
insensitive to identifying sustained attention deficits in adolescent
populations and failed to discriminate ADHD from controls (Rund
et al., 1998). Similarly, Rucklidge (2006) reported that the Conners
CPT-II (Conners, 2000) failed to identify many adolescents with
ADHD, and was generally more sensitive to ADHD in males than in
females. Recently, Diamond et al. (2012) have demonstrated that
the correlation between neurologist’s impression of the presence
of attention deficit and the T.O.V.A. scores was weaker in ado-
lescents (ages 13–18) than in younger children (ages 6–12). The
Gordon Diagnostic System (GDS; Gordon and Mettelman, 1987),
which is the only CPT that has been researched specifically with
adolescents (also approved by the FDA), successfully discriminated
ADHD adolescents from controls on the vigilance task, but not on
the distractibility task (Robin, 1998).
Barkley (1991) has shown low correlations between CPT perfor-
mance of adolescents and other measures of ADHD such as parents
and teachers rating scales. It was suggested that the ecological
validity of the CPT in adolescent samples is weaker than in younger
children and that this shortcoming is crucial where prediction to
school behaviour may be desired. Barkley (1991) emphasized the
need to improve the ecological validity of the CPT by evaluating
the child’s behaviour in more natural settings. Nevertheless, even
when noise-generated CPT was employed (Uno et al., 2006), the
sensitivity of the test to ADHD in older children (ages 10–12) was
lower than in younger children (ages 7–9). The authors suggested
that the differences in attention span between ADHD and normal
controls are reduced to a level undetectable by CPT, as a result of
developmental changes.
Another possible explanation for the insensitivity of CPT in
adolescents is the constant pace of stimuli presentation. Because
the inter-stimulus interval in traditional CPT is typically fixed, it
makes the task too easy for adolescents who quickly figure out the
timing of stimulus appearance (Robin, 1998). Further support for
the ceiling effect in CPT performance of adolescents arrives from
imaging study that compared brain activation patterns in adoles-
cents with and without ADHD while performing an attentional
CPT (Epstein et al., 2009). The two groups performed similarly and
activated similar regions during performance, but children with
ADHD appear to maintain the use of right prefrontal regions beyond
what is observed among normal controls. The difficulty to detect
group behavioural differences was attributed to the low cognitive
demands of the task. Taken together, these findings suggest that
conventional CPT’s may fail to consistently distinguish ADHD from
non-ADHD teenagers due to insufficient cognitive demands and
may not reflect the conditions in school.
The aim of this study was to explore whether the incorporation
of environmental distractors into a CPT would increase its ability to
distinguish ADHD adolescents from controls (ages 13–18). Assum-
ing that distracting stimuli have an effect on sustained attention by
increasing the rate of omission errors in CPT, we hypothesized that
adolescents with ADHD would perform significantly more omission
errors than their non-ADHD peers in the presence of distracting
stimuli. We also examined which type of distractors would be more
effective in terms of ADHD diagnosis.
2. Methods
2.1. Participants
Participants were 176 adolescents aged 13–18 years, 118 were
boys and 58 girls. The clinical ADHD group was composed of 133
participants previously diagnosed with ADHD (Mean age = 14.64,
S.D. = 1.43), and the control group included 43 participants without
ADHD (Mean age = 15.08, S.D. = 1.71).
Participants in the ADHD group were recruited from adolescents
referred to the out-patient clinics of a Neuro-Cognitive Centre,
based in a tertiary care university hospital. The referrals to the
centre were made by paediatrician, general practitioner, teacher,
psychologist, or parents.
The following were the inclusion criteria for participants in the
ADHD group.
Each participant met the criteria for ADHD according to DSM-
IV-TR criteria [American Psychiatric Association (APA), 2000],
as assessed by a certified paediatric neurologist. The diagnostic
procedure included completion of a semi-structured interview
(adolescent and parents) fulfilling the diagnostic guidelines as
described in the clinical practice guideline for the diagnosis, eval-
uation, and treatment of ADHD in children and adolescents by
the American Academy of Paediatrics (Wolraich et al., 2011) and
mandatory rating scales for home and school (DuPaul et al., 1998),
as well as medical/neurological examination.
3. 64 I. Berger, H. Cassuto / Journal of Neuroscience Methods 222 (2014) 62–68
Fig. 1. Definition of the time line – target and non-target stimuli were presented for 500, 1000 or 4000 ms. Each stimulus was followed by a void period of the same duration.
The stimulus remained on the screen for the full duration regardless the response. Distracting stimuli were not synchronized with target/non-target’s onset and could be
generated during target/non target stimulus or during the void period.
Participants in the control group were randomly recruited from
regular school classes. The inclusion criteria for participants in
the control group were: (1) score below the clinical cut off point
for ADHD symptoms on ADHD/DSM-IV Scales (APA, 2000; DuPaul
et al., 1998) and (2) absence of academic or behavioural problems
based on parents and teachers reports. For this purpose the parents
and teachers were asked to state (with the informed consent) that
there are no behavioural/academic/social difficulties. Given these
conditions, no additional physical/neurological examination was
administered.
Assigning participants to ADHD/non-ADHD groups based on
parents and teachers ratings of ADHD symptoms is a common and
reliable method in the literature (e.g., Berwid et al., 2005; Uno et al.,
2006; Van Mourik et al., 2007).
Exclusion criteria for all participants were: abnormal mental
ability, other chronic (mental, health or developmental) condition,
chronic use of medications, and primary psychiatric diagnosis (e.g.,
depression, anxiety, or psychosis). Since we worked in Jerusalem,
our population was extremely heterogeneous, multicultural, and
included a spectrum of families with regard to potentially con-
founding factors correlated with the diagnosis of ADHD (Wolraich
et al., 2011). All participants agreed to participate in the study and
their parents provided a written informed consent to the study,
approved by the Helsinki committee (IRB) of Hadassah-Hebrew
University Medical Centre Jerusalem, Israel.
2.2. Measures
Measurement of adolescent behaviour – the parent and teacher
forms of the ADHD/DSM-IV scales were used to assess the level of
participants’ ADHD behaviours (APA, 2000; DuPaul et al., 1998).
The MOXO Continuous Performance Test – the study employed
the MOXO-CPT version1 (Berger and Goldzweig, 2010), which is
a standardized computerized test designed to diagnose ADHD
related symptoms. The test included visual and auditory stimuli
that serve as distractors.
The total duration of the test was 18.2 min, and it is composed
of eight levels (136.5 s, 59 trials each). In each trial a stimulus
(target/non-target) was presented for 500, 1000 or 4000 milli-
seconds and then followed by a “void” period of the same duration
1
The term ‘MOXO’ derives from the world of Japanese martial arts and means a
‘moment of lucidity’. It refers to the moments preceding the fight, when the warrior
clears his mind from distracting, unwanted thoughts, and feelings.
(Fig. 1). The stimulus remained on the screen for the full duration no
matter if a response was produced. This practice allowed the mea-
suring of response timing (whether the response occurred during
stimulus presentation or the void period) as well as the accuracy of
the response.
In each level 34 target and 25 non-target stimuli were presented.
Both target and non-target stimuli were cartoon pictures that do
not include any letters. The absence of letters is important given
the fact that ADHD patients tend to have learning difficulties (e.g.,
dyslexia, dyscalculia) that may be confound with CPT performance
(Seidman et al., 2001). The stimuli were presented sequentially in
the middle of a computer screen and the participant was instructed
to respond as quickly as possible to target stimuli by pressing the
space bar once, and only once. The participant was also instructed
not to respond to any other stimuli except the target, and not to
press any other key but the space bar.
Test level and distracting stimuli-In order to simulate everyday
environment of adolescents, the MOXO-CPT contained distracting
stimuli. This feature is unique to this specific CPT. Distractors were
short animated video clips containing visual and auditory features
which can appear separately or together. This enabled to present
three types of distractions that characterize everyday environment:
(a) visual distractors (e.g., animated barking dog); (b) auditory dis-
tractors (e.g., barking sound); and (c) combination of both visual
and auditory distractors (e.g., animated barking dog with the sound
of barking).
Overall, eight different distractors were included, each of them
could appear as pure visual, pure auditory or as a combination
of them. Different levels of the MOXO-CPT were characterized by
a different set of distractors: levels 1 and 8 did not include any
distractors but only target and non-target stimuli, levels 2 and 3
contained pure visual stimuli, levels 4 and 5 contained pure audi-
tory stimuli, and levels 6 and 7 contained a combination of visual
and auditory stimuli. Each distractor was presented for 8 s, with a
fixed interval of 0.5 s between two distractors. Distractors’ onset
was not synchronized with target/non-target’s onset and could be
generated during target/non target stimulus or during the void
period.
Visual distractors appeared at one of four spatial locations on
the sides of the screen: down, up, left or right. The sequence of
distractors and their exact position on the display were constant
for each level. The burden of the distracting stimuli increased at the
odd number levels; in the 2nd, 4th, and 6th level only one distractor
was presented at a time, while in the 3rd, 5th, and 7th level two
distractors were presented simultaneously.
4. I. Berger, H. Cassuto / Journal of Neuroscience Methods 222 (2014) 62–68 65
Table 1
Differences in omission errors between ADHD and non-ADHD adolescents.
Distractors type ADHD (N = 143) Non-ADHD (N = 33) Difference t(172)
M S.D. M S.D.
No distractors 2.17 0.44 0.58 1.22 4.51, p < 0.05
Visual distractors 3.56 3.24 1.02 2.09 4.61, p < 0.001
Auditory distractors 2.46 2.95 0.81 2.14 3.17, p < 0.05
Combination of visual and auditory distractors 3.92 3.49 0.88 2.45 5.13, p < 0.001
M = mean; S.D. = standard deviation.
Performance indices – the MOXO-CPT included four perfor-
mance indices: attention, timing, impulsivity, and hyperactivity.
For detailed description of performance indices see Supplementary
A.
2.3. Procedure
In the current study, the test was administered by a technician
who made sure that the participant understood the instructions.
The technician was present throughout the entire session. All
participants (including the ADHD group) were drug naïve (not med-
icated at all) before and during their participation in the study.
2.4. Data analyses
All analyses were conducted with SAS software for Windows
version 9.2.
A p-value of ≤0.05 was considered statistically significant. First,
Chi-square analysis and t-test for unpaired samples were used to
examine group differences in background variables. Second, effects
of background variables, ADHD, and test level on omission errors
were examined through a Linear Repeated Measures model with
Tukey’s correction for multiple comparisons. Omission errors were
the dependant variable, whereas age, gender, group, level, and
level × group interaction were the independent variables. Between
and within group effects were measured in every CPT condition (no
distractors, visual distractors, auditory distractors and a combina-
tion of visual and auditory distractors). For this purpose, every two
identical levels were combined: levels 1 and 8 (no distractors), lev-
els 2 and 3 (visual distractors), levels 4 and 5 (auditory distractors)
and levels 6 and 7 (combination of visual and auditory distractors).
To determine which type of distractors was more useful in terms
of ADHD diagnosis, we calculated the areas under the receiver oper-
ating characteristic (ROC) curves. After a ROC was generated for
each distractor type, chi-square tests were performed in order to
compare the utility of different test conditions in the diagnosis of
ADHD.
3. Results
3.1. Effects of distractors on omission errors in ADHD and
non-ADHD adolescents
In order to study the added value of the incorporation of dis-
tractors in the CPT for a better differentiation between ADHD and
controls a linear repeated measures model with Tukey’s correction
for multiple comparisons was conducted.
This model included: (a) between groups analysis of the differ-
ences in the rate of omission errors between ADHD and non-ADHD
adolescents and (b) within-group analysis of the differences in
omission errors between no distractors conditions and the three
conditions which contained distractors (visual, auditory and a com-
bination of them). First, analyses showed that both gender [F(1,
172) = 5.26, p < 0.05] and age [F(1, 172) = 9.10, p < 0.01] were asso-
ciated with CPT performance. That is, boys and younger children
demonstrated higher omission errors. However, ADHD group did
not differ from the non-ADHD group in age [t(174) = 1.48, p = 0.097]
or gender distributions [ 2(1, N = 176) = 0.19, p = 0.662].
When controlling for age and gender, group affiliation had a
significant effect on the rate of omission errors [F(1, 172) = 28.45,
p < 0.001]. As can be seen in Table 1, ADHD adolescents demon-
strated higher rate of omission errors than their unaffected peers
in all CPT conditions (no distractors, visual distractors, auditory dis-
tractors and a combination of visual and auditory distractors). Most
importantly, group × level interaction revealed that the difference
between the two groups varied as a function of task demands
[F(3, 172) = 4.98, p < 0.01]. Within-groups analysis indicated that in
the ADHD group, omission errors were significantly higher in the
presence of visual distractors and the combination of visual and
auditory distractors than in no-distractors conditions. The pres-
ence of pure auditory distractors did not increase the amount of
omission errors as compared to no-distractors. In the control group,
distracting stimuli had no effect on CPT performance as compared
to no-distractors conditions (Table 2).
3.2. ROC analyses
The discriminant ability of different distractors types was eval-
uated by a Receiver Operating Characteristic (ROC) curve analysis
(Fig. 2). ROC analysis summarizes diagnostic efficiency with the
area under the curve (AUC) statistic.
First, ROC analyses revealed that the mere presence of dis-
tractors (AUC = 0.890) significantly improved the AUC of the test,
as compared to the absence of distractors (AUC = 0.784) [ 2(1,
N = 176) = 8.51, p < 0.01]. Specifically, the AUC of combined visual
and auditory distractors was the highest (AUC = 0.867). The com-
bination of distractors significantly improved the utility of the
test in the diagnosis of ADHD as compared to no-distractors
[ 2(1, N = 176) = 5.35, p < 0.05]. Pure visual (AUC = 0.846) and pure
auditory (AUC = 0.772) distractors did not yield any diagnostic
Table 2
Level Differences in omission errors within each study group.
Comparison t(172) ADHD (N = 143) Non-ADHD (N = 33)
No distractors vs. visual distractors −6.59, p < 0.0001 −1.20, N.S.
No distractors vs. auditory distractors −1.30, N.S. −0.60, N.S.
No distractors vs. combined distractors −6.65, p < 0.0001 −0.65, N.S.
Visual distractors vs. auditory distractors 5.70, p < 0.0001 0.62, N.S.
Visual distractors vs. combined distractors −1.40, N.S. 0.30, N.S.
Auditory distractors vs. combined distractors −6.12, p < 0.0001 −0.17, N.S.
5. 66 I. Berger, H. Cassuto / Journal of Neuroscience Methods 222 (2014) 62–68
Fig. 2. ROC analyses.
advantage over no-distractors conditions. Although the combina-
tion of visual and auditory distractors was favourable in terms of
sensitivity and specificity in comparison to pure auditory distrac-
tors [ 2(1, N = 176) = 12.92, p < 0.001], it was not beneficial over
pure visual distractors [ 2(1, N = 176) = 0.64, N.S.].
4. Discussion
This study investigated the effects of environmental distractors
on sustained attention of ADHD and non-ADHD adolescents (ages
13–18). Results showed that ADHD adolescents demonstrated
higher rates of omission errors than their unaffected peers in all CPT
conditions. In addition, ADHD adolescents produced significantly
more omission errors in the presence of pure visual distractors
and the combination of visual and auditory distractors than in
no-distractors conditions. In contrast, distracting stimuli had no
effect on CPT performance of non-ADHD adolescents. Findings from
ROC analysis further demonstrated that independently of distrac-
tors type, impending distractors in CPT significantly improved the
sensitivity and specificity of the test.
It is known that a variety of visual and auditory stimuli exists
in the everyday environment of ADHD children and that prob-
lematic behaviour first appear in the presence of such stimuli.
Thus, our results support the idea that ADHD is indeed marked by
high distractibility and that teenagers with ADHD have difficulties
to sustain attention in the presence of irrelevant environmental
stimuli. These findings are in line with studies of younger chil-
dren with ADHD, which demonstrated high distractibility during
CPT and non-CPT tasks (Adams et al., 2011; Gumenyuk et al.,
2005; Parsons et al., 2007; Pelham et al., 2011). Parsons et al.
(2007), who used a virtual reality technology to simulate every-
day distractibility in ADHD, have shown that during distracting
conditions, ADHD children were more hyperactive and produced
more omission errors on the Conners’ CPT-II as compared to non-
ADHD children. On the other hand, our findings are inconsistent
with other studies which indicated that auditory and visual distrac-
tors did not impair cognitive performance of ADHD children or even
improved it (Abikoff et al., 1996; Uno et al., 2006; Van Mourik et al.,
2007). This diversity may result from the type of distractors used.
While some studies have used neutral stimuli (neutral tone/letter)
as distractors (Gordon and Mettelman, 1987; Uno et al., 2006;
Van Mourik et al., 2007), the MOXO-CPT used more ecologically
valid stimuli that are typically found in the child’s environment.
Since ADHD children have more difficulties in filtering meaningful
distractors (Blakeman, 2000) they may fail to inhibit response to
relevant, everyday stimuli rather than to neutral information.
Another factor that may contribute to the high distractibility
of ADHD adolescents in this study is the method of distractors
presentation. In several studies, auditory distractors served as a
background noise while children performed another cognitive task
(Abikoff et al., 1996; Pelham et al., 2011). In contrast, distractors in
the MOXO-CPT vary in their type, in their length of presentation and
in their location on the screen. This mode of presentation did not
allow adjustment or de-sensitization to the distractors, therefore
kept them salient.
The current study revealed that the distractibility of ADHD ado-
lescents varied across the distractors’ modality. The fact that visual
stimuli appeared as more potent distractors for ADHD adolescents
than auditory distractors is consistent across studies with ADHD
children (Pelham et al., 2011). The most straightforward hypothe-
sis is that because the MOXO-CPT is a visual task that includes visual
input and processing, it might be more vulnerable to visual distrac-
tors that use the same cognitive modality (Wickens, 1984, 2002).
It is also possible that due to impaired visual attention in ADHD
(Kofler et al., 2008), additional visual information easily overload
the cognitive/physiological system, thus interfering with perfor-
mance (Armstrong, 1993; Armstrong and Greenberg, 1990).
The effect of auditory distractors on ADHD children and adoles-
cent remains unclear. While the current study failed to show any
effect of auditory distractors on cognitive performance in ADHD
adolescents, others have found that auditory distractors could
either interfere or improve it (Abikoff et al., 1996; Pelham et al.,
2011; Söderlund et al., 2007). Uno et al. (2006) who specifically
tested the effect of auditory noise on CPT performance, found that
ADHD children produced fewer omission errors in the presence of
auditory noise than in the no-noise condition. The positive effect of
distracting auditory stimuli on the cognitive performance of ADHD
patients is usually attributed to the increased arousal provoked
by a novel signal (Uno et al., 2006; Van Mourik et al., 2007). It is
possible that distractors in the MOXO-CPT failed to improve atten-
tion in ADHD adolescents because of the little information they
conveyed for the participant. It has been suggested (Parmentier
et al., 2010) that the degree to which a novel, unexpected auditory
sound may optimize performance depends on the amount of infor-
mation it conveys. When a novel sound predicts another relevant
stimulus, the system can take advantage of the auditory distrac-
tors to improve its functioning. In contrast to other CPT (Uno et al.,
2006; Van Mourik et al., 2007) distractors in the MOXO-CPT did
not precede the target or were generated stimulatingly with it,
but rather were unsynchronized with it. This fact may lower the
extent to which the sound included information necessary to opti-
mize performance and may explain why auditory distractors did
not improve sustained attention in our study.
Several limitation of this study should be considered. First, par-
ticipation in the study was based on a voluntary agreement of
children and their parents. This self-selected sampling strategy
tends to be biased towards favouring more cooperative and moti-
vated individuals. Therefore, it is impossible to determine whether
this sample also represents other children that were not recruited
and whether cooperation is confounded with ADHD variables. This
limitation is typical to most clinic-based ADHD studies around the
world (Gau et al., 2010; Lee and Ousley, 2006). In addition, the
clinics from which ADHD children were recruited were based in
6. I. Berger, H. Cassuto / Journal of Neuroscience Methods 222 (2014) 62–68 67
tertiary care hospital. This population has heterogeneous back-
ground characteristics including those correlates of ADHD. Finally,
the exclusion of ADHD children with severe comorbidities may
limit the generalization of our results.
Overall, our findings showed that independently of distractor
type, ADHD teenagers were more distracted than healthy con-
trols during CPT performance, ADHD adolescents produced more
omission errors in the presence of visual environmental stimuli or
the combination of visual and auditory stimuli in comparison to
no-distractors conditions. In terms of ADHD diagnosis, the mere
presence of distractors improved the utility of the test relative to
no distractors.
Visual environmental stimuli emerged as better distractors than
auditory ones and combining visual and auditory distractors was
not beneficial in terms of validity, as compared to pure visual dis-
tractors.
In contrast to the majority of cognitive tasks, distracting stimuli
in the MOXO-CPT were external to the task (i.e., not conflicting
with task demands). The fact that adolescents with ADHD were
distracted by external stimuli suggests that in everyday life these
individuals may be more distracted by irrelevant stimuli in the
classroom (e.g., someone talks in the next room) rather than back-
ground stimuli (e.g., music) or distractors that are part of the
cognitive task. Hence, reducing irrelevant environmental stimuli
or learning how to regulate their influence on attention functions,
may assist adolescents with ADHD in coping with distractibility
problems.
Finally, this study lends further support for using the CPT as an
aiding tool in the diagnosis of ADHD in teenagers, once employ-
ing appropriate task demands that better simulate distractibility in
everyday life.
Future research should address the diagnostic utility of the test
in larger spectrum of age and in different populations (e.g., ADHD
with comorbid features).
Another question that should be further explored is how dis-
tractibility is marked in different subtypes of ADHD. Previous
studies examining ADHD subtype differences in neuropsycholo-
gical functioning are limited and inconsistent (Booth et al., 2007;
Lockwood et al., 2001; Nikolas and Nigg, 2013; Schwenck et al.,
2009) It has been long debated whether one category is capa-
ble to describe the high heterogeneity in symptom presentation
and impairments of ADHD (Nigg et al., 2010). Moreover, it is still
unclear whether different ADHD subtypes reflect unique configura-
tions of the syndrome or simply various degrees of behavioural and
neuropsychological weaknesses (Nikolas and Nigg, 2013). Thus,
it would be highly important to examine if specific subtypes of
ADHD are more distracted than others (Keage et al., 2006; Mayes
et al., 2009). While some authors suggested that distractibility
relates to difficulty in response inhibition (Oades et al., 2002)
and therefore characterizes ADHD predominantly hyperactive and
combined subtypes (Carlson and Mann, 2000; Lahey et al., 1997),
others proposed that distractibility has more to do with inattentive-
ness problems, hence is more expected in ADHD predominantly
inattentive subtype (McBurnett et al., 2001; Milich et al., 2001).
It is a purpose of future research, and beyond the scope of this
study, to explore the neuropsychological correlates of distractibility
in CPT and how they are pronounced in different ADHD sub-
types. Although the current study points out a potential association
between distractibility and inattention, the effect of distractors on
other CPT measures (e.g., commission errors) is equally important.
Conflicts of interest statement
Itai Berger serves in the scientific advisory board to Neuro-Tech
Solutions Ltd. Hanoch Cassuto declared no potential conflicts of
interest with respect to this study.
Acknowledgments
The authors wish to thank Dr. Ortal Slobodin for her efficient
help and skills and to Merav Aboud and Julia Melamed for their kind
and professional attitude towards the participating adolescents and
their families.
Appendix A. Supplementary data
Supplementary data associated with this article can be found,
in the online version, at http://dx.doi.org/10.1016/j.jneumeth.
2013.10.012.
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