1) According to research, genetics play an important role in ADHD, with heritability estimates between 60-90% from twin and adoption studies. However, genome-wide association studies have not found significant genetic associations, suggesting the genetic factors are complex.
2) Prenatal factors like maternal smoking and stress during pregnancy increase the risk of ADHD in children. Perinatal risks like low birth weight and preterm birth are also associated with higher ADHD risk.
3) Various environmental exposures have been linked to ADHD, including lead, PCBs, pesticides, and certain food dyes and additives which some studies have found can exacerbate ADHD symptoms.
4) However
Genetics of attention deficit hyperactivity disorder (adhd)Joy Maria Mitchell
Attention deficit hyperactivity disorder (ADHD) is a developmental disorder. ADHD is the commonly studied and
diagnosed as psychiatric disorder. Here we shall see the relation between extraversion and ADHD, neuroticism,
biological relation, Environmental factors and with diagnosis of ADHD. It is known that Genetics is one of the factors
that may contribute to, or exacerbate ADHD. Recent research probing towards the environmental and Genetic factors
causing ADHD differences is the main source for investigation
DSM proposal for Sensory Processing Disorder. Of interest to those who want to know more in general, or know more about SPD as it compares to ASD or Misophonia.
Genetics of attention deficit hyperactivity disorder (adhd)Joy Maria Mitchell
Attention deficit hyperactivity disorder (ADHD) is a developmental disorder. ADHD is the commonly studied and
diagnosed as psychiatric disorder. Here we shall see the relation between extraversion and ADHD, neuroticism,
biological relation, Environmental factors and with diagnosis of ADHD. It is known that Genetics is one of the factors
that may contribute to, or exacerbate ADHD. Recent research probing towards the environmental and Genetic factors
causing ADHD differences is the main source for investigation
DSM proposal for Sensory Processing Disorder. Of interest to those who want to know more in general, or know more about SPD as it compares to ASD or Misophonia.
Prenatal alcohol exposure and offspring mental health: A systematic reviewBARRY STANLEY 2 fasd
A B S T R A C T
Background: High levels of alcohol use in pregnancy have been shown to be associated with negative physical health consequences in offspring. However, the literature is less clear on the association of alcohol use in pregnancy and offspring mental health, specifically for low levels of prenatal alcohol exposure. We conducted a systematic review to evaluate studies examining this association.
Methods: Studies were identified by searching PsycINFO, PubMed and Web of Science, and were included if they examined alcohol use during pregnancy as an exposure and offspring mental health at age 3 or older as an outcome. We excluded non-English language publications and studies of fetal alcohol syndrome.
Results: Thirty-three studies were included and were categorized by mental health outcomes: anxiety/depression, emotional problems, total internalizing problems, total problem score, and conduct disorder. Over half of the analyses reported a positive association of prenatal alcohol exposure and offspring mental health problems.
Conclusions: Our review suggests that maternal alcohol use during pregnancy is associated with offspring mental health problems, even at low to moderate levels of alcohol use. Future investigation using methods that allow stronger causal inference is needed to further investigate if these associations shown are causal.
The utility of psychotropic drugs on patients with fetal alcohol spectrum dis...BARRY STANLEY 2 fasd
ABSTRACT
BACKGROUND: Treatment of the complications arising from Prenatal Alcohol Exposure (PAE) has largely been focused on psychosocial and environmental approaches. Research on the
use of medications, especially psychotropic medications, has lagged behind.
OBJECTIVES: This systematic review sought to investigate psychotropic medication related findings and outcomes in those diagnosed with Fetal Alcohol Spectrum Disorder (FASD).
METHODS: Comprehensive searches were conducted in seven major databases (Medline/
PubMed, Scopus, Web of Knowledge, Embase, PsycINFO, Cochrane Library, and
PsycARTICLES) up to February 2017. Key search terms with synonyms were mapped on these databases. There were no timeline restrictions and no grey literature searches. Two reviewers
independently assessed 25 studies that met the inclusion criteria. Most studies were reviews of treatment and retrospective case series.
RESULTS: Two crossover randomized trials were reported, and the findings were not amenable to meta-analysis. Several conditions (depression, agitation, seizures, and outburst) combined with the most frequent presentation, ADHD, to represent the rationale for prescribing psychotropic medications. Second-generation antipsychotics were found to improve social skills, but the paucity of data limited the extent of clinical guidance necessary for the field.
CONCLUSIONS: The systematic review showed that there are some clinical evidence displaying
the validity of psychopharmacological interventions in people with FASD, which varies across the spectrum of disease severity, age, and gender. There is a need for more clinical evidencebased studies in addition to clinical expert opinions to substantiate an optimal ground for individualized management of FASD.
The study protocol for this review was registered in PROSPERO with registration number
CRD42016045703
Asperger syndrome in childhood personality dimensions in adult lifemiriam odar
Study about to examine temperament and character in males that were diagnosed with ASD in childhood and followed prospectively over almost two decades.
Childhood Maltreatment and PTSD Literature Review and Proposed StudyAlexandraPerkins5
This literature and proposed study explores several research articles relating to childhood maltreatment and PTSD. The second section proposes a hypothetical study to further explore a gap identified in the literature review.
Presentatie autisme escap 2015m4 madrid how_malleable_is_autism_escap_postUtrecht
KEYNOTE abstract by professor Sally Rogers (UC Davis MIND Institute, Sacramento) titled 'How malleable is autism? Outcome studies from the youngest children with ASD', held at the ESCAP 2015 Congress in Madrid, Monday June 22nd 2015
Relationship of Attention Deficit Hyperactivity Disorder with Substance AbuseHafiz Saad Salman
The attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders affecting 3% to 6% of children1 and almost 5% of adults2. Across population, Prevalence rates vary from 2.2% to 16.1% in clinical versus community cohorts. Its frequency has been reported as high as 34% ADHD in clinical setting in Pakistan3. There was a myth for many years that the disorder remits during adolescence, but it is now well established that it can be experienced by a patient in adulthood as well. There is a bidirectional overlap between ADHD and drug abuse and dependence4 and affect 27% of adult population5. The co-occurrence of ADHD and addiction is very common. Previous studies have shown that adults with ADHD are a risk for substance use disorder (SUD) and almost 52% of adult had a lifetime history of SUD2, 3. The co-morbidity between ADHD and SU shows relativity and relevant to research and clinical development in psychiatry, pediatrics and psychology5. The diagnosing and specific risk factor associated with SU within ADHD may lead to a better targeted pharmacotherapy and psychotherapeutic treatments for both the disorders upon expression at early stage of their lives7, 8. Higher rates of ADHD have been reported in patients having SUD relative to controls9, 10. 15% to 25% adults with SUD history have been estimated to have ADHD9. Studies have conducted in juvenile adolescents for assessing ADHD and other disorders in substance abusing groups had overrepresentation of ADHD10, 11. ADHD predominates from 15% to 25% in individuals with SUD12, 13. Two studies showed that the 24% of 201 inpatients14 and 10% cocaine abusers for drug detoxification treatment had ADHD15. The treatment of ADHD is usually done with stimulants like methylphenidate, amphetamine etc., with the behavioral therapy of the patient and family counseling.
SparksDuncan2013: Outside the Black Box: Re-assessing Pediatric Antidepressan...Barry Duncan
Sparks, J., & Duncan, B. (2013). Outside the black box: Re-assessing pediatric antidepressant prescription. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 22, 240-256.
Objective: The purpose of this review is to assess whether evidence supports a favorable risk/benefit profile for pediatric antidepressant use and reconsideration of the black box. Method: The review examines studies post-black box purporting to show declines in pediatric antidepressant use and rising youth suicide, summarizes evidence for efficacy and safety of pediatric antidepressants, and discusses irregularities in recent meta-analyses of fluoxetine for youth. Results: Pediatric antidepressant prescription did not significantly decline post-black box and youth suicide has risen only in recent years. Recent meta-analyses fail to undermine evidence that antidepressants are associated with increased risk of suicidality in youth. Conclusions: First line prescription of antidepressants for youth is not advisable. The black box and international warnings on pediatric use of antidepressants are warranted. Wider availability of psychosocial options for depressed youth is recommended.
KEYNOTE presentation (June 2015), ESCAP Expert Paper (July 2015), TV interview and abstract by professor Beate Herpertz-Dahlmann (Aachen University) on new developments in the diagnostics and treatment of adolescent eating disorders
Prenatal alcohol exposure and offspring mental health: A systematic reviewBARRY STANLEY 2 fasd
A B S T R A C T
Background: High levels of alcohol use in pregnancy have been shown to be associated with negative physical health consequences in offspring. However, the literature is less clear on the association of alcohol use in pregnancy and offspring mental health, specifically for low levels of prenatal alcohol exposure. We conducted a systematic review to evaluate studies examining this association.
Methods: Studies were identified by searching PsycINFO, PubMed and Web of Science, and were included if they examined alcohol use during pregnancy as an exposure and offspring mental health at age 3 or older as an outcome. We excluded non-English language publications and studies of fetal alcohol syndrome.
Results: Thirty-three studies were included and were categorized by mental health outcomes: anxiety/depression, emotional problems, total internalizing problems, total problem score, and conduct disorder. Over half of the analyses reported a positive association of prenatal alcohol exposure and offspring mental health problems.
Conclusions: Our review suggests that maternal alcohol use during pregnancy is associated with offspring mental health problems, even at low to moderate levels of alcohol use. Future investigation using methods that allow stronger causal inference is needed to further investigate if these associations shown are causal.
The utility of psychotropic drugs on patients with fetal alcohol spectrum dis...BARRY STANLEY 2 fasd
ABSTRACT
BACKGROUND: Treatment of the complications arising from Prenatal Alcohol Exposure (PAE) has largely been focused on psychosocial and environmental approaches. Research on the
use of medications, especially psychotropic medications, has lagged behind.
OBJECTIVES: This systematic review sought to investigate psychotropic medication related findings and outcomes in those diagnosed with Fetal Alcohol Spectrum Disorder (FASD).
METHODS: Comprehensive searches were conducted in seven major databases (Medline/
PubMed, Scopus, Web of Knowledge, Embase, PsycINFO, Cochrane Library, and
PsycARTICLES) up to February 2017. Key search terms with synonyms were mapped on these databases. There were no timeline restrictions and no grey literature searches. Two reviewers
independently assessed 25 studies that met the inclusion criteria. Most studies were reviews of treatment and retrospective case series.
RESULTS: Two crossover randomized trials were reported, and the findings were not amenable to meta-analysis. Several conditions (depression, agitation, seizures, and outburst) combined with the most frequent presentation, ADHD, to represent the rationale for prescribing psychotropic medications. Second-generation antipsychotics were found to improve social skills, but the paucity of data limited the extent of clinical guidance necessary for the field.
CONCLUSIONS: The systematic review showed that there are some clinical evidence displaying
the validity of psychopharmacological interventions in people with FASD, which varies across the spectrum of disease severity, age, and gender. There is a need for more clinical evidencebased studies in addition to clinical expert opinions to substantiate an optimal ground for individualized management of FASD.
The study protocol for this review was registered in PROSPERO with registration number
CRD42016045703
Asperger syndrome in childhood personality dimensions in adult lifemiriam odar
Study about to examine temperament and character in males that were diagnosed with ASD in childhood and followed prospectively over almost two decades.
Childhood Maltreatment and PTSD Literature Review and Proposed StudyAlexandraPerkins5
This literature and proposed study explores several research articles relating to childhood maltreatment and PTSD. The second section proposes a hypothetical study to further explore a gap identified in the literature review.
Presentatie autisme escap 2015m4 madrid how_malleable_is_autism_escap_postUtrecht
KEYNOTE abstract by professor Sally Rogers (UC Davis MIND Institute, Sacramento) titled 'How malleable is autism? Outcome studies from the youngest children with ASD', held at the ESCAP 2015 Congress in Madrid, Monday June 22nd 2015
Relationship of Attention Deficit Hyperactivity Disorder with Substance AbuseHafiz Saad Salman
The attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders affecting 3% to 6% of children1 and almost 5% of adults2. Across population, Prevalence rates vary from 2.2% to 16.1% in clinical versus community cohorts. Its frequency has been reported as high as 34% ADHD in clinical setting in Pakistan3. There was a myth for many years that the disorder remits during adolescence, but it is now well established that it can be experienced by a patient in adulthood as well. There is a bidirectional overlap between ADHD and drug abuse and dependence4 and affect 27% of adult population5. The co-occurrence of ADHD and addiction is very common. Previous studies have shown that adults with ADHD are a risk for substance use disorder (SUD) and almost 52% of adult had a lifetime history of SUD2, 3. The co-morbidity between ADHD and SU shows relativity and relevant to research and clinical development in psychiatry, pediatrics and psychology5. The diagnosing and specific risk factor associated with SU within ADHD may lead to a better targeted pharmacotherapy and psychotherapeutic treatments for both the disorders upon expression at early stage of their lives7, 8. Higher rates of ADHD have been reported in patients having SUD relative to controls9, 10. 15% to 25% adults with SUD history have been estimated to have ADHD9. Studies have conducted in juvenile adolescents for assessing ADHD and other disorders in substance abusing groups had overrepresentation of ADHD10, 11. ADHD predominates from 15% to 25% in individuals with SUD12, 13. Two studies showed that the 24% of 201 inpatients14 and 10% cocaine abusers for drug detoxification treatment had ADHD15. The treatment of ADHD is usually done with stimulants like methylphenidate, amphetamine etc., with the behavioral therapy of the patient and family counseling.
SparksDuncan2013: Outside the Black Box: Re-assessing Pediatric Antidepressan...Barry Duncan
Sparks, J., & Duncan, B. (2013). Outside the black box: Re-assessing pediatric antidepressant prescription. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 22, 240-256.
Objective: The purpose of this review is to assess whether evidence supports a favorable risk/benefit profile for pediatric antidepressant use and reconsideration of the black box. Method: The review examines studies post-black box purporting to show declines in pediatric antidepressant use and rising youth suicide, summarizes evidence for efficacy and safety of pediatric antidepressants, and discusses irregularities in recent meta-analyses of fluoxetine for youth. Results: Pediatric antidepressant prescription did not significantly decline post-black box and youth suicide has risen only in recent years. Recent meta-analyses fail to undermine evidence that antidepressants are associated with increased risk of suicidality in youth. Conclusions: First line prescription of antidepressants for youth is not advisable. The black box and international warnings on pediatric use of antidepressants are warranted. Wider availability of psychosocial options for depressed youth is recommended.
KEYNOTE presentation (June 2015), ESCAP Expert Paper (July 2015), TV interview and abstract by professor Beate Herpertz-Dahlmann (Aachen University) on new developments in the diagnostics and treatment of adolescent eating disorders
Balihoo's software solutions increase the ROI of digital advertising for national brands and their agencies. By dramatically improving the relevance of paid search and display ads over other campaign management solutions, Balihoo has proven their ability to increase click-through-rates and decrease average cost-per-click while simultaneously saving you manual tasks and setup time. The result is the most efficient and effective way to deploy your digital campaigns.
Seminar1240 www.thelancet.com Vol 387 March 19, 2016.docxtcarolyn
Seminar
1240 www.thelancet.com Vol 387 March 19, 2016
Attention defi cit hyperactivity disorder
Anita Thapar, Miriam Cooper
Attention defi cit hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder with a prevalence
of 1·4–3·0%. It is more common in boys than girls. Comorbidity with childhood-onset neurodevelopmental
disorders and psychiatric disorders is substantial. ADHD is highly heritable and multifactorial; multiple genes and
non-inherited factors contribute to the disorder. Prenatal and perinatal factors have been implicated as risks, but
defi nite causes remain unknown. Most guidelines recommend a stepwise approach to treatment, beginning with
non-drug interventions and then moving to pharmacological treatment in those most severely aff ected. Randomised
controlled trials show short-term benefi ts of stimulant medication and atomoxetine. Meta-analyses of blinded trials
of non-drug treatments have not yet proven the effi cacy of such interventions. Longitudinal studies of ADHD show
heightened risk of multiple mental health and social diffi culties as well as premature mortality in adult life.
Introduction
Attention defi cit hyperactivity disorder (ADHD) is a
childhood-onset neurodevelopmental disorder char ac-
terised by developmentally inappropriate and impairing
inattention, motor hyperactivity, and impulsivity, with
diffi culties often continuing into adulthood. In this
Seminar, we aim to update and inform early career
clinicians on issues relevant to clinical practice and
discuss some controversies and misunderstandings.
Defi nitions of ADHD
ADHD is a diagnostic category in the American
Psychiatric Association’s Diagnostic and Statistical
Manual of Mental Disorders 4th edition (DSM-IV)1 and
the more recent DSM-5.2 The broadly equivalent
diagnosis used predominantly in Europe is hyperkinetic
disorder, which is defi ned in WHO’s International
Classifi cation of Diseases (10th edition; ICD-10).3 This
defi nition captures a more severely aff ected group of
individuals, since reported prevalence of hyperkinetic
disorder is lower than that of DSM-IV ADHD, even
within the same population.4 Key diagnostic criteria are
listed in the panel. DSM-5 has longer symptom
descriptors than those used in DSM-IV; these descriptors
also capture how symptoms can manifest in older
adolescents and adults. DSM-IV distinguished between
inattentive, hyperactive–impulsive, and combined sub-
types of ADHD; a diagnosis of the combined subtype
required the presence of symptoms across the domains
of inattention and hyperactivity–impulsivity. However,
ADHD subtypes are not stable across time,5 and DSM-5
has de-emphasised their distinctions. ICD-10 does not
distinguish subtypes; symptoms need to be present from
the three separate domains of inattention, hyperactivity,
and impulsivity for a diagnosis of hyperkinetic disorder.
The diagnosis of ADHD or hyperkinetic disorder also
requires the pre.
Running head UNTREATED ADHD CAN INCREASE CRIMINAL BEHAVIOR 1.docxtodd521
Running head: UNTREATED ADHD CAN INCREASE CRIMINAL BEHAVIOR 1
UNTREATED ADHD CAN INCREASE CRIMINAL BEHAVIOR 9
Untreated ADHD can increase Criminal Behavior
Jailya Wooden
Walden University
April 4, 2020
Introduction
The treatment of ADHD and the approaches to be employed are reliant on several factors including the age of the individuals suffering the disease, whether to be employed with other approaches and the comorbidities present. ADHD is a major issue in public health and can have negative effects on the families of the patient and society as a whole. As such, understanding the underlying factors of ADHD, its diagnosis and treatment approaches is crucial to how well the condition will be dealt with in the future. This paper looks into six research articles as part of the Capstone project and their studies of ADHD related subjects.
Articles Synthesis
According to Lücke et al., 2017, CBT or cognitive behavioral therapy is characterized as the standard type of psychotherapy administered in adults suffering ADHD. The article recognizes that biological factors including chronic negative feedback during childhood can play a role in the characterization of ADHD as a developmental disorder and these cannot be addressed substantially using CBT. The article looks into schema therapy which has recently become popular for use as a therapy approach when it comes to chronic psychiatric disorders due to its effectiveness. The therapy is centered on the targeting and identification of beliefs and dysfunctional patterns that are formed from experiences during childhood and encapsulated as early maladaptive schemas. The article also looks into studies that were used to demonstrate the increased prevalence of these schemas in ADHD suffering adults. As such, it analyzes the effectiveness and utilization of schema therapy and its potential in utilizing maladaptive schemas to treat ADHD. The effectiveness of the approach is bolstered when there are the influence and existence of secondary problems including impaired self-perception and poor coping mechanisms (Lücke et al., 2017). The article also cites the importance of conducting controlled randomized clinical studies to support the adoption of the approach and the analysis of its effectiveness in treating attention-deficit hyperactivity disorder, ADHD.
According to Pan et al., 2019, the article looks into a study that compares CBT alone to its combination with medication in terms of cognitive and social functions, self-esteem, emotional symptoms and core symptoms in patients suffering ADHD. The study provides proof that CBT is an effective approach when it comes to treating ADHD regardless of whether it is employed with medication or not. There were, however, broader improvements when CBT was employed with medication in executive function but not in clinical symptoms, as compared to the use of CBT alone. This would, therefore, provide a scientific basis for the clinical selection of tr.
Reply to Comment· Collapse SubdiscussionEmilia EgwimEmil.docxlillie234567
Reply to Comment
·
Collapse SubdiscussionEmilia Egwim
Emilia Egwim
8:33amDec 21 at 8:33am
Manage Discussion Entry
Discussion for Comprehensive Focused Soap Psychiatric Evaluation
Hello Lovelyne
Great presentation; I really enjoy reading your presentation about your patient Joey which is very informative. Autism Spectrum disorder is a neurodevelopmental disorder that is associated with tenacious predicaments in social communication and interaction in addition with limited, continual model of behaviors. According to study by Fitzpatrick et al; indicated that aggression behavior are noted to be increased in individual with ASD than when compared with other neurodevelopmental impairments (2016). This aggressive behavioral issues has been indicated by studies to relate with obstructive consequences for children diagnosed with ASD and their care providers resulting in reduced quality of life, heightened stress levels and decreased accessibility of educational and social adaptation/acceptance. Studies indicated that establishing effective therapeutic and pharmacological intervention approach for treatment as well as preventing aggressive behavior is imperative for reaching to better outcomes for individual with ASD. The patient in this case presentation had history of ASD and endorses aggression and self-injuries behaviors which have been indicated by various studies to associated with ASD and other manifestation including hyperactive, impulsive, inattentive behavior, unusual mood or emotional reaction.
To answer your question “
Is Risperidone FDA approved for patients with Autism”
Based on various studies, Risperidone and aripiprazole are approved by FDA and recommended for treatment of schizophrenia and bipolar for adult and adolescent including children with Autism Spectrum disorder around age 5 to 16 years. The Risperidone an antipsychotic medication was recommended to treat the aggression, irritability and mood swings associated with ASD. According to study; Risperidone has been effecting in treating symptoms of aggression and irritability between the age of 5 and 6 years distinctly that is associated with ASD, however, there’s no FDA approved medication for treatment of core sign and symptoms of ASD (Alayouf et al, 2021). There have been several controversy surrounding the use of Risperidone in which several clinician trials conducted reported that the medication was effective for the agitation, aggression and irritability often observed in autism patient, but was less effective in treating the core symptoms of Autism and other argument including the undesirable side effects that are associated with the medication and most significant of which is weight gain from an increased appetite. Other several medication as well as off-label prescription has been indicated to be effective such as treatment with SSRIs, CNS stimulants, NMDA-receptor antagonists, and including other agents (LeClerc & Easley, 2015). I completely agree with th.
ADHD and Addiction: Diagnosis and ManagementJacob Kagan
Presentation by Jacob Kagan MD on the diagnosis and management of ADHD and Substance Abuse Disorders, including epidemiology and comorbid conditions,
causality and functional impact, potential explanations for the ADHD/SUD association,stimulant treatment and the risk for SUDs, diversion and misuse of stimulant medications, and treatment recommendations. http://jacobkaganmd.com
1Proposal Effectiveness of non-pharmacological in Compari.docxdurantheseldine
1
Proposal: Effectiveness of non-pharmacological in Comparison to
Methylphenidate Stimulant Therapy
Barbara Maclure
9/18/2022
2
Effectiveness of non-pharmacological in Comparison to
Methylphenidate Stimulant Therapy
Introduction
Attentive–deficit hyperactivity is a psychological disorder that is well known, affecting
both children and adults. Some of the associated symptoms that are associated with ADHD include
inattention, hyperactivity, impulsivity, and difficulty in focusing. It is reported that in the United
States, about 8.5% of children are affected by ADHD. In the treatment process, several ways have
been put into place. Despite the treatment, many studies reported that some treatment methods
have side effects. Therefore, knowing the method that least has the side effects is crucial. This
research proposal will play an essential role as it will identify whether non-pharmacological
intervention, behavioral therapy, and stimulant therapy have the same results in children aged 4 to
8.
Background of the study
Dr. George first identified ADHD when he was a pediatrician. He noted that his patients
had uncontrollable impulsive behavior. There was an introduction of the drug Benzedrine, which
was approved as it showed to improve ADHD symptoms in children. In 1950 there was the
introduction of Ritalin drugs which were used in ADHD treatment in both children and
adolescents. (Holland & Higuera (2017). The drug that is used in the treatment of ADHD to date is
Ritalin. Despite the doctors treating patients with ADHD symptoms from the 1930s, there was no
actual definition of ADHD. Still, it was given much attention in 1987 when the American
Psychiatric Association (APA) redefinition of the disorder.
3
By 2020, approximately 7.1 million young children aging between 2-17 years with ADHD
had been diagnosed. (Garbe (2018). Despite the prevalence of the disorder among children and
adolescents, ADHD is also present in adulthood. In most cases, this disorder is noted when the
child gets into the class and starts issues of failing to focus on the classroom. There are different
forms of ADHD which entails hyperactive/impulsive type, inattentive type, or a combination of the
two. There is a criterion that is customarily utilized in the treatment of ADHD. The parents and the
teacher are required to document the children's symptoms for a period of six months. Research
shows that ADHD is more common in males than women. One of the interventions utilized is
stimulant therapy, considered standard treatment for children after reaching an appropriate age.
The stimulus, for example, the medication, is said to have side effects which can be either mild or
severe. Some noticeable side effects include upset stomach, appetite change, heart abnormalities,
tics, and weight loss. Although the treated symbols are 70-80% treated, there can be the utilization
of.
Returning genetic research results in neurodevelopmental disorders: report an...KBHN KT
This report originated from discussions at the Annual Brain Development Conference in
late 2013 between researchers in the Neuroethics Core and Autism Spectrum Disorders
Project of NeuroDevNet. Discussants felt that return of research results is a pertinent
issue but that researchers are missing a comprehensive picture of the recommendations,
approaches and empirical data related to the return of research results in genetics studies
in children, in neurodevelopmental disorders, and specifically in autism.
This report provides an overview of recent genetic studies of autism spectrum disorder
(ASD), and reviews the ethical guidance (policies and peer-reviewed literature) and
best practices on the return of individual research results in adult and pediatric genetic
research. We focus on this case because of the wealth of genetic research being
carried out in families and cohorts to explain the etiology of ASD and because there is a
burgeoning literature on parental perspectives on the return of results in this case. The
empirical perspectives are collected and summarized and provide context with regard to
researcher and parent perspectives on the return of genetic results in ASD studies.
We conclude by making recommendations about the return of both incidental and
ASD-related findings and highlight issues that merit further discussion, including the
role of the child or adolescent with developmental disability in decision-making, and
the importance of risk communication. We believe that the report will be of use not only
for those working in the area of ASD but more broadly in the field of pediatric genetic
research and neurodevelopmental disorder research. For example, the publication of new
evidence showing that genetic alterations play an important role in the etiology of cerebral
palsy in some children means that genetic research may becoming increasingly common
in other areas of the study of neurodevelopmental disorders.
11. Identifying the Elements of the Limitations & ImplicationsGo tBenitoSumpter862
11. Identifying the Elements of the Limitations & Implications
Go to the Limitations/Implications section(s) and identify the limitations of the study and how those limitations impacted the whole study.
12. Identifying the Elements of the Conclusion Section
Go to the Conclusion section and identify the conclusive statements of the study and the recommendations made for future research.
POST # 1 EDITHA
When assessing an adolescent with bipolar disorder, what are some of the diagnostic and treatment challenges the clinician might face?
Bipolar disorder is a serious mental health disorder that is often first diagnosed during young adulthood or adolescence. Symptoms of the illness, however, also can appear in early childhood. Although once thought rare in children, diagnosis of bipolar disorder in children has significantly increased over the last decade (Papolos & Bronsteen, 2018). Despite the increased diagnosis of bipolar disorder in children, assessment and diagnosis remain challenging and controversial. This is, in part, because of the lack of research on this disorder in children and adolescents and the growing recognition that the disease can present differently in children from how it presents in adults (AACAP, 2019). Over the years, more attention has focused on the unique presentation of bipolar disorder in the young that has introduced new ways of looking at this disease and assessing it in children.
The importance of identifying the presence of bipolar disease at an early age is highlighted by data showing that adults in whom bipolar disease started at an early age have a more severe course of the illness compared with adult-onset disease. Early-onset disease is associated with a higher risk of suicide; severe mood lability and polarity; lower quality of life and greater functional impairment; higher rates of comorbidity; and a higher risk of substance use disorders compared with adult-onset disease (Papolos & Bronsteen, 2018). Although some children meet the criteria established for adults categorized in the DSM-5, many children fall outside these classical categories, and diagnosis in these children is particularly challenging and difficult (APA, 2013). For these children, additional information beyond what is provided in the DSM may help make an accurate diagnosis which causes increased challenges in assessment and diagnosis.
References
Papolos, D, & Bronsteen A. (2018) bipolar disorder in children: assessment in general pediatric practice. Curr Opin Pediatr, 25(3):419-426.
American Academy of Child and Adolescent Psychiatry (AACAP). (2019) bipolar disorder: Parents’ Medication Guide for Bipolar Disorder in Children & Adolescents.
American Psychiatric Association (APA) (2013). Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Washington, DC: American Psychiatric Association.
RESEARCH ARTICLE
Association of suicidal behavior with exposure
to suicide and suicide attempt: A systematic
...
11. Identifying the Elements of the Limitations & ImplicationsGo tSantosConleyha
11. Identifying the Elements of the Limitations & Implications
Go to the Limitations/Implications section(s) and identify the limitations of the study and how those limitations impacted the whole study.
12. Identifying the Elements of the Conclusion Section
Go to the Conclusion section and identify the conclusive statements of the study and the recommendations made for future research.
POST # 1 EDITHA
When assessing an adolescent with bipolar disorder, what are some of the diagnostic and treatment challenges the clinician might face?
Bipolar disorder is a serious mental health disorder that is often first diagnosed during young adulthood or adolescence. Symptoms of the illness, however, also can appear in early childhood. Although once thought rare in children, diagnosis of bipolar disorder in children has significantly increased over the last decade (Papolos & Bronsteen, 2018). Despite the increased diagnosis of bipolar disorder in children, assessment and diagnosis remain challenging and controversial. This is, in part, because of the lack of research on this disorder in children and adolescents and the growing recognition that the disease can present differently in children from how it presents in adults (AACAP, 2019). Over the years, more attention has focused on the unique presentation of bipolar disorder in the young that has introduced new ways of looking at this disease and assessing it in children.
The importance of identifying the presence of bipolar disease at an early age is highlighted by data showing that adults in whom bipolar disease started at an early age have a more severe course of the illness compared with adult-onset disease. Early-onset disease is associated with a higher risk of suicide; severe mood lability and polarity; lower quality of life and greater functional impairment; higher rates of comorbidity; and a higher risk of substance use disorders compared with adult-onset disease (Papolos & Bronsteen, 2018). Although some children meet the criteria established for adults categorized in the DSM-5, many children fall outside these classical categories, and diagnosis in these children is particularly challenging and difficult (APA, 2013). For these children, additional information beyond what is provided in the DSM may help make an accurate diagnosis which causes increased challenges in assessment and diagnosis.
References
Papolos, D, & Bronsteen A. (2018) bipolar disorder in children: assessment in general pediatric practice. Curr Opin Pediatr, 25(3):419-426.
American Academy of Child and Adolescent Psychiatry (AACAP). (2019) bipolar disorder: Parents’ Medication Guide for Bipolar Disorder in Children & Adolescents.
American Psychiatric Association (APA) (2013). Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Washington, DC: American Psychiatric Association.
RESEARCH ARTICLE
Association of suicidal behavior with exposure
to suicide and suicide attempt: A systematic
...
Running head AWARENESS OF AUTISM 1 Awareness o.docxjoellemurphey
Running head: AWARENESS OF AUTISM 1
Awareness of Autism
Name
Tutor
Institution
Course
Date
AWARENESS OF AUTISM 2
The main objective was to assess the existing knowledge as well as perception that the
primary school teachers had regarding autism. Therefore, the study was conducted in both the
private and the public schools in Pakistan. Basically, autism is a disorder of the neural
development which is normally characterized by the impaired social interaction, communications
and through restriction of a repetitive behavior. Normally, this condition will begin at birth and
the children that are affected are normal in their appearance but they normally spend a lot of their
time engaged and even puzzled and very disturbing behaviors which are normally different from
those of the typical students. There have been several tools and studies regarding the disease and
the prevalence in the population (Muhammad & Farah, 2013). Therefore, the study was
primarily conducted with the sole aim of determining the level of autism awareness amongst the
primary school teachers and the results were intended to help the school and surrounding
organization to increase the awareness levels in terms of autism so that it could be diagnosed at
an early age and thus intervention could be done as early as possible.
For the methods used to complete the study, there was a cross sectional study that was
conducted in the primary school teachers where the sample size was also calculated. Quite a
number of teachers were selected with the use of simple random sampling. Further, there was a
questionnaire that was used, designed to make assess on the various aspects of their knowledge
like diagnosis, the symptoms as well as the treatment. In addition, frequencies as well as various
percentages were taken out of each and every category. There was also a chi-square test that was
applied for the purpose of finding out the available differences between two variables
(Muhammad & Farah, 2013).
From the study, in making comparison on the responses concerning the knowledge of
autism in all categories, it was discovered that there was indeed no statistical significance except
AWARENESS OF AUTISM 3
in the categories of communication skills of a child with autism disorder and the emotional
temperament of the same child. It was discovered that the teachers in the public sector had better
awareness that the children with autism disorder had poor communication skills and thus could
not express themselves. In the private sector, the teachers were more aware of the disorder and
highly recognized that a child with this disorder would throw frequent bouts of rage. Therefore,
it was concluded that the teachers in the public sector proved to have better knowledge as well as
perception of autism as compared to the teachers from the private sector (Muhammad & Farah,
2013).
Normally, autism disorder h ...
Due Monday August 22, 2016 8am $40.00 please be 100 original OP.docxhasselldelisa
Due Monday August 22, 2016 8am
$40.00 please be 100% original
OPPOSITIONAL DISORDER DISEASE
The research paper will be any disease or condition of the body. The paper must include a thorough description of the disease/condition; current statistics of those affected - epidemiology; financial costs both terms of treatment and loss of productivity; explanations on how the various body systems (anatomically and/or physiologically) are affected; etiology; medications/treatments that are available; prognosis of those affected, and future outlook in general.
Research paper must have 1200 words no more then 1500 not to include abstract,cover paper,annotate.
* cover/title page (page 1)
* corrected abstract (page 2) ( abstract paper turn in I am missing a lot of work )
Must be in the abstract
Statistic/ Epidemiology
Financial cost
Anatomy & Physiology
Etiology (cause)
Diagnosis/ treatment/ prognosis
Abstract
In recent a post, oppositional disorder diseases has been on the rise, raising questions about the manner in which diseases is spreading especially among children. The high prevalence levels of the oppositional disorder have raised more concerns especially form the health, sectors thus developing the need to understand the disorder better. This research paper will, therefore, encompass a broad perspective of oppositional disorder disease to effectively understand how it is manifested, various ways in which it manifests itself to develop preventive strategy much earlier before the situation reaches full-blown.
Unlike the common conduct disorder where the patient is more aggressive towards people and animals, the oppositional disorder is more silent, and it takes time for it to be detected. The lifetime prevalence of the disease is estimated to be 10.2%. The disease is mostly observed in children and adolescents across the globe.
Some of the common symptoms of the disease involve a certain behavior where children’s behavior is much different compared to their peers. A patient suffering from oppositional disorder tends to have a turn in their behavior including regular loose of temper, being angry and resentful, argues with authorities without any significant reason. It is importance to note that the persistence and frequency of these behaviors should be used to differentiate between normal behavior and symptoms of the oppositional disorder. The disease causes a massive effect on patient’s mental and physical wellbeing.
The most common cause of the oppositional disorder is the genetic influence. Research has shown that parents tend to pass on expressing disorder to their children, and it may be displayed in multiple ways. The disease can be easily diagnosed basing on the extent at which the change of behavior causes distress to the family members or drastic changes in academic and social functioning. These behaviors must persist.
Similar to ANTH336_The Proximate Causes of ADHD (20)
2. Pittsley 2
According to the DSM-5, ADHD is characterized by “a persistent pattern of inattention
and/or hyperactivity-impulsivity that interferes with functioning or development”. Common
inattentive symptoms include “wandering off task, lacking persistence, having difficulty
sustaining focus, and being disorganized…”, while common hyperactivity-impulsivity symptoms
include “excessive motor activity, fidgeting, tapping, or talkativeness when not appropriate” and
“hasty actions that occur in the moment without forethought and have a high potential for
harm…”. Diagnosis occurs if a certain number of characteristic symptoms are present by the age
of 12, are variably present in two or more settings, and “there is clear evidence that the
symptoms interfere with… social, academic, or occupational functioning” (APA 2013:97-99).
While prevalence rates vary greatly across many dimensions, as of 2011, about 11% of children
in the United States had been diagnosed with ADHD, and just over 6% had been prescribed
medication for ADHD treatment (Visser et al. 2014). Similarly, ADHD prevalence rates for
adults have been found to be around 5%. This makes ADHD one of the most commonly
diagnosed psychological disorders, and its prevalence rates are increasing (Franke et al. 2012).
Accordingly, much research into the etiology of ADHD has been conducted over the past few
decades, including heritability studies, molecular genetic analyses, maternal exposure studies,
and environmental exposure assessments. In this paper I will provide an overview of this
research and review the most up-to-date findings, beginning with genetics-related studies, and
then addressing studies related to maternal, prenatal, and perinatal factors, and finally discussing
environmental exposure studies. I will then conclude by summarizing my important points and
discussing the limitations of etiological inquiry into ADHD.
3. Pittsley 3
GENETIC RESEARCH
Much of the early research into ADHD and its causes focused on the heritability of the
condition and its symptoms and consisted of numerous twin and adoption studies. Results of this
research were promising; heritability estimates tended to be high, hovering between 60% and
90% between various studies. Adoption studies showed a significant correlation between ADHD
diagnosis in adopted children and their biological parents, but no such correlation in diagnosis
between them and their adoptive parents (Sprich et al. 2000). Many twin studies, while not
measuring ADHD diagnosis directly as a variable, measured “attention problems” (Rietveld et al.
2003) and “hyperactivity” (Thapar et al. 1995), which are synonymous with ADHD symptoms.
These studies found such symptoms to have heritability scores of 68% to 76% in the case of
attention problems, and 88% in the case of hyperactivity. With the importance of genetic
contributions to ADHD seeming clear, later genetics research focused on the molecular genetics
of ADHD; consisting mostly of genome-wide association studies (GWAS) and candidate gene
analyses. The results of the GWAS studies were not promising. In the largest GWAS conducted
on ADHD to this date, a meta-analysis of four other such studies, still no significant genome-
wide associations were found (Neale et al. 2010). Two different conclusions have arisen out of
these results. On one hand, the sample size of even this large GWAS was smaller than most other
successful association studies, and ADHD diagnoses may vary between studies, introducing
more variability into the sample size. Increasing sample size and correcting for diagnostic
variability may produce more positive results in the future. On the other hand, the negative
results may indicate that the genetic component of ADHD is highly complex, perhaps involving
a wide variety of different genes with small effects. To test this explanation, candidate gene
studies have targeted genes thought to be related to the physiopathology of ADHD, and their
4. Pittsley 4
results seem to support the idea of a wide variety of small-effect genes. Candidate genes
involved with the neurotransmitters dopamine and serotonin have been to most studied, and
shown the most positive results. Pooled odds ratios from 1.13 to 1.45 were observed for five
different genes related to the dopaminergic system. Similarly, two genes related to the
serotonergic system had observed odds ratios of 1.31 and 1.44 (Faraone et al. 2005). Despite the
positive results of candidate gene studies, no causal genetic or physiological mechanisms have
been found for ADHD. Rather, research has so far come to the conclusion that genes are only a
part, albeit an important part, of a larger etiology involving environmental exposures and gene-
environment interactions.
MATERNAL, PRENATAL, & PERINATAL FACTORS RESEARCH
A relatively large amount of research has focused on maternal behaviors during
pregnancy, as well as prenatal and perinatal conditions, and their effect on ADHD risk. Maternal
stress and smoking are two of the most commonly studied risk factors, and research has so far
shown positive results. An analysis combining numerous maternal smoking studies found an
odds ratio of 2.39 with a confidence interval of 1.61 to 3.52 for the risk of maternal smoking on
ADHD diagnosis (Langley et al. 2005). One study on the effects of maternal stress found that
moderate and severe stress during pregnancy increased the chance of a child being diagnosed
with ADHD (Grizenko et al. 2008), and another study of the same risk factor found an odds ratio
between 1.65-52.38, but only for boys (Rodriguez and Bohlin 2005). Low birth-weight and being
born pre-term are two other risk factors for ADHD that have been commonly studied with
promising results. A meta-analysis combining seven studies relating pre-term birth to ADHD
risk found a pooled relative risk of 2.64 (Bhutta et al. 2002). However, only three of the seven
studies included in the meta-analysis had a lower confidence interval of 1.00 or greater.
5. Pittsley 5
ENVIRONMENTAL EXPOSURE RESEARCH
Much environmental exposure research has also been conducted to find any potential
relationship between ADHD and environmental toxins and pollution. While many substances
have been studied in this manner, the ones I present here are the most commonly studied and
have shown the most promising results. Exposure to lead, PCBS, and certain pesticides, as well
as dietary choices, have all been shown to have some relationship to ADHD and ADHD
symptoms. Bouchard et al. (2010) found that higher urinary concentrations of organophosphate
pesticide metabolites in children were correlated with an increased likelihood of being diagnosed
with ADHD. Blood concentrations of lead in children have also been found to be associated with
ADHD diagnosis, though only children with hyperactive-impulsivity-type ADHD, not those with
inattentive-type ADHD (Nigg et al. 2010). Similarly, PCB (another common toxin that, like lead,
is found in much consumer electronics and appliances) exposure in early childhood has been
associated with ADHD-like symptoms (Sagiv et al. 2010). Finally, studies of dietary effects on
ADHD have recently been conducted, prompted by policies enacted in Europe to restrict certain
food addivites. Nigg et al. (2012) compiled numerous dietary studies and found that restriction
diets reduced ADHD symptoms in children, and that eliminating food colors in the diet had some
effect on children’s ADHD symptoms.
LIMITATIONS & CONCLUSION
Despite the successful findings of the large amount of ADHD-research, to this date the
largest limitation remains ADHD’s nebulous quality. ADHD’s diagnostic criteria cover a diffuse
cluster of symptoms ranging from over-activity (hyperactivity, impulsivity, etc.) to under-
activity (inattention, inability to complete tasks, etc.). Comorbidity with many other conditions
6. Pittsley 6
like anxiety is also extremely common in those with ADHD (Shea et al. 2014), and symptoms of
comorbid conditions and ADHD frequently overlap. Thus, I would posit, it seems that ADHD
functions more as a diagnostic label for a cluster of symptoms that may or may not originate
from numerous somewhat similar conditions with equally numerous etiologies. The research
presented in this paper support this claim. There is good reason to believe that genetic and
environmental factors influence attention and hyperactivity-impulsivity, but that these factors are
myriad, sometimes interdependent, rarely independent, and lead to similar, but still diverse
psychological and behavioral outcomes. These psycho-behavioral outcomes, when they manifest
appropriately, are defined as ADHD.
It is here where we see socio-cultural factors becoming relevant and playing a role in the
proximate causes of ADHD. Diagnosis, as Jutel (2009:279) argues, “enables the social
incorporation of the afflicted individual, with the allowance for, or tools to palliate and explain”.
The processes of creating and using a diagnosis are not methods of discovery, either discovery of
a disease itself or its presence in a particular individual. Rather, diagnosis is a classification tool,
a cultural schema, which allows the medical community to carry out its role. Every culture has
ways of dealing with deviance and abnormality; sometimes schizophrenics become shamans,
sometime they become marginalized, and other times they are treated with medicine. The case of
ADHD is no different. One could argue that the proximate cause of ADHD is the culture that
demands behavioral and productive conformity to social institutions, namely school and work in
this particular case. The inattentive (unproductive) and hyperactive (abnormal) individual is
identified through diagnosis and allowed to enter the proper channels that mitigate the effects of
such deviance through medication, therapy, and other treatments. The importance of
sociocultural causes may serve as a powerful explanation for ADHD’s varying prevalence
7. Pittsley 7
among different geographies, cultural groups, and genders, as well as numerous other variables
(Skounti et al. 2007).
However, ADHD cannot be so readily dismissed as a “cultural irreality” (ignoring
for now, the contradictions in such a term). People have ADHD, or perhaps more accurately,
people vary psychologically in their executive functioning, or their ability to sustain attention
and control impulsivity. Variety is nothing new, and some amount can be accommodated without
much effort in many cases. But when such variety crosses some threshold, is interpreted as being
too different, diagnosis occurs, and the variety is called “ADHD”. This is also not necessarily a
bad thing for those labeled with such diagnoses. Many instances of a disease being “created”
through such medicalization have led sufferers to receive help that has drastically improved their
lives, as is the case with PTSD (Conrad 1992). It is clear that ADHD-like symptoms are
detrimental to those subject to the demands of modern educational and occupational institutions,
and that inability to function in these institutions leads to suffering. The relevance of genetic,
environmental, developmental, and sociocultural factors to the etiology of ADHD-like symptoms
is demonstrated by the research. Variation in attention, hyperactivity, and impulsivity exist, and a
certain band of this variation has come to be defined as ADHD.
8. Pittsley 8
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