Medium frequency currents between 1000-10000 Hz are used therapeutically for pain management and wound healing. Rebox, Russian, and interferential currents are types of medium frequency currents. Interferential currents use two medium frequencies (e.g. 4000 Hz and 3900 Hz) that interfere in tissues to produce a low frequency beat current for deep tissue treatment without skin irritation. Common applications include pain, muscle spasm, edema, and delayed bone healing.