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CYSTS OF OROFACIAL
REGION
Dr. Haydar Munir Salih Alnamer
Maxillofacial specialist
BDS, Ph.D (Board certified)
• Cysts are the most common cause of chronic swellings of the jaws.
They are more common in the jaws than in any other bone
because of the many rests of odontogenic epithelium remaining in
the tissues
• Cyst is define as pathologic cavity within the hard or soft
tissues, lined by epithelium and contain fluid, semifluid or
gas (not created by accumulation of pus) and surrounded
by connective tissue wall or capsule.
THE MAIN MECHANISMS OF CYST FORMATION
INVOLVED IN VARYING DEGREES:
1.Proliferation of the epithelial lining and
connective tissue capsule
2. Accumulation of fluid within the cyst
3. the resorption of the surrounding bone
CLINICAL FEATURES OF JAW CYST
• Most jaw cysts behave similarly and usually grow slowly
and expansively.
• They differ mainly in their relationship to a tooth, and
the radiographic features are usually a good guide as to
their nature.
• Even when it is not possible to decide the nature of a
cyst, this affects treatment only with less common types.
(keratocysts and unicystic ameloblastomas)
• Diagnosis ultimately depends on histopathology
KEY FEATURES OF JAW CYSTS
•Form sharply-defined radiolucencies with smooth
borders
•Fluid may be aspirated and thin-walled cysts may
be transilluminated
•Grow slowly, displacing rather than resorbing
teeth
•Symptomless unless infected and are frequently
chance radiographic findings
KEY FEATURES OF JAW CYSTS
•Rarely large enough to cause pathological fracture
•Form compressible and fluctuant swellings if
extending into soft tissues
•Appear bluish when close to the mucosal surface
•Large cysts usually deflect the neurovascular
bundle, paresthesia and anesthesia is rare
CLASSIFICATION OF CYST
1. intra- osseous cyst
2. Soft tissue cyst
INTRAOSSEOUS CYST
I. Epithelial Cysts:
Odontogenic epithelial origin
Developmental
Primordial cyst (keratocyst)
Dentigerous (follicular) cyst
Calcifying odontogenic (Gorlin) cyst
Eruption cyst
Lateral periodontal cyst
Inflammatory
Radicular cyst (apical/lateral periodontal)
Residual cyst
INTRAOSSEOUS CYST
I. Epithelial Cysts:
Non-odontogenic epithelial origin (Fissural cyst):
Median mandibular
Median palatal
Globulomaxillary
Incisive canal (nasopalatine duct or median anterior
maxillary) cyst
INTRAOSSEOUS CYST
II. Non-epithelial cysts: (PSUDOCYST)
Solitary bone cyst (traumatic)
Aneurysmal bone cyst
Stafne’s bone cavity
III. Cyst of the maxillary antrum:
Surgical ciliated cyst of maxilla
Benign mucosal cyst of the maxillary antrum
SOFT TISSUE CYST
Odontogenic Gingival cysts:
Adult
Newborn
Non-odontogenic (fissural)
Anterior median lingual cyst
Nasolabial cyst
Retention cysts: Salivary gland cysts
Mucocele
Ranula
SOFT TISSUE CYST
Developmental/congenital cysts:
Dermoid and epidermoid cysts
Branchial cyst (cervical/intraoral)
Thyroglossal duct cyst
Cystic hygroma
INFLAMMATORY RADICULAR CYST
• The most common of all cysts of odontogenic origin.
(65%- 70%)
• The involved tooth is non-vital.
• The incidence is highest in the anterior maxillary and the
posterior mandibular teeth.
• A round or ovoid shaped radiolucency
• A straw colored or brownish fluid and cholesterol
crystals.
• Treatment: enucleation
LATERAL RADICULAR CYST
RESIDUAL RADICULAR CYST
RADICULAR CYST ASPIRATION
KERATOCYST
• It is about 5 to 10% of odontogenic cysts of the jaws
• tend to grow in an anteroposterior direction within the
medullary cavity and clinically observable expansion of
the bone occurs late
• The teeth adjoining the cyst are vital
• can be unilocular or multilocular
• contain cheesy like material
MULTILOCULAR KERATOCYST
UNILOCULAR KERATOCYST
CONTENT OF KERATOCYST
RECURRENCE OF KERATOCYST
•The recurrence rate may vary from 5-60% with
most occurring in the first 5 years.
•Some of the possible reasons reported for
recurrence are as follows:
1. Presence of satellite cysts,
2. Cystic lining is very thin and fragile,
3. portions of which may be left behind
ENUCLEATION
PERIPHERAL OSTECTOMY
CARNOYS' SOLUTION
EN-BLOCK RESECTION
GORLIN-GOLTZ SYNDROME
DENTIGEROUS CYST
• Results because of the enlargement of the follicular
space of the whole or part of the crown of an impacted
or unerupted tooth and is attached to the neck of the
tooth.
• More common than the keratocyst but less common
than the inflammatory types
• dentigerous cysts have a higher tendency to cause root
resorption of adjacent teeth
• Treatment: marsupialization in children and enucleation
in adult
DENTIGEROUS CYST
DENTIGEROUS CYST
Gingival cyst of infants
• (Bohn nodules) up to 80% of newborn infants have small
nodules or cysts in the gingivae Most resolve spontaneously
• Cysts (Epstein's pearls) may also arise from nonodontogenic
epithelium along the midpalatine raphe. also resolve
spontaneously in a matter of months.
Gingival cysts of adults
• Gingival cysts are exceedingly rare. They usually form after
the age of approximately 40. Clinically, they form dome-
shaped swellings less than 1 cm in diameter and sometimes
erode the underlying bone. They are unlikely to recur after
enucleation
BOHEN NODULES Epstein pearls
GINGIVAL CYST OF THE ADULT
FISSURAL CYSTS
•Fissural cysts are non-odontogenic cysts that
arise owning to epithelial inclusions or
entrapments in the lines of fusion of the
developing facial processes during the
embryonic stage.
FISSURAL CYSTS
MEDIAN PALATINE CYST
NASOPALATINE CYST
NASOPALATINE CYST
GLOBULOMAXILLARY CYST
GLOBULOMAXILLARY CYST
SOLITARY BONE CYST
& ANEURYSMAL BONE CYST
•Solitary bone cyst and aneurysmal bone cysts are
without epithelial lining (pseudocysts). These also
are cystic only in their radiographic appearances
•It is not confined to the jaws as similar lesions are
seen elsewhere in the skeleton
•Mainly due to trauma
•It is seen mainly in children, adolescents or young
adults
SOLITARY BONE CYST
ANEURYSMAL BONE CYST
STAFNE BONE CAVITY
•Stafne's bone cavity is not a cyst, it is included
because of their clinical similarity to cysts of the
jaw bones
•due to failure of the normal deposition of bone
during development of the jaws
•Below the inferior alveolar canal, mainly unilateral
•No treatment
STAFNE BONE CAVITY
MUCOCELE & RANULA
• Two types of distinct entities described are, the true
retention cyst which is lined by epithelium and the other
is the mucous extravasation cyst which occurs because
of the pooling of mucus, it does not have any epithelial
lining and is surrounded by connective tissue cells
• Majority of mucocele are seen to affect the lower lip
• Ranula is variant of a mucocele that is present on the
floor of the mouth, beneath the tongue.
• Treatment: They are best treated by surgical excision
together with the associated salivary gland
RANULA
PLUNGING RANULA
DERMOID AND EPIDERMOID CYSTS
• The dermoid cyst is a form of cystic teratoma, which is lined
by epithelium and in addition reveals the presence of skin
appendages, e.g. hair, sebaceous glands or teeth. The
epidermoid cyst is also lined by epithelium but does not
contain any skin appendages.
• Dermoid are seen in the midline in the floor of the mouth
above or below the geniohyoid muscle
• Those above the geniohyoid muscle, elevate the tongue,
causing difficulty with mastication and speech. Those
present inferior to the geniohyoid muscle, cause a
submental swelling that has been described as a double
chin
DERMOID AND EPIDERMOID CYSTS
DERMOID AND EPIDERMOID CYSTS
DERMOID AND EPIDERMOID CYSTS
THYROGLOSSAL DUCT CYST
• It can occur anywhere in the midline along the course of
the embryonic thyroglossal duct,
(which extends from the foramen caecum of the tongue
into the deep fascia near the thyroid isthmus)
• Pathognomonic is the movement of the cyst during
swallowing and protrusion of the tongue
• Complete radical surgical excision of the cyst along with
its tract is essential to prevent recurrence.
THYROGLOSSAL DUCT CYST
THYROGLOSSAL DUCT CYST
THYROGLOSSAL DUCT CYST
SISTRUNK PROCEDURE
CYSTIC HYGROMA
• it is a developmental abnormality, in which cavernous lymphatic
spaces communicate and form large thin walled cysts
• Typically they appear in the first few months of life
• swelling that is painless and compressible, the swelling may
increase in size over several months to a year, and they may
remain static or may even regress
• overlying skin may be bluish and transillumination will be
positive
• Hygroma may suddenly enlarge when there is an upper
respiratory infection. This may cause acute respiratory
obstruction and may require an emergency tracheostomy or
surgical extirpation
CYSTIC HYGROMA
CYSTIC HYGROMA
Cysts of the jaws, may be treated by one of the following basic
methods:
1. Marsupialization (decompression)
• Partsch I
• Partsch II (combined marsupialization and encleation)
• Marsupialization by opening into nose or antrum.
2. Enucleation:
• Enucleation and packing
• Enucleation and primary closure
• Enucleation and primary closure with reconstruction/bone
grafting.
GENERAL PRINCIPLES OF TREATMENT
MARSUPIALIZATION (PARTSCH I)
MARSUPIALIZATION
MARSUPIALIZATION
MARSUPIALIZATION
(POSTOPERATIVE PACKING )
ACRYLIC PLUG
INDICATIONS FOR MARSUPIALIZATION
1. Age:
2.Proximity to vital structures:.
3.Eruption of teeth:
4.Size of cyst:
5.Vitality of teeth:
ADVANTAGES OF MARSUPIALIZATION
1. Simple procedure to perform and reduces operating
time
2. Spares vital structures and prevents oronasal and
oroantral fistulae
3. Alveolar ridge is preserved and allows eruption of
teeth
4. Helps shrinkage of cystic lining and prevents
pathological fracture
5. Allows for endosteal bone formation to take place.
DISADVANTAGES OF MARSUPIALIZATION
1. Pathologic tissue is left in situ
2.Histologic examination of the entire cystic lining is not
done
3. Prolonged healing time and prolonged followup visits
4. Periodic changing of pack, periodic irrigation of cavity
5. Inconvenience to the patient
6. Secondary surgery needed
7. Formation of slit-like pockets that may harbor foodstuffs
MODIFICATIONS OF MARSUPIALIZATION PARTSCH II
this is a two-stage technique that combines
the two standard procedures, in which, first
marsupialization is performed and at a later
stage when the cavity becomes smaller, the
procedure of enucleation is performed and
the entire tissue is examined
histopathologically
ENUCLEATION
ENUCLEATION
ENUCLEATION
ENUCLEATION
ENUCLEATION WITH PACKING
ENUCLEATION WITH
RECONSTRUCTION/ BONE GRAFT
ENUCLEATION WITH
RECONSTRUCTION/ BONE GRAFT
ENUCLEATION WITH
RECONSTRUCTION/ BONE GRAFT
ENUCLEATION
Indications:
1. Treatment of odontogenic keratocysts
2. Recurrence of cystic lesions
ENUCLEATION
Advantages:
1. Primary closure of the wound
2. Healing is rapid and postoperative care is
reduced
3. Thorough examination of the entire cystic lining
can be done.
ENUCLEATION
Disadvantages:
1. In young persons, the unerupted teeth in a
dentigerous cyst will be removed with the lesion
2. Removal of large cysts will weaken the mandible,
making it prone to jaw fracture
3. Damage to adjacent vital structures
4. Pulpal necrosis.
COMPLICATIONS OF CYSTIC LESIONS
1. Pathological fracture
2. Postoperative wound dehiscence
3. Loss of teeth vitality
4. Neuropraxia in infected cysts
5. Postoperative infection
6. Recurrence in some cysts
7. Dysplastic, neoplastic or even malignant changes
PATHOLOGICAL FRACTURE
SUGGESTED FOLLOW-UP:
• Long-term follow-up, at least up to 8 years for keratocysts
for early detection of dealing with any recurrence
• To check postoperative vitality of teeth
• Unerupted teeth that may require orthodontic assistance for
eruption
• Orthodontic assistance for alignment of displaced teeth
• Long-term follow-up of patients with Gorlin's syndrome.
“
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Lec 1 cysts of orofacial region

  • 1. CYSTS OF OROFACIAL REGION Dr. Haydar Munir Salih Alnamer Maxillofacial specialist BDS, Ph.D (Board certified)
  • 2.
  • 3. • Cysts are the most common cause of chronic swellings of the jaws. They are more common in the jaws than in any other bone because of the many rests of odontogenic epithelium remaining in the tissues • Cyst is define as pathologic cavity within the hard or soft tissues, lined by epithelium and contain fluid, semifluid or gas (not created by accumulation of pus) and surrounded by connective tissue wall or capsule.
  • 4. THE MAIN MECHANISMS OF CYST FORMATION INVOLVED IN VARYING DEGREES: 1.Proliferation of the epithelial lining and connective tissue capsule 2. Accumulation of fluid within the cyst 3. the resorption of the surrounding bone
  • 5.
  • 6. CLINICAL FEATURES OF JAW CYST • Most jaw cysts behave similarly and usually grow slowly and expansively. • They differ mainly in their relationship to a tooth, and the radiographic features are usually a good guide as to their nature. • Even when it is not possible to decide the nature of a cyst, this affects treatment only with less common types. (keratocysts and unicystic ameloblastomas) • Diagnosis ultimately depends on histopathology
  • 7. KEY FEATURES OF JAW CYSTS •Form sharply-defined radiolucencies with smooth borders •Fluid may be aspirated and thin-walled cysts may be transilluminated •Grow slowly, displacing rather than resorbing teeth •Symptomless unless infected and are frequently chance radiographic findings
  • 8.
  • 9.
  • 10. KEY FEATURES OF JAW CYSTS •Rarely large enough to cause pathological fracture •Form compressible and fluctuant swellings if extending into soft tissues •Appear bluish when close to the mucosal surface •Large cysts usually deflect the neurovascular bundle, paresthesia and anesthesia is rare
  • 11.
  • 12. CLASSIFICATION OF CYST 1. intra- osseous cyst 2. Soft tissue cyst
  • 13. INTRAOSSEOUS CYST I. Epithelial Cysts: Odontogenic epithelial origin Developmental Primordial cyst (keratocyst) Dentigerous (follicular) cyst Calcifying odontogenic (Gorlin) cyst Eruption cyst Lateral periodontal cyst Inflammatory Radicular cyst (apical/lateral periodontal) Residual cyst
  • 14.
  • 15. INTRAOSSEOUS CYST I. Epithelial Cysts: Non-odontogenic epithelial origin (Fissural cyst): Median mandibular Median palatal Globulomaxillary Incisive canal (nasopalatine duct or median anterior maxillary) cyst
  • 16. INTRAOSSEOUS CYST II. Non-epithelial cysts: (PSUDOCYST) Solitary bone cyst (traumatic) Aneurysmal bone cyst Stafne’s bone cavity III. Cyst of the maxillary antrum: Surgical ciliated cyst of maxilla Benign mucosal cyst of the maxillary antrum
  • 17. SOFT TISSUE CYST Odontogenic Gingival cysts: Adult Newborn Non-odontogenic (fissural) Anterior median lingual cyst Nasolabial cyst Retention cysts: Salivary gland cysts Mucocele Ranula
  • 18. SOFT TISSUE CYST Developmental/congenital cysts: Dermoid and epidermoid cysts Branchial cyst (cervical/intraoral) Thyroglossal duct cyst Cystic hygroma
  • 19. INFLAMMATORY RADICULAR CYST • The most common of all cysts of odontogenic origin. (65%- 70%) • The involved tooth is non-vital. • The incidence is highest in the anterior maxillary and the posterior mandibular teeth. • A round or ovoid shaped radiolucency • A straw colored or brownish fluid and cholesterol crystals. • Treatment: enucleation
  • 20.
  • 21.
  • 25. KERATOCYST • It is about 5 to 10% of odontogenic cysts of the jaws • tend to grow in an anteroposterior direction within the medullary cavity and clinically observable expansion of the bone occurs late • The teeth adjoining the cyst are vital • can be unilocular or multilocular • contain cheesy like material
  • 29. RECURRENCE OF KERATOCYST •The recurrence rate may vary from 5-60% with most occurring in the first 5 years. •Some of the possible reasons reported for recurrence are as follows: 1. Presence of satellite cysts, 2. Cystic lining is very thin and fragile, 3. portions of which may be left behind
  • 35. DENTIGEROUS CYST • Results because of the enlargement of the follicular space of the whole or part of the crown of an impacted or unerupted tooth and is attached to the neck of the tooth. • More common than the keratocyst but less common than the inflammatory types • dentigerous cysts have a higher tendency to cause root resorption of adjacent teeth • Treatment: marsupialization in children and enucleation in adult
  • 38. Gingival cyst of infants • (Bohn nodules) up to 80% of newborn infants have small nodules or cysts in the gingivae Most resolve spontaneously • Cysts (Epstein's pearls) may also arise from nonodontogenic epithelium along the midpalatine raphe. also resolve spontaneously in a matter of months. Gingival cysts of adults • Gingival cysts are exceedingly rare. They usually form after the age of approximately 40. Clinically, they form dome- shaped swellings less than 1 cm in diameter and sometimes erode the underlying bone. They are unlikely to recur after enucleation
  • 40. GINGIVAL CYST OF THE ADULT
  • 41. FISSURAL CYSTS •Fissural cysts are non-odontogenic cysts that arise owning to epithelial inclusions or entrapments in the lines of fusion of the developing facial processes during the embryonic stage.
  • 48. SOLITARY BONE CYST & ANEURYSMAL BONE CYST •Solitary bone cyst and aneurysmal bone cysts are without epithelial lining (pseudocysts). These also are cystic only in their radiographic appearances •It is not confined to the jaws as similar lesions are seen elsewhere in the skeleton •Mainly due to trauma •It is seen mainly in children, adolescents or young adults
  • 51. STAFNE BONE CAVITY •Stafne's bone cavity is not a cyst, it is included because of their clinical similarity to cysts of the jaw bones •due to failure of the normal deposition of bone during development of the jaws •Below the inferior alveolar canal, mainly unilateral •No treatment
  • 53. MUCOCELE & RANULA • Two types of distinct entities described are, the true retention cyst which is lined by epithelium and the other is the mucous extravasation cyst which occurs because of the pooling of mucus, it does not have any epithelial lining and is surrounded by connective tissue cells • Majority of mucocele are seen to affect the lower lip • Ranula is variant of a mucocele that is present on the floor of the mouth, beneath the tongue. • Treatment: They are best treated by surgical excision together with the associated salivary gland
  • 54.
  • 55.
  • 57.
  • 58.
  • 60.
  • 61. DERMOID AND EPIDERMOID CYSTS • The dermoid cyst is a form of cystic teratoma, which is lined by epithelium and in addition reveals the presence of skin appendages, e.g. hair, sebaceous glands or teeth. The epidermoid cyst is also lined by epithelium but does not contain any skin appendages. • Dermoid are seen in the midline in the floor of the mouth above or below the geniohyoid muscle • Those above the geniohyoid muscle, elevate the tongue, causing difficulty with mastication and speech. Those present inferior to the geniohyoid muscle, cause a submental swelling that has been described as a double chin
  • 65. THYROGLOSSAL DUCT CYST • It can occur anywhere in the midline along the course of the embryonic thyroglossal duct, (which extends from the foramen caecum of the tongue into the deep fascia near the thyroid isthmus) • Pathognomonic is the movement of the cyst during swallowing and protrusion of the tongue • Complete radical surgical excision of the cyst along with its tract is essential to prevent recurrence.
  • 70. CYSTIC HYGROMA • it is a developmental abnormality, in which cavernous lymphatic spaces communicate and form large thin walled cysts • Typically they appear in the first few months of life • swelling that is painless and compressible, the swelling may increase in size over several months to a year, and they may remain static or may even regress • overlying skin may be bluish and transillumination will be positive • Hygroma may suddenly enlarge when there is an upper respiratory infection. This may cause acute respiratory obstruction and may require an emergency tracheostomy or surgical extirpation
  • 72.
  • 74. Cysts of the jaws, may be treated by one of the following basic methods: 1. Marsupialization (decompression) • Partsch I • Partsch II (combined marsupialization and encleation) • Marsupialization by opening into nose or antrum. 2. Enucleation: • Enucleation and packing • Enucleation and primary closure • Enucleation and primary closure with reconstruction/bone grafting. GENERAL PRINCIPLES OF TREATMENT
  • 80. INDICATIONS FOR MARSUPIALIZATION 1. Age: 2.Proximity to vital structures:. 3.Eruption of teeth: 4.Size of cyst: 5.Vitality of teeth:
  • 81. ADVANTAGES OF MARSUPIALIZATION 1. Simple procedure to perform and reduces operating time 2. Spares vital structures and prevents oronasal and oroantral fistulae 3. Alveolar ridge is preserved and allows eruption of teeth 4. Helps shrinkage of cystic lining and prevents pathological fracture 5. Allows for endosteal bone formation to take place.
  • 82. DISADVANTAGES OF MARSUPIALIZATION 1. Pathologic tissue is left in situ 2.Histologic examination of the entire cystic lining is not done 3. Prolonged healing time and prolonged followup visits 4. Periodic changing of pack, periodic irrigation of cavity 5. Inconvenience to the patient 6. Secondary surgery needed 7. Formation of slit-like pockets that may harbor foodstuffs
  • 83. MODIFICATIONS OF MARSUPIALIZATION PARTSCH II this is a two-stage technique that combines the two standard procedures, in which, first marsupialization is performed and at a later stage when the cavity becomes smaller, the procedure of enucleation is performed and the entire tissue is examined histopathologically
  • 92. ENUCLEATION Indications: 1. Treatment of odontogenic keratocysts 2. Recurrence of cystic lesions
  • 93. ENUCLEATION Advantages: 1. Primary closure of the wound 2. Healing is rapid and postoperative care is reduced 3. Thorough examination of the entire cystic lining can be done.
  • 94. ENUCLEATION Disadvantages: 1. In young persons, the unerupted teeth in a dentigerous cyst will be removed with the lesion 2. Removal of large cysts will weaken the mandible, making it prone to jaw fracture 3. Damage to adjacent vital structures 4. Pulpal necrosis.
  • 95. COMPLICATIONS OF CYSTIC LESIONS 1. Pathological fracture 2. Postoperative wound dehiscence 3. Loss of teeth vitality 4. Neuropraxia in infected cysts 5. Postoperative infection 6. Recurrence in some cysts 7. Dysplastic, neoplastic or even malignant changes
  • 97. SUGGESTED FOLLOW-UP: • Long-term follow-up, at least up to 8 years for keratocysts for early detection of dealing with any recurrence • To check postoperative vitality of teeth • Unerupted teeth that may require orthodontic assistance for eruption • Orthodontic assistance for alignment of displaced teeth • Long-term follow-up of patients with Gorlin's syndrome.