This document presents a case study of a 30-year-old female patient diagnosed with plexiform ameloblastoma based on a biopsy of her right mandible. It provides background on ameloblastoma, describing it as a benign odontogenic tumor arising from odontogenic epithelium. It discusses the various histological subtypes including follicular, plexiform, unicystic (three groups), peripheral, acanthomatous, granular, basal cell, and desmoplastic. Treatment typically involves radical excision, with curettage having the highest recurrence rates. The case study aims to educate on the clinical, radiographic, and histological features of ameloblastoma.
Benign, locally aggressive tumor of odontogenic epithelium, Previously called adamantinoma, Second most common odontogenic tumor after odontoma, Mandible is most common site, Usually asymptomatic and can be found incidentally on routine dental examinations
Fibro-osseous lesions of the jaws
Fibrous dysplasia
Cemento-osseous dysplasia
Focal cemento-osseous dysplasia
Periapical cemento-osseous dysplasia
Florid cemento-osseous dysplasia
Ossifying fibroma
Juvenile aggressive ossifying fibroma
Cherubism
Fibro-osseous lesions (FOL) are characterized by replacement of normal bone architecture by collagen fibers and fibroblasts containing calcified tissue.
They include a wide variety of lesions of developmental, dysplastic and neoplastic origins with clinical and radiographic presentation and behavior.
Because of the histological similarities between diverse diseases, proper diagnosis requires correlation of history, clinical and radiographic findings.Fibrous Dysplasia
2. Reactive (dysplastic lesions arising in the tooth-bearing area (presumably of periodontal origin).
a. Periapical cemento-osseous dysplasia
b. Focal cemento-osseous dysplasia
c. Florid cemento-osseous dysplasia
3. Fibro-osseous neoplasms (widely designated as cementifying fibroma, ossifying fibroma or cemento-ossifying fibroma.Bone dysplasias
a. Fibrous dyspla i. Monostoticii. Polyostotic
iii. Polyostotic with endocrinopathy (McCune-Albright)
iv Osteofibrous dysplasia
b. Osteitis deformansc. Pagetoid heritable bone dysplasias of childhood
d. Segmental odontomaxillary dysplasia
2. Cemento-osseous dysplasias
a. Focal cemento-osseous dysplasia b. Florid cemento-osseous dysplasia
3.Inflammatory/reactive processes
a. Focal sclerosing osteomyelitisb. Diffuse sclerosing osteomyelitis
c. Proliferative periostitis
4. Metabolic Disease: hyperparathyroidism
5. Neoplastic lesions (Ossifying fibromas)
a. Ossifying fibromab. Hyperparathyroidism jaw lesion syndrome
c. Juvenile ossifying fibroma i. Trabecular typeii. Psammomatoid type
d. Gigantiform cementomas
Benign, locally aggressive tumor of odontogenic epithelium, Previously called adamantinoma, Second most common odontogenic tumor after odontoma, Mandible is most common site, Usually asymptomatic and can be found incidentally on routine dental examinations
Fibro-osseous lesions of the jaws
Fibrous dysplasia
Cemento-osseous dysplasia
Focal cemento-osseous dysplasia
Periapical cemento-osseous dysplasia
Florid cemento-osseous dysplasia
Ossifying fibroma
Juvenile aggressive ossifying fibroma
Cherubism
Fibro-osseous lesions (FOL) are characterized by replacement of normal bone architecture by collagen fibers and fibroblasts containing calcified tissue.
They include a wide variety of lesions of developmental, dysplastic and neoplastic origins with clinical and radiographic presentation and behavior.
Because of the histological similarities between diverse diseases, proper diagnosis requires correlation of history, clinical and radiographic findings.Fibrous Dysplasia
2. Reactive (dysplastic lesions arising in the tooth-bearing area (presumably of periodontal origin).
a. Periapical cemento-osseous dysplasia
b. Focal cemento-osseous dysplasia
c. Florid cemento-osseous dysplasia
3. Fibro-osseous neoplasms (widely designated as cementifying fibroma, ossifying fibroma or cemento-ossifying fibroma.Bone dysplasias
a. Fibrous dyspla i. Monostoticii. Polyostotic
iii. Polyostotic with endocrinopathy (McCune-Albright)
iv Osteofibrous dysplasia
b. Osteitis deformansc. Pagetoid heritable bone dysplasias of childhood
d. Segmental odontomaxillary dysplasia
2. Cemento-osseous dysplasias
a. Focal cemento-osseous dysplasia b. Florid cemento-osseous dysplasia
3.Inflammatory/reactive processes
a. Focal sclerosing osteomyelitisb. Diffuse sclerosing osteomyelitis
c. Proliferative periostitis
4. Metabolic Disease: hyperparathyroidism
5. Neoplastic lesions (Ossifying fibromas)
a. Ossifying fibromab. Hyperparathyroidism jaw lesion syndrome
c. Juvenile ossifying fibroma i. Trabecular typeii. Psammomatoid type
d. Gigantiform cementomas
Odontogenic keratocyst (OKC) is the cyst arising from the cell rests of dental lamina. It can occur anywhere in the jaw, but commonly seen in the posterior part of the mandible. Radiographically, most OKCs are unilocular when presented at the periapex and can be mistaken for radicular or lateral periodontal cyst.
learn about salivary glands lesions in oral cavity. summary of each lesion in flash cards. mucocele can have to represenation depending on the situation. can be extravasation or retention
Odontogenic keratocyst (OKC) is the cyst arising from the cell rests of dental lamina. It can occur anywhere in the jaw, but commonly seen in the posterior part of the mandible. Radiographically, most OKCs are unilocular when presented at the periapex and can be mistaken for radicular or lateral periodontal cyst.
learn about salivary glands lesions in oral cavity. summary of each lesion in flash cards. mucocele can have to represenation depending on the situation. can be extravasation or retention
Odontogenic tumors iii/certified fixed orthodontic courses by Indian dental a...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Odontogenic tumors iv /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Ameloblastoma
1.
2. Dr. Gaurav S. Salunkhe
2nd MDS
Oral & Pathology
Ameloblastoma
Clinical Case Presentaion
3. Introduction
Ameloblastoma – English word amel, meaning
enamel+ the Greek word blastoma meaning
germ.
Odontogenic tumors represent a spectrum of
lesion ranging from malignant(rare) and benign
neoplasm to dental hematomas all arising from
odontogenic residues ie. Odontogenic epithelium
and/or ectomysenchyme.
Occasionally an odontogenic tumor develops
from a pre-existing developmental cyst (AOT,
Ameloblastoma from dentigerous cyst)
4. Biopsy No. 107/13
Date: 25/03/2013
Case No. 884618
Ref.by: Dr. Bharat Department : OS
Name of the Patient: Kosha Gandhi
Age : 30yrs Sex: Female
Chief Complaint: swelling on the right side of lower jaw
since 1 year.
Provisional Diagnosis: Ameloblastoma.
22. DIAGNOSIS
Based on histological features the diagnosis was
given as Plexiform Ameloblastoma.
23. Ameloblastoma
(adamantinoma, adamantoblastoma, multilocular cyst)
It is a true neoplasm of enamel organ type tissue
which does not undergo differentiation to the point of
enamel formation.
Defined as: ‘USUALLY UNICENTRIC,
NONFUNTIONAL, INTERMITTENT IN GROWTH,
ANATOMICALLY BENIGN AND CLINICALLY
PERSISTENT’. By Robinson.
The term ameloblastoma was suggested by Churchill
in 1934 to replace the term Adamantinoma, coined
by Malassez in 1885.
24. Pathogenesis
The earlier workers noted the resemblance
between the odontogenic apparatus and the
ameloblastoma and suggested that the neoplasm
has derived from a portion of this apparatus or
from cells potentially capable of forming dental
tissues.
25. Most authors believed that the ameloblastoma to
be of varied origin, thus the tumor conceivably
may be derived from
1. Cell rest of the enamel organ (remnants of the
dental lamina, Hertwig’s sheath, the epithelial
rest of Malassez).
2. Epithelium of odontogenic cysts. (dentigerous
cyst)
3. Disturbance of developing enamel organ.
4. Basal cell of the surface epithelium of the jaw.
5. Heterotopic epithelium in other parts of the
body, specially the pituitary gland.
27. Unicystic ameloblastoma
The unicystic ameloblastoma represent those cystic
lesion that shows clinical, radiographic, or gross
features of a jaw cyst, but on histologic examination
shows a typically ameloblastic epithelium.
The lining part of the cavity may or may not show
luminal and or mural tumor growth.
It is variant of ameloblastoma comprising of 10% to
15% of all intra bony ameloblastoma.
The exact histogenesis is not clear.
It has been suggested that it arise from as a result of
neoplastic transformation of the epithelial lining of
dentigerous cyst or any other type of dental cyst.
28. A high percentage of these lesions are associated
with impacted tooth and most commonly cited
provisional diagnosis is dentigerous cyst.
The recurrence rate is low, and thus indicating
less aggressive
Unicystic ameloblastoma is characterized by
one or more of the following features:
1. Vickers & Gorlin criteria
2. Nodules of tumor projecting intraluminal.
3. Epithelium proliferating into connective
tissue.
4. Islands of ameloblastoma occurring isolated
in connective tissue wall.
29. In some instances, the ameloblastic epithelium
may be proliferative, with extension of the
ameloblastic epithelium into the lumen of the
cystic cavity. This feature has been termed as
intraluminal proliferation.
This growth resembles Plexiform ameloblastoma,
thus some lesion have been referred to as
Plexiform unicystic ameloblastoma.
30. Ackermann classification of
UA 1988
Group 1- Luminal unicystic ameloblastoma.
Tumor confined to the luminal surface of the cyst.
Group 2- Intra-luminal unicystic ameloblastoma.
Nodular proliferation into the lumen without
infiltration of tumor cells into the connective tissue
wall.
Group 3- Mural unicystic ameloblastoma.
Invasive islands of ameloblastomatous epithelium
in the connective tissue wall not involving the
entire epithelium.
31. Unicystic ameloblastoma
Clinical features:
1. Mostly seen in younger individuals.
2. Mostly seen in mandible.
3. Posterior region. Molar-Ramus region
32. Radiographic features:
1. Well defined, radiolucent lesion, with minimal
peripheral sclerotic border.
2. Mimics dentigerous cyst.
3. Associated with impacted/unerupted 3rd molar.
4. In advance stage thinning of cortical bone can
be seen.
33. Peripheral ameloblastoma
Peripheral ameloblastoma is a uncommon/rare
type of odontogenic tumor.
It develops in the soft tissue of the gingiva and
mucosa.
It exhibits an innocuous clinical behaviour.
It is non-invasive.
It accounts for 1-5% of all ameloblastoma.
34. Peripheral ameloblastoma
Clinical features:
Mostly seen in younger individual.
Males > Females.
Mandible> Maxilla.
Mostly seen in premolar region.
The lesion appears as nodule on the gingiva or
mucosa.
Size ranges from 3mm– 2cm in diameter.
Recurrence is uncommon, except when it is
incompletely excised.
38. Histology
The epithelial component of the neoplasm proliferate
to form disconnected islands, cords, and strands within
the collagenized fibrous connective tissue stroma.
In higher magnification, the darkly staining periphery is
composed of tall columnar cells with hyperchromatic
nucleus.
The nucleus tends to be round/oval in shape, and the
nuclei of the adjacent cell are roughly in the same
location within the cytoplasm.
The nuclei are oriented away from the basement
membrane, with small clear vacuoles between the
nucleus and the basement membrane.
40. Follicular ameloblastoma:
Composed of many small discrete islands of
tumor composed of peripheral layer of cuboidal or
columnar cells.
Nuclei are generally well polarised.
The cells resemble ameloblasts or pre-
ameloblasts.
These enclose a central mass of polyhedral,
loosely arranged cells resembling the stellate
reticulum.
41. Plexiform ameloblastoma:
The ameloblast like cells are arranged in irregular
masses, or more frequently, as a network of
interconnected strands of cells.
Each of these strands is bound by a layer of tall
columnar cells, between these layers may be
found stellate reticulum like cells, these stellate
reticulum like tissue is less prominent in Plexiform
ameloblastoma than in the follicular
ameloblastoma.
42. Acanthomatous ameloblastoma:
The cells occupying the position of the stellate
reticulum undergo squamous metaplasia.
Sometimes with keratin formation in the central
part of the tumor island.
keratin formation
43. Granular ameloblastoma:
There is marked transformation in the cytoplasm
if the cells.
The cytoplasm is very coarse, granular,
eosinophilic.
44. Basal cell type of ameloblastoma:
It resembles the basal cell carcinoma of the skin.
It is rarest histological subtype.
The epithelial cells are more primitive and less
columnar, and are arranged in sheet, no stellate
reticulum like cell are present in the center of the
nest.
45. Desmoplastic ameloblastoma :
Half of the Desmoplastic ameloblastoma are
located in the maxilla, and the vast majority occur
in the anterior or premolar portion of jaws.
This is in contrast to classical type of
ameloblastoma, which are found in the posterior
region of mandible.
Maxillary lesion are more insidious than
mandibular tumors owing to the proximity of vital
structures and maxillary sinus.
Also, the thin cortical bone of the maxilla forms a
weak barrier for the spread of the tumor.
46. Desmoplastic ameloblastoma :
Dense collagen stroma, may be hyalinised or
hypocellular.
Has greater tendency to grow in thin strands and
cords of epithelium rather than island like pattern.
The epithelial component is almost compressed
and fragmented by the dense hyalinised stroma.
The peripheral cells are flattened or cuboidal
rather than tall columnar in appearance.
Central cells are often scanty.
Reverse polarity and subnuclear vacuolisations is
difficult to recognize.
48. Reichart et al.
Follicular type had the highest rate of recurrence,
while acanthomatous type has least rate of
recurrence.
Plexiform is intermediate
49. Treatment
The type of T/t that have been used include
1. Radical excision.
2. Conservative surgical excision.
3. Curettage. ( least desirable – highest rate of
recurrence )
4. Electrocautery.
5. Radiation therapy.
6. Combination of surgery & radiation.
50. REFRENCES:
Text book of oral pathology- Shafer 5th edition.
Text book of oral & maxillofacial pathology-
Neville 3rd edition.
Color atlas of oral pathology- Goro Ishikawa
Manual of oral pathology- Dr. Anand
Tegginamani.