Does your next experiment involve Interleukin 6? This is a presentation about IL-6 intended for scientists who are designing controls and performing immunoassays detecting Interleukin-6. It contains useful info such as Western blot band size, protein expression, and interesting facts. Anti-Interleukin-6 Antibody (PA1700): https://www.bosterbio.com/anti-il-6-antibody-pa1700-boster.html References: Uniprot.org, ProteinAtlas.org, GeneCards, PMC3580035, PMC4107025, PMC5522095, PMC5817102 Learn more about IL-6 (infographic and discussion): https://www.bosterbio.com/bosterbio-gene-info-cards/IL6 Boster Biological Technology Website: www.bosterbio.com Email: support@bosterbio.com

1. www.bosterbio.com
Quick facts, control designs, Western Blot MW.
Info you can use to find the best IL6 antibody.
IL-6 IN 3 MINUTES

2. FACTS
01.
Function, structure, etc.
TISSUES
02.
Expressing tissues/cells
WESTERN BLOT
03.
Expected band sizes
HISTORY
04.
…and medical significance
TABLE OF CONTENTS

3. AlphaFold predicted structure
Image source: https://alphafold.ebi.ac.uk/entry/P05231
● Interleukin 6 (IL-6)
● Cytokine with a wide variety of
biological functions
● Has pro- and anti-
inflammatory properties
● Size: 212 amino acids
● Western blot: ~24 kDa
01. FACTS

4. 02. TISSUES
Image source: https://www.proteinatlas.org/ENSG00000136244-IL6/tissue

5. 8087 images available on PMC:
https://www.ncbi.nlm.nih.gov/pmc/?term=il-6+western+blot&report=imagesdocsum
After reviewing several WB images, we observe one IL-6 band at ~ 24 kDa.
03. IL-6 WESTERN BLOT
PMC3580035 Figure 2 PMC4107025 Figure 3
R&D Systems
AF506
Boster Bio IL-6
Antibody (PA1700,
Rabbit Polyclonal)
PMC5817102
Figure 4
PMC5522095 Figure 6

6. IL-6 was originally identified as a B
cell stimulatory factor initiating IgG
production.
04. HISTORY
Anti-IL6 therapy is a new strategy
in the inflammatory autoimmune
diseases and cancer.
1986 CLINICAL POTENTIAL

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