Does your next experiment involve Lipopolysaccharide binding protein (LBP)? This is a presentation about LBP intended for scientists who are designing controls and performing immunoassays detecting LBP. It contains useful info such as Western blot band size, protein expression, and interesting facts. Anti-LBP Antibody Picoband™ (A00809-1): https://www.bosterbio.com/anti-lbp-picoband-trade-antibody-a00809-1-boster.html References: Uniprot.org, ProteinAtlas.org, PMC3617275, PMC3485520, PMC6945416, PMC8710911 Learn more about LBP (infographic and discussion): https://www.bosterbio.com/bosterbio-gene-info-cards/LBP Boster Biological Technology Website: www.bosterbio.com Email: support@bosterbio.com

1. www.bosterbio.com
LBP IN 3 MINUTES
Quick facts, control designs, Western Blot MW.
Info you can use to find the best LBP antibody.

2. FACTS
01.
Function, structure, etc.
TISSUES
02.
Expressing tissues/cells
WESTERN BLOT
03.
Expected band sizes
SIGNIFICANCE
04.
Clinical potential
TABLE OF CONTENTS

3. ● Lipopolysaccharide-binding
protein (LBP)
● Vital role against bacterial infection
● Binds to lipopolysaccharide (LPS)
● LBP precursor: 481 A As long
○ 25-amino acid long signal peptide
is cleaved to form the active LBP
● Active LBP
○ 456 amino acids long
○ Molecular Weight: ~53 kDa
01. FACTS
AlphaFold predicted structure
Image source: https://alphafold.ebi.ac.uk/entry/P18428

4. 02. TISSUES
Image source: https://www.proteinatlas.org/ENSG00000129988-LBP/tissue

5. 03. LBP WESTERN BLOT
102 images available on PMC:
https://www.ncbi.nlm.nih.gov/pmc?term=lbp+western+blot&report=imagesdocsum
After reviewing several WB images, we expect to see LBP from ~53-67 kDa.
PMC6945416 Figure 3
Boster Bio LBP
Antibody (A00809-1,
Rabbit Polyclonal)
PMC3485520 Figure 6
PMC3617275 Figure 2
PMC8710911 Figure 7

6. LBP interacts with other proteins of
the innate immune system, such as
CD14, TLR2, and TLR4.
04. SIGNIFICANCE
Due to the short half-life of plasma
lipopolysaccharide (LPS), LBP is
used as a biomarker for LPS.
INTERACTIONS BIOMARKER

7. 3942 B Valley Ave
Pleasanton, CA 94566
Tel: (888) 466-3604
Email: support@bosterbio.com
www.bosterbio.com