This document discusses trends in business, technology, life sciences, and work/life shifts that are accelerating change. It covers topics like the global mobility of people, education reform, big data, cloud computing, robots, mobile devices, 3D printing, and increasing transparency. The presentation argues that these trends are happening faster externally than many companies are adapting internally, so companies must change or risk falling behind. It provides examples of new technologies in areas like health monitoring devices, biosensors, genetic sequencing costs, and digital health practices to illustrate the speed and impact of these transformations.