Interferential therapy (IFT) is a transcutaneous electrical stimulation technique developed in the 1950s. It involves applying two medium frequency alternating currents intersecting in the tissues at a low frequency. This produces amplitude modulation and generates a low frequency current for therapeutic purposes. IFT uses higher frequencies than TENS which allows for a more comfortable and tolerable penetration through the skin. It works by modulating the amplitude of the medium frequency currents applied through static, dynamic or bipolar interference methods. The physiological effects include pain relief, muscle stimulation, increased blood flow and edema reduction. Precautions must be taken with certain medical conditions and electrode placement is important.