This document summarizes different types of cells involved in the inflammatory response and various forms of inflammation. It describes phagocytic cells that help fight infection, such as monocytes, macrophages, and neutrophils. It also discusses acute and chronic inflammatory cells. Further, it provides examples of specific types of inflammation like fibrinous pericarditis, lung abscesses, and mucoid inflammation. Throughout, it highlights key cell types and features of different inflammatory conditions.

1. Inflammation

3.  1.Function (phagocytosis)
 •Phagocytic cells
 –Monocytes (histiocytes, macrophages)
 –PNL (particularly neutrophils)
 •Non-phagocytic cells
 –Lymphocytes
 –Plasma cells

4.  Acute Inflammatory Cells
 •PNL
 Chronic Inflammatory Cells
 –Macrophages –Histiocytes –Monocytes
 –Lymphocytes
 –Plasma cells

5. Neutrophils

6. lymphocytes

7. eosinophils

8. Basophils

14. Lymphocytic thyroditis

15. fibroblast
 A fibroblast is a type of
cell that synthesizes the
extracellular matrix and
collagen, the structural
framework (stroma) for
animal tissues, and plays
a critical role in wound
healing.

16. Fibroblast cells

18. Plasma cells
 Plasma cell with distinct
clear perinuclear region
of the cytoplasm
containing a large
number of Golgi bodies

19.  Reticuloendothelial cells are phagocytic; i.e., they can
engulf and destroy bacteria, viruses, and other foreign
substances.
 A histiocyte is an animal cell that is part of the mononuclear
phagocyte system (also known as the reticuloendothelial
system or lymphoreticular system). The mononuclear
phagocytic system is part of the organism's immune system.
The histiocyte is a tissue macrophage or a dendritic cell.

20. Giant cells/
 A giant cell is a mass formed by the union of several
distinct cells (usually macrophages).It can arise in
response to an infection, such as from tuberculosis,
herpes, or HIV, or foreign body.
 Epithelioid cells
Are activated macrophages resembling epithelial cells
elongated, with finely granular, pale eosinophilic (pink)
cytoplasm and central, ovoid nucleus (oval or
elongate), which is less dense than that of a lymphocyte

21. Caseous necrosis

22. Giant cells

23. Epitheloid cells

24. Serous inflamtion

25. Pericardial thickening due to
fibrinous inflammation

26. Fibrinous infammation

27. Fibrinous infammation

28. Heart: fibrinous pericarditis
 This is a classic example
of fibrinous
inflammation involving
the visceral pericardium
(“bread and butter”
pericarditis). Fibrinous
inflammation is due to
increased vessel
permeability leading to
the leakage of a sterile
exudate with fibrin on to
the surface of the heart.

29. Purulent inflammation

30. Lung Abscess
 An abscess is a
collection of pus that
has accumulated
within a tissue
because of an
inflammatory process
in response to either
an infectious process
or other foreign
material.

31. Mucoid or Catarrhal Inflammation
 Mucoid or Catarrhal
Inflammation Illustrated
is an up side-down
section of colon which
exhibits excess secretion
of mucus (M) into the
colonic lumen.

32. Serous inflamation
 disruption of epidermis
at the basal level leaving
a clear-fluid-filled
bullous lesion

35. Normal lung: appears as mostly empty space. Alveoli have thin
walled with a thin epithelial cell
through which oxygen and carbon
dioxide diffuse into the capillary
lumen

40. Sub arachnoid space

41. Normal liver
3. Chronic viral hepatitis
Caused by: Chronic viral hepatitis
(hepatitis B virus)
(Characteristic features)
Chronic inflammatory infiltrate is
limited to the portal area

44. Chronic inflamation

46. What is a Granuloma
 A granuloma is a localized mass of granulation tissue
with aggregations of chronic inflammatory cells

48. Granuloma

50. Granulation tissue