This document summarizes the impact of different sources of docosahexaenoic acid (DHA) and other micronutrients on cognitive development in babies. It finds that intake of DHA and omega-3 fatty acids is very low in Indian diets, especially for vegetarians, increasing risk of low birth weight. While fish is a good source of DHA, concerns about mercury contamination make algal sources of DHA a safer option. The document also reviews evidence that supplementation with DHA, calcium, vitamin D, and vitamin B12 during pregnancy can positively impact outcomes like risk of preeclampsia, gestational diabetes, and birth weight.
DHA plays an important role in brain health throughout life. Studies show that adequate maternal DHA intake during pregnancy and breastfeeding is associated with improved infant development and behavior. DHA supplementation in children and adolescents supports optimal brain and cognitive function. Higher DHA status is also linked to a reduced risk of cognitive decline and conditions like Alzheimer's disease in older adults. While recommendations focus on heart health, the levels suggested may be sufficient to support brain health across all life stages.
Calcium and Vitamin D Supplementation in PregnancySujoy Dasgupta
lectured delivered by Dr Sujoy Dasgupta in the CME on "High Risk Pregnancy" organized by the BOGS (Bengal Obettric snd Gynaecological Society) and Wanburry Pharma
the lecture will explain the benefits of using omega 3 in pediatric neurology cases including the use for normal brain functions development in normal babies, premature babies, GDD , cases with cortical visual defect , ADHD, Autism , and anxiety
omega 3 might be of benefits for children with epilepsy , migraine and stroke
The document discusses omega-3, omega-6, and omega-9 fatty acids, including their main components, plant and seafood sources, functions in the body, role in various health conditions, and deficiency symptoms. It provides details on the differences between plant and marine sources of omega-3s, how omega-3s function in the body including promoting healthy cell membranes and reducing inflammation, and conditions such as cardiovascular disease and depression that omega-3s may help prevent or treat.
Essential fatty acids like DHA and GLA play important roles in pregnancy. DHA is important for fetal brain and eye development. Studies show that DHA supplementation in pregnancy increases birth weight and gestation duration, and may reduce the risk of preeclampsia. GLA supplementation may help prevent pregnancy-induced hypertension by increasing production of vasodilatory prostaglandins. International organizations recommend 300 mg of DHA and 150-300 mg of GLA daily during pregnancy.
The document discusses vitamin D, including its synthesis from sun exposure, its role in various bodily processes, and its potential health benefits. Key points include:
- Vitamin D is synthesized in the skin upon exposure to sunlight and can also be obtained through food and supplements. It plays an important role in bone and immune health.
- Vitamin D receptors are found throughout the body and vitamin D has been shown to regulate gene expression, turning genes on and off. This may explain its wide-ranging effects.
- Studies suggest vitamin D may help reduce the risk of various cancers, heart disease, diabetes, respiratory infections, autoimmune diseases, and mental health conditions like depression. Optimal vitamin D levels are important
Ferrous Bisglycinate is chelated iron form, in which iron is chelated with two amino acids.
Small, stable molecule with no ionic charge
Does not react with other nutrients
Bioavailable (easily absorbed)
Safe
Less gastric upset
Many times pregnant woman neglects her health due to nausea, and changes happening to her body. We need to provide her information why she needs to eat healthy balanced food in frequent intervals. This presentation shows the impact of nutrients on the development of brain.
DHA plays an important role in brain health throughout life. Studies show that adequate maternal DHA intake during pregnancy and breastfeeding is associated with improved infant development and behavior. DHA supplementation in children and adolescents supports optimal brain and cognitive function. Higher DHA status is also linked to a reduced risk of cognitive decline and conditions like Alzheimer's disease in older adults. While recommendations focus on heart health, the levels suggested may be sufficient to support brain health across all life stages.
Calcium and Vitamin D Supplementation in PregnancySujoy Dasgupta
lectured delivered by Dr Sujoy Dasgupta in the CME on "High Risk Pregnancy" organized by the BOGS (Bengal Obettric snd Gynaecological Society) and Wanburry Pharma
the lecture will explain the benefits of using omega 3 in pediatric neurology cases including the use for normal brain functions development in normal babies, premature babies, GDD , cases with cortical visual defect , ADHD, Autism , and anxiety
omega 3 might be of benefits for children with epilepsy , migraine and stroke
The document discusses omega-3, omega-6, and omega-9 fatty acids, including their main components, plant and seafood sources, functions in the body, role in various health conditions, and deficiency symptoms. It provides details on the differences between plant and marine sources of omega-3s, how omega-3s function in the body including promoting healthy cell membranes and reducing inflammation, and conditions such as cardiovascular disease and depression that omega-3s may help prevent or treat.
Essential fatty acids like DHA and GLA play important roles in pregnancy. DHA is important for fetal brain and eye development. Studies show that DHA supplementation in pregnancy increases birth weight and gestation duration, and may reduce the risk of preeclampsia. GLA supplementation may help prevent pregnancy-induced hypertension by increasing production of vasodilatory prostaglandins. International organizations recommend 300 mg of DHA and 150-300 mg of GLA daily during pregnancy.
The document discusses vitamin D, including its synthesis from sun exposure, its role in various bodily processes, and its potential health benefits. Key points include:
- Vitamin D is synthesized in the skin upon exposure to sunlight and can also be obtained through food and supplements. It plays an important role in bone and immune health.
- Vitamin D receptors are found throughout the body and vitamin D has been shown to regulate gene expression, turning genes on and off. This may explain its wide-ranging effects.
- Studies suggest vitamin D may help reduce the risk of various cancers, heart disease, diabetes, respiratory infections, autoimmune diseases, and mental health conditions like depression. Optimal vitamin D levels are important
Ferrous Bisglycinate is chelated iron form, in which iron is chelated with two amino acids.
Small, stable molecule with no ionic charge
Does not react with other nutrients
Bioavailable (easily absorbed)
Safe
Less gastric upset
Many times pregnant woman neglects her health due to nausea, and changes happening to her body. We need to provide her information why she needs to eat healthy balanced food in frequent intervals. This presentation shows the impact of nutrients on the development of brain.
VITAMIN AND MINERAL SUPPLEMENTATION DURING PREGNANCYAboubakr Elnashar
This document provides guidelines on vitamin and mineral supplementation during pregnancy. It recommends routine supplementation with folic acid, iron, and vitamin D for most pregnant women. Excessive supplementation above recommended daily allowances should be avoided, as some vitamins and minerals can be toxic or teratogenic in high amounts. The document reviews the roles, sources, deficiencies, and supplementation recommendations for numerous vitamins and minerals, including fat-soluble and water-soluble vitamins, as well as iron. It emphasizes tailoring supplementation to individual needs and avoiding overtreatment.
Nutrition is essential for proper brain development from conception through childhood. The brain develops most rapidly before age 2, and proper nutrition during this time helps support growth and formation of neural connections. Certain nutrients like proteins, fatty acids, iron and B vitamins are particularly important as they support myelination and function of neurotransmitters. A balanced diet with these key nutrients nourishes the developing brain and can help reduce risk of cognitive and behavioral issues. Breastfeeding provides an ideal form of nutrition for a baby's brain in its first months of life.
Microbiota, Vitamin D Receptor and Autoimmuityfathi neana
1. Vitamins are substances which usually cannot be made by the body itself.
2. The body synthesizes vitamin D from 7-dehydro-cholesterol. Vitamin D is not a vitamin, it is a Gene-Transcriptional-Activator, a paracrine steroid hormone. It is the primary ligand which activate VDR
3. Deactivated VDR causes down regulation of the innate immunity. The burden on adaptive immunity increases creating a state of chronic inflammation with possible maladaptation and autoimmunity
4. What causes VDR deactivation is mostly a state of chronic inflammation caused by the pathogens associated with dysbiosis or leaky gut
5. VDR deactivation lead to Increased 1,25-dihydroxy vitamin-D (calcitriol) as there is no consumption and no breakdown
6. Sunshine, dietry and Ingested Vitamin D are preparing the precursors of 1,25-dihydroxy vitamin-D (calcitriol)in the presence of good liver and kidney function
7. 1,25-dihydroxy vitamin-D (calcitriol) is the active form which act as the primary ligand for VDR
8. Olmesartan, a VDR agonist, restores innate immune activity, allows (slow) recovery from advanced disease.
9. Treatment on the long term should be directed to reactivation of VDR by the Natural Ways that Increase Calcitrol and Vitamin D Receptor Gene Expression
10. restoring a balanced Microbiota and overcoming the leaky gut play a major rule in VDR reactivation
This document discusses cardiovascular diseases (CVDs) and recommends ways to prevent them. It notes that 17.3 million people died from CVDs worldwide in 2008, and deaths could rise to 23.6 million by 2030. CVDs represent 30% of all global deaths. The document recommends stopping tobacco use, engaging in regular physical activity, eating a healthy diet high in omega-3 fatty acids from fish and seafood, and taking an omega-3 supplement if dietary intake is insufficient. It then introduces CaliVita's new highly concentrated omega-3 supplement with increased EPA and DHA.
This document discusses nutrition recommendations during pregnancy. It covers recommended weight gain, dietary allowances, macronutrients including protein, carbohydrates, fat and seafood guidelines. It also discusses micronutrients including vitamin and mineral needs such as folate, iron, iodine and cautions around excess vitamin A intake. Habits around caffeine, pica and alcohol are also covered. The document is authored by Prof. Aboubakr Elnashar from Benha University Hospital in Egypt.
Micronutrient deficiency is common among children globally. At least 50% of children aged 6 months to 5 years suffer from one or more micronutrient deficiencies such as iron, iodine, folate, and vitamin A. The reasons for the high prevalence include inadequate intake of nutritious foods, poor absorption of minerals and vitamins, frequent infections, and consumption of refined foods. Micronutrients play an important role in brain development during the first 1,000 days of life. Complementary feeding starting at 6 months is important to meet increased nutrient needs but current practices in India are often inadequate. Ensuring adequate nutrition through home-made preparations, breastfeeding, and fortified complementary foods can help bridge nutrition
Nutritional Management of Premature InfantsMCH-org-ua
International conference «Actual approaches to the extremely preterm babies: International experience and Ukrainian realities» (Kyiv, Ukraine, March 5-6, 2013)
Breastfeeding Vs. Bottle Feeding - Pros And ConsStarlight Baby
When it comes to choosing between breastfeeding or bottle feeding, there are a lot of similarities, but there are also a lot of differences. In this SlideShare, we'll cover the pros and cons of breastfeeding, and the pros and cons of bottle feeding, helping you decide which is better for you.
Folic acid and vitamin B9, is one of the B vitamins.The recommended daily intake level of folate is 400 micrograms from foods or dietary supplements.Folic acid is used to treat anemia caused by folic acid deficiency.It is also used as a supplement by women during pregnancy to prevent neural tube defects (NTDs) in the baby.
An overview of milk, the difference between breast and formula milk, the types of milk formulas, and some of the diseases prevent the use of certain formulas in babies
Probiotics in diarrhea in India - Special Ref to LrGG Lactobacillus Rhamnosus...Gaurav Gupta
Probiotics in diarrhea in India - Special Ref to LrGG Lactobacillus Rhamnosus GG - june 2018 unobiotic, superflora GG,
Talk taken in Chandigarh in June 2018
The document discusses menopause management options, focusing on phytoestrogens as a natural alternative to hormone replacement therapy (HRT). It notes that phytoestrogens from soy and other plants can act as selective estrogen receptor modulators (SERMs) to provide estrogenic effects without the health risks of HRT. Isoflavones like genistein are the most studied phytoestrogens and may help reduce menopausal symptoms and long-term conditions like osteoporosis and heart disease. The document reviews the sources, types, and pharmacology of various phytoestrogens.
Lifecycle nutrition: Pregnancy and LactationHelen Corless
This document provides information on nutrition during pregnancy and lactation. It discusses the importance of good nutrition prior to conception, key nutrients during pregnancy like folate, iron, and calcium, and weight gain recommendations. It describes fetal development from conception through birth and identifies critical periods like early neural tube development. Risks during pregnancy like gestational diabetes and preeclampsia are also covered. The benefits of breastfeeding for both infant and mother are summarized.
Micronutrient deficiencies in children .pptxAzad Haleem
- Micronutrient deficiencies are a major global health issue affecting children's growth and development. The most common deficiencies are iron, iodine, folate, vitamin A, and zinc.
- Children under 5 and pregnant/breastfeeding women are most vulnerable to micronutrient deficiencies due to higher requirements. Global prevalence is estimated to be over 50% of children aged 6 months to 5 years suffering from one or more micronutrient deficiency.
- Key strategies to address deficiencies include supplementation programs, food fortification, and biofortification of staple crops. Universal salt iodization programs have helped increase iodized salt access to 71% of households globally.
The document discusses vitamin D, describing it as essential for health and important for numerous functions in the body. It outlines that vitamin D helps absorb calcium for strong bones and teeth, and supports immune function, mental health, and may lower risks of various diseases. It recommends getting vitamin D through moderate sun exposure or dietary supplements, and describes an optimal vitamin D blood level range.
The document discusses the importance of nutrition during pregnancy and lactation. It notes that the last two trimesters of pregnancy and first six months of lactation represent a critical period for an infant's growth and development. Inadequate maternal nutrition during this time can negatively impact both mother and fetus, leading to issues like low birth weight, prematurity, and impaired growth and development. Proper nutrition is essential to support the high demands of pregnancy, lactation, and the rapid growth and development of the fetus and infant.
L-carnitine plays a critical role in transporting long-chain fatty acids into mitochondria where they are oxidized to produce energy. It is produced in the liver and kidneys from amino acids but is also obtained through meat consumption. L-carnitine supplementation may benefit male infertility, aging, physical performance, end-stage renal disease, type 2 diabetes, cardiovascular disease, and peripheral arterial disease. Side effects are mild but include nausea and "fishy" odor and it may interact with blood thinners.
Vitamin D deficiency is common worldwide and can cause many health issues. It is involved in calcium absorption and bone health. Deficiency leads to osteomalacia and rickets in children, and increases risk of fractures in adults. It may also play roles in cardiovascular disease, diabetes, cancer prevention, autoimmune disease, pregnancy complications, muscle weakness, and mortality. Treatment involves dietary sources of vitamin D, supplementation, and sunlight exposure.
Prenatal nutrition; nutrient recommendations before, during & after pregnancypharmaindexing
This document discusses prenatal nutrition recommendations before, during, and after pregnancy. It recommends increased intake of proteins, vitamins like folate and iron, minerals like calcium and zinc, and omega-3 fatty acids during pregnancy. Nutrition is especially important in the early stages of pregnancy when organs are developing. The three trimesters of pregnancy and stages of fetal development from embryo to fetus are described. Food hygiene and avoiding foods like soft cheeses, raw eggs and undercooked poultry is advised to reduce risk of foodborne illness. Maintaining a healthy diet and lifestyle can help support healthy fetal development and birth outcomes.
VITAMIN AND MINERAL SUPPLEMENTATION DURING PREGNANCYAboubakr Elnashar
This document provides guidelines on vitamin and mineral supplementation during pregnancy. It recommends routine supplementation with folic acid, iron, and vitamin D for most pregnant women. Excessive supplementation above recommended daily allowances should be avoided, as some vitamins and minerals can be toxic or teratogenic in high amounts. The document reviews the roles, sources, deficiencies, and supplementation recommendations for numerous vitamins and minerals, including fat-soluble and water-soluble vitamins, as well as iron. It emphasizes tailoring supplementation to individual needs and avoiding overtreatment.
Nutrition is essential for proper brain development from conception through childhood. The brain develops most rapidly before age 2, and proper nutrition during this time helps support growth and formation of neural connections. Certain nutrients like proteins, fatty acids, iron and B vitamins are particularly important as they support myelination and function of neurotransmitters. A balanced diet with these key nutrients nourishes the developing brain and can help reduce risk of cognitive and behavioral issues. Breastfeeding provides an ideal form of nutrition for a baby's brain in its first months of life.
Microbiota, Vitamin D Receptor and Autoimmuityfathi neana
1. Vitamins are substances which usually cannot be made by the body itself.
2. The body synthesizes vitamin D from 7-dehydro-cholesterol. Vitamin D is not a vitamin, it is a Gene-Transcriptional-Activator, a paracrine steroid hormone. It is the primary ligand which activate VDR
3. Deactivated VDR causes down regulation of the innate immunity. The burden on adaptive immunity increases creating a state of chronic inflammation with possible maladaptation and autoimmunity
4. What causes VDR deactivation is mostly a state of chronic inflammation caused by the pathogens associated with dysbiosis or leaky gut
5. VDR deactivation lead to Increased 1,25-dihydroxy vitamin-D (calcitriol) as there is no consumption and no breakdown
6. Sunshine, dietry and Ingested Vitamin D are preparing the precursors of 1,25-dihydroxy vitamin-D (calcitriol)in the presence of good liver and kidney function
7. 1,25-dihydroxy vitamin-D (calcitriol) is the active form which act as the primary ligand for VDR
8. Olmesartan, a VDR agonist, restores innate immune activity, allows (slow) recovery from advanced disease.
9. Treatment on the long term should be directed to reactivation of VDR by the Natural Ways that Increase Calcitrol and Vitamin D Receptor Gene Expression
10. restoring a balanced Microbiota and overcoming the leaky gut play a major rule in VDR reactivation
This document discusses cardiovascular diseases (CVDs) and recommends ways to prevent them. It notes that 17.3 million people died from CVDs worldwide in 2008, and deaths could rise to 23.6 million by 2030. CVDs represent 30% of all global deaths. The document recommends stopping tobacco use, engaging in regular physical activity, eating a healthy diet high in omega-3 fatty acids from fish and seafood, and taking an omega-3 supplement if dietary intake is insufficient. It then introduces CaliVita's new highly concentrated omega-3 supplement with increased EPA and DHA.
This document discusses nutrition recommendations during pregnancy. It covers recommended weight gain, dietary allowances, macronutrients including protein, carbohydrates, fat and seafood guidelines. It also discusses micronutrients including vitamin and mineral needs such as folate, iron, iodine and cautions around excess vitamin A intake. Habits around caffeine, pica and alcohol are also covered. The document is authored by Prof. Aboubakr Elnashar from Benha University Hospital in Egypt.
Micronutrient deficiency is common among children globally. At least 50% of children aged 6 months to 5 years suffer from one or more micronutrient deficiencies such as iron, iodine, folate, and vitamin A. The reasons for the high prevalence include inadequate intake of nutritious foods, poor absorption of minerals and vitamins, frequent infections, and consumption of refined foods. Micronutrients play an important role in brain development during the first 1,000 days of life. Complementary feeding starting at 6 months is important to meet increased nutrient needs but current practices in India are often inadequate. Ensuring adequate nutrition through home-made preparations, breastfeeding, and fortified complementary foods can help bridge nutrition
Nutritional Management of Premature InfantsMCH-org-ua
International conference «Actual approaches to the extremely preterm babies: International experience and Ukrainian realities» (Kyiv, Ukraine, March 5-6, 2013)
Breastfeeding Vs. Bottle Feeding - Pros And ConsStarlight Baby
When it comes to choosing between breastfeeding or bottle feeding, there are a lot of similarities, but there are also a lot of differences. In this SlideShare, we'll cover the pros and cons of breastfeeding, and the pros and cons of bottle feeding, helping you decide which is better for you.
Folic acid and vitamin B9, is one of the B vitamins.The recommended daily intake level of folate is 400 micrograms from foods or dietary supplements.Folic acid is used to treat anemia caused by folic acid deficiency.It is also used as a supplement by women during pregnancy to prevent neural tube defects (NTDs) in the baby.
An overview of milk, the difference between breast and formula milk, the types of milk formulas, and some of the diseases prevent the use of certain formulas in babies
Probiotics in diarrhea in India - Special Ref to LrGG Lactobacillus Rhamnosus...Gaurav Gupta
Probiotics in diarrhea in India - Special Ref to LrGG Lactobacillus Rhamnosus GG - june 2018 unobiotic, superflora GG,
Talk taken in Chandigarh in June 2018
The document discusses menopause management options, focusing on phytoestrogens as a natural alternative to hormone replacement therapy (HRT). It notes that phytoestrogens from soy and other plants can act as selective estrogen receptor modulators (SERMs) to provide estrogenic effects without the health risks of HRT. Isoflavones like genistein are the most studied phytoestrogens and may help reduce menopausal symptoms and long-term conditions like osteoporosis and heart disease. The document reviews the sources, types, and pharmacology of various phytoestrogens.
Lifecycle nutrition: Pregnancy and LactationHelen Corless
This document provides information on nutrition during pregnancy and lactation. It discusses the importance of good nutrition prior to conception, key nutrients during pregnancy like folate, iron, and calcium, and weight gain recommendations. It describes fetal development from conception through birth and identifies critical periods like early neural tube development. Risks during pregnancy like gestational diabetes and preeclampsia are also covered. The benefits of breastfeeding for both infant and mother are summarized.
Micronutrient deficiencies in children .pptxAzad Haleem
- Micronutrient deficiencies are a major global health issue affecting children's growth and development. The most common deficiencies are iron, iodine, folate, vitamin A, and zinc.
- Children under 5 and pregnant/breastfeeding women are most vulnerable to micronutrient deficiencies due to higher requirements. Global prevalence is estimated to be over 50% of children aged 6 months to 5 years suffering from one or more micronutrient deficiency.
- Key strategies to address deficiencies include supplementation programs, food fortification, and biofortification of staple crops. Universal salt iodization programs have helped increase iodized salt access to 71% of households globally.
The document discusses vitamin D, describing it as essential for health and important for numerous functions in the body. It outlines that vitamin D helps absorb calcium for strong bones and teeth, and supports immune function, mental health, and may lower risks of various diseases. It recommends getting vitamin D through moderate sun exposure or dietary supplements, and describes an optimal vitamin D blood level range.
The document discusses the importance of nutrition during pregnancy and lactation. It notes that the last two trimesters of pregnancy and first six months of lactation represent a critical period for an infant's growth and development. Inadequate maternal nutrition during this time can negatively impact both mother and fetus, leading to issues like low birth weight, prematurity, and impaired growth and development. Proper nutrition is essential to support the high demands of pregnancy, lactation, and the rapid growth and development of the fetus and infant.
L-carnitine plays a critical role in transporting long-chain fatty acids into mitochondria where they are oxidized to produce energy. It is produced in the liver and kidneys from amino acids but is also obtained through meat consumption. L-carnitine supplementation may benefit male infertility, aging, physical performance, end-stage renal disease, type 2 diabetes, cardiovascular disease, and peripheral arterial disease. Side effects are mild but include nausea and "fishy" odor and it may interact with blood thinners.
Vitamin D deficiency is common worldwide and can cause many health issues. It is involved in calcium absorption and bone health. Deficiency leads to osteomalacia and rickets in children, and increases risk of fractures in adults. It may also play roles in cardiovascular disease, diabetes, cancer prevention, autoimmune disease, pregnancy complications, muscle weakness, and mortality. Treatment involves dietary sources of vitamin D, supplementation, and sunlight exposure.
Prenatal nutrition; nutrient recommendations before, during & after pregnancypharmaindexing
This document discusses prenatal nutrition recommendations before, during, and after pregnancy. It recommends increased intake of proteins, vitamins like folate and iron, minerals like calcium and zinc, and omega-3 fatty acids during pregnancy. Nutrition is especially important in the early stages of pregnancy when organs are developing. The three trimesters of pregnancy and stages of fetal development from embryo to fetus are described. Food hygiene and avoiding foods like soft cheeses, raw eggs and undercooked poultry is advised to reduce risk of foodborne illness. Maintaining a healthy diet and lifestyle can help support healthy fetal development and birth outcomes.
Prenatal nutrition nutrient recommendations before, during & after pregnancypharmaindexing
This document discusses prenatal nutrition recommendations before, during, and after pregnancy. It recommends increased intake of proteins, vitamins like folate and iron, minerals like calcium and zinc, and omega-3 fatty acids during pregnancy. Nutrition is especially important in the early stages of pregnancy when organs are developing. The three trimesters of pregnancy and stages of fetal development from embryo to fetus are described. Food hygiene and avoiding foods like soft cheeses, undercooked meat and raw eggs is advised. Maintaining a healthy weight and lifestyle during pregnancy can improve maternal and infant health outcomes.
Docosahexaenoic acid (DHA) is a crucial fatty acid for proper neurological development in fetuses during pregnancy. However, many American women do not consume enough DHA in their diets or through prenatal supplements. DHA is especially important during the third trimester, as it is transported to the fetus and supports brain and eye development. Supplementation of DHA is recommended during pregnancy to support fetal health.
1) Omega-3 fatty acids, especially DHA, are essential for proper brain and eye development in infants and children. Supplementation during pregnancy and lactation can improve cognitive development and visual acuity in babies.
2) Higher intake of DHA and EPA is associated with reduced risk of depression, cardiovascular disease, and mortality in adults. Increased fish consumption also correlates with lower rates of depression across countries.
3) DHA supplementation can help reduce symptoms of ADHD in children and lower triglyceride levels in adults with hypertriglyceridemia.
This randomized controlled trial evaluated the effects of high-dose docosahexaenoic acid (DHA) supplementation on neurodevelopmental outcomes in preterm infants. The study found that:
1) Overall, high-DHA supplementation did not significantly improve Bayley Mental Development Index (MDI) scores at 18 months corrected age compared to standard DHA supplementation.
2) However, girls who received high-DHA supplementation had significantly higher MDI scores than girls who received standard supplementation.
3) Infants born weighing less than 1250g who received high-DHA supplementation tended to have higher MDI scores, but the difference was not statistically significant after adjustment for confounders.
Recent Advances in of BREAST FEEDING : Dr Sharda Jain Lifecare Centre
This document discusses the importance of breastfeeding and providing human milk to newborns within the first hour after birth, known as the "Golden Hour." It recommends exclusively breastfeeding or providing pasteurized donor human milk during this critical period, as formula feeds are not recommended. Initiating feeding within the Golden Hour provides significant health benefits and can reduce neonatal mortality rates. Challenges to early feeding include caesarean deliveries and ensuring babies receive an adequate volume of milk. New products like NeoLact 70 Prime aim to provide short term human milk-based nutrition for all newborns during the Golden Hour to promote gut health and a smooth transition to breastfeeding.
This document discusses docosahexaenoic acid (DHA) supplementation and its influence on neurocognitive development in infants. It outlines several studies that examined the effects of prenatal and postnatal DHA supplementation through breastmilk. The studies found some benefits of supplementation such as improved language and visual acuity development, but the results were mixed. More research is still needed to determine whether DHA supplementation should be recommended as part of prenatal vitamins.
EAT RIGHT IN PREGNANCY Dr Renu Chawla , Dr Sharda Jain Lifecare Centre
The document discusses the importance of nutrition, especially adequate intake of omega-3 fatty acids like DHA, during pregnancy and the first 1000 days of life. It notes that this period is critical for growth and development. The fetus relies on maternal sources of DHA, which is transferred through the placenta and accumulated rapidly in the brain and eyes during the third trimester. Insufficient DHA intake during pregnancy and breastfeeding can impact the health, development, and future disease risk of both mother and child.
Neurodevelopmental Outcomes Of Preterm Infants Fed HighJerome Alagao
A randomized controlled trial found that preterm infant girls who received a high dose of the omega-3 fatty acid DHA (approximately 1% of total fatty acids) from days 2-4 of life until term-equivalent age had higher scores on the Bayley Mental Development Index at 18 months compared to girls who received a standard DHA dose (approximately 0.3% of total fatty acids). However, high DHA intake did not improve neurodevelopmental outcomes for preterm boys. The study also found some evidence that high DHA improved mental development scores for very preterm infants under 2.8 pounds, but the results were not statistically significant after adjustment. Overall, high DHA intake reduced the risk of mild
This study investigated the level of nutrition knowledge among 400 pregnant Australian women across eight domains related to the Australian Guide to Healthy Eating (AGHE) recommendations for pregnancy. The results showed that over half of the women were unfamiliar with the AGHE recommendations. Detailed analysis revealed misconceptions in areas like standard serving sizes, nutrient contents of foods, fat density, and importance of key nutrients. Demographic factors like education level, income, age, stage of pregnancy, language, and nutrition qualifications significantly affected women's nutrition knowledge scores based on regression analysis. The study highlights poor nutrition knowledge among Australian pregnant women and the need for improved support and education.
The document summarizes a study that assessed mothers' knowledge, attitudes, and practices regarding exclusive breastfeeding of infants admitted to PIMS, Islamabad. The study found that most mothers knew the advantages of breastfeeding and its importance for infant health. However, their practices were mainly influenced by cultural traditions passed down from elders in their families. While knowledge of breastfeeding's benefits was generally good, some mothers lacked understanding of key concepts like the difference between breastfeeding and exclusive breastfeeding or the importance of colostrum. The study identified gaps and misconceptions around exclusive breastfeeding practices that could be addressed through improved education and support for mothers.
Opinions And Practices Of Clinicians Associated With Continuation Of Exclusiv...Biblioteca Virtual
This study examined how clinician opinions and practices are associated with continuation of exclusive breastfeeding. The study prospectively followed 288 low-risk mother-newborn pairs who were breastfeeding at 4 weeks. Mothers completed interviews at 4 and 12 weeks, and their obstetric and pediatric clinicians completed surveys. The primary outcome was exclusive breastfeeding at 12 weeks. The study found that clinicians who recommended formula supplementation if an infant was not gaining weight or who felt their breastfeeding advice was not important were associated with early discontinuation of exclusive breastfeeding. Continued exclusive breastfeeding support from clinicians may help improve breastfeeding rates at 6 months.
A Quasi Experimental Study to Evaluate the Effect of Prefeeding Oral Stimulat...ijtsrd
BackgroundPremature infants are defined as neonates born before 37 weeks gestational age a newborn infant, or neonate, is a baby under 28 days of age. During these first 28 days of life, the baby is at highest risk of dying. It is thus crucial that appropriate feeding and care are provided during this period, both to improve the infant’s chances of survival and to lay the foundations for a healthy life.Objective To evaluate the effect of prefeeding oral stimulation program on oral feeding skills among preterm infants.Material and Methods A quasi experimental approach and pretest posttest control group design was adopted. Purposive sampling technique was used to select 40 preterm infants i.e. 20 in each experimental and control group. In experimental group, intra and peri oral stimulation was given for 3 minutes and 2 minutes on pacifier, 2 times a day at 2 hours intervals for the duration of 4 days and in control group routine care was done. Data collection was done using oral feeding skills assessment scale. The collected data were analyzed by calculating frequency, percentage, mean, standard deviation, chi square, and -‘t’ test.Findings The results revealed that in pre test, there was no statistically significant p 0.05 difference in all levels of feeding skills among preterm infants between experimental and control group but in post test there was statistically significant p 0.05 difference found in mean score of all levels of feeding skills among preterm infants in experimental and control group. The difference between the pre test and post test mean scores of all levels of feeding skills among preterm infants in experimental group was statistically more significant in comparison with control group after provision of 4 days of prefeeding oral stimulation programme. Hence prefeeding oral stimulation programme was found to be effective in improving the oral feeding skills among preterm infants.Conclusion The effect of prefeeding oral stimulation program on oral feeding skills among preterm infants is effective and it helped in the improvement of preterm infants feeding skills. Priya Guleria | Mrs. Poonam Toor | Mrs. Davinder Kaur "A Quasi Experimental Study to Evaluate the Effect of Prefeeding Oral Stimulation Program on Oral Feeding Skills among Preterm Infants in Selected Hospitals, Punjab" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-6 , October 2022, URL: https://www.ijtsrd.com/papers/ijtsrd51975.pdf Paper URL: https://www.ijtsrd.com/medicine/nursing/51975/a-quasi-experimental-study-to-evaluate-the-effect-of-prefeeding-oral-stimulation-program-on-oral-feeding-skills-among-preterm-infants-in-selected-hospitals-punjab/priya-guleria
The document discusses the importance of optimal nutrition for growth and brain development in preterm and low birth weight infants. It notes that the goal of nutrition should be to meet the growth rate of healthy fetuses of the same gestational age. This is critical as brain development is most rapid in the first 1000 days of life. For preterm infants, the brain requires high amounts of nutrients for growth and maturation. Inadequate nutrition can permanently impact brain development and neurodevelopmental outcomes. Human milk is recommended but often requires fortification to provide sufficient nutrients. Different fortification methods aim to optimize growth rates while avoiding risks like necrotizing enterocolitis. New fortifiers containing partially hydrolyzed proteins have shown improved growth outcomes over
The study identified 11 factors that contribute to stunting in children under 5 years old in Putrajaya, Malaysia. The strongest associated factor was complications during pregnancy like intrauterine growth restriction. Other significant factors included mid-parental height less than 150cm, low household income, low birth weight, use of pacifiers, lower maternal education, unemployed fathers, anemia in children, bottle feeding, lack of minimum dietary diversity, and care by babysitters. Addressing these maternal, socioeconomic, childcare and nutritional factors through community interventions and policies could help reduce the high prevalence of stunting in Putrajaya.
Infant Feeding And Feeding Transitions During The First Year Of LifeBiblioteca Virtual
This document summarizes infant feeding patterns during the first year of life based on data from the Infant Feeding Practices Study II. Key findings include:
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Impact of DHA Source on Cognitive development of the baby and other micronutrients Dr Meenakshi Sharma
1. Impact of DHA Source on Cognitive
development of the baby and other
micronutrients
Dr Meenakshi Sharma
MD(AIIMS), FICMCH, FICOG
Consultant Obs&Gynae
Yashoda Superspeciality Hospital
2. Dr Meenakshi Sharma
MBBS(AIIMS), MD (AIIMS), FICMCH
● Consultant Obstetrics & Gynaecology, Yashoda Superspeciality Hospitals & Shanti
Mukund Hospital , Delhi
● Ex Registrar and Senior Research Associate AIIMS
● Former Specialist Dr Hedgewar Arogya Sansthan, Govt NCT Delhi
● Recipient of Dr RD Pandit research prize for Best thesis by FOGSI in 2003
Faculty for workshop & Conferences - (16)
Lectures delivered as faculty - (22)
Publications in International and National Journals– (11)
Abstracts Published – (10)
Scientific Papers Presented in National/International Conferences : 14
Member Affiliated Societies
● Life Member AOGD, FOGSI, Delhi Gynaecologist Forum- East, SFM, Trans Hindon
Gynae Forum
● Founder Member GESI,
5. ◼ The intake of marine fish in Indian diets is very low except in
specific coastal regions, and, therefore, the average intakes of
LC n-3 PUFA are negligible
◼ The dietary recommendations by the ICMR have always stressed on
increasing n-3 PUFA intake in Indian diets; however, it is not quite
clear how that can be achieved.
6. INTAKE OF DHA
◼ Intake in third trimester of pregnancy
o India only 11 mg
o Bangladesh 30 mg/day
o Vegetarian diets provide very little, and vegan diets provide
basically no, preformed LC-PUFA
o DHA supplementation is advisable, and vegetarian sources of
DHA are available.
Ann Nutr Metab. 2014;65(1):49-80
7. 7
◼ In Indian diets, the intake of n-3 LC PUFA is
extremely low
◼ Large population in India is vegetarian
◼ High intake of omega 6/omega 3 fatty acids
◼ One of the probable reason for LBW
10year Long Observational study
Mani indu. International Journal of Epidemiology.2016; 45(2): 523-531
8. 8
• Diets lacking LC n-3 PUFA, low intakes of ALNA were associated with the
lowest birth weights and highest risk for SGA
• Best outcomes were associated with moderately high intakes of
ALNA along with at least a minimal amount of LC n-3 PUFA
Mani indu. International Journal of Epidemiology.2016; 45(2): 523-531
9. RECOMMENDATION OF DHA SUPPLEMENTATION
Authority DHA (mg/d)
National Institute of Health (NIH) 300mg per day of DHA in pregnant
and nursing women
American Academy of Pediatrics
(AAP)
The mother’s diet should include
an average daily intake of
300 mg of the ω-3 long-chain
PUFAs (DHA)
Nutrients. 2018 Apr; 10(4): 416.
Matern Health Neonatol Perinatol. 2017;3:22. Published 2017 Dec 12
10. OMEGA FATTY ACIDS & PREGNANCY
OUTCOME
10
• N= 200 Indian pregnant women included from 1st trimester
• Intervention:
• Omega Fatty acid (300mg/day) + Iron +Calcium
• Control Group : Iron + calcium
• 78.8%supplemented with omega 3
fatty acids had normal birth
weight
• 50% of women not supplemented with
omega 3 fatty acids had
normal birth weight
Anne S et al. Int J Reprod Contracept Obstet Gynecol. 2017 Dec;6(12):5396-5400
11. 11
Birth weight
(gm)
Omega
Supplemented
Group
Control
Group
<2000gm 4.00% 16.00%
2000-2499 17.20% 34.00%
2500-2999 63.60% 15.20%
3000 + 15.20% 3.00%
The results of the study suggest that increased intake of
omega 3 fatty acids can prevent low birth weight
Anne S et al. Int J Reprod Contracept Obstet Gynecol. 2017 Dec;6(12):5396-5400
12. DHA INCREASES GESTATION DAYS
12
• Randomized controlled trial
• N= 347 women
• Intervention:
• Group A: Ordinary egg (33mg DHA)
• Group B: Omega Fatty acid enriched egg (133mg)
• Birth weight of infants in the high-DHA egg group
was 103±64 gm higher than for infants whose
mothers consumed ordinary eggs
6-day longer period of gestation when DHA intake was increased during
the last trimester of pregnancy
Obstet Gynecol 2003;101:469–79
13. EFFECT OF DHA
SUPPLEMENTATION ON MATERNAL
OUTCOME
DHA to Optimize Mother Infant Outcome [DOMInO] trial -
Multicentric RCT
N= 2399 women who were < 21 weeks' gestation with singleton
pregnancies
Intervention: DHA (800mg/day) or Matching vegetable oil capsule from study
entry to birth
◼ In the DHA group, significantly fewer infants were born less than 34 weeks'
gestation but significantly more women were induced or had cesarean
sections because they were postterm.
◼ The clinical significance of these findings is difficult to balance, although the
reduction in preterm birth at less than 34 weeks' gestation was also
associated with fewer low birth weight infants and fewer admissions to
neonatal intensive care in the DHA group.
13
JAMA. 2010;304(15):1675-1683
14. EFFECT OF DHA
SUPPLEMENTATION ON BIRTH
WEIGHT
DHA to Optimize Mother Infant Outcome [DOMInO] trial -
Multicentric RCT
N= 2399 women who were < 21 weeks' gestation with singleton pregnancies
Intervention: DHA (800mg/day) or Matching vegetable oil capsule from study
entry to birth
14
• Mean birth weight was 68gm heavier
in DHA Group
JAMA. 2010;304(15):1675-1683
15. EFFECT OF DHA
SUPPLEMENTATION ON Cognitive
Development
DHA to Optimize Mother Infant Outcome [DOMInO] trial -
Multicenteric RCT
◼ Mean cognitive scores of children from women allocated to the
DHA group did not differ from mean scores of children of women
from the control group, although fewer children from the DHA
group had cognitive scores indicating delayed cognitive
development compared with controls.
15
JAMA. 2010;304(15):1675-1683
16. EFFECT OF DHA
SUPPLEMENTATION ON COGNITIVE
DEVELOPMENT
DHA to Optimize Mother Infant Outcome [DOMInO] trial -
Multicenteric RCT
◼ Mean language scores also did not differ between groups;
◼ However, a significant treatment × sex interaction indicated a
differential response of boys and girls.
◼ Girls from the DHA group had a lower mean language score than girls
from the control group, as well as an increased risk of delayed language
development, and the response of boys did not differ between groups.
For the secondary developmental outcomes, motor development,
social-emotional behavior, and adaptive behavior did not differ between
groups overall, although girls exposed to DHA in utero had poorer
mean adaptive behavior scores than girls from the control group. 16
JAMA. 2010;304(15):1675-1683
17. FISH OIL SUPPLEMENTATION IN
PREGNANCY
Vinding RK et al. BMJ. 2018 Sep 4;362:k3312.
n-3 LCPUFA
supplementation in
the third trimester
of pregnancy
stimulates healthy
somatic growth to
age 6 years
19. The dietary sources of omega-3 fatty acids are from marine sources, fish oil
supplements
Although seafood is a good source of DHA, concerns is about mercury
contamination.
Evidence of fetal neuron-developmental abnormalities was seen in infants
whose mothers consumed known, high amounts of mercury-rich seafood
Methylmercury (MeHg) is an organic form of mercury that can damage the
developing brains of human fetuses.
Mercury enters water sources & is consumed by fishes
DHA from Marine (Fish) Source
Rev Obstet Gynecol. 2008 Fall; 1(4): 162–
169.
Nutritional Health 2.4 (2018): 43-50.
21. OMEGA FATTY ACIDS
◼ Mercury occurs naturally in the environment and
accumulates in the aquatic food chain, including fish,
as methylmercury
◼ Because of this, fish is the main source of
methylmercury in the diet for most people. High
levels of methylmercury can damage the
nervous system
◼ Unborn babies are particularly vulnerable
because their brains are developing very rapidly
◼ Some studies of populations that eat large amounts
of fish have reported a link between consumption of
fish by mothers and subtle developmental delays in
their children
Food Standards Australia and New Zealand.
https://www.foodstandards.gov.au/consumer/chemicals/mercury/documents/mif%20brochure.pdf
22. MeHg
Methylmercury (MeHg) is an
organic form of mercury
It can damage the developing
brains of human foetuses.
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
23. H2O
When Water & Bacteria come in contact with MeHg
MeHg
MeHg
Toxicity
increase
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
24. It enters food chain & when pregnant women
consume marine sourced DHA, even small
toxicity can magnify!
Foetus can develop
Congenital Minimata disease
Fishes consume
MeHg
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
25. Consuming MeHg during pregnancy
Children have neurological issues
MeHg has toxic effects on the nervous
system during embryonic development..
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
26. Human Nervous System begins to form..
Exposure to neurotoxins like MeHg can
lead to abnormalities
3rd week of gestation
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
28. ✔ MeHg alters the cell cycle, preventing cerebellar and cortical neurons from
dividing and proliferating.
✔ Causes Degenerative damage on Purkinje cells, granule cells, and astrocytes,
affecting CNS's function and development, along with impairment of the blood-
brain-barrier.
✔ Impairs Glutathione (GSH) antioxidant systems in newborns. This effect can
damage a newborn's aerobic metabolism. As Neural tubes are not formed
MeHg
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
29. MeHg neurotoxin can transfer to an embryo
through the placenta and because the embryo is
highly susceptible to neurotoxicity, the damage to
the developing nervous system in utero can be
severe…
You have a
choice!
The Embryo project encyclopedia
https://embryo.asu.edu/pages/methylmercury-and-human-embryonic-development
30. VEG DHA
◼ For a long time, marine or fish sources were considered the only source of
DHA and thus unsuitable for vegetarians.
◼ The solution can be found in algal DHA.
◼ Derived from algae instead of fish, algal DHA is well perceived to be a pure,
premium source of DHA that can effectively ensure vegetarians get the vast
health benefits with a higher DHA status.
◼ Algal DHA is SAFE as it is free from Methyl Mercury.
◼ Vegetarian derived DHA is SAFE as it is free from Methyl Mercury which is a
neuro-toxin & can harm the growing foetus!
◼ According to USFDA, Algal DHA is generally recognized as safe (GRAS)
based on scientific procedures.
VEG
https://www.fda.gov/media/134100/download
31. CALCIUM
◼ Most common mineral in the human body
In pregnancy:
◼ supports the growth and development of the foetus
◼ Reduced bone resorption and skeletal loss associated with childbearing
In lactation:
◼ During lactation the oestrogen levels in women decreases making bones
weaker, therefore the intake of calcium during breastfeeding is important
◼ According to NIH & ACOG, 1000 mg of elemental calcium per day is
recommended in pregnancy
http://www.pathophys.org/osteoporosis
Cochrane Database Syst Rev.2014 Jun
24;6:CD001059
National Academies Press (US); 2011
ACOG. Nutrition During Pregnancy. Accessed
7/30/2018.
32. CALCIUM IN PREGNANCY AND LACTATION
Fetus in utero and the neonate
through breast-feeding are dependent
on maternal sources for the total
calcium load
Adequate maternal calcium intake can affect fetal bone
health positively.
Paediatr Perinat Epidemiol.2012 ;26 S1:138-52
Environ Health Perspect. 2009; 117(1): 26–31
Am J Obstet Gynecol. 2006 ;194(4):937-45
33. MEETING FETAL CALCIUM DEMAND
• At adequate levels of vitamin D, the calcium demands of
the mother and fetus are met through increased
intestinal calcium absorption
• Severe vitamin D deficiency with secondary
hyperparathyroidism during pregnancy leads to
abnormal calcium homeostasis in the neonate
34. Who are at risk of vitamin D
deficiency?
All of us
35. Infants born to mothers with hypovitaminosis D had 3.8
times higher risk of developing hypovitaminosis D as
compared to those born to mothers with normal vitamin D
levels
J Pediatr Endocrinol Metab. 2009 Mar;22(3):241-6
96.3 % of the lactating Indian women had vitamin D
deficiency. Serum 25(OH)D levels were significantly lower in
winter in the second and third trimesters
Br J Nutr. 2011 Nov;106(9):1383-9.
Mothers of babies who suffer hypocalcaemic seizures are more
likely to be vitamin D deficient (85%) than mothers of
babies who do not (50%)
Indian Pediatr 2010;47:581–6
Maternal vitamin D deficiency is potentially preventable with vitamin D
supplementation
36. ◼ 22 trials involving 3725 pregnant women were included
◼ Supplementation with vitamin D alone during pregnancy probably reduces the risk of
o pre-eclampsia (risk ratio (RR) 0.48, 95% confidence interval (CI) 0.30 to 0.79; 4
trials, 499 women, moderate-certainty evidence) and
o gestational diabetes (RR 0.51, 95% CI 0.27 to 0.97; 4 trials, 446 women,
moderate-certainty probably reduces the risk of
o low birthweight (less than 2500 g) (RR 0.55, 95% CI 0.35 to 0.87; 5 trials,697
women, moderate-certainty evidence) compared to women who received placebo or
no intervention
◼ Supplementing pregnant women with vitamin D alone probably reduces the risk of pre-
eclampsia, gestational diabetes, low birthweight and may reduce the risk of severe
postpartum haemorrhage
Cochrane Database of Systematic Reviews 2019, Issue 7. Art. No.: CD008873. DOI: 10.1002/14651858.CD008873.pub4.
37. VITAMIN B12
◼ Demand increases during pregnancy due to rapid
cell multiplication resulting from the uterine
enlargement, placental development and fetal
growth
◼ Its secretion into breast milk is highly dependent
on current maternal intake and absorption
◼ Its deficiency can lead to poor fetal growth, brain
development, pregnancy outcome
Siddiqua et al., J Nutr Disorders Ther 2014, 4:2
H. Van Sande et al. Journal of Obstetrics and Gynecology 3 (2013) 599-
602
38. B VITAMINS
◼ Indian mothers have high homocysteine concentrations due to dietary
deficiencies (vitamin B12 and protein)
◼ Folic acid supplementation in pregnancy reduces the neural tube defects
◼ Vitamin B6 is crucial for the healthy function of the brain and nervous system
and thus plays a critical role in the development of baby
J Prenat Med. 2008 Oct-Dec; 2(4): 40–41
Asia Pac J Clin Nutr 2005;14 (2):179-181
H. Van Sande et al. Open Journal of Obstetrics and Gynecology 3 (2013)
599-602
Nutrients 2016, 8, 68
39. TAKE HOME MESSAGE
◼ The first 1000 days of life represents the time from pregnancy
through the child’s second birthday
◼ Optimal nutrition status during pregnancy is critical, as it
impacts early embryonic development, organogenesis and
neural development.
◼ Calcium, vitamin D, DHA and Folic acid plays important role in
both maternal and fetal health
◼ Long chain fatty acids are essential for the growth and
functional development of the brain in infants
40. TAKE HOME MESSAGE
◼ DHA is important for normal brain functions, the development of visual and
neural tissues and subsequently motor and cognitive development.
◼ DHA - Increases gestation length, enhance fetal and placental growth further
reduces the risk of complications
◼ Evidence of fetal neuron-developmental abnormalities was seen in infants
whose mothers consumed known, high amounts of mercury-rich seafood.
◼ MeHg neurotoxin can transfer to an embryo through the placenta and
because the embryo is highly susceptible to neurotoxicity, the damage to the
developing nervous system in utero can be severe
◼ Vegetarian derived DHA is SAFE as it is free from Methyl Mercury which is a
neuro-toxin & can harm the growing foetus!