This document analyzes the performance of a 6KW 45V PEM fuel cell stack through simulations varying the pressure of reactants (hydrogen and oxygen) and operating temperature. The simulations show that increasing the pressure of hydrogen from 1 bar to 2 bar, while keeping oxygen pressure and temperature constant, reduces hydrogen consumption from 78 liters per minute to 38 liters per minute. Increasing oxygen pressure from 1 bar to 2 bar, while keeping hydrogen pressure and temperature constant, reduces oxygen consumption from 180 liters per minute to 85 liters per minute. Increasing the operating temperature from 320K to 350K, while keeping reactant pressures constant, greatly reduces both hydrogen and oxygen consumption.