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Organ that pumps blood, circulating it to all
parts of the body
The human heart is a four-chambered
double pump with its right and left sides
fully separated by a septum and
subdivided on both sides into an atrium
above and a ventricle below. The right
atrium receives venous blood from the
superior and inferior venae cavae (see
vena cava) and propels it into the
pulmonary circulation. The left atrium takes
in blood from the pulmonary veins and
sends it into the systemic circulation.
Electrical signals from a natural pacemaker
cause the heart muscle to contract. Valves
in the heart keep blood flowing in one
direction. Their snapping shut after each
contraction causes the sounds heard as
the heartbeat. See also cardiovascular
system.
Structure of the human heart.
Oxygen-rich blood from the lungs
enters the heart through the
pulmonary veins, passing into the
left atrium and on to the left
ventricle. Contraction of the
muscles of the left ventricle forces
blood into the aorta. The mitral
valve prevents blood from moving
back into the left atrium during
contraction. Various arteries branch
off from the aorta to supply blood to
all parts of the body. Oxygen-poor
blood draining from the body into
the superior vena cava and inferior
vena cava flows to the right atrium,
through the tricuspid valve, and into
the right ventricle. As the right
ventricle contracts, oxygen-poor
blood passes through the
pulmonary valve into the pulmonary
arteries and on to the lungs to
receive oxygen.
Process by which nutrients, respiratory gases, and metabolic products
are transported throughout the body.
In humans, blood remains within a closed cardiovascular system
composed of the heart, blood vessels, and blood. Arteries carry
blood away from the heart under high pressure exerted by the
heart's pumping action. Arteries divide into smaller arterioles, which
branch into a network of tiny capillaries with thin walls across which
gases and nutrients diffuse. Capillaries rejoin into larger venules,
which unite to form veins, which carry blood back to the heart. (See
artery; capillary; vein.) The right and left heart chambers send blood
into separate pulmonary and systemic circulations. In the first, blood
is carried from the heart to the lungs, where it picks up oxygen and
releases carbon dioxide; in the second, blood is carried between the
heart and the rest of the body, where it carries oxygen, nutrients,
metabolic products, and wastes.
Human circulatory system. Oxygen-rich
blood is shown in red, oxygen-poor blood
in blue. The pulmonary circulation consists
of the right ventricle and the exiting
pulmonary artery and its branches, the
arterioles, capillaries, and venules of the
lung, and the pulmonary vein. Unlike the
other arteries and veins, the pulmonary
arteries carry deoxygenated blood and the
pulmonary veins carry oxygenated blood.
The aorta arises from the left ventricle. The
brachiocephalic artery arises from the
aorta and divides into the right common
carotid and right subclavian arteries. The
left and right common carotids extend on
either side of the neck and supply much of
the head and neck. The left subclavian
artery (arising from the aorta) and the right
subclavian artery supply the arms. In the
lower abdomen, the aorta divides into the
common iliac arteries, which give rise to
external and internal branches supplying
the legs.
Either of two light, spongy, elastic organs in the chest, used for
breathing.
Each is enclosed in a membrane (pleura). Contraction of the
diaphragm and the muscles between the ribs draw air into the
lungs through the trachea, which splits into two primary
bronchi, one per lung. Each bronchus branches into
secondary bronchi (one per lobe of lung), tertiary bronchi (one
per segment of lung), and many bronchioles leading to the
pulmonary alveoli. There oxygen in the inspired gas is
exchanged for carbon dioxide from the blood in the
surrounding capillaries. Adequate tissue oxygen supply
depends on sufficient distribution of air (ventilation) and blood
(perfusion) in the lungs. Lung injuries or diseases (e.g.,
emphysema, embolism, pneumonia) can affect either or both.
In humans, the diaphragm and, to a lesser extent,
the muscles between the ribs generate a pumping
action, moving air in and out of the lungs through a
system of pipes (conducting airways), divided into
upper and lower airway systems. The upper
airway system comprises the nasal cavity (see
nose), sinuses, and pharynx; the lower airway
system consists of the larynx, trachea, bronchi,
bronchioles, and alveolar ducts (see pulmonary
alveolus). The blood and cardiovascular system
can be considered elements of a working
respiratory system. See also thoracic cavity.
As air enters the nasal cavity through the nostrils, it is warmed and moistened by mucous
membranes of the nasal turbinates before entering the pharynx. Stiff hairs lining the vestibule inside
the nostrils help filter the entering air. The air-filled sinuses adjacent to the nasal cavity produce
mucus. The larynx connects the pharynx with the trachea or windpipe. The cartilaginous epiglottis
prevents food from entering the larynx during swallowing. A left and right primary bronchus supply
each lung with air from the trachea. They divide into smaller secondary and tertiary bronchi; the
smallest divisions, bronchioles, lead to the cup-shaped, thin-walled alveoli, which occur in clusters
(alveolar sacs). Oxygen and carbon dioxide are exchanged between the alveoli and surrounding
capillaries. Oblique fissures or grooves of each lung separate the upper lobe from the lower lobe.
The horizontal, or transverse, fissure of the right lung forms a middle lobe. Movement of the
diaphragm along with the ribs and rib muscles causes expansion and contraction of the lungs
during breathing.
Process of dissolving and chemically converting food for absorption by cells.
In the mouth, food is chewed, mixed with saliva, which begins to break down
starches, and kneaded by the tongue into a ball for swallowing. Peristalsis
propels it through the esophagus and the rest of the alimentary canal. In the
stomach, food mixes with acid and enzymes, which further break it down.
The mixture, called chyme, enters the duodenum, the first part of the small
intestine. Bile from the liver breaks up fat globules. Enzymes from the
pancreas and intestinal glands act on specific molecules, breaking
carbohydrates down into simple sugars, proteins into amino acids, and fats
into glycerol and fatty acids. These products are absorbed by the
bloodstream. Indigestible substances, such as fibre, pass into the large
intestine, where water and ions are reabsorbed and feces held for excretion.
Major organs of the human digestive system. Food
taken in by the mouth is guided by the tongue as it is
sheared and ground by the teeth. The bolus of
chewed food is moistened and lubricated with saliva
secreted by the salivary glands. Enzymes in the
saliva begin the breakdown of starches. The
epiglottis, a flap of tissue, prevents food from the
pharynx from entering the larynx during swallowing.
Muscles in the esophagus wall contract in waves to
move the food to the stomach. Gastric juices
secreted by the stomach contain a mixture of
substances (including enzymes and hydrochloric
acid) that break down the food into a semiliquid mass
called chyme. The chyme passes into the small
intestine, where food molecules are broken down into
sugars, amino acids, and fatty acids. These useful
substances are absorbed into the bloodstream as the
food passes through the duodenum, jejunum, and
ileum. The pancreas secretes digestive enzymes into
the duodenum. The liver secretes bile salts that make
insoluble fats entering the small intestine water-
soluble and vulnerable to enzymatic action. Excess
bile salts are stored in the gallbladder. The large
intestine (colon) serves to remove water and
electrolytes from the digested chyme and to compact
and store undigestible material, called feces. Fecal
matter is moved by muscular contractions into the
rectum and expelled from the anus.
Hollow, tubular structure connecting the pharynx with the
trachea, through which air passes on the way to the
lungs.
The larynx consists of a framework of cartilage plates, with
a ridge in front (Adam's apple); the epiglottis, a flaplike
projection up into the throat that covers the airway during
swallowing to keep food and liquid from entering; and the
vocal cords, whose vibration produces the sound of the
voice
(A) Frontal view and (B) cutaway
side view of the human larynx. The
larynx is composed of cartilage
plates that are joined together by
muscles and ligaments. The thyroid
cartilage, the largest, forms a
prominence in front called the
Adam's apple. The leaf-shaped
epiglottis, attached to the upper
part of the thyroid cartilage, closes
during swallowing. The vocal cords
in the cavity of the larynx are large
folds in the mucous membrane
lining the larynx. They stretch
between the thyroid cartilage in
front and the arytenoids cartilages
in the back. As air passes between
them, they vibrate to emit sound.
One of a pair of organs that maintain water balance and expel
metabolic wastes.
Human kidneys are bean-shaped organs about 4 in. (10 cm) long, in
the small of the back. They filter the entire 5-quart (about 4.5-liter)
water content of the blood every 45 minutes. Glucose, minerals, and
needed water are returned to the blood by reabsorption. The
remaining fluid and wastes pass into collecting ducts, flowing to the
ureter and bladder as urine. Each kidney has over 1 million
functional units (nephrons) involved in the process of filtration and
reabsorption. The kidneys also secrete renin, an enzyme involved in
blood pressure regulation. Disorders include kidney failure, kidney
stones, and nephritis
Cross section of a kidney. The kidney is
made up of an outermost cortex, a middle
medulla, and an inner pelvis. Blood enters
via the renal artery, which branches into
smaller vessels, each of which terminates
in a tuft of capillaries (glomerulus). Fluids
from the blood are forced out of the
glomerulus into the surrounding Bowman's
capsule during filtration. The glomerulus,
Bowman's capsule, and associated renal
tubule make up the nephron. Any important
substances filtered from the blood
(including glucose, minerals, and much of
the water) are returned to it by reabsorption
in the renal tubule. The medulla is divided
into conical masses of tissue (renal
pyramids) that contain the collecting ducts
for the fluid (urine) not reabsorbed into the
blood. Water is further removed from the
urine as it passes through the collecting
ducts into the funnel-shaped renal pelvis,
which leads to the ureter.
System that produces and discharges urine to rid the body of
waste products.
It consists of the kidneys, which balance electrolytes in blood,
retaining and adding needed ones and removing unneeded or
dangerous ones for excretion; the ureters, two thin muscular
tubes 10–12 in. (25–30 cm) long that move the urine by
peristalsis; the hollow, muscular bladder, which receives and
stores it; and the urethra, through which it leaves the body. In
women the urethra is 1.5 in. (4 cm) long. In men it is longer
(since it passes through the penis), about 8 in. (20 cm), and
carries semen from the prostate gland as well as urine.
Urinary disorders, which can lead to dehydration or edema
and to a dangerous buildup of waste and toxic substances,
include kidney failure, tumours, and bladder and kidney
stones.
Group of ductless glands that secrete hormones necessary for normal
growth and development, reproduction, and homeostasis.
The major endocrine glands are the hypothalamus, pituitary, pineal,
thyroid, parathyroids, adrenals, islets of Langerhans in the pancreas,
ovaries, and testes. Secretion is regulated either by regulators in a
gland that detect high or low levels of a chemical and inhibit or
stimulate secretion or by a complex mechanism involving the
hypothalamus and the pituitary. Tumours that produce hormones
can throw off this balance. Diseases of the endocrine system result
from over- or underproduction of a hormone or an abnormal
response to a hormone.
Major glands of the human endocrine system.
The hypothalamus stimulates the pituitary
gland and influences food intake, weight
regulation, fluid intake and balance, thirst,
body heat, and the sleep cycle. Pituitary
hormones stimulate growth, egg and sperm
development, milk secretion, and release of
hormones by other glands. The pineal gland
may play a significant role in sexual maturation
and the circadian rhythm. Thyroid hormones
regulate the metabolic rate of tissues,
stimulate the contraction of heart muscle, and
are necessary for normal growth and brain
development before birth and during infancy.
Parathyroid hormone regulates calcium,
phosphorus, and magnesium levels. The
adrenal glands regulate salt and water
retention, some reactions of the immune
system, and blood pressure. The islets of
Langerhans regulate blood sugar levels. The
ovaries and testes produce hormones that
regulate the reproductive system and that
produce male and female secondary sex
characteristics.
Concentration of nerve tissue in the front or upper end
of a body.
It handles sensory information, controls motion, is vital
to instinctive acts, and in higher vertebrates is the
centre of learning. Vertebrate brains consist of the
hindbrain (rhombencephalon), midbrain
(mesencephalon), and forebrain (prosencephalon).
The hindbrain comprises the medulla oblongata and
the pons, which connects the spinal cord with higher
brain levels and transfers information from the cerebral
cortex to the cerebellum. The midbrain, a major
sensory integration centre in other vertebrates, serves
primarily to link the hindbrain and forebrain in
mammals. Large nerve bundles connect the
cerebellum to the medulla, pons, and midbrain. In the
forebrain the two cerebral hemispheres are connected
by a thick bundle of nerve fibres (corpus callosum) and
are divided by two deep grooves into four lobes
(frontal, parietal, temporal, and occipital). The
cerebrum, the largest part of the human brain, is
involved with its more complex functions. Motor and
sensory nerve fibres from each hemisphere cross over
in the medulla to control the opposite side of the body.
Side view of the brain showing its major
structures. The large cerebrum is divided into two
halves, or hemispheres, connected by the corpus
callosum, a band of nerve fibres. Two grooves
divide the hemispheres into four lobes: frontal,
temporal, parietal, and occipital. Many nerve cells
are found in the convoluted cerebrum's outer
surface, or cerebral cortex, which controls sensory
and motor activities. The thalamus relays
incoming sensory impulses from the spinal cord to
the cortex. The hypothalamus's many functions
include control of breathing, blood flow,
temperature regulation, and emotions. The
pituitary gland is attached to and regulated by the
hypothalamus. The midbrain relays signals
between the forebrain and hindbrain. The
cerebellum, along with the cerebrum, plays a role
in voluntary movement as well as balance. The
pons serves as a relay point linking the medulla
oblongata, midbrain, cerebellum, and cerebrum.
The medulla, lying between the pons and the
spinal cord and continuous with both, plays a role
in essential involuntary regulatory and reflexive
responses (including breathing, swallowing, and
heartbeat) and relays signals between the spinal
cord and other brain regions
Largest part of the brain.
The two cerebral hemispheres consist of an inner core of
myelinated nerve fibres, the white matter, and a heavily
convoluted outer cortex of gray matter (see cerebral cortex).
Nerve fibres in the white matter connect functional areas of
the cortex in the same hemispheres, connect functional areas
of the cortex in opposite hemispheres, and connect the
cerebral cortex to lower centres (e.g., the spinal cord). A front-
to-back fissure divides the cerebrum's two hemispheres. Each
hemisphere controls the opposite side of the body. The
corpus callosum, a thick band of white matter, connects them,
allowing integration of sensory data and responses from both
sides of the body. Other important cerebral structures include
the hypothalamus and the thalamus.
Part of the brain that integrates sensory input from the
inner ear and from proprioceptors in muscle with nerve
impulses from the cerebrum (see cerebral cortex),
coordinating muscle responses to maintain balance and
produce smooth, coordinated movements.
Located below the cerebral hemispheres and behind the
upper medulla oblongata and pons, each of its two
connected hemispheres has a core of white matter within
a cortex of gray matter. Disorders usually produce
neuromuscular disturbances, in particular ataxia.
Organ that receives light and visual images.
Non-image forming, or direction, eyes are found among worms, mollusks, cnidarians, echinoderms,
and other invertebrates; image-forming eyes are found in certain mollusks, most arthropods, and
nearly all vertebrates. Arthropods are unique in possessing a compound eye, which results in their
seeing a multiple image that is partially integrated in the brain. Lower vertebrates such as fish
have eyes on either side of the head, allowing a maximum view of the surroundings but producing
two separate fields of vision. In predatory birds and mammals, binocular vision became more
important. Evolutionary changes in the placement of the eyes permitted a larger overlap of the two
visual fields, resulting in the higher mammals in a parallel line of direct sight. The human eye is
roughly spherical. Light passes through its transparent front and stimulates receptor cells on the
retina (cones for colour vision, rods for black-and-white vision in faint light), which in turn send
impulses through the optic nerve to the brain. Vision disorders include near- and farsightedness
and astigmatism (correctable with eyeglasses or contact lenses), colour blindness, and night
blindness. Other eye disorders (including detached retina and glaucoma) can cause visual-field
defects or blindness
Structure of the human eye. The outer portion
consists of the white protective sclera and
transparent cornea, through which light enters.
The middle layer includes the blood-supplying
choroid and pigmented iris. Light passing into
the interior through the pupil is regulated by
muscles that control the pupil's size. The
retina comprises the third layer and contains
receptor cells (rods and cones) that transform
light waves into nervous impulses. The lens,
lying directly behind the iris, focuses light onto
the retina. The macula lutea, in the centre of
the retina, is a region of high visual acuity and
colour discrimination. Nerve fibres pass out
through the optic nerve to the brain's visual
centre. The eye's anterior and posterior
chambers contain a watery fluid that nourishes
the cornea and lens. The vitreous humour
helps maintain the eye's shape. A thin layer of
mucous membrane (conjunctiva) protects the
eye's exposed surface. External muscles,
including the medial rectus and lateral rectus
muscles, connect and move the eye in its
socket.
Any of the hard structures in the mouth used for biting and chewing and in
speech.
Each consists of a crown above the gum and one or more roots below it,
embedded in the jaw. Its inner pulp contains the blood and nerve supply for
the bonelike dentin, covered in the crown by enamel, the hardest tissue in
the body. Twenty primary (baby) teeth come in by age 2 1/2 and fall out
between ages 5 and 13 to be replaced by 32 permanent teeth. The incisors,
in front, are shaped mostly for biting, the pointed canines for tearing, and
the premolars and molars for grinding food. The teeth are subject to caries
(decay), caused by acid from bacteria in plaque, a yellowish film that builds
up on teeth. Misalignment of teeth between the upper and lower jaws can
grind down the teeth and cause problems in chewing. Elsewhere, it is a
cosmetic problem. Both can be treated with braces
Cross section of an adult molar. The
crown (the part of the tooth above the
gum) is protected by a hard outer
layer of enamel. The roots sit in a
socket in the jawbone and are
covered with cementum, a bonelike
material. The periodontal ligament
anchors the cementum in the jaw and
cushions the tooth from the
pressures of chewing. The tooth's
main portion, the dentin, surrounds
the soft pulp, which carries the blood
vessels and nerves. Specialized cells
of the pulp project threadlike
extensions into the dentin through
narrow channels and serve to form
new dentin from minerals in the
blood.
Human body

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Human body

  • 1.
  • 2.
  • 3. Organ that pumps blood, circulating it to all parts of the body The human heart is a four-chambered double pump with its right and left sides fully separated by a septum and subdivided on both sides into an atrium above and a ventricle below. The right atrium receives venous blood from the superior and inferior venae cavae (see vena cava) and propels it into the pulmonary circulation. The left atrium takes in blood from the pulmonary veins and sends it into the systemic circulation. Electrical signals from a natural pacemaker cause the heart muscle to contract. Valves in the heart keep blood flowing in one direction. Their snapping shut after each contraction causes the sounds heard as the heartbeat. See also cardiovascular system.
  • 4. Structure of the human heart. Oxygen-rich blood from the lungs enters the heart through the pulmonary veins, passing into the left atrium and on to the left ventricle. Contraction of the muscles of the left ventricle forces blood into the aorta. The mitral valve prevents blood from moving back into the left atrium during contraction. Various arteries branch off from the aorta to supply blood to all parts of the body. Oxygen-poor blood draining from the body into the superior vena cava and inferior vena cava flows to the right atrium, through the tricuspid valve, and into the right ventricle. As the right ventricle contracts, oxygen-poor blood passes through the pulmonary valve into the pulmonary arteries and on to the lungs to receive oxygen.
  • 5. Process by which nutrients, respiratory gases, and metabolic products are transported throughout the body. In humans, blood remains within a closed cardiovascular system composed of the heart, blood vessels, and blood. Arteries carry blood away from the heart under high pressure exerted by the heart's pumping action. Arteries divide into smaller arterioles, which branch into a network of tiny capillaries with thin walls across which gases and nutrients diffuse. Capillaries rejoin into larger venules, which unite to form veins, which carry blood back to the heart. (See artery; capillary; vein.) The right and left heart chambers send blood into separate pulmonary and systemic circulations. In the first, blood is carried from the heart to the lungs, where it picks up oxygen and releases carbon dioxide; in the second, blood is carried between the heart and the rest of the body, where it carries oxygen, nutrients, metabolic products, and wastes.
  • 6. Human circulatory system. Oxygen-rich blood is shown in red, oxygen-poor blood in blue. The pulmonary circulation consists of the right ventricle and the exiting pulmonary artery and its branches, the arterioles, capillaries, and venules of the lung, and the pulmonary vein. Unlike the other arteries and veins, the pulmonary arteries carry deoxygenated blood and the pulmonary veins carry oxygenated blood. The aorta arises from the left ventricle. The brachiocephalic artery arises from the aorta and divides into the right common carotid and right subclavian arteries. The left and right common carotids extend on either side of the neck and supply much of the head and neck. The left subclavian artery (arising from the aorta) and the right subclavian artery supply the arms. In the lower abdomen, the aorta divides into the common iliac arteries, which give rise to external and internal branches supplying the legs.
  • 7. Either of two light, spongy, elastic organs in the chest, used for breathing. Each is enclosed in a membrane (pleura). Contraction of the diaphragm and the muscles between the ribs draw air into the lungs through the trachea, which splits into two primary bronchi, one per lung. Each bronchus branches into secondary bronchi (one per lobe of lung), tertiary bronchi (one per segment of lung), and many bronchioles leading to the pulmonary alveoli. There oxygen in the inspired gas is exchanged for carbon dioxide from the blood in the surrounding capillaries. Adequate tissue oxygen supply depends on sufficient distribution of air (ventilation) and blood (perfusion) in the lungs. Lung injuries or diseases (e.g., emphysema, embolism, pneumonia) can affect either or both.
  • 8. In humans, the diaphragm and, to a lesser extent, the muscles between the ribs generate a pumping action, moving air in and out of the lungs through a system of pipes (conducting airways), divided into upper and lower airway systems. The upper airway system comprises the nasal cavity (see nose), sinuses, and pharynx; the lower airway system consists of the larynx, trachea, bronchi, bronchioles, and alveolar ducts (see pulmonary alveolus). The blood and cardiovascular system can be considered elements of a working respiratory system. See also thoracic cavity.
  • 9. As air enters the nasal cavity through the nostrils, it is warmed and moistened by mucous membranes of the nasal turbinates before entering the pharynx. Stiff hairs lining the vestibule inside the nostrils help filter the entering air. The air-filled sinuses adjacent to the nasal cavity produce mucus. The larynx connects the pharynx with the trachea or windpipe. The cartilaginous epiglottis prevents food from entering the larynx during swallowing. A left and right primary bronchus supply each lung with air from the trachea. They divide into smaller secondary and tertiary bronchi; the smallest divisions, bronchioles, lead to the cup-shaped, thin-walled alveoli, which occur in clusters (alveolar sacs). Oxygen and carbon dioxide are exchanged between the alveoli and surrounding capillaries. Oblique fissures or grooves of each lung separate the upper lobe from the lower lobe. The horizontal, or transverse, fissure of the right lung forms a middle lobe. Movement of the diaphragm along with the ribs and rib muscles causes expansion and contraction of the lungs during breathing.
  • 10. Process of dissolving and chemically converting food for absorption by cells. In the mouth, food is chewed, mixed with saliva, which begins to break down starches, and kneaded by the tongue into a ball for swallowing. Peristalsis propels it through the esophagus and the rest of the alimentary canal. In the stomach, food mixes with acid and enzymes, which further break it down. The mixture, called chyme, enters the duodenum, the first part of the small intestine. Bile from the liver breaks up fat globules. Enzymes from the pancreas and intestinal glands act on specific molecules, breaking carbohydrates down into simple sugars, proteins into amino acids, and fats into glycerol and fatty acids. These products are absorbed by the bloodstream. Indigestible substances, such as fibre, pass into the large intestine, where water and ions are reabsorbed and feces held for excretion.
  • 11. Major organs of the human digestive system. Food taken in by the mouth is guided by the tongue as it is sheared and ground by the teeth. The bolus of chewed food is moistened and lubricated with saliva secreted by the salivary glands. Enzymes in the saliva begin the breakdown of starches. The epiglottis, a flap of tissue, prevents food from the pharynx from entering the larynx during swallowing. Muscles in the esophagus wall contract in waves to move the food to the stomach. Gastric juices secreted by the stomach contain a mixture of substances (including enzymes and hydrochloric acid) that break down the food into a semiliquid mass called chyme. The chyme passes into the small intestine, where food molecules are broken down into sugars, amino acids, and fatty acids. These useful substances are absorbed into the bloodstream as the food passes through the duodenum, jejunum, and ileum. The pancreas secretes digestive enzymes into the duodenum. The liver secretes bile salts that make insoluble fats entering the small intestine water- soluble and vulnerable to enzymatic action. Excess bile salts are stored in the gallbladder. The large intestine (colon) serves to remove water and electrolytes from the digested chyme and to compact and store undigestible material, called feces. Fecal matter is moved by muscular contractions into the rectum and expelled from the anus.
  • 12. Hollow, tubular structure connecting the pharynx with the trachea, through which air passes on the way to the lungs. The larynx consists of a framework of cartilage plates, with a ridge in front (Adam's apple); the epiglottis, a flaplike projection up into the throat that covers the airway during swallowing to keep food and liquid from entering; and the vocal cords, whose vibration produces the sound of the voice
  • 13. (A) Frontal view and (B) cutaway side view of the human larynx. The larynx is composed of cartilage plates that are joined together by muscles and ligaments. The thyroid cartilage, the largest, forms a prominence in front called the Adam's apple. The leaf-shaped epiglottis, attached to the upper part of the thyroid cartilage, closes during swallowing. The vocal cords in the cavity of the larynx are large folds in the mucous membrane lining the larynx. They stretch between the thyroid cartilage in front and the arytenoids cartilages in the back. As air passes between them, they vibrate to emit sound.
  • 14. One of a pair of organs that maintain water balance and expel metabolic wastes. Human kidneys are bean-shaped organs about 4 in. (10 cm) long, in the small of the back. They filter the entire 5-quart (about 4.5-liter) water content of the blood every 45 minutes. Glucose, minerals, and needed water are returned to the blood by reabsorption. The remaining fluid and wastes pass into collecting ducts, flowing to the ureter and bladder as urine. Each kidney has over 1 million functional units (nephrons) involved in the process of filtration and reabsorption. The kidneys also secrete renin, an enzyme involved in blood pressure regulation. Disorders include kidney failure, kidney stones, and nephritis
  • 15. Cross section of a kidney. The kidney is made up of an outermost cortex, a middle medulla, and an inner pelvis. Blood enters via the renal artery, which branches into smaller vessels, each of which terminates in a tuft of capillaries (glomerulus). Fluids from the blood are forced out of the glomerulus into the surrounding Bowman's capsule during filtration. The glomerulus, Bowman's capsule, and associated renal tubule make up the nephron. Any important substances filtered from the blood (including glucose, minerals, and much of the water) are returned to it by reabsorption in the renal tubule. The medulla is divided into conical masses of tissue (renal pyramids) that contain the collecting ducts for the fluid (urine) not reabsorbed into the blood. Water is further removed from the urine as it passes through the collecting ducts into the funnel-shaped renal pelvis, which leads to the ureter.
  • 16. System that produces and discharges urine to rid the body of waste products. It consists of the kidneys, which balance electrolytes in blood, retaining and adding needed ones and removing unneeded or dangerous ones for excretion; the ureters, two thin muscular tubes 10–12 in. (25–30 cm) long that move the urine by peristalsis; the hollow, muscular bladder, which receives and stores it; and the urethra, through which it leaves the body. In women the urethra is 1.5 in. (4 cm) long. In men it is longer (since it passes through the penis), about 8 in. (20 cm), and carries semen from the prostate gland as well as urine. Urinary disorders, which can lead to dehydration or edema and to a dangerous buildup of waste and toxic substances, include kidney failure, tumours, and bladder and kidney stones.
  • 17. Group of ductless glands that secrete hormones necessary for normal growth and development, reproduction, and homeostasis. The major endocrine glands are the hypothalamus, pituitary, pineal, thyroid, parathyroids, adrenals, islets of Langerhans in the pancreas, ovaries, and testes. Secretion is regulated either by regulators in a gland that detect high or low levels of a chemical and inhibit or stimulate secretion or by a complex mechanism involving the hypothalamus and the pituitary. Tumours that produce hormones can throw off this balance. Diseases of the endocrine system result from over- or underproduction of a hormone or an abnormal response to a hormone.
  • 18. Major glands of the human endocrine system. The hypothalamus stimulates the pituitary gland and influences food intake, weight regulation, fluid intake and balance, thirst, body heat, and the sleep cycle. Pituitary hormones stimulate growth, egg and sperm development, milk secretion, and release of hormones by other glands. The pineal gland may play a significant role in sexual maturation and the circadian rhythm. Thyroid hormones regulate the metabolic rate of tissues, stimulate the contraction of heart muscle, and are necessary for normal growth and brain development before birth and during infancy. Parathyroid hormone regulates calcium, phosphorus, and magnesium levels. The adrenal glands regulate salt and water retention, some reactions of the immune system, and blood pressure. The islets of Langerhans regulate blood sugar levels. The ovaries and testes produce hormones that regulate the reproductive system and that produce male and female secondary sex characteristics.
  • 19.
  • 20. Concentration of nerve tissue in the front or upper end of a body. It handles sensory information, controls motion, is vital to instinctive acts, and in higher vertebrates is the centre of learning. Vertebrate brains consist of the hindbrain (rhombencephalon), midbrain (mesencephalon), and forebrain (prosencephalon). The hindbrain comprises the medulla oblongata and the pons, which connects the spinal cord with higher brain levels and transfers information from the cerebral cortex to the cerebellum. The midbrain, a major sensory integration centre in other vertebrates, serves primarily to link the hindbrain and forebrain in mammals. Large nerve bundles connect the cerebellum to the medulla, pons, and midbrain. In the forebrain the two cerebral hemispheres are connected by a thick bundle of nerve fibres (corpus callosum) and are divided by two deep grooves into four lobes (frontal, parietal, temporal, and occipital). The cerebrum, the largest part of the human brain, is involved with its more complex functions. Motor and sensory nerve fibres from each hemisphere cross over in the medulla to control the opposite side of the body.
  • 21. Side view of the brain showing its major structures. The large cerebrum is divided into two halves, or hemispheres, connected by the corpus callosum, a band of nerve fibres. Two grooves divide the hemispheres into four lobes: frontal, temporal, parietal, and occipital. Many nerve cells are found in the convoluted cerebrum's outer surface, or cerebral cortex, which controls sensory and motor activities. The thalamus relays incoming sensory impulses from the spinal cord to the cortex. The hypothalamus's many functions include control of breathing, blood flow, temperature regulation, and emotions. The pituitary gland is attached to and regulated by the hypothalamus. The midbrain relays signals between the forebrain and hindbrain. The cerebellum, along with the cerebrum, plays a role in voluntary movement as well as balance. The pons serves as a relay point linking the medulla oblongata, midbrain, cerebellum, and cerebrum. The medulla, lying between the pons and the spinal cord and continuous with both, plays a role in essential involuntary regulatory and reflexive responses (including breathing, swallowing, and heartbeat) and relays signals between the spinal cord and other brain regions
  • 22. Largest part of the brain. The two cerebral hemispheres consist of an inner core of myelinated nerve fibres, the white matter, and a heavily convoluted outer cortex of gray matter (see cerebral cortex). Nerve fibres in the white matter connect functional areas of the cortex in the same hemispheres, connect functional areas of the cortex in opposite hemispheres, and connect the cerebral cortex to lower centres (e.g., the spinal cord). A front- to-back fissure divides the cerebrum's two hemispheres. Each hemisphere controls the opposite side of the body. The corpus callosum, a thick band of white matter, connects them, allowing integration of sensory data and responses from both sides of the body. Other important cerebral structures include the hypothalamus and the thalamus.
  • 23. Part of the brain that integrates sensory input from the inner ear and from proprioceptors in muscle with nerve impulses from the cerebrum (see cerebral cortex), coordinating muscle responses to maintain balance and produce smooth, coordinated movements. Located below the cerebral hemispheres and behind the upper medulla oblongata and pons, each of its two connected hemispheres has a core of white matter within a cortex of gray matter. Disorders usually produce neuromuscular disturbances, in particular ataxia.
  • 24. Organ that receives light and visual images. Non-image forming, or direction, eyes are found among worms, mollusks, cnidarians, echinoderms, and other invertebrates; image-forming eyes are found in certain mollusks, most arthropods, and nearly all vertebrates. Arthropods are unique in possessing a compound eye, which results in their seeing a multiple image that is partially integrated in the brain. Lower vertebrates such as fish have eyes on either side of the head, allowing a maximum view of the surroundings but producing two separate fields of vision. In predatory birds and mammals, binocular vision became more important. Evolutionary changes in the placement of the eyes permitted a larger overlap of the two visual fields, resulting in the higher mammals in a parallel line of direct sight. The human eye is roughly spherical. Light passes through its transparent front and stimulates receptor cells on the retina (cones for colour vision, rods for black-and-white vision in faint light), which in turn send impulses through the optic nerve to the brain. Vision disorders include near- and farsightedness and astigmatism (correctable with eyeglasses or contact lenses), colour blindness, and night blindness. Other eye disorders (including detached retina and glaucoma) can cause visual-field defects or blindness
  • 25. Structure of the human eye. The outer portion consists of the white protective sclera and transparent cornea, through which light enters. The middle layer includes the blood-supplying choroid and pigmented iris. Light passing into the interior through the pupil is regulated by muscles that control the pupil's size. The retina comprises the third layer and contains receptor cells (rods and cones) that transform light waves into nervous impulses. The lens, lying directly behind the iris, focuses light onto the retina. The macula lutea, in the centre of the retina, is a region of high visual acuity and colour discrimination. Nerve fibres pass out through the optic nerve to the brain's visual centre. The eye's anterior and posterior chambers contain a watery fluid that nourishes the cornea and lens. The vitreous humour helps maintain the eye's shape. A thin layer of mucous membrane (conjunctiva) protects the eye's exposed surface. External muscles, including the medial rectus and lateral rectus muscles, connect and move the eye in its socket.
  • 26. Any of the hard structures in the mouth used for biting and chewing and in speech. Each consists of a crown above the gum and one or more roots below it, embedded in the jaw. Its inner pulp contains the blood and nerve supply for the bonelike dentin, covered in the crown by enamel, the hardest tissue in the body. Twenty primary (baby) teeth come in by age 2 1/2 and fall out between ages 5 and 13 to be replaced by 32 permanent teeth. The incisors, in front, are shaped mostly for biting, the pointed canines for tearing, and the premolars and molars for grinding food. The teeth are subject to caries (decay), caused by acid from bacteria in plaque, a yellowish film that builds up on teeth. Misalignment of teeth between the upper and lower jaws can grind down the teeth and cause problems in chewing. Elsewhere, it is a cosmetic problem. Both can be treated with braces
  • 27. Cross section of an adult molar. The crown (the part of the tooth above the gum) is protected by a hard outer layer of enamel. The roots sit in a socket in the jawbone and are covered with cementum, a bonelike material. The periodontal ligament anchors the cementum in the jaw and cushions the tooth from the pressures of chewing. The tooth's main portion, the dentin, surrounds the soft pulp, which carries the blood vessels and nerves. Specialized cells of the pulp project threadlike extensions into the dentin through narrow channels and serve to form new dentin from minerals in the blood.