Over millions of years, social abilities – such as bonding, empathy, compassion, language, and cooperative planning – really aided survival. Love, broadly defined, has profoundly shaped the evolution of the human brain.
Steadying the Mind - Healing and Treating Trauma, Addictions and Related Diso...Rick Hanson
To stay alive in the wild, our ancestors evolved highly distractible attentional systems – which pose real challenges to developing greater mindfulness today. This presentation covers how attention works in your brain, and the implications of normal neurological diversity for the “turtles” and “jackrabbits” at either end of the spectrum.
Introduction to the neuroscience of mindfulness and meditation; brain-wise methods for steadying the mind, quieting it, bringing it to singleness, and concentrating it; an exploration of what could be happening in the brain during the non-ordinary states of consciousness
Buddha's Brain: Lighting Up the Neural Circuits of Happiness, Love and WisdomRick Hanson
Combining the power of the latest brain science with the wisdom of contemplative practice, these are practical methods for centering your brain in its natural state of gladness, love, and peace.
Neuropsychological research on stress, emotions, and painful experiences; approach/avoid responses to the pleasant/unpleasant “hedonic tone” of experience; illuminating parallels in the Buddhist analysis of “dependent origination,” in which our reactions to the hedonic tone of experience lead to craving, clinging, and suffering; numerous methods for reducing or eliminating reactions to the hedonic tone, and thus gaining much greater emotional balance, and an increasingly unshakeable core of happiness.
More resources are freely offered at http://www.rickhanson.net.
Taking in the Good: Building Resilience into the Brain through Positive Exper...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
Presented at Spirit Rock Meditation Center - December, 2011.
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
Steadying the Mind - Healing and Treating Trauma, Addictions and Related Diso...Rick Hanson
To stay alive in the wild, our ancestors evolved highly distractible attentional systems – which pose real challenges to developing greater mindfulness today. This presentation covers how attention works in your brain, and the implications of normal neurological diversity for the “turtles” and “jackrabbits” at either end of the spectrum.
Introduction to the neuroscience of mindfulness and meditation; brain-wise methods for steadying the mind, quieting it, bringing it to singleness, and concentrating it; an exploration of what could be happening in the brain during the non-ordinary states of consciousness
Buddha's Brain: Lighting Up the Neural Circuits of Happiness, Love and WisdomRick Hanson
Combining the power of the latest brain science with the wisdom of contemplative practice, these are practical methods for centering your brain in its natural state of gladness, love, and peace.
Neuropsychological research on stress, emotions, and painful experiences; approach/avoid responses to the pleasant/unpleasant “hedonic tone” of experience; illuminating parallels in the Buddhist analysis of “dependent origination,” in which our reactions to the hedonic tone of experience lead to craving, clinging, and suffering; numerous methods for reducing or eliminating reactions to the hedonic tone, and thus gaining much greater emotional balance, and an increasingly unshakeable core of happiness.
More resources are freely offered at http://www.rickhanson.net.
Taking in the Good: Building Resilience into the Brain through Positive Exper...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
Presented at Spirit Rock Meditation Center - December, 2011.
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
The Negativity Bias and Taking in the GoodRick Hanson
The brain's evolved bias is like Velcro for negative experiences, but Teflon for positive ones. The unfortunate results include stress and threat reactivity, anxiety, depression, and limited gains in psychotherapy. Happily, through tree steps of mindful attention, we can internalize positive experiences in implicit memory systems, weaving resources for well-being, coping, and kindness into the fabric of the barin and the self.
Taking in the Good: Helping Children Build Inner Strength and HappinessRick Hanson
Scientists believe the brain evolved a "negativity bias" that makes it like Velcro for negative experiences but Teflon for positive ones. This helped our ancestors survive, but it's bad for children (and parents) today - leading them to overreact, hold onto hurts and resentments, and have a harder time developing inner resources. To address this challenge, this presentation will use practical neuroscience to show how to weave positive experiences into the fabric of the brain and the self - including how to pair a positive experience with a negative one to heal old pain.
Rick Hanson gave this public lecture for the Bridging the Hearts and Minds of Youth: Mindfulness in Clinical Practice, Education and Research Conference at the UCSD Center for Mindfulness in February, 2012.
The Neurology of Awakening: Using the New Brain Research to Steady Your MindRick Hanson
Introduction to the neuroscience of mindfulness and meditation; brain-wise methods for steadying the mind, quieting it, bringing it to singleness, and concentrating it; an exploration of what could be happening in the brain during the non-ordinary states of consciousness known as samadhis or jhanas.
More resources, freely offered at http://www.rickhanson.net
Managing the Caveman Brain in the 21st CenturyRick Hanson
The human brain evolved in three stages: reptile, mammal, and primate. Each stage has a core motivation: avoid harm, approach reward, and attach to "us." Modern life challenges these ancient neural systems with bombardments of threat messages, the endless stimulation of desire, and social disconnections and tensions of industrial, multicultural societies. This talk will explore brain-savvy ways to cultivate mindfulness in young people, and then use that mindfulness to internalize a greater sense of strength and safety, contentment, and being loved.
Rick Hanson gave this keynote address for the Bridging the Hearts and Minds of Youth: Mindfulness in Clinical Practice, Education and Research Conference at the UCSD Center for Mindfulness in February, 2012.
Using the Mind To Change the Brain: Talks @Google - Rick Hanson, PhDRick Hanson
Jesus, Moses, the Buddha, and other great teachers were all born with a brain built essentially like anyone else's. Then they used their minds to change their brains in ways that changed history. With the new breakthroughs in neuroscience, combined with insights from thousands of years of contemplative practice, you, too, can shape your own brain for greater happiness, love, and wisdom.
Written with neurologist Richard Mendius, M.D., and with a Foreword by Daniel Siegel, M.D. and a Preface by Jack Kornfield, Ph.D., Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom joins modern science with ancient teachings to show you how to have greater emotional balance in turbulent times, as well as healthier relationships, more effective actions, and greater peace of mind.
http://amzn.to/oLTD3B
Pairing Positive and Negative to Fill the Hole in the HeartRick Hanson
Implicit memory systems – including expectations, emotional residues and reactive patterns – are a primary target of therapy. Since they are vulnerable to change during consolidation, the skillful pairing of positive and negative material in awareness can gradually soothe and ultimately replace negative implicit memories. This workshop will explore neuro-savvy methods for doing this, including how to identify the positive material that will best "antidote" old pain or deficits in internalized resources.
Taking in the Good: Weaving Positive Emotions, Optimism and Resilience into t...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
Paper Tiger Paranoia - Rick Hanson, PhDRick Hanson
How the brain’s “negativity bias” makes clients overestimate threats, underestimate opportunities, and underestimate inner and outer resources, leading to anxiety, anger, depression, and conflicts with others – and how to help clients overcome that bias, see the good facts about the others, the world, and themselves, and build resilience for happiness, healthy relationships, and occupational success.
More resources are freely offered at http://www.rickhanson.net.
Buddha's Brain: Lighting up Your Own Circuits of Happiness, Love, and Wisdom ...Rick Hanson
How mental activity sculpts neural structure; the benefits and pitfalls of integrating neuroscience and psychotherapy; the neural substrates of self-compassion; and how to activate the lateral networks of mindful awareness.
More resources, freely offered at http://www.rickhanson.net
Being and Doing: Activating Neural Networks of Mindful Presence - Rick Hanson...Rick Hanson
In our turbocharged culture, "doing" routinely overpowers "being," so this talk and discussion covers effective ways to stimulate and strengthen "being networks: the neural substate of spacious contented awareness."
More resources, freely offered at http://www.rickhanson.net
Self -Directed Neuroplasticity: Using the New Brain Research to Deepen Clinic...Rick Hanson
How mental activity sculpts neural structure; the benefits and pitfalls of integrating neuroscience and psychotherapy; the neural substrates of self-compassion; and how to activate the lateral networks of mindful awareness.
Natural Contentment And Brain Evolution - Rick Hanson, PhDRick Hanson
With the power of modern neuroscience, informed by ancient contemplative wisdom, you can use your mind alone to change your brain for the better. Self-directed neuroplasticity involves steadying the mind (key to both worldly success and spiritual practice), cooling the fires of stress reactivity, weaving positive experiences into the fabric of your brain and self, and taking life less personally.
More resources are freely offered at http://www.rickhanson.net.
Mindfulness and Taking in the Good: Using Neuroplasticity to Weave Resources ...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
The Whole Holy Brain: Activating Integrative Processes in Your Nervous System...Rick Hanson
How you can use your mind to reshape your brain for the better, plus three specific ways to promote integrative processes in your brain.
More resources, freely offered at http://www.rickhanson.net
Not-Self in the Brain: Insights from Neuroscience about Not Taking Life Perso...Rick Hanson
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
More resources, freely offered at http://www.rickhanson.net
New science is showing how mental activity sculpts neural structure. Using the power of self-directed neuroplasticity, you can target, stimulate, and thus gradually strengthen the neural substrates of well-being.
More resources are freely offered at http://www.rickhanson.net.
Buddha's Brain: Natural Enlightenment and Unshakable Peace - Rick Hanson, PhDRick Hanson
Combining the power of the latest brain science with the wisdom of contemplative practice, this workshop will present practical methods for centering your brain in its natural state of gladness, love, and peace. In particular, you'll learn brain-savvy ways to reduce anxiety and irritability, feel stronger and safer, and clear old pain.
More resources are freely offered at http://www.rickhanson.net.
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
More resources, freely offered at http://www.rickhanson.net
Buddha's Brain: The Practical Neuroscience of Inner Peace - Rick Hanson, PhDRick Hanson
Integrate the latest brain science research with the ancient wisdom of contemplative practice. Discover practical methods for improving mindfulness and concentration, calming the heart, weaving positive experiences into your brain and your self, and then bringing these new strengths into your relationships with both kindness and assertiveness.
More resources are freely offered at http://www.rickhanson.net.
The Negativity Bias and Taking in the GoodRick Hanson
The brain's evolved bias is like Velcro for negative experiences, but Teflon for positive ones. The unfortunate results include stress and threat reactivity, anxiety, depression, and limited gains in psychotherapy. Happily, through tree steps of mindful attention, we can internalize positive experiences in implicit memory systems, weaving resources for well-being, coping, and kindness into the fabric of the barin and the self.
Taking in the Good: Helping Children Build Inner Strength and HappinessRick Hanson
Scientists believe the brain evolved a "negativity bias" that makes it like Velcro for negative experiences but Teflon for positive ones. This helped our ancestors survive, but it's bad for children (and parents) today - leading them to overreact, hold onto hurts and resentments, and have a harder time developing inner resources. To address this challenge, this presentation will use practical neuroscience to show how to weave positive experiences into the fabric of the brain and the self - including how to pair a positive experience with a negative one to heal old pain.
Rick Hanson gave this public lecture for the Bridging the Hearts and Minds of Youth: Mindfulness in Clinical Practice, Education and Research Conference at the UCSD Center for Mindfulness in February, 2012.
The Neurology of Awakening: Using the New Brain Research to Steady Your MindRick Hanson
Introduction to the neuroscience of mindfulness and meditation; brain-wise methods for steadying the mind, quieting it, bringing it to singleness, and concentrating it; an exploration of what could be happening in the brain during the non-ordinary states of consciousness known as samadhis or jhanas.
More resources, freely offered at http://www.rickhanson.net
Managing the Caveman Brain in the 21st CenturyRick Hanson
The human brain evolved in three stages: reptile, mammal, and primate. Each stage has a core motivation: avoid harm, approach reward, and attach to "us." Modern life challenges these ancient neural systems with bombardments of threat messages, the endless stimulation of desire, and social disconnections and tensions of industrial, multicultural societies. This talk will explore brain-savvy ways to cultivate mindfulness in young people, and then use that mindfulness to internalize a greater sense of strength and safety, contentment, and being loved.
Rick Hanson gave this keynote address for the Bridging the Hearts and Minds of Youth: Mindfulness in Clinical Practice, Education and Research Conference at the UCSD Center for Mindfulness in February, 2012.
Using the Mind To Change the Brain: Talks @Google - Rick Hanson, PhDRick Hanson
Jesus, Moses, the Buddha, and other great teachers were all born with a brain built essentially like anyone else's. Then they used their minds to change their brains in ways that changed history. With the new breakthroughs in neuroscience, combined with insights from thousands of years of contemplative practice, you, too, can shape your own brain for greater happiness, love, and wisdom.
Written with neurologist Richard Mendius, M.D., and with a Foreword by Daniel Siegel, M.D. and a Preface by Jack Kornfield, Ph.D., Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom joins modern science with ancient teachings to show you how to have greater emotional balance in turbulent times, as well as healthier relationships, more effective actions, and greater peace of mind.
http://amzn.to/oLTD3B
Pairing Positive and Negative to Fill the Hole in the HeartRick Hanson
Implicit memory systems – including expectations, emotional residues and reactive patterns – are a primary target of therapy. Since they are vulnerable to change during consolidation, the skillful pairing of positive and negative material in awareness can gradually soothe and ultimately replace negative implicit memories. This workshop will explore neuro-savvy methods for doing this, including how to identify the positive material that will best "antidote" old pain or deficits in internalized resources.
Taking in the Good: Weaving Positive Emotions, Optimism and Resilience into t...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
Paper Tiger Paranoia - Rick Hanson, PhDRick Hanson
How the brain’s “negativity bias” makes clients overestimate threats, underestimate opportunities, and underestimate inner and outer resources, leading to anxiety, anger, depression, and conflicts with others – and how to help clients overcome that bias, see the good facts about the others, the world, and themselves, and build resilience for happiness, healthy relationships, and occupational success.
More resources are freely offered at http://www.rickhanson.net.
Buddha's Brain: Lighting up Your Own Circuits of Happiness, Love, and Wisdom ...Rick Hanson
How mental activity sculpts neural structure; the benefits and pitfalls of integrating neuroscience and psychotherapy; the neural substrates of self-compassion; and how to activate the lateral networks of mindful awareness.
More resources, freely offered at http://www.rickhanson.net
Being and Doing: Activating Neural Networks of Mindful Presence - Rick Hanson...Rick Hanson
In our turbocharged culture, "doing" routinely overpowers "being," so this talk and discussion covers effective ways to stimulate and strengthen "being networks: the neural substate of spacious contented awareness."
More resources, freely offered at http://www.rickhanson.net
Self -Directed Neuroplasticity: Using the New Brain Research to Deepen Clinic...Rick Hanson
How mental activity sculpts neural structure; the benefits and pitfalls of integrating neuroscience and psychotherapy; the neural substrates of self-compassion; and how to activate the lateral networks of mindful awareness.
Natural Contentment And Brain Evolution - Rick Hanson, PhDRick Hanson
With the power of modern neuroscience, informed by ancient contemplative wisdom, you can use your mind alone to change your brain for the better. Self-directed neuroplasticity involves steadying the mind (key to both worldly success and spiritual practice), cooling the fires of stress reactivity, weaving positive experiences into the fabric of your brain and self, and taking life less personally.
More resources are freely offered at http://www.rickhanson.net.
Mindfulness and Taking in the Good: Using Neuroplasticity to Weave Resources ...Rick Hanson
How the brain evolved a “negativity bias” that continually looks for, reacts to, and stores negative experiences; how this shapes the interior landscape of the mind, leading to pessimism, depressed and anxious mood, and over-reactions; the neural machinery of memory; how to “trick” that machinery into weaving positive experiences into the brain and the self, leading to greater resilience, happiness, and interpersonal effectiveness; applications to particular situations, including healing trauma, cooperation with medical or psychological treatment, and raising or teaching children.
The Whole Holy Brain: Activating Integrative Processes in Your Nervous System...Rick Hanson
How you can use your mind to reshape your brain for the better, plus three specific ways to promote integrative processes in your brain.
More resources, freely offered at http://www.rickhanson.net
Not-Self in the Brain: Insights from Neuroscience about Not Taking Life Perso...Rick Hanson
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
More resources, freely offered at http://www.rickhanson.net
New science is showing how mental activity sculpts neural structure. Using the power of self-directed neuroplasticity, you can target, stimulate, and thus gradually strengthen the neural substrates of well-being.
More resources are freely offered at http://www.rickhanson.net.
Buddha's Brain: Natural Enlightenment and Unshakable Peace - Rick Hanson, PhDRick Hanson
Combining the power of the latest brain science with the wisdom of contemplative practice, this workshop will present practical methods for centering your brain in its natural state of gladness, love, and peace. In particular, you'll learn brain-savvy ways to reduce anxiety and irritability, feel stronger and safer, and clear old pain.
More resources are freely offered at http://www.rickhanson.net.
The biological evolution of awareness and the apparent self; what neuroscience tells us about the distributed and endlessly variable neural nature of the apparent self; the stress, suffering, and interpersonal difficulties that come from “excesses of self”; the importance of healthy self-compassion and self-advocacy; how to heal injuries to self-worth; methods for taking things less personally, relaxing possessiveness, and feeling more at one with all things.
More resources, freely offered at http://www.rickhanson.net
Buddha's Brain: The Practical Neuroscience of Inner Peace - Rick Hanson, PhDRick Hanson
Integrate the latest brain science research with the ancient wisdom of contemplative practice. Discover practical methods for improving mindfulness and concentration, calming the heart, weaving positive experiences into your brain and your self, and then bringing these new strengths into your relationships with both kindness and assertiveness.
More resources are freely offered at http://www.rickhanson.net.
The Not-Craving Brain: From Greed, Hated and Heartache to Contentment, Peace ...Rick Hanson
An integrated contemplative neuroscience model that can be used in healthy ways, fulfilled and even transcended.
More resources, freely offered at http://www.rickhanson.net
Whose Brain Is It, Anyway? Part I - Rick Hanson, PhDRick Hanson
Talk given at Hampton Boys School, London, England.
* How your brain works
* Why that matters
* What you can do about it
More resources, freely offered at http://www.rickhanson.net
The Neurology of Awakening - Rick Hanson, PhDRick Hanson
Using the New Brain Research to Steady Your Mind.
Introduction to the neuroscience of mindfulness and meditation; brain-wise methods for steadying the mind, quieting it, bringing it to singleness, and concentrating it; an exploration of what could be happening in the brain during the non-ordinary states of consciousness known as samadhis or jhanas.
More resources are freely offered at http://www.rickhanson.net.
The Neurodharma of Love and Power - Rick Hanson - Openground, AustraliaRick Hanson
Practical Tools for Empathy, Kindness and Assertiveness.
On the whole, we experience our greatest joys and sorrows in our relationships. Supported by both Buddhism and Western psychology, the keys to healthy relationships include empathy, compassion, and kindness. These states of mind are based on underlying states of your brain. The emerging integration of modern neuroscience and ancient contemplative wisdom offers increasingly skillful means for activating those brain states – and thus for cultivating an open and caring heart, and more fulfilling relationships.
Definitions of ecstasy, consequences of modern ecstasy deprivation, connection between ecstasy and wisdom, introduction to a spiritual practice based on ancient human art which balances our brain hemispheres, quickens our neurology, releases endorphins, expands imagination and creativity and integrates the bodymind. Good medicine for our modern malaise.
Empathy is the capacity to understand or feel what another person is experiencing from within their frame of reference, that is, the capacity to place oneself in another's position
Slides from Mahasraddha's final talk in the current series, 'Buddhism, Science, Philosophy, and Consciousness'. Given at the Manchester Buddhist Centre on Monday 23rd April 2007.
How the brain’s “negativity bias” makes clients overestimate threats, underestimate opportunities, and underestimate inner and outer resources, leading to anxiety, anger, depression, and conflicts with others – and how to help clients overcome that bias, see the good facts about the others, the world, and themselves, and build resilience for happiness, healthy relationships, and occupational success.
More resources, freely offered at http://www.rickhanson.net
An overview of the positive role of anxiety, and how the work of modern European philosophers can inform a unique approach to helping people face up to, and therefore work through, their fear of fear
It's best to avoid anxiety, or is it? In this presentation, originally given in September 2010 at the Vingsted conference centre in Denmark, Professor Emmy van Deurzen, from the New School of Psychotherapy and Counselling, draws on a philosophical tradition and her own experience as a psychotherapist, to show when anxiety can be a guide to what needs to be fixed in one's life to reach greater wellbeing.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
The Loving Brain - Healing and Treating Trauma, Addictions and Related Disorders Conference, Vancouver, Canada
1. The Loving Brain
Healing and Treating Trauma, Addictions, and Related Disorders
December 2, 2011
Rick Hanson, Ph.D.
The Wellspring Institute for Neuroscience and Contemplative Wisdom
www.WiseBrain.org www.RickHanson.net
drrh@comcast.net
2. Topics
Your loving nature
Two wolves in the heart
On your own side
Empathy
Compassion and lovingkindness
4. Nerve cells form complete circuits that carry and
transform information.
Electrical signaling represents the language of mind.
All animals have some form of mental life that
reflects the architecture of their nervous system.
Eric R. Kandel, 2006
4
5.
6. All sentient beings developed through natural
selection in such a way that pleasant
sensations serve as their guide, and
especially the pleasure derived from
sociability and from loving our families.
Charles Darwin
7.
8.
9. The Social Brain
Social capabilities have been a primary driver of brain evolution.
Reptiles and fish avoid and approach. Mammals and birds
attach as well - especially primates and humans.
Mammals and birds have bigger brains than reptiles and fish.
The more social the primate species, the bigger the cortex.
Since the first hominids began making tools ~ 2.5 million years
ago, the brain has roughly tripled in size, much of its build-out
devoted to social functions (e.g., cooperative planning, empathy,
language). The growing brain needed a longer childhood, which
required greater pair bonding and band cohesion.
10.
11.
12.
13. Oxytocin
It promotes bonding between parents and children -
and between mates and friends, keeping kids alive
In women, it triggers the let-down reflex in nursing,
and tend-and-befriend behaviors during stress.
In both sexes, it dampens the stress response; it
feels pleasurable, relaxed, a “rightness.”
It is stimulated by:
Physical contact (especially skin to skin)
Moving together harmoniously (e.g., dancing)
Warm feelings of rapport or love; devotion
Imagination of these
Nipple stimulation
Orgasm
19. Orgasm in a Woman’s Brain
New Scientist, 5/11/11, study by Barry Kamisaruk, et al. [red = activation; A = PFC; B = ACC]
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31. In the cherry blossom’s shade
there is no thing
as a stranger
Issa
32.
33. If there is anything I have learned about [people], it is that
there is a deeper spirit of altruism than is ever evident.
Just as the rivers we see are minor compared to the
underground streams, so, too, the idealism that is visible is
minor compared to what people carry in their hearts
unreleased or scarcely released.
(Hu)mankind is waiting and longing for those who can
accomplish the task of untying what is knotted, and
bringing these underground waters to the surface.
Albert Schweitzer
39. Us and Them
Core evolutionary strategy: within-group cooperation, and
between-group aggression.
Both capacities and tendencies are hard-wired into our brains,
ready for activation. And there is individual variation.
Our biological nature is much more inclined toward cooperative
sociability than toward aggression and indifference or cruelty.
We are just very reactive to social distinctions and threats.
That reactivity is intensified and often exploited by economic,
cultural, and religious factors.
Two wolves in your heart:
Love sees a vast circle in which all beings are “us.”
Hate sees a small circle of “us,” even only the self.
Which one will you feed?
40. In between-family fights, the baboon’s ‘I’
expands to include all of her close kin;
in within-family fights,
it contracts to include only herself.
This explanation serves for baboons
as much as for the Montagues and Capulets.
Dorothy Cheney and Robert Seyfarth
41. Pain network: Dorsal anterior cingulate cortex (dACC), insula (Ins), somatosensory cortex (SSC), thalamus
(Thal), and periaqueductal gray (PAG).
Reward network: Ventral tegmental area (VTA), ventral striatum (VS), ventromedial prefrontal cortex (VMPFC),
and amygdala (Amyg).
K. Sutliff, in Lieberman & Eisenberger, 2009, Science, 323:890-891
43. Self-Compassion
Compassion is the wish that a being not suffer, combined with
sympathetic concern. Self-compassion simply applies that to
oneself. It is not self-pity, complaining, or wallowing in pain.
Studies show that self-compassion buffers stress and increases
resilience and self-worth.
But self-compassion is hard for many people, due to feelings of
unworthiness, self-criticism, or “internalized oppression.” To
encourage the neural substrates of self-compassion:
Get the sense of being cared about by someone else.
Bring to mind someone you naturally feel compassion for
Sink into the experience of compassion in your body
Then shift the compassion to yourself, perhaps with phrases like:
“May I not suffer. May the pain of this moment pass.”
44. “Anthem”
Ring the bells that still can ring
Forget your perfect offering
There is a crack in everything
That’s how the light gets in
That’s how the light gets in
Leonard Cohen
45. If one going down into a river,
swollen and swiftly flowing,
is carried away by the current --
how can one help others across?
The Buddha
46. The good life, as I conceive it, is a happy life.
I do not mean that if you are good you will be happy;
I mean that if you are happy you will be good.
Bertrand Russell
48. What Is Empathy?
It is sensing, feeling, and understanding how it is for
the other person. In effect, you simulate his or her
inner world.
It involves (sometimes subtly) all of these elements:
Bodily resonance
Emotional attunement
Conceptual understanding
Empathy is usually communicated, often tacitly.
We can give empathy, we can receive it, and we can
ask for it.
49. If we could read the secret history
of our enemies,
we should find in each [person's] life
sorrow and suffering enough
to disarm any hostility.
Henry Wadsworth Longfellow
50. Neural Substrates of Empathy
Three simulating systems:
Actions: “mirror” systems; temporal-parietal
Feelings: resonating emotionally; insula
Thoughts: “theory of mind”; prefrontal cortex
These systems interact with each other through
association and active inquiry.
They produce an automatic, continual re-creation of
aspects of others’ experience.
51. Empathy Skills
Pay attention.
Be open.
Read emotion in face and eyes.
Sense beneath the surface.
Drop aversion (judgments, distaste, fear, anger, withdrawal).
Investigate actively.
Express empathic understanding:
Reflect the content
Resonate with the tone and implicit material
Questions are fine
Offer respect and wise speech throughout
52. Reflections about Empathy
You’re more likely to get empathy if you’re:
Open, present
Honest, real, authentic
Reasonably clear
Responsible for your own experience
Taking it in when you feel felt
Empathy can be negotiated:
Name it as a topic in the relationship
Follow NVC format: “When X happens, I feel Y,
because I need Z. So I request ______ .”
Stay with it.
55. The Wisdom of Connection
A human being is a part of a whole, called by us“universe,” a
part limited in time and space. He experiences himself, his
thoughts and feelings as something separated from the
rest... a kind of optical delusion of his consciousness.
This delusion is a kind of prison for us, restricting us to our
personal desires and to affection for a few persons nearest
to us.
Our task must be to free ourselves from this prison by
widening our circle of compassion to embrace all living
creatures and the whole of nature in its beauty.
Albert Einstein
56. Lovingkindness Practice
Types of wishes
Safety
Health
Happiness
Ease
Types of beings
Self
Benefactor
Friend
Neutral
Difficult
Continually “omitting none” in all directions
57.
58. So that all cubs are our own . . .
All beings are our clan . . .
All life, our relatives . . .
The whole earth, our home . . .
59. Where to Find Rick Hanson Online
http://www.youtube.com/BuddhasBrain
http://www.facebook.com/BuddhasBrain
w
www.RickHanson.net
www.WiseBrain.org 59