As PCI Syllabus

1. HERBAL DRUG INDUSTRY
S.Selvadurai.,M.Pharm.,MBA.,
Associate Professor
Department of Pharmacognosy

4. Worldwide the herbal industry is
picking up at a fast pace.
Herbs and botanicals now appear in
more products and have more medicinal
applications than ever before.
India is blessed with diverse agro-
climatic conditions and is a major source
for a wide variety of medicinal plants.
But the production potential is largely
underexploited.

5. Pharmaceuticals, nutraceuticals,
food and cosmetic industries are
the major buyers of herbal
products.
 Herbal products are in demand
in the form of standardized plant
extracts or botanical ingredients or
semi-finished products.

6. Proportion of manufacturing unites
of different systems
Ayurveda
85%
Unani
4%
siddha
4%
homeopathy
7%

7. • No Side Effects
Herbal
Supplement
• Greater Efficacy
• Acceptance as functional food
Exhibit Robust
Growth
• Rise in Consumer confidence
• Preventive health 7 alternative
medicine regimens
Major factors
aiding market
growth
Present Scope & Future Prospects

8. Leads to preference for
alternative medicine &
dietary supplements
Escalating prices tighter
budgets high healthcare
lifestyle costs
Economical
healthier Safer
option

9. Major Problems for Indian Herbal Industry
Presence of differing regulatory requirements and the limited market
in foreign countries are the major hindrances for exporting.
Standardization and quality control of raw materials and herbal
formulations emerged as the major challenge for Indian herbal drug
manufacturing firms as availability of marker compound is becoming
difficult.
Poor Implementation of drugs and Cosmetics Act,1940 is considered
as major hindrance for the Indian herbal drug industry
Non –availability of sufficient regulatory guidelines to control herbal drugs. In
case available guidelines are not implemented properly good manufacturing
practice, good agricultural & Collection practice.

10. Herbal Drug Industries in India
S.No Name of Industry
Year of
Establishment
Location
01 Baidyanath Ayurvedic Bhavan Ltd. 1917 Kolkata
02 Dabur India Ltd. 1884 Ghaziabad
03 Zandu 1910 Mumbai
04 Charak Pharma Pvy.Ltd. 1946 Mumbai
05 Hamdard laboratories 1906 Delhi
06 Patanjali Ayurved 2006 Haridwar
07 Shri Shri Ayurved 2003 Bangalore
08 Sandu Pharmaceutical Ltd 1899 Mumbai
09 Shri Dhutpapeshwer Ltd 1872 Mumbai
10 Himalaya Drug Company 1930 Bangalore
11 Vicco Laboratories 1952 Mumbai
12 Aarya vaidya Shala 1902 Kottakal, Kerala

11. Brief Account of Plant
Based industries &
Institutions involved in
Work on Medicinal &
aromatic Plants in India

13. On 9th Nov-2014, The ministry of AYUSH was
formed for optimal development & Propagation of
AYUSH systems of health care.
Earlier the Dept of Indian System of Medicine &
Homeopathy(ISM&H) which was created in Mar-
1995 was renamed as
Department of Ayurveda
Yoga & Naturopathy
Unani
Siddha and
Homoeopathy ( AYUSH) in Nov-2003

14. In India there are two Statutory
councils like
Central Council for Indian Medicine (CCIM) &
Central Council for Homoeopathy (CCH).
Two Laboratories namely
Pharmacopoeial Laboratory for Indian
Medicine(PLIM) &
Homoeopathy Pharmacopoeia
Laboratory(HPL)

15. Eight National Institutes Namely
01 • National Institute of Homoeopathy(NIH)
02 • National Institute of Ayurveda(NIA)
03 • National Institute of Unani Medicine(NIUM)
04 • National Institute of Naturopathy(NIN)
05 • National Institute of Sidda(NIS)
06
• Institute of post –graduate Training and
Research in Ayurveda(IPGTRA)
07 • Rashtriya Ayurveda vidyapeeth(RAV)
08 • Moraji Desai national institute of yoga(MDNIY)
& More than 450 Colleges Like Ayu-240, U-39, S-07, H-185

16. Botanical Ethanobotanical
Phytochemical
pharmacological
Pharmacognostical
PreclinicalClinical
Formulation
Toxicity studies
Plant Based Research is Carried Out Mainly in Area Like

17. •Role of CSIR
•Role of Indian Council
of Medical Research
(ICMR)
•Role of NMPB in India

18. INSTITUTES UNDER AYUSH
• 1. National Institute of Ayurveda (NIA), Jaipur
• 2. National Institute of Homeopathy (NIH), Kolkata
• 3. National Institute of Unani Medicine (NIUM), Bengaluru
• 4. National Institute of Siddha (NIS), Chennai
• 5. National institute of Naturopathy (NIN), Pune
• 6. Morarji Desai National Institute of Yoga (MDNIY), New
Delhi
• 7. Institute of Post Graduate Teaching & Research in Ayurveda
(IPGTRA), Jamnagar, Gujarat
• 8. Rashtriya Ayurved Vidyapeeth (RAV), New Delhi
• 9. All India Institute of Ayurveda (AIIA), New Delhi
• 10.North Eastern Institute of Ayurveda & Homoeopathy
(NEIAH), Shillong
• 11.North Eastern Institute of Folk Medicine (NEIFM), Pasighat

19. Some Important Research Institute
in India Related to Herbal Drugs
Central Drug Research
Institute, (CDRI, Lucknow)
www.cdriindia.org/
Drug discovery to development,
synthetic/natural product
chemistry, combinatorial
chemical synthesis, molecular
modelling, HTS, structural
biology, broad-based biological
screening, Pharmacology,
Pharmaco-kinetics, toxicology
phase I clinical studies, chemical
& fermentation technology,
quality control and
standardization,
proteomics, medicinal chemistry,
molecular and cell biology,
phytochemicals/ Herbal Drugs/
nutraceuticals research.
Lab/Instt. Core Competence

20. Indian Institute
of Chemical
Biology (IICB,
Kolkata)
www.iicb.res.in
Synthetic/natural products/
medicinal chemistry,
Infectious Diseases, cellular
physiology, Drug Designing,
molecular modelling,
molecular biology,
Biotechnology, cell signals
for oncogene expression
and metabolic diseases,
immunology, Human
Genetics, genomics,
proteomics, bioinformatics,
Pharmacology,phytochemica
ls / nutraceuticals.

21. Indian Institute of
Chemical Technology
(IICT, Hyderabad)
www.iictindia.org/
Synthetic and natural
product chemistry,
chemical/ process
engineering, combinatorial/
medical Chemistry,
asymmetric synthesis for
chiral Drugs, custom
synthesis, computer-aided
modelling and drug design,
glyco-therapeutics, peptides
and peptido-mimetics,
enzyme mimics (drug
delivery
systems), Pharmacology,
pre-clinical toxicity
pharmacokinetics,
toxicology, phytochemicals/
Herbal Drugs/

22. Indian institute of
Microbial
Technology
(IMT, Chandigarh)
http://www.imtech.
res.in/
Molecular and cell
biology, microbial
genetics, immunology,
structural biology,
protein engineering,
fermentation
technology, culture type
depository, microbial
gene bank,
bioinformatics,
proteomics, molecular
and cell biology.

23. Institute of Genomics
and Integrative
Biology
(IGIB, Delhi)
www.igib.res.in/
Genomics and molecular
medicine, Predictive
Medicine, genome
informatics (in-silico
biology), bio-informatics,
pathway modelling,
proteomics structural
biology, comparative
genomics and gene
expression, Immunology
and Molecular Genetics of
Respiratory Disorders
including Allergy, nucleic
acids and peptides,
Bioactive molecules of
medicinal importance

24. Indian Institute of
Integrative Medicine
(IIIM, Jammu)
http://www.rrljammu.or
g/
Agrotechnology, synthetic
(chiral) and natural product
chemistry, herbal drugs,
select biological screening,
bioprospecting, microbial
biodiversity for industrially
useful enzymes, genetic
fingerprinting, identification/
authentification of medicinal
plants, fermentation
technology, quality control
and standardization of herbal
drugs, establishment of
medicinal plants gene bank,
bioinformatics,
pharmacology,
phytochemicals/ herbal
drugs/ nutraceuticals
research.

25. Central Institute of
Medicinal and
Aromatic
Plants (CIMAP,
Lucknow)
CIMAP, Lucknow)
Agrotechnology of
economically important
herbs, process
technology for
phytochemicals, herbal
drugs, nutraceuticals,
genetic fingerprinting of
plants/ herbs, plant
bioinformatics, genetic
improvement,
bioprospecting,
molecular and cell
biology, quality control
and formulation.

26. Centre for Cellular
and Molecular
Biology,
(CCMB, Hyderabad)
www.ccmb.res.in/
Advanced molecular and
cell biology,
Biotechnology, Sperm-
associated
Proteins/Fertility
Potential of Sperm,
DNA-Fingerprinting,
signal transduction, Eye
Diseases, Hepatitis
Vaccine, Microbial
Genetics,
transgenics, Antimicrob
ial Proteins, genomics,
proteomics molecular
and cell biology.

27. National Chemical
Laboratory (NCL,
Pune)
www.ncl-india.org/
Synthetic chemistry,
tissue culture,
biotechnology, industrial
microbiology,
nanoparticle technology,
smart polymer gels,
chemical/ process
engineering, bioprocess/
enzyme/ fermentation
technology,
combinatorial chemistry,
medicinal chemistry,
quality control and
formulation.

28. Institute of Himalayan
Bioresource
Technology (IHBT,
Palampur)
www.ihbt.res.in
Identification, collection,
isolation and
characterization of plants
and microbes chemical and
molecular characterization
of bioactive, genomics,
tissue culture,
agrotechnology of
medicinal plants,
phytochemicals/ herbal
drugs/ nutraceuticals
research, and chemical/
process engineering.

29. Industrial Toxicology
Research Centre
(ITRC, Lucknow)
www.itrcindia.org/
In vitro test systems for bio-
evaluation/ identification of
molecules or neurological
disorders and antioxidant
activity, complete toxicity
evaluation in small animals;
identification and action
mode of hazardous
toxicants/ pollutants,
diagnostics for toxicants/
pollutants; safety
evaluation/ preventive
measures for
environmental/ industrial
hazards, and quality
assessment of drinking
water.

30. National Botanical
Research Institute
(NBRI, Lucknow)
www.nbri-lko.org/
Pharmacognosy,
ethnopharmacology,
herbal drugs
(authentification,
standardization,
characterization),
nutraceuticals
agrotechnology of
medicinal plants, plant
improvement of
economically important
plants, proteomics,
transgenics, molecular
and cell biology, quality
control and formulation

31. Central Salt &
Marine Chemicals
Research Institute
(CSMCRI,
Bhavnagar)
Bioactive from plants,
cultivation of desert
economic plants and
their value addition, sea
weed cultivation,
phycocolloids and
marine microbes,
biotechnology, synthetic
chemistry and drug
intermediates
desalination water
treatment technology
for pure water for
drinking, low sodium
and plant/ herbal salt.

32. North-East Institute of
Science & Technology
(NEIST, Jorhat)
www.rrljorhat.res.in/
Bioactives from plants, drugs
intermediates, isolation and
characterization of active
molecules and analytical services.
National Institute of
Oceanography (NIO, Goa)
www.nio.org/
Collection and identification of
marine flora and fauna, biological
Screening (antimicrobial,
anticancer, oxytocic, anti-
inflammatory, anti-fouling
cytotoxic,
antimalarial, antiosteoporotic
antiviral, immunomodulatory) and
marine natural product chemistry
for the identification and
structure elucidation of active
molecules.

33. National Institute
of
Interdisciplinary
Science &
Technology
(NIIST,
Trivandrum)
w3rrlt.csir.res.in/
Synthesis of drugs/
drug intermediates,
natural products
isolation, biological
screening, chemical
finger printing,
herbal drugs,
nutraceuticals,
bioprocess/ enzyme
technology and
phytochemicals

34. Central Food
Technological Research
Institute
(CFTRI, Mysore)
www.cftri.com/
Nutraceuticals, health-
promoting effects of spices
herbs/ food (antioxidants,
digestion-stimulants, anti-
inflammatory), traditional
remedies, food-safety/
nutritional toxicology, nodal
codex food laboratory,
animal and plant cell
culture, PCR probes and
biosensors,
phytochemicals/
nutraceuticals research,
quality control &
formulation, toxicology and
bioprocess/ enzyme/
fermentation technology