Hemoglobin is a protein present in the red blood cells. The red color pigmentation of the blood is because of hemoglobin. Hemoglobin is the primary oxygen-carrying protein that circulates throughout the blood.
This document discusses thalassemia, an inherited blood disorder characterized by reduced hemoglobin. There are two main types: alpha thalassemia affects alpha globin gene production, while beta thalassemia affects beta globin genes. Beta thalassemia includes three severities - minor, intermedia, and major ("Cooley's anemia"). Thalassemia is caused by mutations in genes responsible for hemoglobin production, leading to anemia. Management includes frequent blood transfusions, stem cell transplants, folic acid supplements, and monitoring for infections.
Polycythemia is a condition characterized by an abnormal increase in red blood cells. It can be primary, caused by bone marrow abnormalities, or secondary, caused by factors like smoking or lung diseases that result in hypoxia. Symptoms include headache, dizziness, and skin redness or itching. Diagnosis involves blood tests showing elevated red blood cell counts. Treatment may include phlebotomy to reduce blood volume, medications to suppress blood cell production, and lifestyle changes like exercise and avoiding tobacco. Nursing care focuses on monitoring for blood clots, managing pain and nutrition, and providing education.
Due to factors such as genetics, smoking, and living at high altitudes, polycythemia causes an increased number of red blood cells which leads to elevated levels of hemoglobin, hematocrit, and red blood cell count. Symptoms include headache, dizziness, and skin itching. Diagnosis involves blood tests and bone marrow tests. Treatment includes phlebotomy to reduce blood volume, medications to decrease blood cell production, and lifestyle changes like exercise and avoiding tobacco. Nursing care focuses on monitoring for blood clots, administering treatments, providing education, and addressing pain and nutrition needs.
Pallor is a pale skin color caused by reduced oxyhemoglobin levels. It can be caused by anemia, leukemia, heart disease, shock, endocrine disorders, and more. Anemia itself is a reduction in red blood cells, hemoglobin, or red blood cell volume. The most common type is iron deficiency anemia from inadequate iron intake or absorption. Other types include megaloblastic anemia from B12 or folate deficiency, hemolytic anemia from red blood cell membrane issues or immune/non-immune causes, aplastic anemia from bone marrow failure, and anemia of chronic disease seen in infections, inflammation, or cancers.
Anemia is a condition defined by a decrease in red blood cells or hemoglobin in the blood, resulting in paleness and fatigue. This lowers the blood's ability to carry oxygen throughout the body. There are three main types of anemia caused by blood loss, decreased red blood cell production, or increased red blood cell breakdown. Symptoms include weakness, shortness of breath, and pale skin. Anemia is diagnosed through a complete blood count and microscopic examination of a blood smear. Causes include impaired red blood cell production, increased red blood cell destruction, blood loss, or fluid overload. Homeopathic treatments for anemia are individualized but may include remedies like Cinchona for anemia due to blood loss
Thalassemia is an inherited blood disorder caused by variants or missing genes that affect hemoglobin production. This results in reduced red blood cells and mild to severe anemia. There are two main types - alpha and beta thalassemia. Symptoms range from none in minor cases to severe anemia requiring transfusions in major cases. Investigations include blood tests to check hemoglobin levels, red blood cell size and count, and hemoglobin electrophoresis to confirm the diagnosis. Management focuses on blood transfusions and iron chelation therapy to prevent organ damage from excess iron.
This document discusses polycythemia, a disease characterized by an increased number of red blood cells. It describes three main types of polycythemia: absolute polycythemia, which is caused by overproduction of red blood cells in the bone marrow; primary polycythemia, where the levels of white blood cells and platelets are also increased; and relative polycythemia, which results from a decreased blood plasma volume. The document lists potential causes, symptoms, diagnostic tests and treatments to lower the number of red blood cells in cases of polycythemia.
This document summarizes the different types of anemia. It discusses decreased red blood cell production due to nutritional deficiencies like iron deficiency or vitamin B12/folic acid deficiency which leads to megaloblastic anemia. It also discusses decreased red blood cell survival due to hereditary or acquired hemolytic anemias. The types covered include iron deficiency anemia, megaloblastic anemia, aplastic anemia, sickle cell anemia, thalassemia, hereditary spherocytosis, glucose-6-phosphate dehydrogenase deficiency, autoimmune hemolytic anemia, and post-hemorrhagic anemia. Causes, pathophysiology, clinical features and management are described for each type.
This document discusses thalassemia, an inherited blood disorder characterized by reduced hemoglobin. There are two main types: alpha thalassemia affects alpha globin gene production, while beta thalassemia affects beta globin genes. Beta thalassemia includes three severities - minor, intermedia, and major ("Cooley's anemia"). Thalassemia is caused by mutations in genes responsible for hemoglobin production, leading to anemia. Management includes frequent blood transfusions, stem cell transplants, folic acid supplements, and monitoring for infections.
Polycythemia is a condition characterized by an abnormal increase in red blood cells. It can be primary, caused by bone marrow abnormalities, or secondary, caused by factors like smoking or lung diseases that result in hypoxia. Symptoms include headache, dizziness, and skin redness or itching. Diagnosis involves blood tests showing elevated red blood cell counts. Treatment may include phlebotomy to reduce blood volume, medications to suppress blood cell production, and lifestyle changes like exercise and avoiding tobacco. Nursing care focuses on monitoring for blood clots, managing pain and nutrition, and providing education.
Due to factors such as genetics, smoking, and living at high altitudes, polycythemia causes an increased number of red blood cells which leads to elevated levels of hemoglobin, hematocrit, and red blood cell count. Symptoms include headache, dizziness, and skin itching. Diagnosis involves blood tests and bone marrow tests. Treatment includes phlebotomy to reduce blood volume, medications to decrease blood cell production, and lifestyle changes like exercise and avoiding tobacco. Nursing care focuses on monitoring for blood clots, administering treatments, providing education, and addressing pain and nutrition needs.
Pallor is a pale skin color caused by reduced oxyhemoglobin levels. It can be caused by anemia, leukemia, heart disease, shock, endocrine disorders, and more. Anemia itself is a reduction in red blood cells, hemoglobin, or red blood cell volume. The most common type is iron deficiency anemia from inadequate iron intake or absorption. Other types include megaloblastic anemia from B12 or folate deficiency, hemolytic anemia from red blood cell membrane issues or immune/non-immune causes, aplastic anemia from bone marrow failure, and anemia of chronic disease seen in infections, inflammation, or cancers.
Anemia is a condition defined by a decrease in red blood cells or hemoglobin in the blood, resulting in paleness and fatigue. This lowers the blood's ability to carry oxygen throughout the body. There are three main types of anemia caused by blood loss, decreased red blood cell production, or increased red blood cell breakdown. Symptoms include weakness, shortness of breath, and pale skin. Anemia is diagnosed through a complete blood count and microscopic examination of a blood smear. Causes include impaired red blood cell production, increased red blood cell destruction, blood loss, or fluid overload. Homeopathic treatments for anemia are individualized but may include remedies like Cinchona for anemia due to blood loss
Thalassemia is an inherited blood disorder caused by variants or missing genes that affect hemoglobin production. This results in reduced red blood cells and mild to severe anemia. There are two main types - alpha and beta thalassemia. Symptoms range from none in minor cases to severe anemia requiring transfusions in major cases. Investigations include blood tests to check hemoglobin levels, red blood cell size and count, and hemoglobin electrophoresis to confirm the diagnosis. Management focuses on blood transfusions and iron chelation therapy to prevent organ damage from excess iron.
This document discusses polycythemia, a disease characterized by an increased number of red blood cells. It describes three main types of polycythemia: absolute polycythemia, which is caused by overproduction of red blood cells in the bone marrow; primary polycythemia, where the levels of white blood cells and platelets are also increased; and relative polycythemia, which results from a decreased blood plasma volume. The document lists potential causes, symptoms, diagnostic tests and treatments to lower the number of red blood cells in cases of polycythemia.
This document summarizes the different types of anemia. It discusses decreased red blood cell production due to nutritional deficiencies like iron deficiency or vitamin B12/folic acid deficiency which leads to megaloblastic anemia. It also discusses decreased red blood cell survival due to hereditary or acquired hemolytic anemias. The types covered include iron deficiency anemia, megaloblastic anemia, aplastic anemia, sickle cell anemia, thalassemia, hereditary spherocytosis, glucose-6-phosphate dehydrogenase deficiency, autoimmune hemolytic anemia, and post-hemorrhagic anemia. Causes, pathophysiology, clinical features and management are described for each type.
Polycythemia is a blood disorder characterized by an increased red blood cell count. There are two main types: primary polycythemia vera, which is a stem cell cancer caused by a JAK2 mutation; and secondary polycythemia, caused by inappropriate erythropoietin secretion in response to conditions like high altitudes or lung/heart diseases. Polycythemia vera symptoms include headache, itching, fatigue and bleeding risks. Diagnosis involves blood tests showing increased red blood cells, hematocrit, and hemoglobin levels along with a bone marrow biopsy. Treatment focuses on phlebotomy and medications to reduce red blood cell counts.
This document discusses polycythemia, a blood disorder characterized by the overproduction of red blood cells. It defines polycythemia and classifies it as either relative, absolute primary, or absolute secondary. Primary polycythemia, also called polycythemia vera, is caused by a mutation in the JAK2 gene that results in excessive blood cell production. Signs and symptoms include headache, dizziness, itching and red skin. Treatment focuses on phlebotomy to reduce red blood cell counts as well as medications to suppress bone marrow activity.
This document discusses polycythemia, which refers to an increased red blood cell mass. It describes three main types: relative polycythemia caused by decreased plasma volume, secondary polycythemia caused by factors like smoking that stimulate red blood cell production, and polycythemia vera caused by a mutation in the JAK2 protein. Polycythemia vera is a chronic disorder characterized by increased red blood cell, white blood cell and platelet counts. It can cause complications like thrombosis, bleeding, pruritus and splenomegaly. Treatment involves phlebotomy and medications like hydroxyurea to reduce symptoms and risks of complications. Secondary polycythemia is usually caused by lung diseases, tumors
Paroxysmal nocturnal hemolobinurea (PNH) is a rare disease where red blood cells break down earlier than normal due to missing a gene called PIG-A that helps proteins stick to cells and protect them. Without this, red blood cells leak hemoglobin into the blood and urine, especially at night or in the morning. It has symptoms like abdominal pain, dark urine, and easy bruising. Tests like blood counts and urine analysis are used to diagnose. Treatment includes drugs to suppress the immune system and prevent cell breakdown, blood transfusions, iron/folic acid, and possibly bone marrow transplant. Complications can include blood clots, leukemia, or death.
Haemophilia is a bleeding disorder caused by deficiencies in clotting factors VIII or IX. It is inherited through the X chromosome and primarily affects males. Symptoms include prolonged bleeding both internally and externally, especially into joints and muscles. Diagnosis involves measuring factor levels in the blood. Treatment focuses on replacement of the missing clotting factor through medicines or transfusions to prevent or stop bleeding.
This document discusses several endocrine conditions:
1) Addisonian crisis is an adrenal insufficiency emergency characterized by severe symptoms like abdominal pain, vomiting, low blood pressure, and hypoglycemia.
2) Cushing's syndrome and Cushing's disease describe excessive cortisol levels caused by drugs, diseases, or pituitary tumors respectively, leading to symptoms like weight gain and high blood pressure.
3) Hypopituitarism is pituitary hormone deficiency causing sex hormone issues or other symptoms depending on which hormones are deficient.
4) Hyperadrenalism is excessive adrenal hormone production of androgens, corticosteroids or aldosterone causing symptoms like facial hair growth or high blood pressure.
Hemophilia is an inherited bleeding disorder caused by deficient or defective clotting factors. There are three main types - Hemophilia A caused by Factor VIII deficiency, Hemophilia B caused by Factor IX deficiency, and Hemophilia C caused by Factor XI deficiency. Hemophilia A accounts for about 98% of cases and is X-linked recessive inherited. Symptoms range from easy bruising to spontaneous internal bleeding. Diagnosis involves blood tests of clotting factors and family history. Treatment focuses on replacement of missing clotting factors through infusion or preventing bleeding through antifibrinolytic drugs.
seminar on Thalassemia by Dr. habib Dr. mehadi Dr. asadDr. Habibur Rahim
Dr. Habibur Rahman Bhuiyan and other doctors presented a seminar on thalassemia. They discussed a case of an 8-year-old boy with hereditary hemolytic anemia and symptoms of not growing well, pallor, and abdominal distension. The seminar covered the history, epidemiology, genetics, clinical presentations, complications, investigations, and management of different types of thalassemia including beta thalassemia major, beta thalassemia intermedia, HbE beta thalassemia, and alpha thalassemia. Investigations discussed included complete blood count, peripheral blood film, hemoglobin electrophoresis, and radiological imaging.
The document discusses the main causes of anemia, which are blood loss, increased destruction of red blood cells, and decreased production of red blood cells. Blood loss can be acute from overt bleeding or chronic from sources like the gastrointestinal tract or menstruation. Hemolytic anemia is caused by the increased destruction of red blood cells, which can be due to intrinsic defects in red blood cell production or metabolism, or extrinsic factors like infections, medications, autoimmune disorders, or mechanical damage. Decreased production of red blood cells can result from conditions such as aplastic anemia, iron deficiency, sideroblastic anemia, anemia of chronic disease, megaloblastic anemia, or tumors like leukemia.
it is very easy and simplify for MLT Students to understand about different parameters are used in CBC test . This slides give you basic knowledge and information about complete blood count..
Polycythemia vera is a chronic myeloproliferative disorder characterized by an absolute increase in red blood cells, total blood volume, leukocytosis, thrombocytosis, and splenomegaly. It is caused by a clonal proliferation of a hematopoietic stem cell. Symptoms include headaches, visual disturbances, thrombosis, pruritus, and splenomegaly. Diagnosis involves meeting certain criteria including elevated hematocrit. Treatment involves phlebotomy to reduce red blood cell mass and hydroxyurea or interferon-alpha to reduce platelet and white blood cell counts and reduce risk of thrombosis.
This document discusses polycythemia, which refers to an increased red blood cell mass. It is classified as either relative, due to decreased plasma volume, or absolute, which can be primary or secondary. Primary polycythemia, also known as polycythemia vera, results from a stem cell mutation and autonomous red blood cell proliferation. It presents with symptoms like cyanosis, headaches, and thrombosis risk. Diagnosis involves blood tests showing increased red blood cells, hematocrit, and neutrophils. Bone marrow biopsy may show fibrosis. Treatment focuses on phlebotomy and medication to control the excessive red blood cell count.
This document summarizes key components of hematology, including the components of blood, hemoglobin, blood therapies, anemia, blood clotting disorders, and leukemia. It describes that blood contains plasma, buffy coat, and red blood cells, and hemoglobin is the protein that transports oxygen in red blood cells. Therapies include whole blood transfusions, erythropoietin to stimulate red blood cell production, and bone marrow transplants. Anemia can be caused by nutrient deficiencies, blood loss, or bone marrow issues. Specific types include pernicious, aplastic, hemolytic, sickle cell and thalassemia. Blood clotting disorders involve platelet or clotting factor deficiencies. Leuke
A 23-year-old Filipino woman presents with fatigue, lack of appetite, pale skin, dark urine, and abdominal swelling. An initial diagnosis of beta-thalassemia is considered due to her symptoms. Tests would include a blood smear, hemoglobin analysis, and red blood cell count to check for microcytic hypochromic anemia, which are consistent with beta-thalassemia. Beta-thalassemia is a blood disorder where reduced hemoglobin production causes anemia.
Hemolytic anemia results from increased red blood cell destruction that exceeds the bone marrow's ability to produce new cells. It can be classified based on etiology as inherited disorders of hemoglobin structure/deficiency, red blood cell membrane abnormalities, or red blood cell metabolism defects. Acquired causes include immune-mediated hemolytic anemia, mechanical trauma, infections, chemicals/physical agents, and acquired membrane defects like paroxysmal nocturnal hemoglobinuria. Hereditary spherocytosis is the most common membrane defect and causes chronic mild anemia, jaundice, splenomegaly, and bone changes. Paroxysmal nocturnal hemoglobinuria results from a stem cell defect leading to intra
Different blood tests given for bleeding disorders or blood dyscrasiaTickendra Das
The document discusses blood dyscrasias, which are pathological conditions of the blood that usually involve disorders of the cellular elements of blood. Blood dyscrasia can refer to diseases where platelets, white blood cells, or red blood cells are too high or too low. Common blood dyscrasias include diseases that affect platelets like ITP and TTP, diseases that affect clotting factors like hemophilia and von Willebrand's disease, and diseases that affect red blood cells like sickle cell anemia. Tests used to diagnose blood dyscrasias include complete blood count, bleeding time, activated partial thromboplastin time, platelet aggregation test, and prothrombin time.
This document provides an overview of blood dyscrasias (disorders of blood cells). It begins with an introduction to dyscrasia as a concept from ancient Greek medicine meaning "bad mixture." The document then discusses the history of dyscrasias and provides classifications of blood dyscrasias including disorders of red blood cells, white blood cells, hemoglobin, hemostatic mechanisms, and more. Several specific red blood cell disorders are described in detail, including iron deficiency anemia, vitamin B12 deficiency anemia, folic acid deficiency anemia, aplastic anemia, polycythemia, and hereditary spherocytosis. Management and dental considerations are provided for many of these conditions.
Iron deficiency anemia is caused by a lack of iron needed to produce hemoglobin. It develops in stages starting with low iron stores, then reduced red blood cell production, and finally anemia when hemoglobin levels drop below normal. Symptoms include fatigue, paleness, and shortness of breath. It is diagnosed through blood tests measuring iron, ferritin and hemoglobin levels. Treatment focuses on increasing iron intake through an iron-rich diet, vitamin C to aid absorption, and iron supplements to restore normal iron levels in the body.
The hemoglobin test measures the amount of hemoglobin in the blood. Hemoglobin is an iron-containing protein in red blood cells that carries oxygen from the lungs to tissues. The hemoglobin test is done to check for anemia or high red blood cell counts and to monitor treatment response. It involves drawing a blood sample from the arm using a syringe and fine needle. Abnormal hemoglobin levels can indicate various diseases.
Polycythemia is a blood disorder characterized by an increased red blood cell count. There are two main types: primary polycythemia vera, which is a stem cell cancer caused by a JAK2 mutation; and secondary polycythemia, caused by inappropriate erythropoietin secretion in response to conditions like high altitudes or lung/heart diseases. Polycythemia vera symptoms include headache, itching, fatigue and bleeding risks. Diagnosis involves blood tests showing increased red blood cells, hematocrit, and hemoglobin levels along with a bone marrow biopsy. Treatment focuses on phlebotomy and medications to reduce red blood cell counts.
This document discusses polycythemia, a blood disorder characterized by the overproduction of red blood cells. It defines polycythemia and classifies it as either relative, absolute primary, or absolute secondary. Primary polycythemia, also called polycythemia vera, is caused by a mutation in the JAK2 gene that results in excessive blood cell production. Signs and symptoms include headache, dizziness, itching and red skin. Treatment focuses on phlebotomy to reduce red blood cell counts as well as medications to suppress bone marrow activity.
This document discusses polycythemia, which refers to an increased red blood cell mass. It describes three main types: relative polycythemia caused by decreased plasma volume, secondary polycythemia caused by factors like smoking that stimulate red blood cell production, and polycythemia vera caused by a mutation in the JAK2 protein. Polycythemia vera is a chronic disorder characterized by increased red blood cell, white blood cell and platelet counts. It can cause complications like thrombosis, bleeding, pruritus and splenomegaly. Treatment involves phlebotomy and medications like hydroxyurea to reduce symptoms and risks of complications. Secondary polycythemia is usually caused by lung diseases, tumors
Paroxysmal nocturnal hemolobinurea (PNH) is a rare disease where red blood cells break down earlier than normal due to missing a gene called PIG-A that helps proteins stick to cells and protect them. Without this, red blood cells leak hemoglobin into the blood and urine, especially at night or in the morning. It has symptoms like abdominal pain, dark urine, and easy bruising. Tests like blood counts and urine analysis are used to diagnose. Treatment includes drugs to suppress the immune system and prevent cell breakdown, blood transfusions, iron/folic acid, and possibly bone marrow transplant. Complications can include blood clots, leukemia, or death.
Haemophilia is a bleeding disorder caused by deficiencies in clotting factors VIII or IX. It is inherited through the X chromosome and primarily affects males. Symptoms include prolonged bleeding both internally and externally, especially into joints and muscles. Diagnosis involves measuring factor levels in the blood. Treatment focuses on replacement of the missing clotting factor through medicines or transfusions to prevent or stop bleeding.
This document discusses several endocrine conditions:
1) Addisonian crisis is an adrenal insufficiency emergency characterized by severe symptoms like abdominal pain, vomiting, low blood pressure, and hypoglycemia.
2) Cushing's syndrome and Cushing's disease describe excessive cortisol levels caused by drugs, diseases, or pituitary tumors respectively, leading to symptoms like weight gain and high blood pressure.
3) Hypopituitarism is pituitary hormone deficiency causing sex hormone issues or other symptoms depending on which hormones are deficient.
4) Hyperadrenalism is excessive adrenal hormone production of androgens, corticosteroids or aldosterone causing symptoms like facial hair growth or high blood pressure.
Hemophilia is an inherited bleeding disorder caused by deficient or defective clotting factors. There are three main types - Hemophilia A caused by Factor VIII deficiency, Hemophilia B caused by Factor IX deficiency, and Hemophilia C caused by Factor XI deficiency. Hemophilia A accounts for about 98% of cases and is X-linked recessive inherited. Symptoms range from easy bruising to spontaneous internal bleeding. Diagnosis involves blood tests of clotting factors and family history. Treatment focuses on replacement of missing clotting factors through infusion or preventing bleeding through antifibrinolytic drugs.
seminar on Thalassemia by Dr. habib Dr. mehadi Dr. asadDr. Habibur Rahim
Dr. Habibur Rahman Bhuiyan and other doctors presented a seminar on thalassemia. They discussed a case of an 8-year-old boy with hereditary hemolytic anemia and symptoms of not growing well, pallor, and abdominal distension. The seminar covered the history, epidemiology, genetics, clinical presentations, complications, investigations, and management of different types of thalassemia including beta thalassemia major, beta thalassemia intermedia, HbE beta thalassemia, and alpha thalassemia. Investigations discussed included complete blood count, peripheral blood film, hemoglobin electrophoresis, and radiological imaging.
The document discusses the main causes of anemia, which are blood loss, increased destruction of red blood cells, and decreased production of red blood cells. Blood loss can be acute from overt bleeding or chronic from sources like the gastrointestinal tract or menstruation. Hemolytic anemia is caused by the increased destruction of red blood cells, which can be due to intrinsic defects in red blood cell production or metabolism, or extrinsic factors like infections, medications, autoimmune disorders, or mechanical damage. Decreased production of red blood cells can result from conditions such as aplastic anemia, iron deficiency, sideroblastic anemia, anemia of chronic disease, megaloblastic anemia, or tumors like leukemia.
it is very easy and simplify for MLT Students to understand about different parameters are used in CBC test . This slides give you basic knowledge and information about complete blood count..
Polycythemia vera is a chronic myeloproliferative disorder characterized by an absolute increase in red blood cells, total blood volume, leukocytosis, thrombocytosis, and splenomegaly. It is caused by a clonal proliferation of a hematopoietic stem cell. Symptoms include headaches, visual disturbances, thrombosis, pruritus, and splenomegaly. Diagnosis involves meeting certain criteria including elevated hematocrit. Treatment involves phlebotomy to reduce red blood cell mass and hydroxyurea or interferon-alpha to reduce platelet and white blood cell counts and reduce risk of thrombosis.
This document discusses polycythemia, which refers to an increased red blood cell mass. It is classified as either relative, due to decreased plasma volume, or absolute, which can be primary or secondary. Primary polycythemia, also known as polycythemia vera, results from a stem cell mutation and autonomous red blood cell proliferation. It presents with symptoms like cyanosis, headaches, and thrombosis risk. Diagnosis involves blood tests showing increased red blood cells, hematocrit, and neutrophils. Bone marrow biopsy may show fibrosis. Treatment focuses on phlebotomy and medication to control the excessive red blood cell count.
This document summarizes key components of hematology, including the components of blood, hemoglobin, blood therapies, anemia, blood clotting disorders, and leukemia. It describes that blood contains plasma, buffy coat, and red blood cells, and hemoglobin is the protein that transports oxygen in red blood cells. Therapies include whole blood transfusions, erythropoietin to stimulate red blood cell production, and bone marrow transplants. Anemia can be caused by nutrient deficiencies, blood loss, or bone marrow issues. Specific types include pernicious, aplastic, hemolytic, sickle cell and thalassemia. Blood clotting disorders involve platelet or clotting factor deficiencies. Leuke
A 23-year-old Filipino woman presents with fatigue, lack of appetite, pale skin, dark urine, and abdominal swelling. An initial diagnosis of beta-thalassemia is considered due to her symptoms. Tests would include a blood smear, hemoglobin analysis, and red blood cell count to check for microcytic hypochromic anemia, which are consistent with beta-thalassemia. Beta-thalassemia is a blood disorder where reduced hemoglobin production causes anemia.
Hemolytic anemia results from increased red blood cell destruction that exceeds the bone marrow's ability to produce new cells. It can be classified based on etiology as inherited disorders of hemoglobin structure/deficiency, red blood cell membrane abnormalities, or red blood cell metabolism defects. Acquired causes include immune-mediated hemolytic anemia, mechanical trauma, infections, chemicals/physical agents, and acquired membrane defects like paroxysmal nocturnal hemoglobinuria. Hereditary spherocytosis is the most common membrane defect and causes chronic mild anemia, jaundice, splenomegaly, and bone changes. Paroxysmal nocturnal hemoglobinuria results from a stem cell defect leading to intra
Different blood tests given for bleeding disorders or blood dyscrasiaTickendra Das
The document discusses blood dyscrasias, which are pathological conditions of the blood that usually involve disorders of the cellular elements of blood. Blood dyscrasia can refer to diseases where platelets, white blood cells, or red blood cells are too high or too low. Common blood dyscrasias include diseases that affect platelets like ITP and TTP, diseases that affect clotting factors like hemophilia and von Willebrand's disease, and diseases that affect red blood cells like sickle cell anemia. Tests used to diagnose blood dyscrasias include complete blood count, bleeding time, activated partial thromboplastin time, platelet aggregation test, and prothrombin time.
This document provides an overview of blood dyscrasias (disorders of blood cells). It begins with an introduction to dyscrasia as a concept from ancient Greek medicine meaning "bad mixture." The document then discusses the history of dyscrasias and provides classifications of blood dyscrasias including disorders of red blood cells, white blood cells, hemoglobin, hemostatic mechanisms, and more. Several specific red blood cell disorders are described in detail, including iron deficiency anemia, vitamin B12 deficiency anemia, folic acid deficiency anemia, aplastic anemia, polycythemia, and hereditary spherocytosis. Management and dental considerations are provided for many of these conditions.
Iron deficiency anemia is caused by a lack of iron needed to produce hemoglobin. It develops in stages starting with low iron stores, then reduced red blood cell production, and finally anemia when hemoglobin levels drop below normal. Symptoms include fatigue, paleness, and shortness of breath. It is diagnosed through blood tests measuring iron, ferritin and hemoglobin levels. Treatment focuses on increasing iron intake through an iron-rich diet, vitamin C to aid absorption, and iron supplements to restore normal iron levels in the body.
The hemoglobin test measures the amount of hemoglobin in the blood. Hemoglobin is an iron-containing protein in red blood cells that carries oxygen from the lungs to tissues. The hemoglobin test is done to check for anemia or high red blood cell counts and to monitor treatment response. It involves drawing a blood sample from the arm using a syringe and fine needle. Abnormal hemoglobin levels can indicate various diseases.
Polycythemia is a blood disorder where the body produces too many red blood cells. It can be primary, caused by problems in bone marrow production of red blood cells, or secondary, caused by factors like lung or heart diseases that result in low oxygen levels triggering high red blood cell production. Symptoms include feeling tired, shortness of breath, headaches, and itchy skin. Diagnosis involves blood tests showing high red blood cell counts and hematocrit levels. Treatment focuses on phlebotomy to reduce red blood cell counts through blood removal, along with medications in some cases to suppress bone marrow production of red blood cells.
This document discusses anemia, which is a medical condition defined by low red blood cell or hemoglobin levels. It describes how hemoglobin transports oxygen in red blood cells and the normal hemoglobin levels for men and women. Some key causes of anemia include blood loss, issues with erythropoietin production, problems making red blood cells, and red blood cell destruction. Common symptoms are fatigue, paleness, breathlessness and headache. Anemia is evaluated by measuring hemoglobin, hematocrit, red blood cell count and other factors. Types of anemia include iron deficiency, megaloblastic, and hemolytic anemia. Treatment involves addressing the underlying cause through diet, supplements, medication or other procedures.
This document provides information on normal hematological values and various blood disorders including anemia, thalassemia, hemophilia, and leukemia. It then focuses on anemia, discussing types such as iron deficiency, hemolytic, and megaloblastic anemia. Iron deficiency anemia is defined and causes, pathophysiology, diagnostic tests, and management are outlined. Sickle cell anemia and thalassemia are also defined and their causes, inheritance patterns, clinical manifestations, diagnosis, treatment and nursing management are summarized.
Anemia is a major public health problem in India, especially among women and children. It can be caused by iron deficiency, vitamin B12 or folate deficiency, chronic illnesses, parasitic infections, and other factors. Common symptoms include fatigue, weakness, dizziness, and pale skin. Diagnosis involves blood tests to measure hemoglobin, red blood cell count, and other indicators. Treatment depends on the underlying cause but often involves dietary changes and iron supplements taken by mouth or via injection. Public health efforts are needed to prevent anemia through nutrition education, parasite control, and antenatal supplementation programs.
This document defines anemia as a deficiency in red blood cells or hemoglobin that reduces oxygen-carrying capacity in the blood. It notes normal red blood cell counts differ between males and females and lists several risk factors for anemia including poor diet, menstrual periods, pregnancy, and chronic illnesses. The document classifies anemias and discusses symptoms, diagnostic tests, and treatments which include iron supplements, vitamins, medications, and blood transfusions depending on the underlying cause of the anemia.
Anemia is a medical condition where the red blood cell count or hemoglobin levels are lower than normal. It can be caused by blood loss, nutritional deficiencies, or conditions that impair red blood cell production. Common symptoms include fatigue, weakness, and pale skin. Diagnosis involves blood tests to measure red blood cell counts and hemoglobin levels. Treatment depends on the underlying cause but may include iron supplements, vitamin supplements, blood transfusions, or medications. Thalassemia is an inherited blood disorder caused by a genetic defect that impairs hemoglobin production, leading to anemia. There are different types depending on which globin chain is affected. Symptoms range from mild to severe and include fatigue, jaundice, and
This document discusses thalassemia, a group of inherited blood disorders characterized by reduced or absent hemoglobin production. There are three main types: thalassemia minor causes no symptoms; thalassemia major requires lifelong blood transfusions and causes severe anemia symptoms from infancy; thalassemia intermedia causes variable non-transfusion dependent anemia that can worsen during times of stress. Long term complications of thalassemia include anemia, bone and growth problems, iron overload, and organ damage to the liver, heart, and endocrine system. Treatment focuses on blood transfusions, iron chelation therapy, and managing complications.
Heamatological Disorder-WPS Office.pptxSudipta Roy
Iron deficiency anemia is a common type of anemia caused by low iron levels. It develops when iron loss from bleeding or inadequate dietary iron intake exceeds the amount the body absorbs. Symptoms include fatigue, pale skin, shortness of breath, and irregular heartbeat. Diagnosis involves blood tests to measure hemoglobin and iron levels. Treatment focuses on oral iron supplements and improving iron intake through diet.
Iron deficiency anemia is the most common type of anemia globally. It is caused by low iron levels which prevents adequate hemoglobin production. Common symptoms include fatigue, weakness, and pale skin. Treatment involves oral or intravenous iron supplementation to replenish iron stores depending on the severity and underlying cause of the anemia. Oral iron is usually the first line treatment but intravenous iron may be needed if oral iron is not absorbed or anemia does not improve. Both forms can cause side effects but are generally safe and effective ways to treat iron deficiency anemia.
This document provides an overview of hemolytic anemia in children. It defines hemolytic anemia as anemia resulting from increased red blood cell destruction. The document describes the different types of hemolytic anemia including hereditary, immune, and non-immune causes. It outlines the pathophysiology, clinical features, diagnostic approach and management of common forms of hemolytic anemia in children such as hereditary spherocytosis, thalassemia, sickle cell anemia, and G6PD deficiency. Investigations for diagnosis include blood counts, peripheral smear, reticulocyte count, hemoglobin electrophoresis and enzyme or genetic testing depending on etiology.
This document discusses suffixes related to conditions of the endocrine system. The suffix -emia refers to the presence of a substance in the blood and is seen in conditions like anemia, septicemia, and hyperlipidemia. Anemia is a lack of red blood cells, septicemia involves bacteria in the bloodstream, and hyperlipidemia is high cholesterol levels. The suffix -dipsia means thirst and is seen in hypodipsia, meaning low fluid intake, and polydipsia, meaning excessive thirst often from conditions like diabetes.
Hemolytic anemia occurs when the destruction of red blood cells outpaces their production. It can develop intrinsically due to abnormalities in red blood cells, such as in sickle cell anemia or thalassemia. Or it can occur extrinsically due to infection, autoimmune disorders, medications or splenic sequestration of normal red blood cells. Symptoms include pallor, fatigue, jaundice and dark urine. Treatment depends on the underlying cause but may include blood transfusions, medications to suppress the immune system, splenectomy or stem cell transplant.
This document provides information about various types of blood tests, including their purpose and normal ranges. It discusses common blood tests such as complete blood count, lipid profile, liver function tests, electrolytes, troponin, blood glucose, and others. The tests check for conditions like anemia, infections, kidney function, diabetes, and heart disease. Knowing the results of blood tests is important for diagnosing health issues and monitoring treatment effectiveness.
This document provides an overview of anemia, including its definition, classifications, causes, and methods of diagnosis. Anemia is classified based on pathophysiology (increased blood loss, impaired red blood cell production, increased destruction), morphology (microcytic/hypochromic, normocytic/normochromic, macrocytic/normochromic), and function (hypoproliferative, ineffective, hemolytic). Common causes of different types of anemia are outlined. Laboratory tests including red blood cell indices help diagnose the type of anemia and indicate the underlying cause.
Exploring the Benefits of Binaural Hearing: Why Two Hearing Aids Are Better T...Ear Solutions (ESPL)
Binaural hearing using two hearing aids instead of one offers numerous advantages, including improved sound localization, enhanced sound quality, better speech understanding in noise, reduced listening effort, and greater overall satisfaction. By leveraging the brain’s natural ability to process sound from both ears, binaural hearing aids provide a more balanced, clear, and comfortable hearing experience. If you or a loved one is considering hearing aids, consult with a hearing care professional at Ear Solutions hearing aid clinic in Mumbai to explore the benefits of binaural hearing and determine the best solution for your hearing needs. Embracing binaural hearing can lead to a richer, more engaging auditory experience and significantly improve your quality of life.
Gemma Wean- Nutritional solution for Artemiasmuskaan0008
GEMMA Wean is a high end larval co-feeding and weaning diet aimed at Artemia optimisation and is fortified with a high level of proteins and phospholipids. GEMMA Wean provides the early weaned juveniles with dedicated fish nutrition and is an ideal follow on from GEMMA Micro or Artemia.
GEMMA Wean has an optimised nutritional balance and physical quality so that it flows more freely and spreads readily on the water surface. The balance of phospholipid classes to- gether with the production technology based on a low temperature extrusion process improve the physical aspect of the pellets while still retaining the high phospholipid content.
GEMMA Wean is available in 0.1mm, 0.2mm and 0.3mm. There is also a 0.5mm micro-pellet, GEMMA Wean Diamond, which covers the early nursery stage from post-weaning to pre-growing.
Can Allopathy and Homeopathy Be Used Together in India.pdfDharma Homoeopathy
This article explores the potential for combining allopathy and homeopathy in India, examining the benefits, challenges, and the emerging field of integrative medicine.
Let's Talk About It: Breast Cancer (What is Mindset and Does it Really Matter?)bkling
Your mindset is the way you make sense of the world around you. This lens influences the way you think, the way you feel, and how you might behave in certain situations. Let's talk about mindset myths that can get us into trouble and ways to cultivate a mindset to support your cancer survivorship in authentic ways. Let’s Talk About It!
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
MBC Support Group for Black Women – Insights in Genetic Testing.pdfbkling
Christina Spears, breast cancer genetic counselor at the Ohio State University Comprehensive Cancer Center, joined us for the MBC Support Group for Black Women to discuss the importance of genetic testing in communities of color and answer pressing questions.
At Apollo Hospital, Lucknow, U.P., we provide specialized care for children experiencing dehydration and other symptoms. We also offer NICU & PICU Ambulance Facility Services. Consult our expert today for the best pediatric emergency care.
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This particular slides consist of- what is Pneumothorax,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is a summary of Pneumothorax:
Pneumothorax, also known as a collapsed lung, is a condition that occurs when air leaks into the space between the lung and chest wall. This air buildup puts pressure on the lung, preventing it from expanding fully when you breathe. A pneumothorax can cause a complete or partial collapse of the lung.
2024 HIPAA Compliance Training Guide to the Compliance OfficersConference Panel
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Healthy Eating Habits:
Understanding Nutrition Labels: Teaches how to read and interpret food labels, focusing on serving sizes, calorie intake, and nutrients to limit or include.
Tips for Healthy Eating: Offers practical advice such as incorporating a variety of foods, practicing moderation, staying hydrated, and eating mindfully.
Benefits of Regular Exercise:
Physical Benefits: Discusses how exercise aids in weight management, muscle and bone health, cardiovascular health, and flexibility.
Mental Benefits: Explains the psychological advantages, including stress reduction, improved mood, and better sleep.
Tips for Staying Active:
Encourages consistency, variety in exercises, setting realistic goals, and finding enjoyable activities to maintain motivation.
Maintaining a Balanced Lifestyle:
Integrating Nutrition and Exercise: Suggests meal planning and incorporating physical activity into daily routines.
Monitoring Progress: Recommends tracking food intake and exercise, regular health check-ups, and provides tips for achieving balance, such as getting sufficient sleep, managing stress, and staying socially active.
2. Hemoglobin
• It is a protein present in the red
blood cells.
• The red color pigmentation of the
blood is because of hemoglobin.
• Also, called has metalloprotein.
Since it contains co-factor or
supporting element.
• Complete Blood Count (CBC) is
blood test used to test level of
hemoglobin.
3. Normal levels of hemoglobin
Normal levels of hemoglobin ( grams present per
deciliter)
Newborns 17 to 21 gm/dL
One month old 11 to 14 gm/dL
Children 12 to 14 gm/dL
Male 14 to 18 gm/dL
Female 12 to 16 gm/dL
Men above 40 years or above 12.4 to 14.9 gm/dL
Women above 40 years or above 11.7 to 13.8 gm/dL
4. Low Hemoglobin level
• This conditions is also called as “Anemia”.
• Caused by low red blood cells count (RBC)
Reference ranges of Hemoglobin levels
Men < 13gm/100ml
Women < 11.5gm/100ml
6. Low hemoglobin level Symptoms
• Drowsiness
• Headaches
• Shortness of breath
• Pale or yellow skin
• Brittle nails
• Joint pains
• Unable to do physical activities
7. High Hemoglobin levels
• Note people who live at higher
altitudes have this condition.
• Usually seen in chain smokers.
8. Causes of High Hemoglobin levels
• Heart diseases
• Lung disorders
• Polycythemia
• Bone marrow defects
• Liver Diseases like Emphysem
• Certain blood cancers
• Congenital heart diseases
9. High Hemoglobin level Symptoms
• Frequent urination
• Bluish discoloration of hands and legs which is termed as Peripheral
cyanosis
• The limitation of the blood flow to the tissues leads to symptoms
similar to Anemia
10. How to reduce Hemoglobin levels
Blood donation
• Prefer low altitudes
• Increase physical activity
• Quit Smoking
• Sufficient hydration
• Phlebotomy
• Avoid vitamin C and iron-enriched foods
• Avoid multivitamins and iron supplements