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Health & Medicine Drug Delivery
Module Outcomes ,[object Object],[object Object],[object Object],[object Object]
What If? What if you never had to have another needle? Image:  [email_address]
What If? What if you could prevent disease more easily in developing countries? Image:  [email_address]
Did You Know? ,[object Object],[object Object],Image:  [email_address]
What If? What if there was an alternative to needles for delivery of vaccines and drugs like insulin?
What Is A Transdermal Patch? Delivery of drug/vaccine into skin Example of transdermal patch Images: Courtesy Nanotechnology Victoria Ltd, Resin[sistem] Design ,[object Object],[object Object]
Activity 1 Image:  [email_address] Complete the  Vaccination   SWOT Analysis Activity  to compare the strengths and weaknesses of conventional and transdermal methods of vaccination.
How Do Vaccines Work? Image: Sarah Keenihan ,[object Object],[object Object],[object Object],antigen lymphocytes lymph node APC skin
How Do Vaccines Work? Image: © Dorling Kindersley ,[object Object],[object Object]
Animation Watch the  Vaccination  and  Transdermal Patch Animations  to improve your understanding of delivering vaccines and drugs via the skin.
Benefits Of Transdermal Patches Image: Courtesy Nanotechnology Victoria Ltd What are the benefits of transdermal delivery from a medical point of view?
Benefits Of Transdermal Patches Image: Courtesy Nanotechnology Victoria Ltd ,[object Object],[object Object],[object Object],[object Object],Microscopic images of transdermal patch protrusions
Benefits Of Transdermal Patches ,[object Object],[object Object],[object Object]
Benefits Of Transdermal Patches ,[object Object]
Nano-Formulated Vaccines Trigger An Optimal Immune Response Image: Courtesy Nanotechnology Victoria Ltd, based on data from Intersuisse Bioscience, 2006 Data was generated by vaccinating mice with various sized particles, and then counting the number of activated immune cells. Vaccine particle size Immune response (number of activated immune cells per million total cells) 0 30nm 100nm 500nm 1000nm
Advantages Of Transdermal Patches: Summary Image: pruzicka@flcikr ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other Examples Of Transdermal Patches Image: andreas@flickr ,[object Object],[object Object]
Wearable Transdermal Patches Image:  © Leah Heiss,  ,[object Object],[object Object],Insulin-dispensing rings designed by Nanotechnology Victoria ‘Artist in Residence’  Ms Leah Heiss
Activity 2 Perform the  Transdermal Patches Activity  to gain an understanding of the history and development of transdermal patches.
Experiment 1   Transdermal Immunisation Perform the  Modelling Transdermal Immunisation   Experiment  to better visualise this mode of delivering vaccines and drugs.
Designing Better Transdermal Patches Image: © Dorling Kindersley ,[object Object],[object Object],[object Object]
Human Skin Image: alosojos@flickr The skin is the largest and heaviest organ of the body. ,[object Object],[object Object],[object Object],[object Object],[object Object]
What Is Skin Made Of? Image: © Dorling Kindersley ,[object Object],[object Object],pore oil gland hair epidermis dermis subcutaneous layer erector pili muscle hair follicle blood vessels nerve sweat gland
Activity 3 & Experiment 2 Perform the  Structure and Function of Skin Activity  and/or the  Skin Observation Experiment   to learn more about skin.
Function Of Skin: Barrier Image: karlasfotos@flickr ,[object Object],[object Object],[object Object],[object Object],[object Object]
Function Of Skin: Temperature Control Image: aliciayeah@flickr ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Temperature Control: Sweating Image: © Dorling Kindersley ,[object Object],[object Object],[object Object],[object Object],SOLID LIQUID GAS energy absorbed energy released
Temperature Control: Vasodilation Image: linnybinnypix@flickr ,[object Object],[object Object],[object Object]
Temperature Control: Goose Bumps Image: © Dorling Kindersley warm cold ,[object Object],[object Object],[object Object]
Extended Learning Other examples of nanotechnology in medicine.  ,[object Object],[object Object]
What If? What if you could stop the spread of HIV in the developing world? Image:  [email_address] Photo taken outside a school in Zambia, Africa in 2005
HIV Prevention: Viva Gel TM Image:  ©  StarPharma ,[object Object],[object Object],[object Object]
HIV Infection Image:  ©  StarPharma ,[object Object],[object Object],[object Object]
How The Dendrimer Works Image:  ©  StarPharma ,[object Object],[object Object],[object Object]
Tooth Repair: Recaldent Watch video: www. gcamerica.com   ,[object Object],Recaldent was developed in Australia
Summary ,[object Object],[object Object],[object Object]
Revision ,[object Object],[object Object],[object Object],[object Object]
 

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Health & Medicine Module - Drug Delivery

  • 1. Health & Medicine Drug Delivery
  • 2.
  • 3. What If? What if you never had to have another needle? Image: [email_address]
  • 4. What If? What if you could prevent disease more easily in developing countries? Image: [email_address]
  • 5.
  • 6. What If? What if there was an alternative to needles for delivery of vaccines and drugs like insulin?
  • 7.
  • 8. Activity 1 Image: [email_address] Complete the Vaccination SWOT Analysis Activity to compare the strengths and weaknesses of conventional and transdermal methods of vaccination.
  • 9.
  • 10.
  • 11. Animation Watch the Vaccination and Transdermal Patch Animations to improve your understanding of delivering vaccines and drugs via the skin.
  • 12. Benefits Of Transdermal Patches Image: Courtesy Nanotechnology Victoria Ltd What are the benefits of transdermal delivery from a medical point of view?
  • 13.
  • 14.
  • 15.
  • 16. Nano-Formulated Vaccines Trigger An Optimal Immune Response Image: Courtesy Nanotechnology Victoria Ltd, based on data from Intersuisse Bioscience, 2006 Data was generated by vaccinating mice with various sized particles, and then counting the number of activated immune cells. Vaccine particle size Immune response (number of activated immune cells per million total cells) 0 30nm 100nm 500nm 1000nm
  • 17.
  • 18.
  • 19.
  • 20. Activity 2 Perform the Transdermal Patches Activity to gain an understanding of the history and development of transdermal patches.
  • 21. Experiment 1 Transdermal Immunisation Perform the Modelling Transdermal Immunisation Experiment to better visualise this mode of delivering vaccines and drugs.
  • 22.
  • 23.
  • 24.
  • 25. Activity 3 & Experiment 2 Perform the Structure and Function of Skin Activity and/or the Skin Observation Experiment to learn more about skin.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32. What If? What if you could stop the spread of HIV in the developing world? Image: [email_address] Photo taken outside a school in Zambia, Africa in 2005
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.  

Editor's Notes

  1. Drug Delivery - Title Page