This document discusses concepts related to health, disease, and their determinants. It covers: 1) Different historical concepts of health including biomedical, ecological, psycho-social, holistic, and positive health concepts. 2) Determinants of health like biological, behavioral, environmental, socio-economic, and health system factors. 3) The web of causation model which shows how various risk factors can interact and accumulate to result in disease. 4) Concepts of prevention including primary, secondary, and tertiary prevention strategies to reduce disease burden.