This document contains 23 multiple choice questions prepared by Dr. K.L. Deepthi on the topic of novel drug delivery systems. It covers various drug delivery technologies including microballoons, liposomes, implants, transdermal patches, inhalers, and technologies for delivering drugs to specific sites like the eye, colon, and nasal cavity. The questions test understanding of the components, mechanisms, materials, and advantages of different controlled and targeted release drug delivery systems.

1. GPAT BITS
Novel drug delivery systems
2022
PREPARED BY
Dr. K.L.DEEPTHI, M.PHARM PH.D
Associate professor,
DEPARTMENT OF PHARMACEUTICS
Raghu college of pharmacy,
Vishakhapatnam.

2. Q1
MICROBALLOONS ARE:
A. hollow microspheres
B. microspheres with prolonged GRT
C. EUDRGIT containing microspheres
D. all of the above
2
DR K.L.DEEPTHI RCP

3. Q2
2. A non-ionic surfactant based multilamellar or
unilamellar vesicular structure
A. Microspheres
B. Liposome
C. Niosome
D. Nanoparticle
3
DR K.L.DEEPTHI RCP

4. Q3
3. Which of the following is a non- erodible
insert?
A. Ocusert
B. Collagen shield
C. NODS
D. SODI
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DR K.L.DEEPTHI RCP

5. Q4
4. The polymer used in “Lacriset”
A. Hydoxy ethyl cellulose
B. Hydoxy Methyl cellulose
C. Methyl cellulose
D. Hydroxy propyl cellulose
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DR K.L.DEEPTHI RCP

6. Q5
List out abiodegradable polymer
A. Polylactides (PLA)
B. Polyglycolides (PGA)
C. Poly(lactide-co-glycolides) (PLGA)
D. All of the Above
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DR K.L.DEEPTHI RCP

7. Q6
Achievement of zero order is easy for:
A. Matrix Systems
B. Reservoir systems
C. none of the above
D. both a & B
7
DR K.L.DEEPTHI RCP

8. Q7
In diffusion and dissolution controlled systems,
the Release rate is dependent on
A. surface area
B. diffusion coefficient of drug though pore in
coating
C. diffusion path length
D. all of the above
8
DR K.L.DEEPTHI RCP

9. Q8
Materials Used as Retardants in Matrix Tablet
Formulations
A. Polyethylene
B. Polyvinyl acetate
C. Polyvinyl chloride
D. All of the above
9
DR K.L.DEEPTHI RCP

10. Q9
A Polymer used for colonic systems is
A. carboxymethyl cellulose
B. cellulose acetate phthalate
C. gelatin
D. acacia
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11. Q 10
Excipient to increase density of GRDDS is
A. zinc oxide
B. barium sulfate
C.titanium dioxide
D. All of the above
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12. Q 11
One method to prepare liposomes is
A. pan coating
B. filtration
C. ether injection
D. precipitation
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13. Q12
Sodium taurocholate used as penetration
enhancer is
• A. A Surfactant
• B. Fatty acid with surfactant property
• C. Bile salt
• D. All of the above
13
DR K.L.DEEPTHI RCP

14. Q13
The IMPLANT oncogel which is used in
oesophagal cancer contains ------------ polymer
• A. silicon
• B. methacrylate
• C. PLGA-PEG-PLGA
• D. all of the above
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DR K.L.DEEPTHI RCP

15. Q 14
BASIC COMPONENTS OFA TRANSDERMAL
PATCH:
A. polymer matrix
B. backing membrane
C. adhesive
D. all of the above
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16. Q15
Stealth liposomes
A. PEG containing
B. are sterically stabilized
C. only A
D. both A and B
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17. Q16
Which of the following is theory of mucoadhesion
A. Adsorption
B. DISSOUTION
C. ABSORPTION
D.HIXSON
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18. Q17
The metered dose inhalers has the advantage:
A. high reliability and stability
B. high reliability and accurate performance
C. low reliability and stability
D. low reliability and low stability
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DR K.L.DEEPTHI RCP

19. Q18
Collagen Shields are:
A. MONOLITHIC SYSTEMS
B. IUD’S
C. OCCUSERTS
D. TRANSDERMAL PATCHES
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DR K.L.DEEPTHI RCP

20. Q19
Cyclodextrins is useful to increase -----of drug in
eye:
A. solubility
B. permeability
C. Contactability
D. all of the above
20
DR K.L.DEEPTHI RCP

21. Q20
MICROBALLOONS ARE:
A. hollow microspheres
B. microspheres with prolonged GRT
C. EUDRGIT containing microspheres
D. all of the above
21
DR K.L.DEEPTHI RCP

22. Q2I
1.Drugs Unsuitable for controlled release.
A.penicillin G,
B.Furosemide
C.Diazepam
D. All of the above
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DR K.L.DEEPTHI RCP

23. Q22
Mucocilliary clearance is
A. A barrier to nasal absorption
B. Not a barrier to nasal absorption
C. It is protective in function
D. It is a barrier to nasal absorption but also
protective in function
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DR K.L.DEEPTHI RCP