Glaucoma is a group of diseases that cause damage to the retinal ganglion cells from increased intraocular pressure. It is a leading cause of blindness. The anatomy involves aqueous humor production and outflow, with factors like age, race, family history, drugs, and surgery affecting IOP. Normal IOP is typically below 21 mmHg. Treatment options include beta blockers, alpha agonists, carbonic anhydrase inhibitors, and prostaglandins, while surgical options include laser trabeculoplasty and filtration procedures. Screening is recommended for those over 40, with a family history, underlying diseases, on certain medications, history of eye trauma, or signs/symptoms of suspected glaucoma.