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Immunity and Surgery
Dr Basit Qureshi
Assistant Professor, Surgical Unit I
SIMS/Services Hospital, Lahore
Importance of immunity in surgery
• Wound Healing
• Early Post operative recovery
• Prevention against infections
– abdominal tuberculosis and its complications
– Amebic Liver Abscess
– Typhoid fever and its complication
Common causes of immunocompromised
status of surgical patients
• Diabetes
• HIV (AIDS) especially in IV drug abuser
• Advanced Malignancy
Common presentation to surgeon of
immunocompromised patients
• Diabetic Foot
• Mycotic Anerysm
• Abscess Formation
• Lymphadenopathy
OverWhelming Post Splenectomy Infection
(OPSI)
• Due to decreased immunity against
encapsulated micro organisms
– Hemophilus Influenza
– Pneumococcus
– Meningococcus
Immunosuppression
• Important after transplantation surgery to
prevent graft rejection
Immunotherapy
• Treatment of disease by inducing, enhancing,
or suppressing an immune response
– e.g. against malignancies
THANK YOU

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[Gen. surg] immunity and surgery from SIMS Lahore

  • 1. Immunity and Surgery Dr Basit Qureshi Assistant Professor, Surgical Unit I SIMS/Services Hospital, Lahore
  • 2. Importance of immunity in surgery • Wound Healing • Early Post operative recovery • Prevention against infections – abdominal tuberculosis and its complications – Amebic Liver Abscess – Typhoid fever and its complication
  • 3. Common causes of immunocompromised status of surgical patients • Diabetes • HIV (AIDS) especially in IV drug abuser • Advanced Malignancy
  • 4. Common presentation to surgeon of immunocompromised patients • Diabetic Foot • Mycotic Anerysm • Abscess Formation • Lymphadenopathy
  • 5. OverWhelming Post Splenectomy Infection (OPSI) • Due to decreased immunity against encapsulated micro organisms – Hemophilus Influenza – Pneumococcus – Meningococcus
  • 6. Immunosuppression • Important after transplantation surgery to prevent graft rejection
  • 7. Immunotherapy • Treatment of disease by inducing, enhancing, or suppressing an immune response – e.g. against malignancies