Fixed Action Pattern (FAP) is a series or sequence of acts that occur behaviorally in animals. it is also known as instinctive behaviour as it is determined by gene of an organism and exhibited automatically without having any prior experience.
Animal behaviour includes all the ways animals interact with other organisms and the physical environment. It is defined as a change in the activity of an organism in response to a stimulus.
types of orientation- primary and secondary, different types of kinesis - orthokinesis and klinokinesis and taxis - tropotaxis, klinotaxis, menotaxis, transverse orientation, dosal light reaction and ventral light reaction
Animal behaviour includes all the ways animals interact with other organisms and the physical environment. It is defined as a change in the activity of an organism in response to a stimulus.
types of orientation- primary and secondary, different types of kinesis - orthokinesis and klinokinesis and taxis - tropotaxis, klinotaxis, menotaxis, transverse orientation, dosal light reaction and ventral light reaction
Two broad categories of behaviors are Proximate and Ultimate behaviour. The presentation gives a brief introduction on Proximate and Ultimate causes of behaviour
Social organization and social behaviour in insectsPoojaVishnoi7
Introduction
Properties of a society
Advantages of a society
Disadvantages of a society
Social organisation and social behaviour in insects:-
1. Termites
2.Honeybees
3.Ants
4.Yellow wasp
Ethology is the scientific and objective study of animal behaviour, usually with a focus on behaviour under natural conditions, and viewing behaviour as an evolutionarily adaptive trait. Ethology is a branch of zoology concerned with the study of animal behavior. Ethologists take a comparative approach, studying behaviors ranging from kinship, cooperation, and parental investment, to conflict, sexual selection, and aggression across a variety of species.
Food selection depends on the energy strategy of the feeder. The food size, quantity and quality varies with species to species and also depends on the ability of feeder, its body size etc.
Feeders are either specialists or opportunists. Food selection depends on competitive principle, learned aversion and food energy budget.
Two broad categories of behaviors are Proximate and Ultimate behaviour. The presentation gives a brief introduction on Proximate and Ultimate causes of behaviour
Social organization and social behaviour in insectsPoojaVishnoi7
Introduction
Properties of a society
Advantages of a society
Disadvantages of a society
Social organisation and social behaviour in insects:-
1. Termites
2.Honeybees
3.Ants
4.Yellow wasp
Ethology is the scientific and objective study of animal behaviour, usually with a focus on behaviour under natural conditions, and viewing behaviour as an evolutionarily adaptive trait. Ethology is a branch of zoology concerned with the study of animal behavior. Ethologists take a comparative approach, studying behaviors ranging from kinship, cooperation, and parental investment, to conflict, sexual selection, and aggression across a variety of species.
Food selection depends on the energy strategy of the feeder. The food size, quantity and quality varies with species to species and also depends on the ability of feeder, its body size etc.
Feeders are either specialists or opportunists. Food selection depends on competitive principle, learned aversion and food energy budget.
Animal behavior includes all the ways animals interact with other organisms and the physical environment. Behavior can also be defined as a change in the activity of an organism in response to a stimulus, an external or internal cue or combo of cues. ... Behavior is shaped by natural selection.
Plant responses and movements by aram omer sorkanaramomer
This is a presentation about Plant responses and movements to external environment factor or external stimulus.
Prepared by Aram omer sorkan
University of Sulaimani
School of Science
Department of Biology
The rearing of silkworms for the production of silk
is called sericulture.
India is the second largest silk producing country in
the world next to China.
Silk is the secretion from the salivary glands which
are found on both sides of the alimentary canal of
silkworm larvae and this secretion hardens into
fine threads called silk.
Whenever the population of any insect species
increases significantly, so as it causes
appreciable economic loss, is known as pest.
Pest control is important as they cause heavy economic loss.
looking after the eggs or young until they are independent to defend from predators is known as parental care.
Amphibians show great diversity in Parental care.
learning is a specific change or modification in behavior involving the nervous system as an result of experience with an external event or series of events in a individuals life.
An ecological pyramid is a graphical representation designed to show the biomass or bio-productivity at each trophic level in a given ecosystem. there are three types of pyramid- 1) Pyramid of number.2) Pyramid of biomass 3) Pyramid of energy.
Immunity is the ability of the body to protect against all types of foreign bodies like bacteria, virus, toxic substances etc. As it protects us from diseases it is also called disease resistance. Immunity is done by immune system which is a complex network of lymphoid organs such as bone marrow, thymus, spleen etc. It is mainly of two types- Natural and Acquired immunity.
When a perfectly harmless animal resembles in its colour and shape, with a well protected species, the phenomenon is called mimicry.
The concept of mimicry was first given by H. W. Bates in 1862.
Mimicry is an important feature of organism which protect the animals against enemies. Mimicry often used as self defense which increases the survival value of organisms.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
3. A fix action pattern is a series or sequence of acts
that occur behaviorally in animals. The sequence is
unchangeable and will be carried out to completion
once started, regardless of changes in the original
stimulus.
FAP is also known as instinctive behavior because
it is determined by gene of an organism.
4. It is found to be same in all members of a species. E.g. Egg
rolling behavior in graylag goose
The behavior is performed correctly the 1st time without prior
experience.
It is stimulated by a sign stimulus.
Once started, run to completion with no further input
5. An automatic movement made by an animal towards
or away from a stimulus.
A taxis is said to be positive if the animal heads
directly towards the stimulus, negative if away from it.
Types-
1) Phototaxis
2) Chemotaxis
3) Geotaxis
6. 1) Phototaxis – movement toward or away from light.
It is of 2 types- positive and negative phototaxis
Positive if moves towards a light.
E.g. flight of moth towards a light.
Negative if moves away from light.
E.g. Cockroach running for cover
when lights are turned on.
2) Chemotaxis – It is the
movement of an organism in
response to a chemical stimulus.
It is of two types- positive and
negative Chemotaxis.
Positive if the movement is
toward a higher concentration of
the chemical and negative if the
movement is in opposite
direction.
7. 3. Geotaxis- movement toward or away from gravity.
a) Positive if movement is toward gravity.
E.g.- plant root
b) Negative if movement is away from gravity.
E.g.- tree growing taller
8. Kinesis is a response to an environmental
condition by changing the rate at which an
activity is performed.
It is of two types
1) Orthokinesis – Here a relationship exists
between the speed of locomotion and the
intensity of stimulation.
2) Klinokinesis- It deals with the undirected
changes in the turning from side to side.
E.g. Humidity kinesis in wood louse
9. A reflex is an automatic response of part of the body to a stimulus.
The response is inborn.
They are rapid acts that require no conscious control.
Eg. The withdrawl reflex of the hand from a hot stove occurs before
we are consciously aware of the temperature.
Reflexes can be unconditioned and conditioned.
10. Any behaviour is instinctive
if it is performed without
being based upon prior
experience.
Example- newly hatched sea
turtles automatically move
toward the ocean.
Shaking water from wet fur
in dog.
11. Releasers, also called sign stimuli, are those stimuli that are
capable of releasing FAP of those animal.
Konrad Lorenz (1972) was the first biologist to identify sign
stimuli.
Types of releasers
It is of 3 types-
1. Visual releasers-
They are morphological
characters that are
displayed to elicit
response.
E.g. Peacock dances and
displays its beautiful
feathers to attract Peahen.
12. 2. Auditory releasers-
Song birds such as Cuckoo,
nightingales establish their
territory and attract the female
for mating by singing, often for
several days.
3. Chemical releasers-
it is released in the
atmosphere & act as releasers
on the individual of same or
other species.
It can be sex pheromone, trail
pheromone etc.