Nuclear diagnostic imaging allows physicians to see how the body is functioning internally by injecting radioactive material called radiopharmaceuticals and detecting the gamma radiation emitted using gamma cameras. The document compares the efficacy of two gamma cameras - the Hybrid Compact Gamma Camera (HCGC) and the XRI-UNO CdTe semiconductor-based detector. Images of a cannula tube filled with radioactive material taken with each camera showed that the HCGC image had higher spatial resolution. The initial studies encourage further evaluation of the HCGC for use in surgical settings over the XRI-UNO.