This document describes the development and initial testing of a hybrid gamma-optical camera for diagnostic imaging applications. The hybrid camera combines an optical camera with a gamma camera in an aligned configuration, allowing for high spatial resolution scintigraphic imaging fused with anatomical context from optical images. Initial tests show the camera has sub-millimeter spatial resolution and a sensitivity suitable for intraoperative use. Images of a simulated lymphatic vessel filled with a radioactive tracer demonstrate the camera can accurately localize radioactive uptake with anatomical guidance from the optical image. The hybrid camera design shows potential for applications like sentinel lymph node mapping during surgery.