The document discusses De Quervain's tenosynovitis, which is an inflammation of the tendons that control thumb movement. It affects the first dorsal compartment of the wrist. Symptoms include radial-sided wrist pain that worsens with gripping. Diagnosis is made clinically based on symptoms and physical exam findings. Treatment begins conservatively with splinting, injections, and medications, and sometimes requires surgical release of the first dorsal compartment if conservative measures fail. Complications of surgery can include nerve damage or recurrence if not fully decompressed.