Exanthema (rash) in pakistan
Rashes in the newborn period are common. While a comprehensive list of all possible rashes can not be made here, following is the list of some of the common rashes seen in newborns in Pakistan.
Progeria is a rare genetic condition where aging begins in childhood, causing abnormal physical development. Symptoms include premature wrinkling and loss of hair and life expectancy is usually 13 years. Progeria is not inherited in most cases and has no cure.
"Alone we are rare, together we are strong." Let us support living with rare disorders. Today on "World Rare Disorder Day" (28 Feb), let us make ourselves aware of the challenges, hopes and needs of those living with rare diseases
Down Syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of a third copy of chromosome 21. It is the most common chromosome abnormality in humans, occurring in about 1 in 699 births in the US. Down Syndrome can be broken into three main types - trisomy 21 which accounts for 95% of cases, translocation Down Syndrome which is 3-4% of cases, and mosaic Down Syndrome which is less than 1% of cases. Physical features include stunted growth, slanted eyes, low-set ears, flattened nose, smaller teeth and shortened hands. Individuals with Down Syndrome often have intellectual disabilities ranging from mild to moderate and may experience delays in speech, motor skills,
Multiple Sclerosis Syndrome is a disease that affects the central nervous system and causes physical disability. It is believed to be caused by a combination of genetic and environmental factors that cause the immune system to attack the protective myelin sheathing of neurons. Studies have found that the hormone estriol, present in high amounts during pregnancy, may help reduce lesions in the brains of women with MS. Initial studies on 12 women saw reductions in brain lesions while taking estriol, but the lesions returned to original sizes after treatment ended. Further research is still needed to determine if estriol provides long-term benefits and consistently helps reduce MS symptoms.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Down syndrome is a chromosomal condition caused by the presence of an extra copy of chromosome 21. It is often associated with delays in cognitive ability and physical growth. Individuals with Down syndrome typically have an IQ around 50, compared to 100 for those without it, and many have severe intellectual disabilities.
This document discusses Down syndrome, including its causes, features in newborns, diagnosis, and management. Down syndrome results from extra genetic material from chromosome 21, which can occur through trisomy 21, mosaicism, or translocation. Affected newborns commonly have hypotonia, slanted eyes, and other physical signs. Prenatal screening and testing can detect Down syndrome. Early intervention aims to support development and address any health issues.
This document discusses several diseases including their causes and symptoms. It mentions that HIV is a virus spread through body fluids that can destroy immune cells over time. Ebola is a severe, often fatal illness transmitted between humans and animals. Influenza attacks the respiratory system and vaccination provides the best defense. Hepatitis causes liver inflammation and jaundice. Psoriasis is an autoimmune disease that affects many in the US. Some genetic diseases result from mutations in DNA that can be caused by environmental factors or occur during cell division. Cancer often stems from a series of p53 gene mutations allowing unchecked cell growth. The document stresses the importance of health and encourages taking care of one's health and family.
Progeria is a rare genetic condition where aging begins in childhood, causing abnormal physical development. Symptoms include premature wrinkling and loss of hair and life expectancy is usually 13 years. Progeria is not inherited in most cases and has no cure.
"Alone we are rare, together we are strong." Let us support living with rare disorders. Today on "World Rare Disorder Day" (28 Feb), let us make ourselves aware of the challenges, hopes and needs of those living with rare diseases
Down Syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of a third copy of chromosome 21. It is the most common chromosome abnormality in humans, occurring in about 1 in 699 births in the US. Down Syndrome can be broken into three main types - trisomy 21 which accounts for 95% of cases, translocation Down Syndrome which is 3-4% of cases, and mosaic Down Syndrome which is less than 1% of cases. Physical features include stunted growth, slanted eyes, low-set ears, flattened nose, smaller teeth and shortened hands. Individuals with Down Syndrome often have intellectual disabilities ranging from mild to moderate and may experience delays in speech, motor skills,
Multiple Sclerosis Syndrome is a disease that affects the central nervous system and causes physical disability. It is believed to be caused by a combination of genetic and environmental factors that cause the immune system to attack the protective myelin sheathing of neurons. Studies have found that the hormone estriol, present in high amounts during pregnancy, may help reduce lesions in the brains of women with MS. Initial studies on 12 women saw reductions in brain lesions while taking estriol, but the lesions returned to original sizes after treatment ended. Further research is still needed to determine if estriol provides long-term benefits and consistently helps reduce MS symptoms.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Down syndrome is a chromosomal condition caused by the presence of an extra copy of chromosome 21. It is often associated with delays in cognitive ability and physical growth. Individuals with Down syndrome typically have an IQ around 50, compared to 100 for those without it, and many have severe intellectual disabilities.
This document discusses Down syndrome, including its causes, features in newborns, diagnosis, and management. Down syndrome results from extra genetic material from chromosome 21, which can occur through trisomy 21, mosaicism, or translocation. Affected newborns commonly have hypotonia, slanted eyes, and other physical signs. Prenatal screening and testing can detect Down syndrome. Early intervention aims to support development and address any health issues.
This document discusses several diseases including their causes and symptoms. It mentions that HIV is a virus spread through body fluids that can destroy immune cells over time. Ebola is a severe, often fatal illness transmitted between humans and animals. Influenza attacks the respiratory system and vaccination provides the best defense. Hepatitis causes liver inflammation and jaundice. Psoriasis is an autoimmune disease that affects many in the US. Some genetic diseases result from mutations in DNA that can be caused by environmental factors or occur during cell division. Cancer often stems from a series of p53 gene mutations allowing unchecked cell growth. The document stresses the importance of health and encourages taking care of one's health and family.
Down syndrome is caused by the presence of an extra chromosome 21. It is neither dominant nor recessive as it results from an error in chromosome translation. The amyloid precursor protein gene on chromosome 21 may cause Down syndrome by interfering with cell signaling and leading to cell death. People with Down syndrome have distinct physical features like a flattened face and webbed fingers or toes. Treatments focus on managing any related health issues and providing early intervention programs. Life expectancy is around 50 years on average.
This document summarizes common genetic disorders in Yorkshire Terriers, including musculoskeletal disorders like patellar luxation and Legg-Calvé-Perthes disease, heart disorders like patent ductus arteriosus, eye disorders such as retinal dysplasia and cataracts, nervous system disorders including hydrocephalus and shaker dog disease, skin disorders like dermoid sinus and hypotrichosis, and blood disorders like von Willebrand's disease. It emphasizes that liver shunts, tracheal collapse, patellar luxation, and retinal dysplasia are particularly common in the breed. Breeders are advised to test for these conditions and provide a health guarantee.
Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It was first described in 1866 by Dr. John Langdon Down and the chromosome abnormality was discovered in 1959. Individuals with Down syndrome typically have physical and intellectual disabilities including an average IQ of 50, equivalent to an 8 or 9 year old child. They also have an increased risk of health problems such as congenital heart disease and leukemia. Life expectancy for individuals with Down syndrome has increased from 12 years in 1912 to 50-60 years currently with improved medical care.
Down syndrome is a genetic disorder caused by the presence of an extra chromosome 21. It is characterized by intellectual disability and developmental delays, a distinct facial appearance, and weak muscle tone. There are three main types - trisomy 21, translocation, and mosaicism. While people with Down syndrome experience cognitive delays, the intellectual disability is usually mild to moderate. With proper support and care, people with Down syndrome can learn skills, go to school, work, and live independently or within a supportive community.
Down syndrome is the most common cause of developmental disability in newborns, occurring due to the presence of an extra chromosome. It affects 1 in 800 live births and the risk increases with the age of the mother. Symptoms include a flat nose, small mouth, slanting eyes, as well as adverse effects on hearing and sight like frequent ear infections leading to hearing loss requiring aids. While there is no prevention or cure, screening and diagnostic tests can determine the risk and manage symptoms through regular checkups and medication. Support is available through organizations providing information, love, structure and community.
Down syndrome is caused by trisomy 21, occurring in approximately 1 in 1000 live births. It results from errors in cell division during meiosis. Clinically, it is characterized by facial features like an upward slant of the eyes, a flat facial profile, and intellectual disability. Complications can include heart defects, hearing or vision problems, gastrointestinal issues, and other conditions. Management involves monitoring for associated medical issues and providing therapies to support development. The lifespan for individuals with Down syndrome has increased in recent decades due to improved medical care.
Down syndrome is caused by an extra chromosome 21. It has several characteristic physical features and causes intellectual disabilities. Eye problems are very common in Down syndrome, including squints, refractive errors like myopia and astigmatism, and eye infections. Regular eye exams from birth are important to monitor vision and treat any issues early. Common treatments include glasses, eye muscle surgery, and occasionally cataract surgery.
This document discusses Down syndrome (DS), providing details on its diagnosis, characteristics, and management. It describes the key physical features of DS, including upward slanting eyes, small ears, short neck, short broad hands, and wide space between the first and second toes. It outlines common health issues associated with DS such as congenital heart defects, gastrointestinal problems, hearing problems, thyroid issues, and developmental delays. It explains that DS is caused by trisomy of chromosome 21 and describes the different genetic subtypes. The document stresses the importance of early intervention programs for managing DS and improving development.
Down syndrome is a genetic disorder caused by a triplication of chromosome 21. It was first described in 1886 by Dr. John Langdon Down, who noted common characteristics in a group of people that resembled those of Eastern races, leading it also to be called mongolism. Risk factors include infectious diseases or crises during early pregnancy as well as increased maternal age. People with Down syndrome often have limited initiative, decreased inhibition, resistance to change, and low responsiveness in areas like attention, intelligence, memory, and language. Parents are encouraged to learn about Down syndrome, love and play with their child, encourage independence, stay involved in their education, and maintain patience and hope.
Waardenburg Syndrome is an inherited disorder characterized by hearing loss and changes in hair and skin pigmentation. There are four types, with types I and II being most common. It is caused by a dominant gene mutation and symptoms may include deafness, pale eye color, and patchy hair loss. While symptoms are present at birth, diagnosis is usually made in infancy through tests like audiometry and genetic testing. Treatment focuses on managing hearing loss and other symptoms, as there is no cure for the underlying condition.
The document provides an overview of Down syndrome, including its history, types, physical characteristics, diagnosis, informing parents, and caring for an affected child. It discusses John Langdon Down's initial description in 1866 and the recognition as a genetic disorder in 1959. It covers the three types of trisomy 21, translocation, and mosaicism. Key physical signs include a flat face, slanted eyes, small ears and hands/feet. Parents should be informed clearly using understandable language and focusing on positive aspects while avoiding strict prognosis. Acceptance, stimulation, social integration and support are important for caring for a child with Down syndrome.
Down syndrome is a genetic condition caused by the presence of an extra chromosome 21. It causes delays in physical and intellectual development. The majority of cases are caused by nondisjunction during cell division resulting in 47 total chromosomes rather than the usual 46. Clinical manifestations include mild to moderate intellectual disability, delayed development, congenital heart defects, vision and hearing problems, and increased risk of infections. Nursing care focuses on monitoring for complications, promoting development, and educating families on managing care.
Down syndrome is a genetic disorder caused by the presence of an extra chromosome 21. It is characterized by cognitive delays, slower physical development, and distinctive facial features. Individuals with Down syndrome often have health issues such as heart defects, hearing or vision problems, thyroid issues, and an increased risk of Alzheimer's disease. Their development follows a specific pattern, with relative strengths in social skills but delays in motor skills, language, and short-term verbal memory. Early intervention and education can help maximize their learning potential over their lifetime.
This presentation contains detailed knowledge about Down's Syndrome its types, clinical presentation, diagnosis, medical and physio therapeutic management of the condition.
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small “packages” of genes in the body. They determine how a baby’s body forms and functions as it grows during pregnancy and after birth. Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy.’ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.
Down Syndrome is caused by the presence of an extra chromosome 21 or part of an extra chromosome 21. It is also known as Trisomy 21. Common symptoms include a round face, broad head, excess joint laxity, and an IQ range of 10-70. The incidence rates are 1 per 800 to 1 per 1000 births depending on the mother's age, with older mothers having higher risks. While there is no prevention or cure, testing like amniocentesis can detect Down Syndrome during pregnancy. Support organizations like the National Down Syndrome Society provide help for children with Down Syndrome.
The document provides an overview of Down syndrome including definitions, features in newborns, common abnormalities, and age-specific healthcare guidelines. It notes that Down syndrome is caused by trisomy of chromosome 21 and occurs in approximately 1 in 660 births. Newborns with Down syndrome typically exhibit certain physical features such as slanted eyes and hypotonia. Common abnormalities include heart defects, gastrointestinal issues, hearing problems, and thyroid disorders. The document outlines guidelines for healthcare from the neonatal period through adulthood.
Down's Syndrome, also known as trisomy 21, is a genetic condition where a person has 47 chromosomes instead of the usual 46, causing mental retardation and other problems ranging from mild to serious. Common physical signs include a flattened nose, small ears and mouth, upward slanting eyes, and short hands and fingers. Risk factors include increased maternal age and parents being carriers of the translocation. While there is no cure, early intervention and treatment of complications like heart defects can help development.
Down syndrome, also known as trisomy 21, is a genetic disorder caused by a third copy of chromosome 21. It is associated with physical growth delays and distinctive facial features. People with Down syndrome typically have mild to moderate intellectual disabilities, with an average IQ of around 50. While Down syndrome is not caused by environmental factors or a parent's genetics, it can be identified during pregnancy through screening and testing. Individuals with Down syndrome often require regular health checks as they are at greater risk for health problems and have reduced life expectancy compared to the general population.
This document provides details on the case of an 8 month old female child named Azma who presented with recurrent cold, cough, loose motions, and rapid breathing. It summarizes her birth history, developmental milestones, family history, clinical features, genetic causes, common health issues, diagnostic criteria, management, and prognosis of Down syndrome.
Surgical Complications of Roundworm InfestationKETAN VAGHOLKAR
Round worm infestation is common in the tropical countries. Ascaris lumbricoides can cause a variety of complications in the abdomen ranging from colic to perforative peritonitis. As majority of abdominal complications require surgical intervention awareness of the complications is pivotal to the attending surgeon. The surgical complications of roundworm infestation are discussed in this article.
Adverse drug reactions (ADRs) can be categorized into four main types. Type A reactions are common and predictable side effects related to the drug's pharmacological action, such as dry mouth from atropine. Type B reactions are unpredictable and unrelated to the drug's action, often caused by allergies or idiosyncrasies. Type C reactions involve chronic effects from long-term use such as dependence or withdrawal. Type D reactions are very rare delayed effects like carcinogenesis or teratogenesis that may take decades to develop. The document provides examples and classifications of each ADR type.
Down syndrome is caused by the presence of an extra chromosome 21. It is neither dominant nor recessive as it results from an error in chromosome translation. The amyloid precursor protein gene on chromosome 21 may cause Down syndrome by interfering with cell signaling and leading to cell death. People with Down syndrome have distinct physical features like a flattened face and webbed fingers or toes. Treatments focus on managing any related health issues and providing early intervention programs. Life expectancy is around 50 years on average.
This document summarizes common genetic disorders in Yorkshire Terriers, including musculoskeletal disorders like patellar luxation and Legg-Calvé-Perthes disease, heart disorders like patent ductus arteriosus, eye disorders such as retinal dysplasia and cataracts, nervous system disorders including hydrocephalus and shaker dog disease, skin disorders like dermoid sinus and hypotrichosis, and blood disorders like von Willebrand's disease. It emphasizes that liver shunts, tracheal collapse, patellar luxation, and retinal dysplasia are particularly common in the breed. Breeders are advised to test for these conditions and provide a health guarantee.
Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It was first described in 1866 by Dr. John Langdon Down and the chromosome abnormality was discovered in 1959. Individuals with Down syndrome typically have physical and intellectual disabilities including an average IQ of 50, equivalent to an 8 or 9 year old child. They also have an increased risk of health problems such as congenital heart disease and leukemia. Life expectancy for individuals with Down syndrome has increased from 12 years in 1912 to 50-60 years currently with improved medical care.
Down syndrome is a genetic disorder caused by the presence of an extra chromosome 21. It is characterized by intellectual disability and developmental delays, a distinct facial appearance, and weak muscle tone. There are three main types - trisomy 21, translocation, and mosaicism. While people with Down syndrome experience cognitive delays, the intellectual disability is usually mild to moderate. With proper support and care, people with Down syndrome can learn skills, go to school, work, and live independently or within a supportive community.
Down syndrome is the most common cause of developmental disability in newborns, occurring due to the presence of an extra chromosome. It affects 1 in 800 live births and the risk increases with the age of the mother. Symptoms include a flat nose, small mouth, slanting eyes, as well as adverse effects on hearing and sight like frequent ear infections leading to hearing loss requiring aids. While there is no prevention or cure, screening and diagnostic tests can determine the risk and manage symptoms through regular checkups and medication. Support is available through organizations providing information, love, structure and community.
Down syndrome is caused by trisomy 21, occurring in approximately 1 in 1000 live births. It results from errors in cell division during meiosis. Clinically, it is characterized by facial features like an upward slant of the eyes, a flat facial profile, and intellectual disability. Complications can include heart defects, hearing or vision problems, gastrointestinal issues, and other conditions. Management involves monitoring for associated medical issues and providing therapies to support development. The lifespan for individuals with Down syndrome has increased in recent decades due to improved medical care.
Down syndrome is caused by an extra chromosome 21. It has several characteristic physical features and causes intellectual disabilities. Eye problems are very common in Down syndrome, including squints, refractive errors like myopia and astigmatism, and eye infections. Regular eye exams from birth are important to monitor vision and treat any issues early. Common treatments include glasses, eye muscle surgery, and occasionally cataract surgery.
This document discusses Down syndrome (DS), providing details on its diagnosis, characteristics, and management. It describes the key physical features of DS, including upward slanting eyes, small ears, short neck, short broad hands, and wide space between the first and second toes. It outlines common health issues associated with DS such as congenital heart defects, gastrointestinal problems, hearing problems, thyroid issues, and developmental delays. It explains that DS is caused by trisomy of chromosome 21 and describes the different genetic subtypes. The document stresses the importance of early intervention programs for managing DS and improving development.
Down syndrome is a genetic disorder caused by a triplication of chromosome 21. It was first described in 1886 by Dr. John Langdon Down, who noted common characteristics in a group of people that resembled those of Eastern races, leading it also to be called mongolism. Risk factors include infectious diseases or crises during early pregnancy as well as increased maternal age. People with Down syndrome often have limited initiative, decreased inhibition, resistance to change, and low responsiveness in areas like attention, intelligence, memory, and language. Parents are encouraged to learn about Down syndrome, love and play with their child, encourage independence, stay involved in their education, and maintain patience and hope.
Waardenburg Syndrome is an inherited disorder characterized by hearing loss and changes in hair and skin pigmentation. There are four types, with types I and II being most common. It is caused by a dominant gene mutation and symptoms may include deafness, pale eye color, and patchy hair loss. While symptoms are present at birth, diagnosis is usually made in infancy through tests like audiometry and genetic testing. Treatment focuses on managing hearing loss and other symptoms, as there is no cure for the underlying condition.
The document provides an overview of Down syndrome, including its history, types, physical characteristics, diagnosis, informing parents, and caring for an affected child. It discusses John Langdon Down's initial description in 1866 and the recognition as a genetic disorder in 1959. It covers the three types of trisomy 21, translocation, and mosaicism. Key physical signs include a flat face, slanted eyes, small ears and hands/feet. Parents should be informed clearly using understandable language and focusing on positive aspects while avoiding strict prognosis. Acceptance, stimulation, social integration and support are important for caring for a child with Down syndrome.
Down syndrome is a genetic condition caused by the presence of an extra chromosome 21. It causes delays in physical and intellectual development. The majority of cases are caused by nondisjunction during cell division resulting in 47 total chromosomes rather than the usual 46. Clinical manifestations include mild to moderate intellectual disability, delayed development, congenital heart defects, vision and hearing problems, and increased risk of infections. Nursing care focuses on monitoring for complications, promoting development, and educating families on managing care.
Down syndrome is a genetic disorder caused by the presence of an extra chromosome 21. It is characterized by cognitive delays, slower physical development, and distinctive facial features. Individuals with Down syndrome often have health issues such as heart defects, hearing or vision problems, thyroid issues, and an increased risk of Alzheimer's disease. Their development follows a specific pattern, with relative strengths in social skills but delays in motor skills, language, and short-term verbal memory. Early intervention and education can help maximize their learning potential over their lifetime.
This presentation contains detailed knowledge about Down's Syndrome its types, clinical presentation, diagnosis, medical and physio therapeutic management of the condition.
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small “packages” of genes in the body. They determine how a baby’s body forms and functions as it grows during pregnancy and after birth. Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy.’ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.
Down Syndrome is caused by the presence of an extra chromosome 21 or part of an extra chromosome 21. It is also known as Trisomy 21. Common symptoms include a round face, broad head, excess joint laxity, and an IQ range of 10-70. The incidence rates are 1 per 800 to 1 per 1000 births depending on the mother's age, with older mothers having higher risks. While there is no prevention or cure, testing like amniocentesis can detect Down Syndrome during pregnancy. Support organizations like the National Down Syndrome Society provide help for children with Down Syndrome.
The document provides an overview of Down syndrome including definitions, features in newborns, common abnormalities, and age-specific healthcare guidelines. It notes that Down syndrome is caused by trisomy of chromosome 21 and occurs in approximately 1 in 660 births. Newborns with Down syndrome typically exhibit certain physical features such as slanted eyes and hypotonia. Common abnormalities include heart defects, gastrointestinal issues, hearing problems, and thyroid disorders. The document outlines guidelines for healthcare from the neonatal period through adulthood.
Down's Syndrome, also known as trisomy 21, is a genetic condition where a person has 47 chromosomes instead of the usual 46, causing mental retardation and other problems ranging from mild to serious. Common physical signs include a flattened nose, small ears and mouth, upward slanting eyes, and short hands and fingers. Risk factors include increased maternal age and parents being carriers of the translocation. While there is no cure, early intervention and treatment of complications like heart defects can help development.
Down syndrome, also known as trisomy 21, is a genetic disorder caused by a third copy of chromosome 21. It is associated with physical growth delays and distinctive facial features. People with Down syndrome typically have mild to moderate intellectual disabilities, with an average IQ of around 50. While Down syndrome is not caused by environmental factors or a parent's genetics, it can be identified during pregnancy through screening and testing. Individuals with Down syndrome often require regular health checks as they are at greater risk for health problems and have reduced life expectancy compared to the general population.
This document provides details on the case of an 8 month old female child named Azma who presented with recurrent cold, cough, loose motions, and rapid breathing. It summarizes her birth history, developmental milestones, family history, clinical features, genetic causes, common health issues, diagnostic criteria, management, and prognosis of Down syndrome.
Surgical Complications of Roundworm InfestationKETAN VAGHOLKAR
Round worm infestation is common in the tropical countries. Ascaris lumbricoides can cause a variety of complications in the abdomen ranging from colic to perforative peritonitis. As majority of abdominal complications require surgical intervention awareness of the complications is pivotal to the attending surgeon. The surgical complications of roundworm infestation are discussed in this article.
Adverse drug reactions (ADRs) can be categorized into four main types. Type A reactions are common and predictable side effects related to the drug's pharmacological action, such as dry mouth from atropine. Type B reactions are unpredictable and unrelated to the drug's action, often caused by allergies or idiosyncrasies. Type C reactions involve chronic effects from long-term use such as dependence or withdrawal. Type D reactions are very rare delayed effects like carcinogenesis or teratogenesis that may take decades to develop. The document provides examples and classifications of each ADR type.
Strongyloides is a parasitic roundworm infection that was first described in French troops in Vietnam in the late 19th century. It is most common in tropical areas. Most infections are asymptomatic, but some can become severe or critical if left untreated. The parasite enters the body through exposed skin and has a complex life cycle involving an internal autoinfection that can cause chronic or disseminated infections in immunosuppressed individuals. Diagnosis is usually by microscopic identification of larvae in stool samples. Treatment is recommended for all infected individuals due to risk of severe disease.
Strongyloides stercoralis is an intestinal parasitic nematode that can cause strongyloidiasis in humans. It has a unique life cycle involving both free-living and parasitic stages. In the parasitic stage, the worm resides in the small intestine and can spread throughout the body, potentially causing disseminated infection. Diagnosis is made by identifying larvae in stool samples or biopsy specimens. Transplant patients are at higher risk of severe hyperinfection due to immunosuppression. Screening and treatment prior to transplantation is important for prevention.
Strongyloides stercoralis is a parasitic nematode that can cause the disease strongyloidiasis. It has a complex life cycle involving both free-living and parasitic stages. The parasite penetrates intact skin and has two life cycles - an intestinal cycle that can persist for decades, and a pulmonary cycle seen in severe infections. Symptoms range from mild skin symptoms to severe pneumonia-like symptoms. Diagnosis involves examining stool, sputum, or gastric/duodenal samples for eggs or larval stages. Treatment involves ivermectin and albendazole. Prevention relies on good hygiene and sanitation practices.
1. Miliaria, commonly known as heat rash, is a skin condition caused by blocked sweat ducts. It presents as tiny red bumps or blisters on the skin that are often very itchy or painful.
2. Miliaria typically affects skin folds like the neck, armpits, elbows, and knees. It occurs when sweat cannot escape through clogged pores, causing localized swelling in the upper layers of skin.
3. The rash usually appears within hours of exposure to high heat and humidity. It is self-limiting and resolves once the skin is cooled and sweat ducts are unclogged. Treatment focuses on keeping skin dry and avoiding excessive sweating through
This document provides information on assessing the health of a newborn infant, including pertinent maternal history, physical assessment findings, and physiologic functioning. Key areas of assessment include posture, length, weight, skin features, head circumference, fontanels, sutures, and facial features like eyes. Communication of this assessment data helps ensure effective nursing care is provided to the neonate.
This document provides guidance on performing a neonatal examination within the first 24 hours of birth. It describes assessing the infant's vital signs, appearance, skin color, head, length/weight/head circumference, gestational age, and performing a physical exam. The exam involves inspecting the skin for any abnormalities, checking the fontanelles, listening to the heart and lungs, and looking for any signs of distress, jaundice or abnormalities. Growth measurements are plotted on charts and the gestational age is estimated based on physical criteria and scores.
This document provides guidance on performing a neonatal examination within the first 24 hours of birth. It describes examining the infant's vital signs, appearance, skin color, head, neck, face, ears, and eyes. Specific things to note include gestational age, weight, any abnormalities present, fontanelles, skin rashes, bruising or bleeding. The goal is to evaluate the infant's overall health and identify any issues that require follow up or treatment.
This document discusses and compares two diseases: chicken pox and anorexia nervosa. Chicken pox is a highly contagious viral disease that causes an itchy rash. It spreads through contact with infected individuals and can be prevented through vaccination. Anorexia nervosa is a psychological disorder characterized by an obsessive fear of gaining weight and refusal to eat. It has complex cultural, biological, and psychological causes and can lead to severe physical and mental health issues if not properly treated through hospitalization and monitored recovery programs. Both diseases are most common in adolescents and have become more prevalent in recent decades, influenced by modern culture.
This document summarizes potential genetic disorders in Shih Tzu dogs. It notes that Shih Tzus are prone to 19 different health concerns, with eye disorders being very common. Specific eye disorders mentioned include exposure keratopathy syndrome, retinal dysplasia, cataracts, keratoconjunctivitis sicca (dry eye), entropion, progressive retinal atrophy, ectropion, and eyelash abnormalities. Other common issues include heart disorders like tricuspid valve dysplasia, cleft lip/palate, intervertebral disk disease, hydrocephalus, dermoid sinus, sebaceous adenitis, familial kidney disease, brachycephalic syndrome, and urolith
Systemic lupus erythematosus (SLE) is an autoimmune disease that causes inflammation in various tissues of the body. It most commonly affects women of childbearing age. The immune system mistakenly attacks healthy cells and organs, causing symptoms like joint pain and skin rashes. While the exact cause is unknown, genetic and environmental factors are believed to play a role. There is no cure for SLE, but treatment aims to reduce inflammation and manage symptoms. Medications may include steroids, anti-malarials, chemotherapy, and immunosuppressants. With proper treatment, many people can lead normal lives despite having SLE.
This document discusses several genetic disorders that commonly affect Maltese dogs, including heart disorders like patent ductus arteriosus and mitral valve dysplasia, eye disorders such as retinal dysplasia and glaucoma, liver disorders like portosystemic shunts, skin disorders like sebaceous adenitis, and nervous system issues including hydrocephalus, shaker dog disease, and deafness. It emphasizes that patent ductus arteriosus is very common in the breed and stresses the importance of being aware of these health risks when choosing a Maltese puppy.
The document discusses chickenpox and Down's syndrome. Chickenpox is caused by the varicella-zoster virus and spreads through saliva or mucus. It causes a red, itchy rash and symptoms include fever, headache and sore throat. Treatment involves antiviral medication or creams to reduce itchiness. Prevention includes vaccination which is highly effective. Down's syndrome is a genetic disorder caused by a third copy of chromosome 21, leading to distinctive physical features. It cannot be prevented but conditions can be treated through surgery or medication.
Measles is a highly infectious viral illness that spreads through coughing, sneezing, or direct contact with infected mucus. It causes a high fever and red blotchy rash. Complications can include ear infections, pneumonia, and rarely encephalitis. There is no specific treatment, though vitamin A and fluids can help recovery. Measles is preventable through routine MMR vaccination in childhood.
This document provides guidance on evaluating and managing patients presenting with pruritus (itching). It outlines a comprehensive approach, including performing a thorough history and physical exam to identify potential underlying causes of pruritus. Common dermatologic and systemic etiologies are described. Initial testing and workup is recommended based on identifiable skin lesions, exam findings, and risk factors identified in the history. Both pharmacologic and non-pharmacologic treatment options are presented. Sample case scenarios are also provided to demonstrate how the outlined approach would be applied in clinical practice.
This document provides a summary of rubella in 3 sentences:
Rubella, also known as German measles, is a mild viral infection usually affecting children under 10 years old. While the illness is usually mild, rubella infection during pregnancy can cause serious birth defects in the fetus known as congenital rubella syndrome. The rubella virus is transmitted through respiratory droplets and causes a rash and mild fever.
1. The patient is exhibiting signs and symptoms consistent with Kawasaki disease, including prolonged fever, oral ulcers, conjunctivitis, rash, lymphadenopathy, and extremity changes.
2. Kawasaki disease does occur in Egypt, with an estimated 280 cases diagnosed annually.
3. Treatment for Kawasaki disease involves intravenous immunoglobulin and aspirin to prevent coronary artery aneurysms, which develop in around 25% of untreated patients.
Pityriasis rosea is a common skin disease that causes an itchy rash. The rash usually appears as a single large patch called the "herald patch", followed by many smaller pink or red oval patches that spread across the torso in a characteristic pattern over 1-2 weeks. While the cause is unknown, it is possibly due to a viral infection. The rash usually disappears on its own within 6-8 weeks without treatment, though antihistamines or topical steroids can help reduce itching.
Update on infantile hemangioma part 1 Journal clup prepared by Ahmed Rashed.pptxdrahmed rashed20
summary for Update on infantile hemangioma
Vascular anomalies class -Epidemiology of Infantile Hemangioma -Pathogenesis of High-risk group infantile hemangiomas
High-risk infantile hemangiomas-Subglottic hemangiomas
Update on infantile hemangioma part 1 Journal clup prepared by Ahmed Rashed.pptxdrahmed rashed20
summary for Update on infantile hemangioma
Vascular anomalies class -Epidemiology of Infantile Hemangioma -Pathogenesis of High-risk group infantile hemangiomas
High-risk infantile hemangiomas-Subglottic hemangiomas
Approach to Cafe au lait spots in childrenVarsha Shah
This document provides guidance on evaluating and monitoring children with neurocutaneous syndromes and café au lait spots. It discusses several neurocutaneous disorders including neurofibromatosis types 1 and 2, tuberous sclerosis, ataxia telangiectasia, and others. For children presenting with café au lait spots, the provider should consider neurofibromatosis type 1 and monitor for diagnostic criteria such as additional café au lait spots, skinfold freckling, neurofibromas, Lisch nodules, and skeletal or ocular abnormalities. Regular examinations are recommended to monitor for signs of NF1 and potential complications.
Birth defects are abnormalities present at birth that can cause disabilities or death. They range from minor to serious and affect about 150,000 babies born in the US each year. Common birth defects include spina bifida, caused by inadequate folic acid during early pregnancy and clubfoot. Spina bifida occurs when the bones of the spinal column do not fully close, leaving an opening. Early prenatal surgery may help repair some birth defects. Fetal alcohol syndrome, caused by drinking during pregnancy, can result in physical deformities and neurological issues. Cerebral palsy is caused by brain injury before or during birth and results in difficulties with movement and posture. Down syndrome, caused by an extra 21st chromosome, leads to intellectual
Genetic Disorders of the Airedale TerrierLee McTaggart
This document summarizes common genetic disorders in Airedale Terriers, including musculoskeletal disorders like hip dysplasia, eye disorders like retinal dysplasia and progressive retinal atrophy, blood disorders like von Willebrand's disease, cardiovascular disorders like pulmonic stenosis, endocrine disorders like hypothyroidism, nervous system disorders like cerebellar abiotrophy, and notes that hip dysplasia is very common in the breed. It emphasizes the importance of being aware of potential health issues when choosing a dog breed and working with a reputable breeder.
This document summarizes several common genetic disorders in Lhasa Apsos, including eye disorders like cataracts, corneal dystrophy, and progressive retinal atrophy that can cause blindness. It also discusses immune disorders like atopy that cause intense itching, musculoskeletal issues like intervertebral disc disease in the back, and nervous system conditions like hydrocephalus and lissencephaly that cause seizures. Respiratory brachycephalic syndrome due to short facial structure and urinary disorders like kidney disease and urolithiasis are also covered. The document aims to inform owners of the potential health concerns for the breed.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Hiranandani Hospital in Powai, Mumbai, is a premier healthcare institution that has been serving the community with exceptional medical care since its establishment. As a part of the renowned Hiranandani Group, the hospital is committed to delivering world-class healthcare services across a wide range of specialties, including kidney transplantation. With its state-of-the-art facilities, advanced medical technology, and a team of highly skilled healthcare professionals, Hiranandani Hospital has earned a reputation as a trusted name in the healthcare industry. The hospital's patient-centric approach, coupled with its focus on innovation and excellence, ensures that patients receive the highest standard of care in a compassionate and supportive environment.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
One health condition that is becoming more common day by day is diabetes.
According to research conducted by the National Family Health Survey of India, diabetic cases show a projection which might increase to 10.4% by 2030.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
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Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
2. Rashes in the newborn period are
common. While a comprehensive list of all
possible rashes can not be made here,
following is the list of some of the common
rashes seen in newborns in Pakistan.
3. Flaky, dry skin or yellowish crusty patches on scalp. May
also show up around ears, eyebrows, armpits, and neck
creases. Sometimes causes hair loss. Most common in
newborns. It usually clears up in the first year.
4. Small white pimples, usually on the cheeks and sometimes
on the forehead, the chin, and even the back of a newborn.
May be surrounded by reddish skin. Can be present at birth
or develop between 2 and 4 weeks of age. Best to leave it
alone and not treat with creams or medications.
5. Red, bumpy rash in diaper area that may include pus-
filled bumps. May be worse in the skin folds, with some
isolated bumps around the outside of the main rash.
Lasts more than two days and doesn't respond to regular
diaper cream. More common in children who have
recently taken antibiotics.
6. Red, puffy skin in diaper area. Rash may
be flat or raised. Causes discomfort during
diaper changes. Most common in babies
under 1 year.
7. Itchy rash that typically occurs in the creases of the
elbows or knees, as well as on the cheeks, chin, scalp,
chest, and back. Appears as dry, thickened, scaly red
skin or tiny red bumps that may ooze or crust. Most
common in families with a history of allergies or asthma.
Typically shows up in the first year of life and often is
gone by age 2, but can persist through adulthood.
8. Itchy rash that typically occurs in the creases of the
elbows or knees, as well as on the cheeks, chin, scalp,
chest, and back. Appears as dry, thickened, scaly red
skin or tiny red bumps that may ooze or crust. Most
common in families with a history of allergies or asthma.
Typically shows up in the first year of life and often is
gone by age 2, but can persist through adulthood.
9. A rash of small yellow or white bumps surrounded by red
skin. Can appear anywhere on the body. Disappears on
its own in about two weeks. Common in newborns,
usually showing up two to five days after birth.
10. Tiny white or yellow pearly bumps on the nose, chin, and
cheeks. Common in newborns. They go away without
treatment in a few weeks.
11. Karachi: With scorching heat and
suffocation there is a rise in the
incidence of skin diseases namely
miliaria rubra and fungal skin infections
in Karachi.
12. Henoch Shonlein purpura (HSP) is a form of
systemic vasculitis characterized by deposition of
IgA dominant immune complexes in the small
vessels. The triad of palpable purpuric rash on lower
extremities, abdominal or renal involvement and
arthritis is the typical presentation in this condition.
The disease primarily affects children and is less
common in adults. We report a case of a young
female who presented with classical symptoms of
HSP i.e. palpable purpura on legs, arthritis and off
and on abdominal pain.
13. Henoch Schonlein purpura (HSP) is an acute small vessel
vasculitis. It is the most common vasculitis in children with an
incidence of 15 cases/ 100,000 children per year. Males are
affected more often than females. The disease is less common
in adults. Although the cause is unknown, IgA seems to play a
central role in the pathogenesis of HSP. The clinical
manifestations are the result of widespread vasculitis due to Ig
deposition in vessel walls. The major clinical features include a
palpable purpuric rash on the lower extremities, abdominal
pain or renal involvement, and arthritis. Cutaneous purpura is
the essential element in the diagnosis of HSP. The palpable
purpura is characteristically 2 to 10mm in diameter and is
usually present on the lower extremities.2 Small petechiae
may be scattered among these lesions.
14. Arthritis is the second most common feature present in 75% of
the patients2 and mostly involves the knees and ankles.
Gastrointestinal involvement occurs in 50 to 75% of patients
and renal involvement in 40 to 50% cases.2 There are no
specific diagnostic tests available for diagnosing HSP.
Laboratory studies are useful to exclude other conditions that
may mimic HSP.3,4 In majority of the cases, the disease is
self-limited.
Recurrences do occur; however they generally subside in 4 to
6 months. Renal involvement can have chronic consequences
and the long term prognosis depends on the severity of renal
involvement.
There is no consensus on a preferred treatment. Steroids
seem to be the most commonly prescribed therapy. However,
the role of pharmacologic treatment is controversial and needs
further research.
15. This is a case of a 31 years old lady who presented
with complaints of rash on legs, off and on abdominal
pain, swelling and pain in the ankles and wrists. She
was taking steroids when she presented to us. Her
past history revealed similar rash on legs about a year
before this episode and she received topical steroids
after which the rash disappeared. On examination, she
was found to have palpable purpuric rash on the lower
limbs.
Her laboratory work up revealed normal platelet count,
coagulation studies, ASO titer, renal function and ANA
profile. Based on the clinical history and normal
laboratory investigations, a clinical diagnosis of HSP
was made.
Steroids were gradually tapered and her symptoms
resolved with time.