Down syndrome is the most common cause of developmental disability in newborns, occurring due to the presence of an extra chromosome. It affects 1 in 800 live births and the risk increases with the age of the mother. Symptoms include a flat nose, small mouth, slanting eyes, as well as adverse effects on hearing and sight like frequent ear infections leading to hearing loss requiring aids. While there is no prevention or cure, screening and diagnostic tests can determine the risk and manage symptoms through regular checkups and medication. Support is available through organizations providing information, love, structure and community.