This document discusses superbugs and efforts to address the growing threat. It defines a superbug as a bacterium that has developed resistance to antibiotics used to treat it, such as MRSA. The document notes that superbugs could kill 10 million people per year and that drug companies need $25 billion to fight the crisis. It also discusses some potential treatments, including a 1,000-year-old Anglo-Saxon eye infection remedy that has shown effectiveness against MRSA, as well as efforts to design smarter antibiotic drugs that can overcome bacterial resistance mechanisms. The document is authored by Prajith.V, a first year PharmD student.

1. Prajith.V
First year PharmD @Sri Ramakrishna Institute of
Paramedical Sciences
Prajithkanna@gmail.com

2. Evolution 0f a SuperBug

3. Definition of Superbug
 An informal term for a bacterium that has become
resistant to antibiotics usually used to treat it, as
methicillin-resistant Staphylococcus aureus (MRSA) or
any multiresistant bacterium.
 "A drug-resistant superbug that spreads by skin
contact is infecting thousands of people across the US
and may now have reached Europe."

4. Prajith

5. How to Stop Superbugs..?

7. Superbugs could kill 10 million people a YEAR
 Drugs companies need up to £25billion to fight the growing
superbugs crisis, a Government advisor warns today.
 Some 41 new antibiotics are currently in development, but Mr
O’Neill said most of these do not target the most urgent needs
and will probably never see the light of day.

9. By
Prajith

10. NDM-1

12. Ancient Treatment For Eye Infections Could Be Cure
For Superbugs
 A one thousand year old Anglo-Saxon remedy for eye infections which
originates from a manuscript in the British Library has been found to kill
the modern-day superbug MRSA in an unusual research collaboration at
The University of Nottingham.

14. Designing smarter drugs to fight antibiotic resistance
Antibiotics (orange dots) face a number of potential obstacles on
their way from the site of administration to their target within the
infecting bacteria.

15. Approved antibiotics work by inhibiting a limited repertoire of bacterial targets, disrupting
essential functions such as cell wall synthesis, protein production and DNA replication.
http://www.elsevier.com

16. By

17. The Hindu
By

22. V.PRAJITH
9952253366
prajithkanna@gmail.com