This study evaluated the mechanical strength of empty aluminum tubes and aluminum tubes filled with various polymers under quasi-static loading conditions, both experimentally and using finite element analysis. Tubes made of aluminum 6063-T6 were tested when empty as well as when filled with polymers including polyurethane, polyester, vinyl ester, polyurethane foam, and silicone rubber. Experimental testing was conducted using a universal testing machine and the mechanical properties of each tube configuration were measured. Finite element modeling and analysis was also performed using ANSYS Autodyn software. The results found that polyurethane shore A70 filled aluminum tubes absorbed more energy than empty aluminum tubes and could better guide the design of crashworthy vehicle structures.