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EPIDURAL,CAUDAL &
PARAVERTEBRAL BLOCK
DR.ARNAB PATRA
DR.SOURAV DE
DR.SOUGATA ROY
History ofEpidural Anaesthesia
2
⚫ Fidel Pages first used Epidural anaesthesia in human in
1921.
⚫ T
uohy introduced the needle used in Epidural
Anaesthesia in 1945 .
⚫ Manuel Martinez used the T
uohy needle with a silk
ureteral catheter to provide continuous segmental
lumbar “peridural”anesthesia.
Anatomy
⚫ The epidural space is the
potential space between
ligamentum flavum and dura
inside the bony spinal canal
⚫ It extends from the base of
the skull to the sacral hiatus,
and surrounds the dura
mater anteriorly
,laterally
,and
posteriorly.
⚫ It comprises of anterior and
posterior epidural spaces.
3
Boundaries
⚫ Craniallyby foramen
magnum.
⚫ Caudally by
sacrococcygeal ligament.
(sacral hiatus)
⚫ Anteriorly by posterior
• longitudinal ligament
⚫ Laterallyby vertebral
pedicles & intervertebral
foramina.
⚫ Posteriorly by ligamentum
• flavum & vertebral lamina.
4
Contents
⚫Nerve roots
⚫Blood vessels-
Batson’s venous
plexus
⚫Lymphatics
⚫Fat
⚫Areolar tissue
5
Anatomic Landmarks to IdentifyVertebral Levels Before Epidural Injection
Anatomic Landmark Features
C7
Vertebral prominence,the
most prominentprocess in
the neck
T3 Root of the spine of the scapula
T7 Inferior angle of the scapula
L4 Line connecting iliac crests
S2
Line connectingthe posterior inferior
iliac spines
Sacral hiatus
Groove or depression just above
or between the glutealcleftsabove
the coccyx
6
Characteristics of Ligamentum Flavum at DifferentVertebral Levels
Site
Skin to Ligament
(cm)
Thickness of
Ligament (mm)
Cervical – 1.5–3.0
Thoracic – 3.0–5.0
Lumbar 3.0–8.0 5.0–6.0
Caudal Variable 2.0–6.0
Data used,withpermission, fromBrownDL:Spinal,epidural,caudalanesthesia.In MillerRD (ed):
Anesthesia, 6th ed. Churchill Livingstone,2005, pp 1657.
Epidural anesthesia
7
⚫Form of regional anesthesiainvolving
injection ofdrugs into the epidural space.
⚫It can be performed as a single shot
techniqueor a catheter can be placed for
either bolus dosing or continuous infusion.
Indications
8
⚫ Epidural anaesthesiawith or without sedation has been
used as the sole anaesthetic or as an adjunct to general
anaesthesia (reduces patient’srequirement for opioid
analgesics)
⚫ Orthopaedic surgery :Major hip/kneesurgery,pelvic
fractures
⚫ Obstetrics:Caesarean section,labour analgesia
⚫ Gynaecologic surgery :Procedures involvingfemale
pelvicorgans
⚫ Urologic surgery :Prostate,bladder procedures
⚫ General surgery :Upper and lower abdominal
procedures
⚫ Paediatric procedures :Penile procedures,inguinalhernia
repair
, analsurgery, orthopaedic procedures on the feet;
supplementto GA,postoperative pain relief.
⚫ Vascular surgery :Vascular reconstruction of the
lower limb vessels, amputations involving the lower
extremities.
⚫ Thoracic surgery :Postoperative analgesia,
combinationwith GA to reduce GA requirements.
⚫ Diagnosis and managementof chronic pain :
Chronic benign pain- Cervical & lumbar
radiculopathy
,vertebralcompression fracture ,
degenerativedisc disease,peripheralneuropathy
,
low back pain,pelvic pain syndrome.
⚫ Cancer related pain- pain secondary to face,neck,
shoulder, genital, pelvic, perineal etc .malignancy
.&
chemotherapyrelated peripheral neuropathy.
9
Contraindications
10
⚫Patient refusal
⚫Infection at site
⚫Raised ICP
⚫SevereAS, severe MS
⚫Allergy to LA drugs
⚫Severe hypovolaemia/shock
⚫Coagulation disorder
⚫Pre-existing neurological disease
⚫Demyelinating disease(Multiple sclerosis)
⚫Abnormalities of spine
⚫Uncooperative patient
Advantages
11
 Epidural blockade is becoming one of the most useful and
versatile procedures in modern anesthesiology.It is uniquein
that it can be placedat virtually any levelof the spine,
allowingmore flexibilityin its applicationto clinicalpractice.
 Minimal effectof surgery on Cardiopulmonaryreserve
compared to GA
 In pt.with compromised Respiratorysystem
 Morbid obesity
 COPD
 Elderly
 Earlier mobilization
 Decreased chancesof DVT
 It can be used to supplementGA, decreasingthe need for
deep levels of GA,therefore providinga more
hemodynamicallystable operative course.
Thoracic epidural analgesia has been shown to
decrease the incidence of myocardial infarction,
postoperative pulmonary complications and to
promote the return of gastrointestinal motility
without compromising fresh suture lines in the GI
tract.
Effective postoperative analgesia without taking
systemic opioids (analgesics are given through
epidural catheter)-rapid recovery
Neuroendocrine stress response to surgery is
decreased.
Blood loss is less.
12
Disadvantages
13
⚫Risk of block failure /patchy block
⚫Onset is slower
⚫Risk of introducing infection
⚫Epidural hematoma
⚫Continuous epidural catheter should not
be used in the ward ifmonitoring is not
proper.
⚫Risk ofdural puncture with 18-guage
needle
Epiduralneedle
typically sized 16-19 guage
straight tip
CRAW FORD
HUSTEAD
TUOHY
curved tip
The curved Huber tip is designed to prevent
accidental dural puncture and to facilitate passage
ofthe epidural catheter 14
EpiduralCatheter
15
⚫The catheter has
depth markings on it
so that the length of
catheter in the
epidural space can be
estimated.
⚫Multiport(3 lateral
ports) and uniport /
distalport (single end
hole) are available
Pharmacology related to EpiduralAnesthesia
16
Comparative Onset time & analgesic duration of local
anaesthetic administered epidurally 20-30 ml volume.
Drug Conc Onset(min) Duration
Plain
Duration
with
Epinephrine
Lidocaine 2% 15 80-120 120-180
Bupivacaine 0.5-0.75% 20 165-225 180-240
Ropivacaine 0.75%-1% 15-20 140-180 150-200
Mepivacaine 2% 15 90-140 140-200
Segmental Levelfor Epidural Block forVarious Surgeries
Function
Type of Surgery
(example)
Suggested Level of Entry
Surgical
anesthesi
a
Hip surgery
Lower extremity
surgery
Cesarean section
L2-3 or L3-4 interspace
Adjunct to
general
anesthesia &
Postoperativ
e analgesia
Lower abdominal
surgery
Upper abdominal
surgery
Thoracic surgery
Catheter should be placed at the midpoint of the surgical
incision for thoracic or upper abdominal surgery, lumbar
region for lower abdomen/Lower limb surgery
17
SomeCommon ProceduralPreferences
Labour
analgesia
LUCS Hip/Knee
surgery
Laparoto
my under
GA
Thoracotomy/
fractured ribs
Level of
insertion
L2-L4 L2-L4 L2-L4 T8-T10 At relevant
interspace
usally
Height of
block
T8-T9 T6-T7 T10 Upper
abdo.T7-
T8,Lower
abdo.T10
Relevant area
Density
of block
Sensory
&
Minimal
motor
Motor&
Sensory
Motor&
Sensory
Sensory
&
Minimal
Motor
Sensory&
minimal
motor
18
Labour
Analgesia
LSCS Hip/Knee
surgery
Laparotomy
under GA
Thoracotomy
/
Fractured ribs
Choice of
local
anaesthetic
0.1%-0.25%
Bupivacaine
Lignocaine2
% +
Bupivacaine
0.5%
Bupivacaine
0.5%
0.25%-
0.5%
Bupivacain
in theatre
0.25%-0.5%
Bupivacaine
in theatre or
establish
block
Infusion Bupivacaine.
1%+
Fentanyl
2mcg/ml
Post op
Bupivacaine
0.166%+Dia
morphine
.1mg/ml
Not usually
necessary
Post op
Bupivacain
0.166%+Di
amorphine
0.1mg/ml
Post op
Bupivacaine
0.166%+Dia
morphine
.1mg/ml
Rate of
infusion
0-12 ml/hr 0-8mls/hr -- 0-12mls/hr 0-8mls/hr
19
Pre operative preparation
20
⚫ Intravenous access with a catheter large enough to
administer fluids or emergency drugs should be in
place (i.e.,18- to 20-gauge).
⚫ Reversible conditions such as severe hypovolemia
should be managed prior to block placement.
⚫ Drugs and equipmentfor life support,including
airway management,must be readily available
⚫ Sedatingthe patientwith a benzodiazepineor a
narcotic allows the clinician to safely place the
epiduralblock.(Exception:pregnantmothers for
labour and delivery or caesarian section).
⚫ Monitoring blood pressure and pulse oximetry are
a minimumrequirement.
Performing theprocedure
21
 Position of patient- Careful attention to the patient’
s
position is essential to successful placement ofthe
epidural needle and catheter
.
Depending on the patient’
s medical status,weight,and
ability to cooperate,the sitting or lateral decubitus
position can be used.
Easier in sitting position.
 Approach - Four common approaches to the epidural
space are possible:
1. Midline,
2. Paramedian,
3. T
aylor (modified paramedian),
4. Caudal
⚫ Needle angulation requiredtoaccomplishepiduralblockadein
the high thoracic/low thoracic/lum
bar regions.
A: High thoracic region.B: Low thoracic region.C: Lumbar region.
22
LocatingtheEpiduralspace
23
⚫All aseptic precaution is taken.
⚫Skin is infiltrated with local anaesthetic in to
desired space(identified).
⚫Needle is advanced slowly,feel of increase
resistance.
⚫ 3 methods are used to identify Epidural space-
Loss of resistance (to with air or fluid)
Hanging drop method
Ultrasonography /Fluoroscopy
⚫As needle reaches Epidural space Loss of
Resistance is felt /Hanging drop is sucked in.
Loss of resistance technique
24
Glass syringe (Luer-Lok syringe) is used
HangingDropT
echnique
25
26
Feedingthecatheter
27
⚫Catheter is threaded through needle after
placing in space.
⚫Needle is withdrawn over the catheter
.
⚫4-6 cms catheter remain in epidural space.
Threading more catheter may increase the
likelihood of catheter malposition.
⚫Catheter is firmly secured to skin with
surgical tape.
Epiduralcatheter placement
28
Continuous infusion
29
EpiduralDosing
30
⚫ As a general guideline,
1. 1–2 mL per segment in a lumbar epidural,
2. 0.7 mL per segment in a thoracic epidural,and
3. 3 mL per segment for a sacral/caudal epidural
is used as an initial loading dose.
⚫ T
est Dose
⚫ Incremental Dosing
⚫ Aspiration to check for blood or CSF before each
dose.
⚫ After the initial loading dose, one quarter to one third
ofthe amount can be administered 10–15 min later to
intensify the sensory block.The overall level ofthe
block will not be significantly increased with this
method.
T
estDose
⚫ The purpose of the“test dose” is to make sure that the
catheter is not in the subarachnoid, intravascular
, or
subduralspace.
⚫ The classic test dose combines 3 mL of1.5% lidocainewith
15 mcg ofepinephrine.
⚫ The intrathecal injection of 45 mg of lidocaine will
producea significantmotor block consistentwith spinal
anaesthesia.
⚫ A change in heart rate of 20% or greater is an indication
ofintravascular injection warrantingthe removal and
replacementofthe catheter
.
⚫ If the heart rate does not increase by 20% or greater
, or if
a significant motor block does not develop within 5 min of
administeringthe test dose,it is considerednegative.
⚫ False-ve ifpt is on β blocker
,false +ve in pregnancyif
coincideswith labour pain. 31
Incremental Dosing
32
⚫Its purposeis to avoid excessively high
anaesthetic levels.
⚫The loading dose should be given in 5-mL
aliquots through the catheter
,repeated at
3- to 5-min intervals,giving the clinician
time to assess the patient’
s response to
dosing.
⚫If at any time the patient demonstrates an
exaggerated response,further
incremental doses should be withheld and
the patient reassessed.
Repeat dose of LA:
3
Doses are administered before the block regresses to the
point where the patient experiences pain,the “time to
two-segment regression.” Defined as the time it takes
for the sensory block to regress by two dermatome levels.
At this point, one-third to one-half of the initial loading
dose can safely be administered to maintain the block.
Depends on the duration ofaction ofthe drug
3
Table 8. ClinicalEffectsof EpidurallyInjectedLocalAnesthetics
Drug (Concentration%)
Time toT
wo-segment
Regression (min)
RecommendedTime for "T
op-Up"
Dose fromInitialActivationof Dose
(min)
Chloroprocaine(3) 45–75 45
Lidocaine (2) 60–140 60
Mepivacaine (2) 90–160 90
Bupivacaine(0.5) 180–260 120
Ropivacaine (0.5–0.75) 180–260
120
Thoracic Epidurals - salient features
⚫ The paramedian approach is easier especiallyin the
midthoracic region.
⚫ Expectmore frequentfalse loss of resistance,especiallyif the
midlineapproach is used.
⚫ The test dose not only identifiesintravascularinjection,but
also serves as a means of identifyingplacementas a band of
anesthesiashould developin the segmentwhere the local
anestheticwas injected.
⚫ Because of the proximity to cardiac accelerator fibers,smaller
bolus doses oflocal anestheticshould be used and response
checked carefully before redosing to prevent large drops in
heart rate or blood pressure.
⚫ Remember that hypotension can occur in nearly allpatients
with a high thoracic epidural blockade.In fact,it has been said
that ifthere is no hypotension after an initial bolus in the high
thoracic epidural space,it is likelythat the epidural catheter is
not in the epidural space. 34
Factors affecting EpiduralAnaesthesia
Site of injection-
 Lumbar- spread cranially more than caudally
 Thoracic- spread evenly from site of injection
 Upper thoracic & lower cervical fibres are
comparatively resistant d/
t larger size of nerve
roots-requires larger dose of LA.
 Thoracic epidural space is smaller
,require lower
volume of drug.
 Dose- 1-2 ml /segment.
 Depends on volume & concentration of drug.
Higher conc. produces a profound motor and
sensory block,whereas low conc.a selective
sensory block. 35
Age - as pt age increases
intervertebral foramina
reduced size of
decreased epidural
space size and compliance.Decreased epidural fat
necessitates decrease of dose in elderly.
Weight - There is little correlation between
the spread of analgesia and the weight of the
patient.
In morbidly obese patients,there may be
compression of the epidural space secondarily to
increased intraabdominal pressure,creating a
higher block for a given dose of local anesthetic.
36
H eight - The correlation with height is usually
not clinically significant.
Ht.<5 ft 2 inch,reduce the dose to 1 mL per
segment to be blocked.
Bromage dosing regime - Increasing the dose of
local anaesthetic by 0.1 mL per segment for
each 2 in.over 5 ft of height.
Addition of Vasoconstrictors -
Epinephrine 5 mcg/
ml (1:200000) is most
commonly added.
 Prolongs duration of action by reducing the
vascular absorption of drug.
37
Posture-
Block Ht. - Whether the patient is sitting or in
the lateral position, there is no significant
difference in block height.This is explained by the
fact that gravity and soln.baricity are not
intimately related to block spread.
Onset,Duration & Density - slightly faster on the
dependent side when the epidural in placed with
the patient in the lateral position
Pregnancy- Increased sensitivity to regional
anesthetics leads to faster onset time.
Engorgement of Epidural veins from caval
compression leads to increased incidence of
blood vessel puncture during procedure. 38
Physiologic EffectsofEpiduralBlock
39
⚫Most physiologic effects of epidural block stem
from Autonomic Blockade due to action of LA
on autonomic nerve fibres of the spinal cord.
⚫The actions mostly pertain to either Blockage
of Sympathetic outflow or Unopposed
dominance of Parasympathetic outflow.
Cardiovascular system
 Block belowT5
⚫ Sympatheticblockade
venous return CO
venodilationin blocked segments
hypotension
⚫ The compensatory mechanismfor the decrease in mean
arterial pressurecauses
1)reflex vasoconstriction above the levelof the block
2)release in catecholaminesfrom the adrenal medulla.
 Block aboveT4 (cardiac sym fibresT1-T4)
In addition to profound hypotensionand bradycardia,high
levelofsympatheticblockadecauses
⚫ Increased CVP without an increase in stroke volume
⚫ Vasoconstriction in the head,neck,and upper limbs
⚫ Splanchnicnerve blockade with blockadeof medullary
secretion of catecholamines
⚫ Blockade of vasoconstrictiveeffecton the capacitance
vessels ofthe lower limbs 41
 Respiratory system-
 Minimal impact on Pulmonary function in normal
& healthy patient,even in case of high thoracic
block
 There is concern regarding the use of epidural
blockade in patients with severe chronic lung
disease dependent on accessory muscle function
to maintain adequate ventilation, because paralysis
of respiratory muscles and changes in bronchial
tone from epidural analgesia can occur
.
41
Effects ofThoracic EpiduralAnalgesia on ventilatory
mechanisms in pts with severe lungdisease (Gruber etal)
42
Variable BeforeTEA AfterTEA ‘p’ value
Peak
inspiratory
flow rate
(L/sec)
0.48± 0.17 0.55 ± 0.14 0.02
Peak
expiratory
flow rate
(L/sec)
0.38 ± 0.17 0.40 ± 0.09 0.78
PEEP 4.8 ± 3.6 4.7 ± 3.9 0.67
Work of
breathing
(J/Ltr)
1.5 ± 0.5 1.5 ± 0.6 0.79
Maximum
inspirator
y
pressure
81.7 ± 25.5 76.8 ± 32 0.52
Gastrointestinal system
 Lumbar segments (T5-L1) for major abdominal
surgeries
 vagal dominance leads to increased secretions,inc
peristalsis and an contracted gut
 Stable visceral perfusion prevents decrease in
intramucosal pH, post-op period epidural analgesia has a
protective effect on gastric mucosa
 Thoracic segments (T1-T5) as adjunct to GA in thoracic
/cardiac /abdominal surgeries
 Segmental sympatholysis creating an increase of
sympathetic activity in segments below the block
leading to impaired splanchnic blood flow has been a
concern.
 Nausea is a common problem (20%) – treat with
atropine 44
 Renal system-
Block both Sympathetic & Parasympathetic
fibres
Loss of control of bladder function
Urinary retention
 Endocrine system-
⚫ Abolishes stress response to surgery.
⚫ Decreased release of catecholamines,GH,
cortisol, TSH, ADH, vasopressin, renin,
angiotensin,norepinephrine
44
Complications
45
Drug Related Complications:-
⚫ When an excessive dose of local anaesthetics is injected
into the epidural space or when a moderate dose is
accidentally injected into an epidural vein, systemic
toxicity can occur
.
CNS toxicity : Symptoms – Light headedness, tinnitus,
circumoral numbness and tingling, numbness of the
tongue, and blurred vision. Signs - Muscle twitching,
confusion,tremors of the facial muscles and extremities,
and shivering.
CVS toxicity :Range from mild changes in blood
pressure and pulse to complete cardiovascular collapse.
Treatment :Supportive,directed toward maintaining the
airway
,supporting ventilation, and cardiopulmonary
resuscitation ifnecessary
.
ProcedureRelatedComplications
46
⚫Minor Back Pain :Incidence between 20 and 30%.
Self-limiting.T
reated by NSAIDS,paracetamol.
⚫Postdural Puncture Headache:Due to
inadvertent dural puncture.
TOC – Epidural blood patch.
Rapid recovery in between 90 to 95% of patients after
blood patch.
Using sterile techniques, aneedle is inserted into the
epidural space at or one interspace below the prior
level of dural puncture.15 to 20 mL ofthe patient’
s
blood (drawn aseptically) is slowly injected into the
space.Rare complication – DuralAbcess after blood
patch.
⚫Subarachnoid Injection/High or Total
Spinal :Due to inadvertent injection of epidural drug
dose in sub arachnoid space.Profound hypotension,
bradycardia,and apnea will occur
.
Unconsciousness follows as a result of the effect of
local anesthetic action on the brainstem.
Treatment includes airway support and intubation, 100%
oxygen,intravenous fluids and vasopressors to maintain
hemodynamic stability.Epinephrine should be used early
and in large enough doses.
⚫Major SubduralInjection:
Subdural space extends intracranially.
A small dose of local anesthetic can have a profound
effect.
Delayed onset by 10 to 15 min compared with a high
spinal.Treatment is similar to that of a high spinal. 47
N euraxialblockin settingofanticoagulant and
antiplateletdrugs
48
(recommended byAmerican Society ofRegional
Anesthesia)
⚫ Neuraxialblock and indwellingcatheters are safe in
patientson aspirin ,NSAID’s & cox-2 inhibitors
⚫ Discontinueclopidogrel for 7 days ,ticlopidinefor
14 days ,abciximab for 24-48 hrs ,tirofiban &
eptifibatidefor 4-8 hrs before technique.
⚫ Wait at least 12 hrs before last thromboprophylaxis
dose of LMWH and 24 hrs after last full dose
⚫ W hen LMW H is begun post-op first dose should
be withheldfor at least 24 hrs if using a twice daily
dosing regimen and 6-8 hrs ifusing once daily
dosing regimen
⚫ An indwelling epidural catheter should not be removed
until 12 hrs after the last prophylaxis dose of LMWH,
and the next dose should be administered no sooner
than 2 hrs after catheter removal
⚫ If a single daily thromboprophylaxis dose of LMWH is
administered,then indwelling catheters may be
maintained postoperatively. But the concurrent use of
twice daily or therapeutic LMWH and an indwelling
epidural catheter is not recommended.
⚫ The LMWH dose is delayed for 24 hr if the patient
experienced excessive traumaduring attempted
epidural or spinal anesthesia.
⚫ Neuraxial blocks should not be performed in patients
chronically taking warfarin unless the warfarin is
stopped and the INR is <1.5
⚫ Neuraxial catheters should be removed only when the
INR is <1.5 49
Caudal space anatomy
50
⚫ The sacrum is a large triangularly shaped bone
formed by the fusion of the five sacral vertebrae.
⚫ The sacral canal contains the cauda equina
(including the filum terminale) and the spinal
meninges.
⚫ Sacral hiatus (a bony defect) is identified in the
posterior wall of the sacral canal,due to the
failure of fusion of the laminae of S5 and partially
S4
⚫ The caudal opening of the Sacral canal is the
sacral hiatus roofed by the firm elastic membrane,
the sacrococcygeal ligament,which is an
extension of the ligamentum flavum.
51
CaudalEpiduralAnaesthesia
52
⚫ Common regional technique in infants ,neonates and
pediatric pts
⚫ For lower abdominal and genitourological procedures
⚫ In adults,it is usually reserved for procedures requiring
blockage of the sacral and lumbar nerves,epidurography,
for lysis of adhesions in patients with low back pain
with radiculopathy after spinal surgery,cancer pain-bony
mets in pelvis or chemotherapy related peripheral
neuropathy.
⚫ Positions :
 Lateraldecubitus- mainly paediatric
 Prone- mainly in adults
 Knee-chest position
⚫ Point ofEntry is the Sacral Hiatus.
⚫ T
wo ways oflocating sacral hiatus:
1.Locate the posterior superior iliac spines.A line drawn
between them becomes one side of a equilateral triangle. At
the apex of the triangleis the sacral hiatus.
2.With firm pressure, identify the coccyx with the index finger
.
As the finger moves cephalad,the first pair of bony
protuberances are the cornu,which surrounds the hiatus.
53
Procedure for Caudal block
54
⚫ Prep and drape the skin in sterilefashion.
⚫ Patientis placed in a lateral or prone position (pillow
under pelvis ifprone).
⚫ Either asmaller gauge IV catheter (18- to 23-gauge) or a
20-gaugeepiduralneedleis advanced at a 45-degreeangle
from the back with the bevelup (to avoid penetratingthe
anterior sacral wall).
⚫ A distinct“pop” or “snap”is feltwhen the needlepierces
the sacrococcygealmembrane.
⚫ The needleangle is lowered to 160 degrees (almost flat)
toward the back. It is advanced not more than 1.5 cm
(usually between5 and 7 mm) in adults and not more than
0.5 cm in children.
⚫ Aspirate for blood or CSF before injectinglocal
anesthetic.
Caudal technique
55
PARAVERTEBRAL BLOCK
•HISTORY
• Paravertebral block(PVB) was first performed in 1905 and
became a popular technique for the provision of analgesia in
the early part of twentieth century. However their use
declined over the years until a publication by EASON and
WYATT in 1979 began a renaissance.
• Since then a considerable number of good quality studies
have been published on PVB and it is now an established
regional anaesthesia technique.
ANATOMY OF THORACIC PARAVERTEBRAL SPACE
• The thoracic paravertebral space begins at T1 and extends caudally to
terminate at T12.Although PVBs can be performed in the cervical and
lumber regions,there is no direct communication between adjacent
levels in these areas.Most PVBs are therefore performed at the
thoracic level.
•BOUNDARIES
• Medial wall is formed by bodies of the vertebrae,
intervertebral disc and intervertebral foraminae.
• Anterolaterally the space is bounded by the parietal pleura
and the innermost intercostal membrane.
• Posteriorly it is bounded by the transverse processes(TPs) of
the thoracic vertebrae,head of the ribs, and the superior
costotransverse ligament.
CONTENTS OF PARAVERTEBRAL SPACE
•Spinal nerves
•White rami communicantes
•Grey rami communicantes
•The sympathetic chain
•Intercostal vessels
•Fat
INDICATIONS FOR PVB
Unilateral surgeries in
thoracoabdominal region
• Breast surgery
• Thoracic surgery
• Cholecystectomy
• Renal surgery
• Appendicectomy
• Inguinal hernia repair
Relief of acute pain
• Fractured ribs
• Liver capsule pain(trauma or
ruptured cysts)
Relief of chronic pain
• Neuropathic chest or abdominal
pain
• Complex regional pain syndrome
• Refractory angina pectoris
• Relief of cancer pain
CONTRAINDICATIONS
Absolute contraindications
• Patient refusal
• Local sepsis
• Tumours in the paravertebral
space at the level of injections
• Allergy to local anaesthetic
drugs
Relative contraindications
• Severe coagulopathy
• Severe respiratory
disease(where the patient
depends on intercostal
muscle function for
ventilation)
• Ipsilateral diaphragmatic
paresis.
• Severe spinal
deformities(kyphosis or
scoliosis)
PROCEDURE FOR PVB
POSITIONING
• If awake, the patient should be seated with the neck and back flexed.
• If performed under sedation or general anaesthesia,the patient is
turned to the lateral position with the operated side uppermost.
• A bag of saline or pillow can be placed between the patient and the
operating table surface at the level of the intended block,to open up
the spaces between adjacent TPs.
CHOOSING THE LEVEL
• If only one to four dermatomes need to be blocked, a single level PVB at
or bellow the mid-dermatomal level is usually significant.(e.g. for simple
mastectomy;T3 or T4 is an appropriate level.For open cholecystectomy
T6 or T7 should be selected)
• If spread greater than four dermatomes is required,then multiple
injections will block the area more reliably;(e.g. for mastectomy and
axillary dissection, a block from atleast T1-T6 will be required. Therefore
block should be performed at each level or at T1,T3 and T5)
ADVANTAGES OF PVB
• PVB is easier to learn and perform than thoracic epidural
anaesthesia.
• Analgesia is comparable with that provided by a thoracic
epidural, in terms of success rate and analgesic efficacy.
• PVB can be performed safely in fully anaesthetized patients.
• There is less risk of neurological complications than with
most other regional anaesthetic techniques.
• Pronounced hypotension is unusual because sympathetic
block is rarely bilateral.
• Urinary retention does not occur,unlike neuraxial technique.
• Compared with interpleural blocks,PVB analgesia is more
intense and longer lasting.Serum levels of local anaesthetic
are lower.
COMPLICATIONS
PVB is safe and complications are rare.Although some reportrd
complications include
• Hypotension
• Vascular puncture
• Pleural puncture
• Pneumothorax
62

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EPIDURAL PPT.pptx

  • 1. EPIDURAL,CAUDAL & PARAVERTEBRAL BLOCK DR.ARNAB PATRA DR.SOURAV DE DR.SOUGATA ROY
  • 2. History ofEpidural Anaesthesia 2 ⚫ Fidel Pages first used Epidural anaesthesia in human in 1921. ⚫ T uohy introduced the needle used in Epidural Anaesthesia in 1945 . ⚫ Manuel Martinez used the T uohy needle with a silk ureteral catheter to provide continuous segmental lumbar “peridural”anesthesia.
  • 3. Anatomy ⚫ The epidural space is the potential space between ligamentum flavum and dura inside the bony spinal canal ⚫ It extends from the base of the skull to the sacral hiatus, and surrounds the dura mater anteriorly ,laterally ,and posteriorly. ⚫ It comprises of anterior and posterior epidural spaces. 3
  • 4. Boundaries ⚫ Craniallyby foramen magnum. ⚫ Caudally by sacrococcygeal ligament. (sacral hiatus) ⚫ Anteriorly by posterior • longitudinal ligament ⚫ Laterallyby vertebral pedicles & intervertebral foramina. ⚫ Posteriorly by ligamentum • flavum & vertebral lamina. 4 Contents ⚫Nerve roots ⚫Blood vessels- Batson’s venous plexus ⚫Lymphatics ⚫Fat ⚫Areolar tissue
  • 5. 5 Anatomic Landmarks to IdentifyVertebral Levels Before Epidural Injection Anatomic Landmark Features C7 Vertebral prominence,the most prominentprocess in the neck T3 Root of the spine of the scapula T7 Inferior angle of the scapula L4 Line connecting iliac crests S2 Line connectingthe posterior inferior iliac spines Sacral hiatus Groove or depression just above or between the glutealcleftsabove the coccyx
  • 6. 6 Characteristics of Ligamentum Flavum at DifferentVertebral Levels Site Skin to Ligament (cm) Thickness of Ligament (mm) Cervical – 1.5–3.0 Thoracic – 3.0–5.0 Lumbar 3.0–8.0 5.0–6.0 Caudal Variable 2.0–6.0 Data used,withpermission, fromBrownDL:Spinal,epidural,caudalanesthesia.In MillerRD (ed): Anesthesia, 6th ed. Churchill Livingstone,2005, pp 1657.
  • 7. Epidural anesthesia 7 ⚫Form of regional anesthesiainvolving injection ofdrugs into the epidural space. ⚫It can be performed as a single shot techniqueor a catheter can be placed for either bolus dosing or continuous infusion.
  • 8. Indications 8 ⚫ Epidural anaesthesiawith or without sedation has been used as the sole anaesthetic or as an adjunct to general anaesthesia (reduces patient’srequirement for opioid analgesics) ⚫ Orthopaedic surgery :Major hip/kneesurgery,pelvic fractures ⚫ Obstetrics:Caesarean section,labour analgesia ⚫ Gynaecologic surgery :Procedures involvingfemale pelvicorgans ⚫ Urologic surgery :Prostate,bladder procedures ⚫ General surgery :Upper and lower abdominal procedures ⚫ Paediatric procedures :Penile procedures,inguinalhernia repair , analsurgery, orthopaedic procedures on the feet; supplementto GA,postoperative pain relief.
  • 9. ⚫ Vascular surgery :Vascular reconstruction of the lower limb vessels, amputations involving the lower extremities. ⚫ Thoracic surgery :Postoperative analgesia, combinationwith GA to reduce GA requirements. ⚫ Diagnosis and managementof chronic pain : Chronic benign pain- Cervical & lumbar radiculopathy ,vertebralcompression fracture , degenerativedisc disease,peripheralneuropathy , low back pain,pelvic pain syndrome. ⚫ Cancer related pain- pain secondary to face,neck, shoulder, genital, pelvic, perineal etc .malignancy .& chemotherapyrelated peripheral neuropathy. 9
  • 10. Contraindications 10 ⚫Patient refusal ⚫Infection at site ⚫Raised ICP ⚫SevereAS, severe MS ⚫Allergy to LA drugs ⚫Severe hypovolaemia/shock ⚫Coagulation disorder ⚫Pre-existing neurological disease ⚫Demyelinating disease(Multiple sclerosis) ⚫Abnormalities of spine ⚫Uncooperative patient
  • 11. Advantages 11  Epidural blockade is becoming one of the most useful and versatile procedures in modern anesthesiology.It is uniquein that it can be placedat virtually any levelof the spine, allowingmore flexibilityin its applicationto clinicalpractice.  Minimal effectof surgery on Cardiopulmonaryreserve compared to GA  In pt.with compromised Respiratorysystem  Morbid obesity  COPD  Elderly  Earlier mobilization  Decreased chancesof DVT  It can be used to supplementGA, decreasingthe need for deep levels of GA,therefore providinga more hemodynamicallystable operative course.
  • 12. Thoracic epidural analgesia has been shown to decrease the incidence of myocardial infarction, postoperative pulmonary complications and to promote the return of gastrointestinal motility without compromising fresh suture lines in the GI tract. Effective postoperative analgesia without taking systemic opioids (analgesics are given through epidural catheter)-rapid recovery Neuroendocrine stress response to surgery is decreased. Blood loss is less. 12
  • 13. Disadvantages 13 ⚫Risk of block failure /patchy block ⚫Onset is slower ⚫Risk of introducing infection ⚫Epidural hematoma ⚫Continuous epidural catheter should not be used in the ward ifmonitoring is not proper. ⚫Risk ofdural puncture with 18-guage needle
  • 14. Epiduralneedle typically sized 16-19 guage straight tip CRAW FORD HUSTEAD TUOHY curved tip The curved Huber tip is designed to prevent accidental dural puncture and to facilitate passage ofthe epidural catheter 14
  • 15. EpiduralCatheter 15 ⚫The catheter has depth markings on it so that the length of catheter in the epidural space can be estimated. ⚫Multiport(3 lateral ports) and uniport / distalport (single end hole) are available
  • 16. Pharmacology related to EpiduralAnesthesia 16 Comparative Onset time & analgesic duration of local anaesthetic administered epidurally 20-30 ml volume. Drug Conc Onset(min) Duration Plain Duration with Epinephrine Lidocaine 2% 15 80-120 120-180 Bupivacaine 0.5-0.75% 20 165-225 180-240 Ropivacaine 0.75%-1% 15-20 140-180 150-200 Mepivacaine 2% 15 90-140 140-200
  • 17. Segmental Levelfor Epidural Block forVarious Surgeries Function Type of Surgery (example) Suggested Level of Entry Surgical anesthesi a Hip surgery Lower extremity surgery Cesarean section L2-3 or L3-4 interspace Adjunct to general anesthesia & Postoperativ e analgesia Lower abdominal surgery Upper abdominal surgery Thoracic surgery Catheter should be placed at the midpoint of the surgical incision for thoracic or upper abdominal surgery, lumbar region for lower abdomen/Lower limb surgery 17
  • 18. SomeCommon ProceduralPreferences Labour analgesia LUCS Hip/Knee surgery Laparoto my under GA Thoracotomy/ fractured ribs Level of insertion L2-L4 L2-L4 L2-L4 T8-T10 At relevant interspace usally Height of block T8-T9 T6-T7 T10 Upper abdo.T7- T8,Lower abdo.T10 Relevant area Density of block Sensory & Minimal motor Motor& Sensory Motor& Sensory Sensory & Minimal Motor Sensory& minimal motor 18
  • 19. Labour Analgesia LSCS Hip/Knee surgery Laparotomy under GA Thoracotomy / Fractured ribs Choice of local anaesthetic 0.1%-0.25% Bupivacaine Lignocaine2 % + Bupivacaine 0.5% Bupivacaine 0.5% 0.25%- 0.5% Bupivacain in theatre 0.25%-0.5% Bupivacaine in theatre or establish block Infusion Bupivacaine. 1%+ Fentanyl 2mcg/ml Post op Bupivacaine 0.166%+Dia morphine .1mg/ml Not usually necessary Post op Bupivacain 0.166%+Di amorphine 0.1mg/ml Post op Bupivacaine 0.166%+Dia morphine .1mg/ml Rate of infusion 0-12 ml/hr 0-8mls/hr -- 0-12mls/hr 0-8mls/hr 19
  • 20. Pre operative preparation 20 ⚫ Intravenous access with a catheter large enough to administer fluids or emergency drugs should be in place (i.e.,18- to 20-gauge). ⚫ Reversible conditions such as severe hypovolemia should be managed prior to block placement. ⚫ Drugs and equipmentfor life support,including airway management,must be readily available ⚫ Sedatingthe patientwith a benzodiazepineor a narcotic allows the clinician to safely place the epiduralblock.(Exception:pregnantmothers for labour and delivery or caesarian section). ⚫ Monitoring blood pressure and pulse oximetry are a minimumrequirement.
  • 21. Performing theprocedure 21  Position of patient- Careful attention to the patient’ s position is essential to successful placement ofthe epidural needle and catheter . Depending on the patient’ s medical status,weight,and ability to cooperate,the sitting or lateral decubitus position can be used. Easier in sitting position.  Approach - Four common approaches to the epidural space are possible: 1. Midline, 2. Paramedian, 3. T aylor (modified paramedian), 4. Caudal
  • 22. ⚫ Needle angulation requiredtoaccomplishepiduralblockadein the high thoracic/low thoracic/lum bar regions. A: High thoracic region.B: Low thoracic region.C: Lumbar region. 22
  • 23. LocatingtheEpiduralspace 23 ⚫All aseptic precaution is taken. ⚫Skin is infiltrated with local anaesthetic in to desired space(identified). ⚫Needle is advanced slowly,feel of increase resistance. ⚫ 3 methods are used to identify Epidural space- Loss of resistance (to with air or fluid) Hanging drop method Ultrasonography /Fluoroscopy ⚫As needle reaches Epidural space Loss of Resistance is felt /Hanging drop is sucked in.
  • 24. Loss of resistance technique 24 Glass syringe (Luer-Lok syringe) is used
  • 26. 26
  • 27. Feedingthecatheter 27 ⚫Catheter is threaded through needle after placing in space. ⚫Needle is withdrawn over the catheter . ⚫4-6 cms catheter remain in epidural space. Threading more catheter may increase the likelihood of catheter malposition. ⚫Catheter is firmly secured to skin with surgical tape.
  • 30. EpiduralDosing 30 ⚫ As a general guideline, 1. 1–2 mL per segment in a lumbar epidural, 2. 0.7 mL per segment in a thoracic epidural,and 3. 3 mL per segment for a sacral/caudal epidural is used as an initial loading dose. ⚫ T est Dose ⚫ Incremental Dosing ⚫ Aspiration to check for blood or CSF before each dose. ⚫ After the initial loading dose, one quarter to one third ofthe amount can be administered 10–15 min later to intensify the sensory block.The overall level ofthe block will not be significantly increased with this method.
  • 31. T estDose ⚫ The purpose of the“test dose” is to make sure that the catheter is not in the subarachnoid, intravascular , or subduralspace. ⚫ The classic test dose combines 3 mL of1.5% lidocainewith 15 mcg ofepinephrine. ⚫ The intrathecal injection of 45 mg of lidocaine will producea significantmotor block consistentwith spinal anaesthesia. ⚫ A change in heart rate of 20% or greater is an indication ofintravascular injection warrantingthe removal and replacementofthe catheter . ⚫ If the heart rate does not increase by 20% or greater , or if a significant motor block does not develop within 5 min of administeringthe test dose,it is considerednegative. ⚫ False-ve ifpt is on β blocker ,false +ve in pregnancyif coincideswith labour pain. 31
  • 32. Incremental Dosing 32 ⚫Its purposeis to avoid excessively high anaesthetic levels. ⚫The loading dose should be given in 5-mL aliquots through the catheter ,repeated at 3- to 5-min intervals,giving the clinician time to assess the patient’ s response to dosing. ⚫If at any time the patient demonstrates an exaggerated response,further incremental doses should be withheld and the patient reassessed.
  • 33. Repeat dose of LA: 3 Doses are administered before the block regresses to the point where the patient experiences pain,the “time to two-segment regression.” Defined as the time it takes for the sensory block to regress by two dermatome levels. At this point, one-third to one-half of the initial loading dose can safely be administered to maintain the block. Depends on the duration ofaction ofthe drug 3 Table 8. ClinicalEffectsof EpidurallyInjectedLocalAnesthetics Drug (Concentration%) Time toT wo-segment Regression (min) RecommendedTime for "T op-Up" Dose fromInitialActivationof Dose (min) Chloroprocaine(3) 45–75 45 Lidocaine (2) 60–140 60 Mepivacaine (2) 90–160 90 Bupivacaine(0.5) 180–260 120 Ropivacaine (0.5–0.75) 180–260 120
  • 34. Thoracic Epidurals - salient features ⚫ The paramedian approach is easier especiallyin the midthoracic region. ⚫ Expectmore frequentfalse loss of resistance,especiallyif the midlineapproach is used. ⚫ The test dose not only identifiesintravascularinjection,but also serves as a means of identifyingplacementas a band of anesthesiashould developin the segmentwhere the local anestheticwas injected. ⚫ Because of the proximity to cardiac accelerator fibers,smaller bolus doses oflocal anestheticshould be used and response checked carefully before redosing to prevent large drops in heart rate or blood pressure. ⚫ Remember that hypotension can occur in nearly allpatients with a high thoracic epidural blockade.In fact,it has been said that ifthere is no hypotension after an initial bolus in the high thoracic epidural space,it is likelythat the epidural catheter is not in the epidural space. 34
  • 35. Factors affecting EpiduralAnaesthesia Site of injection-  Lumbar- spread cranially more than caudally  Thoracic- spread evenly from site of injection  Upper thoracic & lower cervical fibres are comparatively resistant d/ t larger size of nerve roots-requires larger dose of LA.  Thoracic epidural space is smaller ,require lower volume of drug.  Dose- 1-2 ml /segment.  Depends on volume & concentration of drug. Higher conc. produces a profound motor and sensory block,whereas low conc.a selective sensory block. 35
  • 36. Age - as pt age increases intervertebral foramina reduced size of decreased epidural space size and compliance.Decreased epidural fat necessitates decrease of dose in elderly. Weight - There is little correlation between the spread of analgesia and the weight of the patient. In morbidly obese patients,there may be compression of the epidural space secondarily to increased intraabdominal pressure,creating a higher block for a given dose of local anesthetic. 36
  • 37. H eight - The correlation with height is usually not clinically significant. Ht.<5 ft 2 inch,reduce the dose to 1 mL per segment to be blocked. Bromage dosing regime - Increasing the dose of local anaesthetic by 0.1 mL per segment for each 2 in.over 5 ft of height. Addition of Vasoconstrictors - Epinephrine 5 mcg/ ml (1:200000) is most commonly added.  Prolongs duration of action by reducing the vascular absorption of drug. 37
  • 38. Posture- Block Ht. - Whether the patient is sitting or in the lateral position, there is no significant difference in block height.This is explained by the fact that gravity and soln.baricity are not intimately related to block spread. Onset,Duration & Density - slightly faster on the dependent side when the epidural in placed with the patient in the lateral position Pregnancy- Increased sensitivity to regional anesthetics leads to faster onset time. Engorgement of Epidural veins from caval compression leads to increased incidence of blood vessel puncture during procedure. 38
  • 39. Physiologic EffectsofEpiduralBlock 39 ⚫Most physiologic effects of epidural block stem from Autonomic Blockade due to action of LA on autonomic nerve fibres of the spinal cord. ⚫The actions mostly pertain to either Blockage of Sympathetic outflow or Unopposed dominance of Parasympathetic outflow.
  • 40. Cardiovascular system  Block belowT5 ⚫ Sympatheticblockade venous return CO venodilationin blocked segments hypotension ⚫ The compensatory mechanismfor the decrease in mean arterial pressurecauses 1)reflex vasoconstriction above the levelof the block 2)release in catecholaminesfrom the adrenal medulla.  Block aboveT4 (cardiac sym fibresT1-T4) In addition to profound hypotensionand bradycardia,high levelofsympatheticblockadecauses ⚫ Increased CVP without an increase in stroke volume ⚫ Vasoconstriction in the head,neck,and upper limbs ⚫ Splanchnicnerve blockade with blockadeof medullary secretion of catecholamines ⚫ Blockade of vasoconstrictiveeffecton the capacitance vessels ofthe lower limbs 41
  • 41.  Respiratory system-  Minimal impact on Pulmonary function in normal & healthy patient,even in case of high thoracic block  There is concern regarding the use of epidural blockade in patients with severe chronic lung disease dependent on accessory muscle function to maintain adequate ventilation, because paralysis of respiratory muscles and changes in bronchial tone from epidural analgesia can occur . 41
  • 42. Effects ofThoracic EpiduralAnalgesia on ventilatory mechanisms in pts with severe lungdisease (Gruber etal) 42 Variable BeforeTEA AfterTEA ‘p’ value Peak inspiratory flow rate (L/sec) 0.48± 0.17 0.55 ± 0.14 0.02 Peak expiratory flow rate (L/sec) 0.38 ± 0.17 0.40 ± 0.09 0.78 PEEP 4.8 ± 3.6 4.7 ± 3.9 0.67 Work of breathing (J/Ltr) 1.5 ± 0.5 1.5 ± 0.6 0.79 Maximum inspirator y pressure 81.7 ± 25.5 76.8 ± 32 0.52
  • 43. Gastrointestinal system  Lumbar segments (T5-L1) for major abdominal surgeries  vagal dominance leads to increased secretions,inc peristalsis and an contracted gut  Stable visceral perfusion prevents decrease in intramucosal pH, post-op period epidural analgesia has a protective effect on gastric mucosa  Thoracic segments (T1-T5) as adjunct to GA in thoracic /cardiac /abdominal surgeries  Segmental sympatholysis creating an increase of sympathetic activity in segments below the block leading to impaired splanchnic blood flow has been a concern.  Nausea is a common problem (20%) – treat with atropine 44
  • 44.  Renal system- Block both Sympathetic & Parasympathetic fibres Loss of control of bladder function Urinary retention  Endocrine system- ⚫ Abolishes stress response to surgery. ⚫ Decreased release of catecholamines,GH, cortisol, TSH, ADH, vasopressin, renin, angiotensin,norepinephrine 44
  • 45. Complications 45 Drug Related Complications:- ⚫ When an excessive dose of local anaesthetics is injected into the epidural space or when a moderate dose is accidentally injected into an epidural vein, systemic toxicity can occur . CNS toxicity : Symptoms – Light headedness, tinnitus, circumoral numbness and tingling, numbness of the tongue, and blurred vision. Signs - Muscle twitching, confusion,tremors of the facial muscles and extremities, and shivering. CVS toxicity :Range from mild changes in blood pressure and pulse to complete cardiovascular collapse. Treatment :Supportive,directed toward maintaining the airway ,supporting ventilation, and cardiopulmonary resuscitation ifnecessary .
  • 46. ProcedureRelatedComplications 46 ⚫Minor Back Pain :Incidence between 20 and 30%. Self-limiting.T reated by NSAIDS,paracetamol. ⚫Postdural Puncture Headache:Due to inadvertent dural puncture. TOC – Epidural blood patch. Rapid recovery in between 90 to 95% of patients after blood patch. Using sterile techniques, aneedle is inserted into the epidural space at or one interspace below the prior level of dural puncture.15 to 20 mL ofthe patient’ s blood (drawn aseptically) is slowly injected into the space.Rare complication – DuralAbcess after blood patch.
  • 47. ⚫Subarachnoid Injection/High or Total Spinal :Due to inadvertent injection of epidural drug dose in sub arachnoid space.Profound hypotension, bradycardia,and apnea will occur . Unconsciousness follows as a result of the effect of local anesthetic action on the brainstem. Treatment includes airway support and intubation, 100% oxygen,intravenous fluids and vasopressors to maintain hemodynamic stability.Epinephrine should be used early and in large enough doses. ⚫Major SubduralInjection: Subdural space extends intracranially. A small dose of local anesthetic can have a profound effect. Delayed onset by 10 to 15 min compared with a high spinal.Treatment is similar to that of a high spinal. 47
  • 48. N euraxialblockin settingofanticoagulant and antiplateletdrugs 48 (recommended byAmerican Society ofRegional Anesthesia) ⚫ Neuraxialblock and indwellingcatheters are safe in patientson aspirin ,NSAID’s & cox-2 inhibitors ⚫ Discontinueclopidogrel for 7 days ,ticlopidinefor 14 days ,abciximab for 24-48 hrs ,tirofiban & eptifibatidefor 4-8 hrs before technique. ⚫ Wait at least 12 hrs before last thromboprophylaxis dose of LMWH and 24 hrs after last full dose ⚫ W hen LMW H is begun post-op first dose should be withheldfor at least 24 hrs if using a twice daily dosing regimen and 6-8 hrs ifusing once daily dosing regimen
  • 49. ⚫ An indwelling epidural catheter should not be removed until 12 hrs after the last prophylaxis dose of LMWH, and the next dose should be administered no sooner than 2 hrs after catheter removal ⚫ If a single daily thromboprophylaxis dose of LMWH is administered,then indwelling catheters may be maintained postoperatively. But the concurrent use of twice daily or therapeutic LMWH and an indwelling epidural catheter is not recommended. ⚫ The LMWH dose is delayed for 24 hr if the patient experienced excessive traumaduring attempted epidural or spinal anesthesia. ⚫ Neuraxial blocks should not be performed in patients chronically taking warfarin unless the warfarin is stopped and the INR is <1.5 ⚫ Neuraxial catheters should be removed only when the INR is <1.5 49
  • 50. Caudal space anatomy 50 ⚫ The sacrum is a large triangularly shaped bone formed by the fusion of the five sacral vertebrae. ⚫ The sacral canal contains the cauda equina (including the filum terminale) and the spinal meninges. ⚫ Sacral hiatus (a bony defect) is identified in the posterior wall of the sacral canal,due to the failure of fusion of the laminae of S5 and partially S4 ⚫ The caudal opening of the Sacral canal is the sacral hiatus roofed by the firm elastic membrane, the sacrococcygeal ligament,which is an extension of the ligamentum flavum.
  • 51. 51
  • 52. CaudalEpiduralAnaesthesia 52 ⚫ Common regional technique in infants ,neonates and pediatric pts ⚫ For lower abdominal and genitourological procedures ⚫ In adults,it is usually reserved for procedures requiring blockage of the sacral and lumbar nerves,epidurography, for lysis of adhesions in patients with low back pain with radiculopathy after spinal surgery,cancer pain-bony mets in pelvis or chemotherapy related peripheral neuropathy. ⚫ Positions :  Lateraldecubitus- mainly paediatric  Prone- mainly in adults  Knee-chest position
  • 53. ⚫ Point ofEntry is the Sacral Hiatus. ⚫ T wo ways oflocating sacral hiatus: 1.Locate the posterior superior iliac spines.A line drawn between them becomes one side of a equilateral triangle. At the apex of the triangleis the sacral hiatus. 2.With firm pressure, identify the coccyx with the index finger . As the finger moves cephalad,the first pair of bony protuberances are the cornu,which surrounds the hiatus. 53
  • 54. Procedure for Caudal block 54 ⚫ Prep and drape the skin in sterilefashion. ⚫ Patientis placed in a lateral or prone position (pillow under pelvis ifprone). ⚫ Either asmaller gauge IV catheter (18- to 23-gauge) or a 20-gaugeepiduralneedleis advanced at a 45-degreeangle from the back with the bevelup (to avoid penetratingthe anterior sacral wall). ⚫ A distinct“pop” or “snap”is feltwhen the needlepierces the sacrococcygealmembrane. ⚫ The needleangle is lowered to 160 degrees (almost flat) toward the back. It is advanced not more than 1.5 cm (usually between5 and 7 mm) in adults and not more than 0.5 cm in children. ⚫ Aspirate for blood or CSF before injectinglocal anesthetic.
  • 56. PARAVERTEBRAL BLOCK •HISTORY • Paravertebral block(PVB) was first performed in 1905 and became a popular technique for the provision of analgesia in the early part of twentieth century. However their use declined over the years until a publication by EASON and WYATT in 1979 began a renaissance. • Since then a considerable number of good quality studies have been published on PVB and it is now an established regional anaesthesia technique.
  • 57. ANATOMY OF THORACIC PARAVERTEBRAL SPACE • The thoracic paravertebral space begins at T1 and extends caudally to terminate at T12.Although PVBs can be performed in the cervical and lumber regions,there is no direct communication between adjacent levels in these areas.Most PVBs are therefore performed at the thoracic level. •BOUNDARIES • Medial wall is formed by bodies of the vertebrae, intervertebral disc and intervertebral foraminae. • Anterolaterally the space is bounded by the parietal pleura and the innermost intercostal membrane. • Posteriorly it is bounded by the transverse processes(TPs) of the thoracic vertebrae,head of the ribs, and the superior costotransverse ligament.
  • 58. CONTENTS OF PARAVERTEBRAL SPACE •Spinal nerves •White rami communicantes •Grey rami communicantes •The sympathetic chain •Intercostal vessels •Fat
  • 59. INDICATIONS FOR PVB Unilateral surgeries in thoracoabdominal region • Breast surgery • Thoracic surgery • Cholecystectomy • Renal surgery • Appendicectomy • Inguinal hernia repair Relief of acute pain • Fractured ribs • Liver capsule pain(trauma or ruptured cysts) Relief of chronic pain • Neuropathic chest or abdominal pain • Complex regional pain syndrome • Refractory angina pectoris • Relief of cancer pain
  • 60. CONTRAINDICATIONS Absolute contraindications • Patient refusal • Local sepsis • Tumours in the paravertebral space at the level of injections • Allergy to local anaesthetic drugs Relative contraindications • Severe coagulopathy • Severe respiratory disease(where the patient depends on intercostal muscle function for ventilation) • Ipsilateral diaphragmatic paresis. • Severe spinal deformities(kyphosis or scoliosis)
  • 61. PROCEDURE FOR PVB POSITIONING • If awake, the patient should be seated with the neck and back flexed. • If performed under sedation or general anaesthesia,the patient is turned to the lateral position with the operated side uppermost. • A bag of saline or pillow can be placed between the patient and the operating table surface at the level of the intended block,to open up the spaces between adjacent TPs. CHOOSING THE LEVEL • If only one to four dermatomes need to be blocked, a single level PVB at or bellow the mid-dermatomal level is usually significant.(e.g. for simple mastectomy;T3 or T4 is an appropriate level.For open cholecystectomy T6 or T7 should be selected) • If spread greater than four dermatomes is required,then multiple injections will block the area more reliably;(e.g. for mastectomy and axillary dissection, a block from atleast T1-T6 will be required. Therefore block should be performed at each level or at T1,T3 and T5)
  • 62. ADVANTAGES OF PVB • PVB is easier to learn and perform than thoracic epidural anaesthesia. • Analgesia is comparable with that provided by a thoracic epidural, in terms of success rate and analgesic efficacy. • PVB can be performed safely in fully anaesthetized patients. • There is less risk of neurological complications than with most other regional anaesthetic techniques. • Pronounced hypotension is unusual because sympathetic block is rarely bilateral. • Urinary retention does not occur,unlike neuraxial technique. • Compared with interpleural blocks,PVB analgesia is more intense and longer lasting.Serum levels of local anaesthetic are lower.
  • 63. COMPLICATIONS PVB is safe and complications are rare.Although some reportrd complications include • Hypotension • Vascular puncture • Pleural puncture • Pneumothorax
  • 64. 62