The ethmoid bone is divided into two parts: the perpendicular plate and the horizontal plate. There are usually three turbinates - superior, middle, and inferior - that are seen on endoscopy of the nose. The middle turbinate is part of the ethmoid bone and covers several structures. The uncinate process is attached to surrounding bones and covers the maxillary hiatus along with other structures. The ethmoidal infundibulum is a funnel-shaped passage bounded by various structures that tapers posteriorly. Pneumatization from ethmoidal cells can extend to surrounding areas to form additional cells.
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Anomalies of the first and second branchial archesDr Medical
https://userupload.net/8n9v7tg9jkl1
Anomalies of the branchial arches are the second most common congenital lesions of the head and neck in children [1]. They may present as cysts, sinus tracts, fistulae or cartilaginous remnants and present with typical clinical and radiological patterns dependent on which arch is involved. The course of a particular branchial anomaly is caudal to the structures derived from the corresponding arch and dorsal to the structures that develop from the following arch. Branchial anomalies are further typed into cysts, sinuses, and fistulas.
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Anomalies of the first and second branchial archesDr Medical
https://userupload.net/8n9v7tg9jkl1
Anomalies of the branchial arches are the second most common congenital lesions of the head and neck in children [1]. They may present as cysts, sinus tracts, fistulae or cartilaginous remnants and present with typical clinical and radiological patterns dependent on which arch is involved. The course of a particular branchial anomaly is caudal to the structures derived from the corresponding arch and dorsal to the structures that develop from the following arch. Branchial anomalies are further typed into cysts, sinuses, and fistulas.
Nose is the part of respiratory system. External nose and nasal cavity. The visible portion that project from the face. It's skeleton is mainly cartilaginous ( small bony contributions are present). The superior bony part of the nose, including it's root, is covered by thin skin. Nasal septum has bony part vomer bone . Sometimes the deviation is so severe that the nasal septum is in contact with the lateral wall of the nasal cavity and often obstruct breathing or except snoring........................
Boundaries of the nasal cavity and often do I get to know about you guys are present for the nasal cavity and often do I need some of you thank god I was in my heart and soul mate is the nasal cavity and I can is wider than the roof. Inferior concha is the longest and border and is formed by an independent bone covered by
Similar to Endoscopic anatomy of ethmoid bone (20)
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
5. • turbinates are the major structures seen on endoscopy of the nose.
• passage between turbinates are called meati/ meatus.
• there are usually 3 turbinates superior, middle and inferior turbinates
with their respective meatus
• inferior turbinate is a separate bone but superior and middle
turbinate are the part of ethmoid bone.
6.
7. aggar nasi:
• most anterior part of ethmoid bone
• it is the pneumatised lacrimal bone and ethmoid crest of frontonasal
process of maxilla
• present just anterior to the attachment of middle turbinate
8.
9. agger nasi relations
• just above and anterior to middle turbinate
• anteriorly - frontal process of maxilla
• superiorly - frontal recess/ frontal sinus
• antero laterally - nasal bone
• inferomedially - uncinate process
• inferolaterally - lacrimal bone
10. middle turbinate:
• part of ethmoid bone.
• dried leaf in shape
• covers maxillary hiatus,uncinate process, bulla ethmoidalis, hiatus
semilunaris
• has curved course with passing in three planes
11. middle turbinate:
• divides into 3 segments
• basal lamella of middle turbinate
divides ethmoid labyrinth into
anterior and posterior ethmoid
air cells
12. middle turbinate attachments
• 1st part - frontonasal process of maxilla and cribriform plate
• 2nd part - lamina papyracea
• 3rd part - perpendicular plate of palatine bone
15. uncinate process
• seen after reflecting the middle
turbinate
• attached to
• lacrimal bone and frontonasal
process of maxilla anteriorly
• inferior turbinate inferiorly
• posteriorly, it is free but related to
the perperndicular plate of
palatine bone
16. • based on its superior attachment, anatomical variations of uncinate
process are noted
17. • uncinate process is one of the 4 structures that cover the maxillary
hiatus
• the other 3 include
• lacrimal bone
• inferior turbinate
• palatine bone (maxillary process)
18. bulla ethmoidalis:
• most constant anterior ethmoidal air cell
• largest ant. ethmoid cell
• attached to basal lamella of middle turbinate
• present posterior to the uncinate process
• superiorly, wall of bulla extend to skull base
19.
20.
21. hiatus semilunaris:
• sickle shaped 2 dimensional cleft
• between posterior free margin of uncinate process and anterior wall
of bulla ethmoidalis
• forms the doorway to ethmoidal infunibulum
• usually, it is referred to as hiatus semilunaris inferioris whereas,
opening of lateral sinus of grunwald is referred to as hiatus
semilunaris inferioris.( between bulla and middle turbinate)
22.
23. sinus lateralis
• seen if the posterior wall of bulla is not in contact with basal
lamella of middle turbinate
• the recess above bulla between bulla and skull base is called
suprabullar recess
• the recess behind bulla between bulla and basal lamella is
called as retrobullar recess
• together forms sinus lateralis
• boundaries are
• posteriorly - basal lamella
• anteriorly - bulla
• superiorly - skull base
• laterally - lamina papyraceae
24.
25. ethmoidal infundibulum:
• cleft like 3 dimensional space in lateral wall of nose
• funnel shaped passage
• boundaries are
• anteriorly - lacrimal bone
• posteriorly - bulla
• superiorly - frontal recess
• medially - uncinate process
• laterally - lamina papyraceae
26. • if uncinate process is attached to lamina papyracea, blind pouch is
seen superiorly in ethmoid infundibulum - called as RECESS
TERMINALIS. described by stammberger as an inverted egg cup.
• posteriorly, infundibulum tapers parallel to the tapering of uncinate
process
27.
28.
29. superior turbinate:
• 1/2 the length of middle turbinate
• starts from middle part of middle turbinate
• has opening of posterior ethmoidal cells in its meatus
31. • anterior ethmoidal artery is a branch of ophthalmic artery given in
orbit.
• enters the nose, transverses across the roof of ethmoidal sinus in an
anteromedial direction and then leaves the nose at lateral lamella of
cribriform plate to enter in to cranial cavity
• thus the canal in which it transverses is called as orbitocranial canal.
• lateral end of canal is - suture line of frontal bone and lamina
papyracea
• medial end is - cribriform plate
• canal is 17mm below the roof of ethmoid, 1-2 mm behind the point
where anterior wall of bulla meets skull base
32. • from cranial cavity, artery turns anteriorly along the cribriform plate
in a sulcus called ethmoidal sulcus (length of ethmoid sulcus - 3 to
16mm)
• then, enters the nasal cavity on either side of crista galli
33. posterior ethmoidal artery:
• branch of ophthalmic artery.
• passes through fissure between frontal bone and lamina papyracea to
enter nasal cavity
• as it lies high in roof of ethmoid, usually not seen easily
• enters cranial cavity through cribriform plate and then again passes
through foramen in cribriform plate to enter back into nasal cavity
34.
35. • anterior nasal crest to anterior ethmoid artery - 22 to 24 mm
• anterior to posterior ethmoidal artery - 12 to 15 mm
• posterior ethmoidal artery to optic canal - 3 to 7 mm( 6mm)
36. keros classification:
• the depth of olfactory fossa is classified by keros classification
• it is the height of lateral lamella of cribriform plate
• based on the height, it is of 3 types
• type 1 - 1 to 3 mm
• type 2 - 4 to 7 mm
• type 3 - 8 to 17 mm
37.
38. ethmoidal cells:
• anterior ethmoidal cells are cuboidal to round in shape
• as we go posteriorly, posterior ethmoid cells are conical in shape.
• pneumatisation from ethmoidal cells can extend to the surroundings
to form
• haller cell
• supra orbital cell
• onodi cell
• frontal sinus
• agger nasi cell