Introduction
Functions
Development
Structure
Nasal cavity
Nasal septum
Lateral wall
Applied anatomy and pathology –
- danger area of nose
- nose bleeding
- foreign body in nose
- developmental nasal deformities
- nasal polyps
- mouth breathing
- rhinitis
Introduction
Functions
Development
Structure
Nasal cavity
Nasal septum
Lateral wall
Applied anatomy and pathology –
- danger area of nose
- nose bleeding
- foreign body in nose
- developmental nasal deformities
- nasal polyps
- mouth breathing
- rhinitis
surgical anatomy of nose is a humble attempt to make the anatomy of nose simpler and easy for medical students and fellow physicians. at the end of the presentation the students will be able to identify all the structures.
surgical anatomy of nose is a humble attempt to make the anatomy of nose simpler and easy for medical students and fellow physicians. at the end of the presentation the students will be able to identify all the structures.
It contains following subheadings:
-maxilla and mandible anatomy
-TMJ(Temporo mandibular joint)
-Muscles of mastication
By:
Dr. Syed Irfan Qadeer
Prof. and HOD Department of Anatomy
SPIDMS,Lucknow
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. ETHMOID BONE
• SINGLE DELICATE BONE
• NUMEROUS AIR CELLS – ETHMOID SINUSES
• HORIZONTAL PLATE – CRIBRIFORM PLATE
• VERTICAL PLATE – PERPENDICULAR PLATE – POSTERIOR
PART OF THE SEPTUM.
3.
4. CRIBRIFORM PLATE
• Fits into the notch in the frontal bone.
• Separates the nose from anterior cranial fossa
• Perforated by many foramina – transmits – olfactory nerves ,
anterior and posterior ethmoidal arteries.
• Upper surface – midline projection – CRISTA GALLI.
6. • 2 PARTS – Horizontal medial lamella and Vertical or Oblique
lateral lamella
• Lateral lamella articulates with the frontal bone.
• Skull base – Ethmoid Fovea – medially by lateral lamella (thin
bone – 0.2mm) and laterally by frontal bone (thick bone –
0.5mm).
• Anterior ethmoidal artery piercing the dura medially – thinnest
area (0.05mm) in skull base.
8. • Ethmoid roof configuration differentiated based on the length of
the lateral lamella of cribriform plate – KEROS
CLASSIFICATION
• Type 1 – 1-3mm
• Type 2 – 4-7mm
• Type 3 – 8-17mm
9. • Posterior attachment – Horizontal plane – along lamina
papyracea and perpendicular plate of the palatine bone up to
the roof of the posterior choana.
• UNCINATE PROCESS :
• Articulates anteriorly - Lacrimal bone
• Posteriorly – Inferior turbinate and perpendicular plate of the
palatine bone.
• ETHMOID CELLS :
• Anterior and Posterior.
10. • Lateral to the perpendicular plate – two masses of air cells –
ETHMOID SINUSES.
• Bounded – Medially – Middle and Superior Turbinate
• Laterally – Paper thin lamina papyracea.
• MIDDLE TURBINATE :
• Anterior attachment – saggital plane – frontonasal process of
maxilla and cribriform plate.
• Turns laterally – coronal plane – attached to the lamina
papyracea – BASAL OR GROUND LAMELLA
12. • Anterior cells – anterior to ground lamella – open in middle
meatus.
• Posterior cells – Posterior to ground lamella – Superior meatus
or Spheno ethmoidal recess.
• The Ethmoidal Bulla – Large and Fairly constant anterior
ethmoid air cell.
• The ethmoid cells – incomplete – superiorly and posteriorly –
completed by superior by frontal bone and posteriorly by
sphenoid bone.
13. • PATHS OF PNEUMATIZATION :
• Anterosuperiorly : into frontal bone – FRONTAL SINUS
• Superiorly : above ethmoid bulla over the orbit and behind
frontal sinus – SUPRAORBITAL CELL
• Inferolaterally : Roof of the maxillary sinus – HALLER CELL
• Posteriorly : Above sphenoid sinus – ONODI CELL.
14. • Anteriorly : Lacrimal bone and frontonasal process of maxilla –
AGGER NASI CELLS
• Superiorly : Frontal recess – different types of frontal cells
• Isolated cells – within ethmoidal infundibulum – INFUNDIBULAR
CELLS.
15. ETHMOIDAL ARTERIES
• ANTERIOR ETHMOID ARTERY :
• Branch of ophthalmic artery – given off in orbit
• Enters nose, traverses across the roof of the ethmoidal sinus in
an anteromedial direction and leaves the nose at lateral lamella
of cribriform plate to enter cranial cavity.
• ORBITOCRANIAL CANAL – traverses through this canal.
• Lateral end – suture line of the frontal bone and the lamina
papyracea
17. • Medial end at cribriform plate – thinnest part of the anterior
cranial fossa.
• Oblique canal.
• Runs at a variable distance as much as 17mm below the roof of
the ethmoid.
• Attached to it by a Bony Mesentry.
• Lies 1-2mm behind the point where the anterior wall of bulla
meets skull base.
18. • If bulla does not extend to skull base, artery lies in suprabullar
recess.
• Endoscopic finding : artery is present where the vertical
posterior wall of the frontal sinus turns to form the horizontal
base skull.
• On entering the cranial cavity – turns anteriorly along the
cribriform plate in a sulcus called the ETHMOIDAL SULCUS.
• Gives off a meningeal branch.
19.
20. • Re-enters nasal cavity on either side of the crista galli.
• Passes in a groove along the inner surface of the nasal bone –
supplying upper part of the septum and lateral nasal wall.
• Appears on the external surface of the nose through a nottch
between the nasal bone and the upper lateral cartilage.
21. POSTERIOR ETHMOID ARTERY
• Arises from ophthalmic artery in the orbit.
• Passes through the fissure between the frontal bone and the
lamina papyracea 6mm in front of the optic foramen to enter
nasal cavity.
• Anteromedially – enter into cranial cavity – level of cribriform
plate.
• Traverses the cribriform plate in an anterior direction – passes in
one of its foramina to re enter the nasal cavity.