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Embryology of the Inner Ear
     First Appearances/otocysts

The inner ear first appears as a thickening
of ectoderm—the auditory placode.
In the twenty-fourth day of embryo
formation hollow cysts have formed--
otocysts (auditory vesicles)
Embryology of the Inner Ear
     First Appearances/otocysts

The otocysts soon become detached from
the ectoderm from which they arose.
At that point where the otocyst has
detached from the ectoderm, the
endolymphatic sac begins to extend in the
medial direction.
Embryology of the Inner Ear
 First Appearances/Cochlear Duct

It continues to dilate; and this slender
medial endolymphatic sac becomes the
cochlear duct.
The dorsal portion begins to show
indications of developing the semicircular
canals (for balance).
Embryology of the Inner Ear
     First Appearance/Cochlea

By the end of the seventh week, the
otocyst has been modeled roughly into the
membranous labyrinth with its semicircular
canals and a cochlea with one turn.
Embryology of the Inner Ear
  First Appearance/Cochlear Duct

In the eighth week, the endolymphatic
duct with the three semicircular canal are
well defined and utricle and saccule have
been divided.
The cochlear duct has begun to coil into
its familiar snail shell shape.
Embryology of the Inner Ear
  First Appearance/Cochlear Duct

By the third month, the adult form of the
inner ear has been nearly completed.
Its further development results in complete
separation of the utricle and saccule which
remains attached to the endolymphatic
duct by a short slender canal.
Embryology of the Inner Ear
 First Appearance/Tectorial Membrane

 With the development of the membranous
 labyrinth, the spiral organ divides into an
 inner and outer ridge.
 Both ridges become covered with an
 increasingly prominent tectorial
 membrane.
Embryology of the Inner Ear
     First Appearance/Hair Cells

In the area between these two ridges the
epithelial cells begin to form the sensory
hair cells.
Embryology of the Inner Ear
  First Appearance/Bony Labyrinth

The mesoderm surrounding the
membranous (epithelial) labyrinth
becomes differentiated into a fibrous
membrane and later into cartilage.
Embryology of the Inner Ear
     First Appearance/Perilymph

At about the tenth week, the cartilage
immediately surrounding the membranous
labyrinth undergoes a peculiar reversal of
development.
It returns to a precartilaginous condition in
which the cells lose their boundaries.
Embryology of the Inner Ear
    First Appearance/Perilymph

This loose network of cells becomes the
perilymphatic space surrounding the
membranous labyrinth.
When this has taken place, the
membranous labyrinth becomes
suspended in the fluid of the perilymphatic
spaces.
Embryology of the Inner Ear
    First Appearance/Perilymph

The perilymphatic spaces continue to
develop above and below the cochlear
duct creating the upper (scala vestibuli
area) and the lower (scala tympani area).
Embryology of the Inner Ear
  First Appearance/Bony Labyrinth

By the fifth month, the cartilage
surrounding the membranous labyrinth
has become the bony labyrinth (the
hardest bone in the human body).
Thus, by the middle of fetal life, the inner
ear has attained its full adult size.
Embryology of the Inner Ear

Now that we are aware of how the inner
ear is formed inside the womb, we can
become more aware of how the mother’s
health conditions may affect the
development of the fetus’s inner ear.
This is an area where we will work
extensively when providing hearing
“treatment” to an adult with cochlear
damage.
Embryology of the Inner Ear


Whether it is a pre-natal malformation of
the cochlea or damage in adulthood, the
inner ear is an area that we must fully
understand when applying electroacoustic
stimulation.

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HIS 120 Embryology of the Inner Ear

  • 1. Embryology of the Inner Ear  First Appearances/otocysts The inner ear first appears as a thickening of ectoderm—the auditory placode. In the twenty-fourth day of embryo formation hollow cysts have formed-- otocysts (auditory vesicles)
  • 2. Embryology of the Inner Ear  First Appearances/otocysts The otocysts soon become detached from the ectoderm from which they arose. At that point where the otocyst has detached from the ectoderm, the endolymphatic sac begins to extend in the medial direction.
  • 3. Embryology of the Inner Ear  First Appearances/Cochlear Duct It continues to dilate; and this slender medial endolymphatic sac becomes the cochlear duct. The dorsal portion begins to show indications of developing the semicircular canals (for balance).
  • 4. Embryology of the Inner Ear  First Appearance/Cochlea By the end of the seventh week, the otocyst has been modeled roughly into the membranous labyrinth with its semicircular canals and a cochlea with one turn.
  • 5. Embryology of the Inner Ear  First Appearance/Cochlear Duct In the eighth week, the endolymphatic duct with the three semicircular canal are well defined and utricle and saccule have been divided. The cochlear duct has begun to coil into its familiar snail shell shape.
  • 6. Embryology of the Inner Ear  First Appearance/Cochlear Duct By the third month, the adult form of the inner ear has been nearly completed. Its further development results in complete separation of the utricle and saccule which remains attached to the endolymphatic duct by a short slender canal.
  • 7. Embryology of the Inner Ear  First Appearance/Tectorial Membrane With the development of the membranous labyrinth, the spiral organ divides into an inner and outer ridge. Both ridges become covered with an increasingly prominent tectorial membrane.
  • 8. Embryology of the Inner Ear  First Appearance/Hair Cells In the area between these two ridges the epithelial cells begin to form the sensory hair cells.
  • 9. Embryology of the Inner Ear  First Appearance/Bony Labyrinth The mesoderm surrounding the membranous (epithelial) labyrinth becomes differentiated into a fibrous membrane and later into cartilage.
  • 10. Embryology of the Inner Ear  First Appearance/Perilymph At about the tenth week, the cartilage immediately surrounding the membranous labyrinth undergoes a peculiar reversal of development. It returns to a precartilaginous condition in which the cells lose their boundaries.
  • 11. Embryology of the Inner Ear  First Appearance/Perilymph This loose network of cells becomes the perilymphatic space surrounding the membranous labyrinth. When this has taken place, the membranous labyrinth becomes suspended in the fluid of the perilymphatic spaces.
  • 12. Embryology of the Inner Ear  First Appearance/Perilymph The perilymphatic spaces continue to develop above and below the cochlear duct creating the upper (scala vestibuli area) and the lower (scala tympani area).
  • 13. Embryology of the Inner Ear  First Appearance/Bony Labyrinth By the fifth month, the cartilage surrounding the membranous labyrinth has become the bony labyrinth (the hardest bone in the human body). Thus, by the middle of fetal life, the inner ear has attained its full adult size.
  • 14. Embryology of the Inner Ear Now that we are aware of how the inner ear is formed inside the womb, we can become more aware of how the mother’s health conditions may affect the development of the fetus’s inner ear. This is an area where we will work extensively when providing hearing “treatment” to an adult with cochlear damage.
  • 15. Embryology of the Inner Ear Whether it is a pre-natal malformation of the cochlea or damage in adulthood, the inner ear is an area that we must fully understand when applying electroacoustic stimulation.