E-commerce refers to the buying and selling of goods or services over the Internet. There are several types including business-to-business (B2B), business-to-consumer (B2C), consumer-to-consumer (C2C), and consumer-to-business (C2B). The document traces the history of e-commerce from the 1970s to today and discusses how the Internet has enabled global e-commerce opportunities and challenges. Key issues for multinational companies include understanding cultural differences that impact adoption rates, building consumer trust, and designing websites that are culturally sensitive.