This document provides information about dentifrices (substances used with a toothbrush for cleaning teeth). It discusses the history of dentifrices, types (cosmetic and therapeutic), composition, recent developments, literature reviews, and advice for patients. Dentifrices contain abrasives, detergents, flavors, sweeteners, and compounds like fluoride, triclosan, and stannous fluoride that fight plaque, tartar, and sensitivity. Recent developments include children's toothpastes and whitening pastes. Literature reviews examine the effectiveness of ingredients like triclosan and chlorhexidine at reducing plaque and gingivitis. Advice includes using small amounts of fluoride paste and mild abrasives for certain