Cerebrospinal fluid (CSF) is found in the brain and spinal cord, originating from the choroid plexus, and serves key functions including protection, buoyancy, homeostasis, waste removal, and transport of nutrients. The document also describes bacterial and viral meningitis, highlighting that bacterial meningitis is an acute infection leading to severe CNS symptoms, while viral meningitis is generally less severe and caused by various viruses. Additionally, it provides normal CSF composition details and references for further reading.

1. CEREBROSPINAL FLUID

2. CONTENTS:-
•DEFINITION
•FUNCTIONS
•COMPONENTS
•APPLIED

3. DEFINITION
• CEREBROSPINAL FLUID (CSF) is found within the
subarachoid space and ventricles of the brain as well as
around the spinal cord.
• The fluid originates from choroid plexus and returns to the
body in the vessels of the lumbar region.

4. FUNCTIONS
• CSF serves several imp functions in the CNS.
1. Protection:-CSF cushions the brain and spinal cord
providing a buffer and helping to protect them from injury.
2. Buoyancy:- It helps to support the weight of the brain
reducing the pressure on the base of the brain caused by
its own weight.
3. Homeostasis:-CSF helps to maintain a stable
environment around the brain and spinal cord by
regulating the chemical composition of the extracellular
fluid in the central nervous system.

5. 4. Waste Removal:-. CSF acts as a medium for removing
waste products from the brain and spinal cord and
eliminated by the blood stream
5. Transport:-It facilitates the transport of nutrients
hormones and other substances to and from the brain and
spinal cord
CSF plays a crucial role in maintaining the health and
proper functioning of the CNS

6. COMPONENTS

7. APPLIED
1.Bacterial
meningitis.
2.Viral meningitis.

9. Bacterial meningitis
• It is an acute purulent infection within the subarachnoid space.
• Associated with CNS inflammatory reactions resulting in
decreased consciousness seizures raised ICP and stroke
• Composition of CSF in health and diseases
Colour and appearance - Clear and colourless ,
Cell count - 0-4 X 10^6/L,
Protien Concentration - 10-30 mg/dl,
Sugar - 50-70 mg/dl,
Coagulation not seen

11. Viral meningitis
• Viral meningitis is an inflammation of the meninges, the
protective membranes covering the brain and spinal cord.
• It is caused by viruses rather than bacteria. The most
common culprits are enteroviruses, though other viruses
like herpes simplex virus (HSV), mumps virus, and
measles virus can also cause it.
• Viral meningitis is generally less severe than bacterial
meningitis.

13. References:-
1.Harrison's principles of internal medicine.
2.Davidson's.
3.DM Vasudevan.