3. DEFINITION
• CEREBROSPINAL FLUID (CSF) is found within the
subarachoid space and ventricles of the brain as well as
around the spinal cord.
• The fluid originates from choroid plexus and returns to the
body in the vessels of the lumbar region.
4. FUNCTIONS
• CSF serves several imp functions in the CNS.
1. Protection:-CSF cushions the brain and spinal cord
providing a buffer and helping to protect them from injury.
2. Buoyancy:- It helps to support the weight of the brain
reducing the pressure on the base of the brain caused by
its own weight.
3. Homeostasis:-CSF helps to maintain a stable
environment around the brain and spinal cord by
regulating the chemical composition of the extracellular
fluid in the central nervous system.
5. 4. Waste Removal:-. CSF acts as a medium for removing
waste products from the brain and spinal cord and
eliminated by the blood stream
5. Transport:-It facilitates the transport of nutrients
hormones and other substances to and from the brain and
spinal cord
CSF plays a crucial role in maintaining the health and
proper functioning of the CNS
9. Bacterial meningitis
• It is an acute purulent infection within the subarachnoid space.
• Associated with CNS inflammatory reactions resulting in
decreased consciousness seizures raised ICP and stroke
• Composition of CSF in health and diseases
Colour and appearance - Clear and colourless ,
Cell count - 0-4 X 10^6/L,
Protien Concentration - 10-30 mg/dl,
Sugar - 50-70 mg/dl,
Coagulation not seen
10.
11. Viral meningitis
• Viral meningitis is an inflammation of the meninges, the
protective membranes covering the brain and spinal cord.
• It is caused by viruses rather than bacteria. The most
common culprits are enteroviruses, though other viruses
like herpes simplex virus (HSV), mumps virus, and
measles virus can also cause it.
• Viral meningitis is generally less severe than bacterial
meningitis.