rotablation is procedure used in complex pci with heavily calcified lesion for adequate expansion of stent.if used in indicated case and well aware of contraindication is necessary for achieving good results.
Although the risks of coronary angiography have declined over the years by increased clinical experience and advanced technologies, it still requires attention, knowledge and experience due to being an interventional diagnostic method. A safe coronary angiography begins with the selection of the appropriate catheter for the anatomical structure of the patient and the evaluation of the pressure when the catheter is placed in the coronary ostium. Coronary pressure waves are complementary requirements of angiography. The recognition, evaluation and precautions to be taken for abnormal pressure waves directly affect the mortality of the patient. One of the first clues to the presence of stenosis in the left main coronary artery (LMCA) is abnormal changes in pressure when the catheter is seated in the ostial LMCA. This often occurs as a “ventricularization” or “damping”. For decades, ventricularization was mostly experienced as a stenosis by invasive cardiologists [1]. Recognition of abnormal changes in pressure and precautions to be taken prevent catastrophic outcomes in patients
https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000518.pdf
For more open access journals in Crimson Publishers
please click on https://crimsonpublishers.com/
For more articles in open journal of Cardiology & Heart Diseases
please click on https://crimsonpublishers.com/ojchd/
rotablation is procedure used in complex pci with heavily calcified lesion for adequate expansion of stent.if used in indicated case and well aware of contraindication is necessary for achieving good results.
Although the risks of coronary angiography have declined over the years by increased clinical experience and advanced technologies, it still requires attention, knowledge and experience due to being an interventional diagnostic method. A safe coronary angiography begins with the selection of the appropriate catheter for the anatomical structure of the patient and the evaluation of the pressure when the catheter is placed in the coronary ostium. Coronary pressure waves are complementary requirements of angiography. The recognition, evaluation and precautions to be taken for abnormal pressure waves directly affect the mortality of the patient. One of the first clues to the presence of stenosis in the left main coronary artery (LMCA) is abnormal changes in pressure when the catheter is seated in the ostial LMCA. This often occurs as a “ventricularization” or “damping”. For decades, ventricularization was mostly experienced as a stenosis by invasive cardiologists [1]. Recognition of abnormal changes in pressure and precautions to be taken prevent catastrophic outcomes in patients
https://crimsonpublishers.com/ojchd/fulltext/OJCHD.000518.pdf
For more open access journals in Crimson Publishers
please click on https://crimsonpublishers.com/
For more articles in open journal of Cardiology & Heart Diseases
please click on https://crimsonpublishers.com/ojchd/
An educational material describing the Indications for Tracheostomy-Complications of Tracheostomy-Timing of Tracheostomy-Tracheostomy Technique-Tracheostomy Decannulation and types of Tracheostomy Tubes.
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An educational material describing the Indications for Tracheostomy-Complications of Tracheostomy-Timing of Tracheostomy-Tracheostomy Technique-Tracheostomy Decannulation and types of Tracheostomy Tubes
This slide will provide illustrative information regarding coronary angioplasty . It also focus on practical area knowledge of cardiac catheterization which one should focus while caring patient with coronary angioplasty.
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How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
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Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
3.
Coronary artery perforation is defined as
extravasation of contrast/blood from coronary
artery, during or after PCI.
Incidence range from 0.19% to 3% with 13x increase
in hospital mortality and 5x rise in 30 day mortality
Risk of temponade is 0.3%.
INTRODUCTION
4.
Ellis and colleagues described the first series of 12900
pts from 1990 and 1991.
Incidence was 0.5%
Incidence of temponade in type I CAP was 8%
63% of type III CAP developed temponade with
mortality of 19%.
Female gender and increasing age were predisposing
patient characteristics.
INITIAL DATA
5.
Subsequent meta-analysis of 16 studies involving
197061 cases reported:
Incidence – 0.43%
Mortality and cardiac temponade incidence: type I,
0.4% and 0.35; type II, 3.3% and 0.4%; type III, 45.7%
and 21.2%, respectively
Type III were associated with high long term MACE
rates.
16.
FUKOTOMI
Type I: Epicardial staining without contrast
extravasation
Type II: Epicardial staining with a visible jet of
contrast extravasation
KINI
Type I: Myocardial staining without contrast
extravasation
Type II: Contrast extravasation into pericardium,
coronary sinus or cardiac chambers
17.
High index of suspicion
Clinical clues
Hypotension , severe chest pain, nausea, ST segment
changes, vasovagal with severe bradycardia and
hypotension
Late temponade as late as 24 hrs post PCI reported
Prognosis depends on severity of perforation as well
as other risk factors
CTO PCI, perforation is associated with a 7.1% rate
of death and 25.9% rate of major adverse cardiac
events (MACEs)
Diagnosis and prognosis
18.
GENERAL MANAGEMENT
A. BALLOON INFLATION:
1. Proximal or at perforation site immediately, should
be of same size of vessel, semi compliant and inflated
to not more than 8-10 atm.
2. Inflation is prolonged atleast 10-15 min
3. May seal small perforations on itself particularly Ellis
I/II
Management
19.
BALLOON INFLATION TYPES
1. Persistent complete occlusion
Not feasible as >20 min of total occlusion time is
unacceptable for humans
Thrombus may not be mature sufficiently to occlude the
vessel
Anticoagulant effects of heparin could not be reversed as
protamine cannot reach the perforation site
20.
2. Persistent partial occlusion
No current reports available.
Theoretically possible
MAP should be maintained at 50-65 mmhg and for
hypertensive patients MAP should be controlled at
30% below baseline
FFR <0.4, ∆P >60 mmhg; for creation of 90% stenosis.
Goal is TIMI grade 2 flow
21.
3. Intermittent complete occlusion
Most commonly used method
“Ischemic preconditioning (IPC)”; nonfatal complete
ischemia found to improve tissue tolerability to
reperfusion injury after long-term ischemia and to
delay cell death.
The protection of IPC can be divided into two time
phases: early and late.
Early IPC phase occurs within the first 2-3 hrs after an
ischemic event
22.
Late phase occurs between 12–24 hrs and 48–72 hrs.
If cardiac surgery is unavoidable for patients with
pericardial tamponade, the best time window is within
3 hrs after balloon occlusion, when the protective
effect of IPC is maximal.
A 10 min ischemia/ 1 min reperfusioin model is
optimal
May not be satisfactory in patients with cardiac
diseases
5min/5min model can be used in such patients.
4. Intermittent partial occlusion.
23.
B. SECURE ARTERIAL ACCESS
• Second access needed if guide catheter used is not 8F,
as additional bulky instrument may be needed.
C. I/V FLUIDS AND VASSOPRESSORS/ATROPINE
D. PERICARDIOCENTESIS:
Timing guided by hemodyanamics, urgent if
hemodyanamic instability,
Small effusions may be managed conservatively.
E. Notify surgical team
24.
ANTICOAGULATION REVERSAL
Should be deferred till all interventional equipments
are removed, and pericardiocentesis done .
Carries risk of stent thrombosis, pericardial blood
coagulation
ACT should be kept <150 s
Protamine 1mg/1oo units of UHF max 50mg rate
<5mg/min, is used for heparin reversal.
IIb/IIIa inhibitors should be discontinued
25.
CAUSES
Oversized stents, high pressure balloon inflations, sp
in heavily calcified arteries
Balloon ruptures
Atherectomy
Guidewire exit followed by inadvertent equipment
advancement
Large vessel perforation
26.
TREATMENT
Balloon inflation
Covered stents
Single guide: block and deliver technique
Double guide: ping pong technique
Prolonged balloon inflations if covered stents not
available
Surgery
Dissection technique
27.
COVERED STENTS
Most widely used is PTFE covered stent,(Graftmaster)
sandwich design, PTFE layer in between two BMS.
Inflexible, difficult to deliver
Bulky and require special guide techniques, excellent
support.
Require aggressive post dialatation to achieve good
expansion, > 20 atm
Side branch exclusion may cause periprocedural MI
28.
IVUS used to confirm proper deployment and
expansion
Edge dissections should be ruled out and has to be
covered with additional stents
High rate of restenosis and 22% 1 year MACE
reported with covered stents.
29.
GRAFTMASTER
Consists of two stainless steel stents with a middle
layer of ePTFE.
Bulky and difficult to deliver; hence excellent guide
catheter support is important.
Available in diameters of 2.8 to 4.8 mm and lengths
between 16 and 26 mm
Requires a 6 French guide catheter for the 2.8 to 4.0
mm stents and a 7 French guide catheter for the 4.5
and 4.8 mm stents
30.
Graftmaster Rx may be difficult to advance through
previously deployed stents, necessitating techniques
such as distal anchor and use of a guide catheter
extension
Minimum inflation pressure is 15 atm, but even higher
pressures for up to 60 seconds (and use of
intravascular ultrasound) are preferred to ensure
adequate stent expansion.
After expansion the stent may shorten up to 1.6 mm
on each side (for a total of 3.2 mm at nominal pressure,
which is 15 atm).
31.
Use of a dual catheter (“ping-pong guide”) technique
is often required,
Postdilation of the shoulders of the stent may be
necessary to fully appose the stent to the vessel wall
if extravasation persists behind the stent despite
covering the perforation.
32.
PK PAPYRUS
Covered coronary stent system is a balloon-
expandable covered stent mounted on a rapid-
exchange delivery catheter
Device size matrix ranges from 2.5 to 5.0 mm stent
diameters and lengths of 15, 20, and 26 mm
Papyrus stent may be postdilated to a maximum stent
expansion diameter of 3.50 mm for the 2.5 and 3.0 mm
stents; 4.65 mm for the 3.5 and 4.0 mm stents; and 5.63
mm for the 4.5 and 5.0 mm stents.
33.
Compatible with 5 French guiding catheters for
diameters 2.54 mm and 6 French for diameters 4.5 and
5.0 mm
Easier to deliver compared with the Graftmaster but
can occasionally be dislodged from the balloon during
attempts to deliver it to the perforation site,
39.
Difficult to diagnose, as they are small, specially
when collimation is used to reduce radiation.
Temponade may develop late, therefore require
monitoring and serial echo,
Gp Ib/IIIa inhibitors should not be given.
Covered stents may not be required.
Generally small concern of ischemia
DISTAL VESSEL PERFORATION
40.
CAUSES
Inadvertent advancement of guidewires, balloon,
microcatheter into a distal vessel
Stiff, tapered and polymer jacketed wires more likely
PREVENTION
Attention to guidewire position during equipment
delivery or when using multiple guidewires
Exchange jacketed wire with workhorse wire
41.
TREATMENT
1. Balloon inflation: balloon inflated proximally to
stop bleeding into pericardium, pericardiocentesis
may be done if hemodynamic compromise
2. Assess for continued bleeding: after balloon
inflation if no bleeding, heparin reversed after taking
out all instruments,
Suction through a microcatheter may collapse vessel
and stop bleeding
3. Covered stent or Embolization
42.
EMBOLIZATION
Commonly done using FAT or COIL
Fat is preferred in most cases except in large
perforations, as it is universally available, low coast
and biologically compatible
Delivery is not as controlled as for a coil.
43.
BASIC STEPS
1. Temporarily balloon deflation and second
guidewire advancement
2. Balloon reinflation
3. Balloon deflation and microcatheter delivery
4. Balloon reinflation and localization of perforation by
giving contrast through microcatheter
5, Embolization
44.
Choosing the microcatheter
Fat can be delivered through any microcatheter
For coil appropriate choice of the microcatheter is
important
Most coils available are compatible with 0.018 in.
microcatheter and can not be delivered through 0.014
in. catheters
Nneurovascular coils compatible with 0.014 in.
catheters are available.
45.
Microcatheters and their compatibility with the “Block
and Deliver” technique using guiding catheters of
different diameters.
47.
Fat can be harvested by advancing a hemostat into
femoral arteriotomy site, larger pieces cut into
smaller by scalpel.
Fat dipped into contrast for 1 min to make it
radiopaque
Loaded into microcatheter and the hub is turned
upside down to facilitate loading.
Fat injected by flushing with saline.
Several pieces may be required
FAT EMBOLIZATION
49.
Coiling is very infrequent in the cardiac
catheterization laboratory, achieving familiarity with
how to deliver and deploy a coil before a
complication occurs can significantly facilitate
management.
Coils are usually made of stainless steel or platinum
alloys and some of them have polymers or synthetic
wool or dacron fibers attached along the length of
the wire to increase thrombogenicity.
COIL EMBOLIZATION
50.
Once advanced into the target vessel, the coils
assume a preformed shape, sealing the perforation.
Particular attention needs to be made when coiling
branches to prevent the coil from prolapsing into the
main vessel.
Having only one or two types of coils is sufficient
51.
There are two broad categories of coils according to
mechanism of release: pushable and detachable
Pushable coils are inserted into a microcatheter and
pushed with a coil pusher or the front end of a
guidewire until they exit into the vessel, hence
deployment can be unpredictable and is irreversible
Detachable coils are released using a dedicated
release device once their position into the target
vessel is confirmed; conversely if their position is not
satisfactory, they can be retrieved.
52.
There are also two broad categories of coils
according to the size of the delivery microcatheter.
Coils compatible with 0.018 in. microcatheters (such
as the Interlock [Boston Scientific], Azur [Terumo],
and Micronester [Cook]), cannot be delivered
through the standard microcatheters used during
CTO PCI with the exception of the Finecross, and
require change to a larger microcatheter, such as the
Progreat (Terumo), Renegade (Boston Scientific), or
Transit (Cordis).
53.
Coils compatible with 0.014 in. microcatheters (such
as Axium, Medtronic) are preferred, as they can be
delivered through the standard microcatheters used
for CTO PCI
54.
When the perforated vessel is too small or too
tortuous, advancing a guidewire into it may not be
feasible
Such cases could be treated with coiling of a more
proximal larger branch, but if the perforated vessel is
originating from a large vessel, occlusion of that
vessel can be undesirable
Alternative solution is implantation of a covered
stent over the origin of the perforated branch
COVERED STENTS
56.
Perforation of an epicardial collateral branch is a
serious complication of retrograde CTO PCI, as it can
rapidly lead to tamponade and may be particularly
difficult to control
Perforation of septal collaterals is unlikely to have
adverse consequences, although septal hematomas
and even tamponade have been reported
COLLETERAL VESSEL PERFORATION
57.
Incidence upto 6.9% in a single case series in patients
with a retrograde approach
Septal hematomas have caused asymptomatic
bigeminy and severe chest pain, appear as an echo-
free space in the interventricular septum on
transthoracic echocardiography and resolve
spontaneously.
Perforation into a cardiac chamber usually does not
cause complications.
SEPTAL COLLATERAL PERFORATION
58.
CAUSES
Aggressive septal guidewire crossings, specially a
microcatheter.
Selection of a very thin or torturous septal channels
Dilation of the septal channel
PREVENTIONS
Selection of adequate septal channel.
Caution with tip injection of contrast if wedged
position of microcath is suspected
59.
Avoid advancement of Crosair microcath untill
guidewire position has been ascertained
Equipment retrival after recanalization should be done
after collateral perforation has been ruled out
TREATMENT
Usually no treatment required
Advancing microcath usually stop bleeding
Negative pressure from wedged microcath
If temponase , coiling to be done.
60.
Riskier than septal collateral perforation, as it can
rapidly lead to tamponade.
Epicardial collateral wiring is not safer in patients
with prior CABG surgery as loculated hematoma can
occur
CAUSES
Aggressive guidewire and microcath advancement
EPICARDIAL COLLATERAL
PERFORATION
61.
PREVENTION
In contrast to septal collaterals, epicardial collaterals
should never be dilated.
Avoid microcath advancement in front of wire
TREATMENT
General perforation treatment
Balloon temponade and negative pressure from the
wedged microcath.
Embolization/coiling: should be on both sides of the
perforation
63.
In the past prior coronary bypass graft surgery was
considered protective from tamponade in patients in
whom perforation occurs
Loculated effusions can develop in these patients
that can compress various cardiac structures such as
the left atrium or the right ventricle
Such loculated effusions can be lethal, as they can be
impossible to reach and drain percutaneously
Therefore, perforations in prior CABG patients
should be immediately treated
Perforations in post CABG cases
66.
Take home message
CAP are potentially fatal but avoidable complications of
PCI
The incidence is fairly low
Can be avoided with careful handling of equipments
specially during complex interventions
High lndex of suspicion is the key
Stop the bleeding first
Prolonged balloon dilatation is always indicated
Worse outcomes if emergency surgery is needed.