Continuous renal replacement therapy (CRRT) has been established as the standard treatment for acute kidney injury (AKI) in critically ill pediatric patients. CRRT transformed from an adapted therapy into the standard of care for pediatric critical care nephrology in the mid-1980s. The document provides guidance on managing electrolyte imbalances during CRRT such as increasing fluid flow rates for azotemia, adding saline for hyponatremia, and giving electrolyte-free water for hypernatremia.

1. Continuous renal replacement
therapy
Dr. F. Ghane
Associate Professor of Pediatric Nephrology
Mashhad University of Medical sciences

2.  Continuous renal replacement therapy (CRRT) has been established
as the gold standard for management of critically ill pediatric
patients with acute kidney injury (AKI)
 In the mid-1980s, continuous renal replacement therapy (CRRT) has
transformed from an adapted therapy into the standard of care in
pediatric critical care nephrology

12. Management of electrolyte imbalances during CRRT
 Azotemia: Increase replacement fluid flow rate
 Hyponatremia: Add 70 mL 3% saline L to a 5-L bag
 Hypernatremia: Give electrolyte-free water by increasing peripheral infusion of 5%
dextrose or 0.45% saline
 Hypercalcemia: