Low pressure measurements between 0.1" H2O and 25" H2O are commonly used in HVAC, medical, and research applications. When making these measurements, precautions must be taken to avoid overpressuring the sensitive pressure sensors, which can reduce accuracy or cause damage. Proper installation using valves is recommended to allow for safe pressurization and removal of differential pressure sensors, especially in liquid systems. Temperature variations and ensuring media compatibility are also important considerations for accurate low pressure measurement.