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Congenital Pyloric Stenosis
Made by : Esam muhsin
: Ameer
azeez
21/03/2017
Gastric Outlet Obstruction
• is non-bilious vomiting
• Other signs include abdominal distention
and bleeding from secondary inflammation
• Most common cause of non-bilious
vomiting is infantile hypertrophic pyloric
stenosis
Pyloric Stenosis
• First described by Hirschsprung in 1888
• Ramstedt described an operative
procedure to alleviate the condition in
1907 – the procedure used to this day to
treat pyloric stenosis
Pyloric Stenosis
• 3/1000 live births – frequency may be increasing
• Most common in whites of Northern European
ancestry, less common in African Americans
and rare in Asians
• Four times more common in males – especially
firstborn
• Increased in infants with type B or O blood
groups
Etiology
• Cause is unknown, but abnormal muscle
innervation, breast feeding and maternal
stress in the 3rd
trimester have been
implicated
• Elevated serum PG’s, reduced levels of
pyloric nitric oxide synthase and infant
hypergastrinemia have been found
Clinical Manifestations
• Non-bilious vomiting is the initial symptom
• May or may not be projectile initially
• Usually progressive, occurs immediately
after a feeding
• Vomiting usually starts after 3 wks of age,
but may develop as early as 1st
week and
as late as the 5th
month
Clinical Manifestations
• After vomiting, infant is hungry and wants
to feed again
• Progressive loss of fluid, hydrogen ion and
chloride leads to a hypochloremic
metabolic alkalosis.
• Serum K levels are maintained
• Greater awareness has led to earlier
diagnosis
Clinical Manifestations
• Jaundice occurs in 5% of infants with
pyloric stenosis – associated with a
decreased level of glucuronyl transferase
Diagnosis
Diagnosis
• Diagnosis traditionally made by palpation of
mass
• Firm, movable, approx 2 cm in length, olive
shaped and best palpated from the left
Mass located above and to the right of the
umbilicus in the midepigastrum beneath the liver
edge
• Peristaltic wave may be present prior to emesis
Treatment
• Preoperative treatment is directed toward
correcting the fluid/acid-base and
electrolyte imbalances.
• Correction of the alkalosis is essential to
prevent postoperative apnea
• Surgery is the treatment of choice –
Ramstedt pyloromyotomy
Treatment
• Ramstedt pyloromyotomy – performed through a
short transverse incision or laparoscopically
• Underlying pyloric mass is split without cutting
the mucosa and the incision is closed
• Post-op vomiting occurs in ½ the patients and
thought to be due to edema of the pylorus
• Feedings can usually be initiated within 12-24
hours
Treatment
• Persistent vomiting suggests an
incomplete pyloromyotomy, gastritis,
GERD.
• Surgical treatment is curative with a low
mortality rate
Thank you

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Congenital pyloric-stenosis

  • 1. Congenital Pyloric Stenosis Made by : Esam muhsin : Ameer azeez 21/03/2017
  • 2. Gastric Outlet Obstruction • is non-bilious vomiting • Other signs include abdominal distention and bleeding from secondary inflammation • Most common cause of non-bilious vomiting is infantile hypertrophic pyloric stenosis
  • 3. Pyloric Stenosis • First described by Hirschsprung in 1888 • Ramstedt described an operative procedure to alleviate the condition in 1907 – the procedure used to this day to treat pyloric stenosis
  • 4. Pyloric Stenosis • 3/1000 live births – frequency may be increasing • Most common in whites of Northern European ancestry, less common in African Americans and rare in Asians • Four times more common in males – especially firstborn • Increased in infants with type B or O blood groups
  • 5. Etiology • Cause is unknown, but abnormal muscle innervation, breast feeding and maternal stress in the 3rd trimester have been implicated • Elevated serum PG’s, reduced levels of pyloric nitric oxide synthase and infant hypergastrinemia have been found
  • 6. Clinical Manifestations • Non-bilious vomiting is the initial symptom • May or may not be projectile initially • Usually progressive, occurs immediately after a feeding • Vomiting usually starts after 3 wks of age, but may develop as early as 1st week and as late as the 5th month
  • 7. Clinical Manifestations • After vomiting, infant is hungry and wants to feed again • Progressive loss of fluid, hydrogen ion and chloride leads to a hypochloremic metabolic alkalosis. • Serum K levels are maintained • Greater awareness has led to earlier diagnosis
  • 8. Clinical Manifestations • Jaundice occurs in 5% of infants with pyloric stenosis – associated with a decreased level of glucuronyl transferase
  • 10. Diagnosis • Diagnosis traditionally made by palpation of mass • Firm, movable, approx 2 cm in length, olive shaped and best palpated from the left Mass located above and to the right of the umbilicus in the midepigastrum beneath the liver edge • Peristaltic wave may be present prior to emesis
  • 11. Treatment • Preoperative treatment is directed toward correcting the fluid/acid-base and electrolyte imbalances. • Correction of the alkalosis is essential to prevent postoperative apnea • Surgery is the treatment of choice – Ramstedt pyloromyotomy
  • 12. Treatment • Ramstedt pyloromyotomy – performed through a short transverse incision or laparoscopically • Underlying pyloric mass is split without cutting the mucosa and the incision is closed • Post-op vomiting occurs in ½ the patients and thought to be due to edema of the pylorus • Feedings can usually be initiated within 12-24 hours
  • 13. Treatment • Persistent vomiting suggests an incomplete pyloromyotomy, gastritis, GERD. • Surgical treatment is curative with a low mortality rate

Editor's Notes

  1. بيبسينوجين