This document discusses congenital heart defects, including atrial septal defects (ASD) and ventricular septal defects (VSD). It notes that congenital heart defects are caused by abnormal embryonic development and occur in approximately 1 in 125 births. ASDs and VSDs allow abnormal blood flow between the left and right sides of the heart and can cause heart failure if left untreated. They are typically repaired via catheterization or open heart surgery between ages 4-6 months. Post-operative care involves monitoring for complications and administering medications.
Valular heart disease is very common in most of Afro Asian counteries mainly due to Rheumatic heart disease..Definitive treatment is surgery.which may be valve replacement or reapir. In this ppp I have discussed this subject in a simple way
A brief History of Coronary Artery Bypass Grafting (CABG)Abhijit Joshi
this presentation traces the early reports of angina, when it was thought to be a disease of the breast, goes on to describe the stepping stones leading to myocardial revascularisation.
The heart contains 4 chambers: the right atrium, left atrium, right ventricle, and left ventricle. The atria are smaller than the ventricles and have thinner, less muscular walls than the ventricles. The ventricles are connected to the arteries that carry blood away from the heart.
Heart valve replacement surgery procedurePeter D'Souza
Heart valve replacement surgery is a surgical procedure by which cardiac surgeons eliminate a damaged heart valve & replace it with grafts or portions from body tissues or with artificial heart valves to improve the normal functioning of the heart. https://goo.gl/gg6JsJ
Valular heart disease is very common in most of Afro Asian counteries mainly due to Rheumatic heart disease..Definitive treatment is surgery.which may be valve replacement or reapir. In this ppp I have discussed this subject in a simple way
A brief History of Coronary Artery Bypass Grafting (CABG)Abhijit Joshi
this presentation traces the early reports of angina, when it was thought to be a disease of the breast, goes on to describe the stepping stones leading to myocardial revascularisation.
The heart contains 4 chambers: the right atrium, left atrium, right ventricle, and left ventricle. The atria are smaller than the ventricles and have thinner, less muscular walls than the ventricles. The ventricles are connected to the arteries that carry blood away from the heart.
Heart valve replacement surgery procedurePeter D'Souza
Heart valve replacement surgery is a surgical procedure by which cardiac surgeons eliminate a damaged heart valve & replace it with grafts or portions from body tissues or with artificial heart valves to improve the normal functioning of the heart. https://goo.gl/gg6JsJ
If you've had a heart attack, you may have already had certain procedures to help you survive your heart attack and diagnose your condition. For example, many heart attack patients have undergone thrombolysis, a procedure that involves injecting a clot-dissolving agent to restore blood flow in a coronary artery.
A cyanotic heart defect is a group-type of congenital heart defects (CHDs). The patient appears blue (cyanotic), due to deoxygenated blood bypassing the lungs and entering the systemic circulation. This can be caused by right-to-left or bidirectional shunting, or malposition of the great arteries.
Cyanotic heart defects, which account for approximately 25% of all CHDs, include:
Tetralogy of Fallot (ToF)
Total anomalous pulmonary venous connection
Hypoplastic left heart syndrome (HLHS)
Transposition of the great arteries (d-TGA)
Truncus arteriosus (Persistent)
Tricuspid atresia
Interrupted aortic arch
Pulmonary atresia (PA)
Pulmonary stenosis (critical)
Eisenmenger syndrome(Reversal of Shunt due to Pulmonary Hypertension) .
Patent ductus arteriosus may cause cyanosis in late stage.
Neha diwan presentation on aortic aneurysmNEHAADIWAN
An aortic dissection is a serious condition in which a tear occurs in the inner layer of the body's main artery (aorta).Aortic rupture is when all the layers of the aorta wall tear, causing blood to leak out from the aorta often due to a large aortic aneurysm that bursts. This will stop blood being pumped around the body and is life threatening. Ideally an aortic aneurysm will be repaired before a rupture can occur.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
2. CONGENITAL HEART DISEASE:
▪ Congenital cardiac malformations resulting from defective embryonic
development without obvious cause.
▪ Between 3-8 weeks “gestation” - the fetal heart structures are formed
“organogenesis”
3. INCIDENCE:
1/125 live births in approximately.
Most common birth defect.
Incidence is more in :-
a-Premature
b-abortions
c-still births
Incidence increased for siblings.
5. ACYANOTIC CHD:
▪ Pink Baby (L → R shunt)
▪ L → R shunts cause CHF and pulmonary hypertension.
▪ This leads to RV enlargement, RV failure
▪ These babies present with CHF and respiratory distress.
▪ They are not typically cyanotic
▪ Examples: Atrial Septal Defect (ASD)
Ventricular Septal Defect (VSD)
Patent Ductus Arteriosus (PDA)
9. TYPES OF ASD:
▪ OSTIUM SECUNDUM ASD: Defect in the middle of the atrial septum.
▪ OSTIUM PRIMUM ASD: Defect in the lower part of the atrial septum.
▪ SINUS VENOUS ASD: Defect in the upper part of the atrial septum near
where a large vein brings Oxygen poor blood from upper body to RA.
▪ CORONARY SINUS ASD: Located within the walls of the coronary sinus.
12. MANAGEMENT:
▪ 20% Of ASD will close spontaneously in the first year of life.
▪ ASD may close spontaneously as a child grows.
▪ Usually, an ASD will be repaired if it has not closed on its own by the time the
child starts school- to prevent lung problems that will develop from long time
exposure to extra blood flow.
▪ Pulmonary arteries become thickened and obstructed due to increased flow,
from L to R for many years.
13. MEDICAL MANAGEMENT :
▪ While medicines cannot cure an ASD, they may be used to control symptoms until
the hole either closes on its own or until it can be closed using a cath based or
surgical procedure. The main medications used are;
DIGOXIN: Helps strength the heart muscle enabling to pump more efficiently.
DIURETICS: Relieve pulmonary congestion.
ANTI-COAGULANTS: Reduce the risk of blood clots.
AFTER LOAD REDUCING AGENTS.
14. CONT…
▪ INFECTION CONTROL: Prophylactic antibiotics to prevent bacterial
endocarditis before dental procedure and other invasive procedures.
▪ NUTRITIONAL MGT:
▪ ADEQUATE NUTRITION:
▪ High calorie formula or breast milk.
▪ Supplemental tube feedings.
15. SURGICAL MGT:
▪ PRE OP MGT:
▪ Informed consent is a legal document that explains the tests, treatments, or
procedures that you may need.
▪ Blood tests.
▪ NPO.
▪ An IV is a small tube placed in your vein that is used to give you medicine or
liquids.
▪ General anaesthesia.
▪ A Foley catheter.
17. PERCUTANEOUS CLOSURE:
TRANSCATHETER MGT: Right heart cath is done.
▪ This technique involves implantation of one of several devices using cardiac
catheterization.
▪ CARDIAC CATHETERIZATION - involves slowly moving a catheter (a long,
thin, flexible, hollow tube) into the heart. The catheter is initially inserted into a
large vein through a small incision made usually in the inner thigh (groin area)
and then is advanced into the heart.
18. CONT…
An ASD closure device is moved
through the catheter to the heart and
specifically to the location of the
heart wall defect. Once in the correct
location, ASD closure device is
pushed out of the catheter.
The device open and expand it shape
to sit each side of the hole. It stops
the abnormal flow of blood between
the two atria chambers of the heart.
19. CONT…
▪ Catheter is removed and procedure is completed.
▪ Within a few days, the body’s own tissue will begin to grow over the device.
By 3 to 6 months, the device is completely covered by heart tissue and at that
point becomes a part of the wall of the patient’s heart.
23. OPEN HEART PROCEDURE:
▪ SURGICAL PROCEDURE:
Done to repair primum or sinus venosus ASD.
INCISION: MEDIAN STERNOTOMY.
SURGERY: OPEN HEART SURGERY.
CPB MACHINE is used. The right atrium is then opened to allow access to the atrial
septum below.
DEFECT may be closed with STITCHES(IF THE DEFECT IS TOO SMALL) or a
SPECIAL PATCH(IF THE DEFECT IS TOO LARGE).
The material utilized for a patch closure of ASD’s may be the patient’s own
pericardium, commercially bovine or synthetic material. Eventually tissue of the heart
heals by 6 months.
25. CONT…
▪ POST OP MGT:
▪ Chest tubes may be put into chest during surgery. They are used to remove
air, blood, or fluid from around lungs or heart.
▪ To wear pressure stockings or inflatable boots after surgery.
▪ Deep breathing and coughing.
▪ To eat and drink gradually after surgery.
▪ REGULAR FOLLOW UP.
31. TYPES OF VSD:
MUSCULAR VSD:
Common type of VSD.
Opening in the muscular portion of lower section of ventricular septum.
Closes spontaneously and don’t require surgery.
32. CONT…
PERIMEMBRANOUS VSD:
Opening in an area of upper section of the ventricular septum called the
membranous septum, located near valves.
Treated by surgery.
ATRIOVENTRICULAR CANAL TYPE VSD:
Associated with AV canal defect.
VSD is located underneath the tricuspid and mitral valves.
33. CONT…
OUTLET VSD:
Found in part of the ventricle where the blood leaves the heart.
Rare type of VSD.
CONAL SEPTAL VSD:
Subarterial, Supracristal, Infundibular.
Rarest VSD.
Occurs in the ventricular septum just below the aortic valve.
Effect from L to R shunt causing aortic valve leaflet to prolapse into VSD resulting in
aortic valve regurgitation.
36. TREATMENT:
INDICATIONS FOR SURGERY:
▪ If VSD remains large and unrestrictive-surgical closure at age
4 to 6 months.
VSD with pulmonary stenosis.
Large VSD with pulmonary HTN.
VSD with aortic regurgitation.
38. CONT…
▪ NUTRITIONAL MGT:
▪ ADEQUATE NUTRITION:
▪ High calorie formula or breast milk.
▪ Supplemental tube feedings.
39. CONT…
▪ PRE OP MGT:
▪ Informed consent is a legal document that explains the tests, treatments, or
procedures that you may need.
▪ Blood tests.
▪ NPO.
▪ An IV is a small tube placed in your vein that is used to give you medicine or
liquids.
▪ General anaesthesia.
▪ A Foley catheter.
40. MANAGEMENT:
▪ SURGICAL MGT:
TRANSCATHETER CLOSURE: Cardiac cath is done.
Device used to close the hole is moved through the catheter to the heart and specifically to
the location of the heart wall defect. Once in the correct location, VSD closure device is
pushed out of the catheter.
The device open and expand it shape to sit each side of the hole. It stops the abnormal
flow of blood between the two VENTRICULAR chambers of the heart.
41. CONT…
▪ Catheter is removed and procedure is completed.
▪ The device will remain in the heart permanently closing the hole in the heart
wall.
▪ Full closure of the ventricular defect within the 24hrs of placement.
42. TYPES OF VSD CLOSURE:
▪ AMPLATZER MUSCULAR VSD OCCLUDER:
44. SURGICAL MGT:
▪ Surgical closure of a perimembranous VSD is performed on CPB.
▪ Incision: Median sternotomy.
▪ Surgery: Open heart surgery.
▪ Surgical exposure is achieved through the right atrium. The tricuspid valve septal
leaflet is retracted or incised to expose the defect.
▪ Defect is closed by sewn a patch native or bovine pericardium.
▪ Suture techniques: horizontal pledged mattress sutures and running polypropylene
suture.
45. CONT…
▪ Critical attention is necessary to avoid injury to the conduction system.
▪ Care is given to avoid injury to aortic valve with sutures.
▪ Intraoperative TEE is used to confirm secure closure of the VSD, normal
functioning of aortic and tricuspid valves,good ventricular function.
▪ The sternum, fascia and skin are closed.
46. CONT…
▪ POST OP MGT:
▪ Chest tubes may be put into chest during surgery. They are used to remove air,
blood, or fluid from around lungs or heart.
▪ To wear pressure stockings or inflatable boots after surgery.
▪ Deep breathing and coughing.
▪ To eat and drink gradually after surgery.
▪ REGULAR FOLLOW UP.